technetium-tc-99m-medronate and Splenic-Diseases

Melioidosis is an infectious disease caused by Pseudomonas pseudomallei. It is seldom diagnosed promptly and, if untreated, can lead to an 80-100% mortality rate. Twenty-eight patients with melioidosis were identified over a 6 year period, and their imaging patterns were analysed. Respiratory infections were the commonest form of presentation, frequently shown as diffuse airspace consolidation, and accounted for the highest mortality. Visceral and musculoskeletal infections were associated with chronicity and a high relapse rate. Multifocal splenic abscesses were a common occurrence. Septic arthritis of the knee was frequently seen. The majority of patients had diabetes mellitus and chronic ill-health. An increased awareness of the disease can contribute to its early detection and appropriate treatment.

Topics: Abscess; Adult; Aged; Diagnostic Imaging; Female; Humans; Lung Diseases; Magnetic Resonance Imaging; Male; Melioidosis; Middle Aged; Pneumonia, Bacterial; Radionuclide Imaging; Retrospective Studies; Splenic Diseases; Technetium Tc 99m Medronate; Tomography, X-Ray Computed; Ultrasonography

Considerable accumulation of Tc-99m HMDP was noted in a huge splenic mass in a 62-year-old man with hepatocellular carcinoma. An autopsy revealed a massive hemorrhage within the splenic metastasis. The splenic uptake of the radionuclide corresponded to the marked deposition of hemosiderin.

Topics: Carcinoma, Hepatocellular; Hemorrhage; Hemosiderin; Humans; Liver Neoplasms; Male; Middle Aged; Radionuclide Imaging; Spleen; Splenic Diseases; Splenic Neoplasms; Technetium Tc 99m Medronate

Topics: Diphosphonates; Humans; Radionuclide Imaging; Spleen; Splenic Diseases; Technetium; Technetium Tc 99m Medronate