technetium-tc-99m-medronate and Pyelonephritis

A 5-year-old girl had intermittent fever for 4 months. A Tc MDP bone scintigraphy was performed to evaluate possible occult osteomyelitis, which revealed no bone lesion. However, abnormal MDP activity in the upper poles of both kidneys was noted, which was confirmed as pyelonephritis subsequently.

Topics: Bone and Bones; Child, Preschool; Female; Humans; Incidental Findings; Pyelonephritis; Radionuclide Imaging; Technetium Tc 99m Medronate

Topics: Adolescent; Bone and Bones; Humans; Male; Osteomyelitis; Pyelonephritis; Radiopharmaceuticals; Ribs; Technetium Tc 99m Medronate; Tomography, Emission-Computed, Single-Photon

Topics: Child; Humans; Kidney; Male; Pyelonephritis; Radionuclide Imaging; Sepsis; Shock, Septic; Streptococcal Infections; Technetium Tc 99m Medronate

A 6-year-old boy presented with an inflammatory syndrome. Because Tc-99m MDP bone scintigraphy revealed increased tracer uptake at the upper pole of the right kidney, further studies were oriented towards a diagnosis of renal or adrenal pathology. I-123 metaiodobenzylguanidine (MIBG) accumulated at the site of the abnormal MDP uptake. The diagnosis of neuroblastoma or allied disorder was excluded on the basis of other investigations and further evaluation, suggesting that the MIBG uptake was a false-positive. Findings on clinical imaging, laboratory findings, Tc-99m DMSA imaging, sonography, and CT scanning were highly suggestive of acute focal pyelonephritis.

Topics: 3-Iodobenzylguanidine; Acute Disease; Child; Humans; Iodine Radioisotopes; Iodobenzenes; Kidney; Male; Pyelonephritis; Radionuclide Imaging; Technetium Tc 99m Medronate