technetium-tc-99m-medronate and Peritoneal-Neoplasms

Heterotopic ossification is a rare phenomenon that refers to formation of bone outside the skeletal system. We present a 61-year-old woman who suffered from peritoneal cancer surgery 2 years ago, referred for Tc-MDP bone scan because of higher serum CA-125 level, which showed multiple intense tracer activities in her abdominal and pelvic region without other abnormalities. SPECT/CT revealed the activities were loaded in the intestine but not in the bone. A wait-and-see policy was adopted because of no abdominal discomfort. After 1-year follow-up, another bone scintigraphy showed the tracer uptake was significantly decreased.

Topics: Bone and Bones; Female; Humans; Intestines; Middle Aged; Ossification, Heterotopic; Peritoneal Neoplasms; Single Photon Emission Computed Tomography Computed Tomography; Technetium Tc 99m Medronate

Altered biodistribution of Tc-99m methylene diphosphonate is a common occurrence on bone scintigraphy and mucin-producing neoplasms of the gastrointestinal tract are associated with dystrophic uptake. In addition to the uptake in the primary tumor, activity has been reported in metastasis within lymph nodes and liver. We present a case of Tc-99m methylene diphosphonate uptake in peritoneal carcinomatosis and metastatic Krukenberg tumors from a primary mucinous adenocarcinoma of the descending colon. Each of these findings is uncommon and their combination in this case is particularly unique.

Topics: Adenocarcinoma, Mucinous; Female; Humans; Krukenberg Tumor; Middle Aged; Peritoneal Neoplasms; Radionuclide Imaging; Technetium Tc 99m Medronate; Tomography, X-Ray Computed

Topics: Aged; Breast Neoplasms; Carcinoma, Ductal; Female; Humans; Peritoneal Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Whole Body Imaging

Topics: Cecal Neoplasms; Humans; Male; Middle Aged; Omentum; Peritoneal Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate

Osteotropic radiopharmaceutical uptake has been reported in a wide variety of benign and malignant soft tissue tumors. We present an unusual case of pancreaticoblastoma with mesenteric and omental metastases detected by bone scan in a 69-year-old man who presented with fever, weight loss, and renal insufficiency. Pancreaticoblastoma is a rare childhood tumor that may occur in adults, although only two cases of adults with metastatic disease have been described.

Topics: Aged; Humans; Male; Mesentery; Omentum; Pancreatic Neoplasms; Peritoneal Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Whole-Body Counting

Topics: Aged; Bone and Bones; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Peritoneal Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Rupture; Technetium Tc 99m Medronate

Topics: Abdomen; Aged; Anti-Bacterial Agents; Cervical Vertebrae; Diagnosis, Differential; Enterocolitis, Pseudomembranous; Female; Hemorrhage; Humans; Osteomyelitis; Peritoneal Neoplasms; Radiography; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Whole-Body Counting

Topics: Adenocarcinoma, Papillary; Calcinosis; Female; Humans; Middle Aged; Ovarian Neoplasms; Peritoneal Neoplasms; Radiopharmaceuticals; Technetium Tc 99m Medronate; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

Topics: Adult; Humans; Male; Mesothelioma; Peritoneal Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate

Topics: Adenocarcinoma; Aged; Citrates; Female; Gallium; Gallium Radioisotopes; Humans; Peritoneal Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Uterine Cervical Neoplasms

Topics: Humans; Mesothelioma; Middle Aged; Peritoneal Neoplasms; Radionuclide Imaging; Technetium Tc 99m Medronate

Tc-99m MDP bone scintigraphy is widely used for initial staging and subsequent follow-up of patients with osteosarcoma. Two unusual cases are presented here, one with diffuse pleural metastases and one with diffuse peritoneal metastases. In one case, an abnormal bone scan was the first indication of metastatic disease. Both the metastatic pattern of osteosarcoma and the indications for bone scintigraphy are reviewed.

Topics: Adolescent; Adult; Femoral Neoplasms; Humans; Male; Osteosarcoma; Peritoneal Neoplasms; Pleural Neoplasms; Radionuclide Imaging; Technetium Tc 99m Medronate

In a 45-year old patient with serous cystadenocarcinoma of the ovary CT showed small calcifications in metastases along peritoneal surfaces. These "psammoma bodies" indicated abdominal implants, which in other respects would not have been demonstrable via CT scans because of their small size. During bone scintigraphy the calcifications caused unusual extraskeletal focal uptake of 99mTc-MDP in the abdomen.

Topics: Bone Neoplasms; Calcinosis; Cystadenocarcinoma; Female; Humans; Middle Aged; Ovarian Neoplasms; Peritoneal Neoplasms; Technetium Tc 99m Medronate; Tomography, X-Ray Computed

A patient with pseudomyxoma peritonei secondary to a mucin-secreting adenocarcinoma demonstrated striking, diffuse uptake of 99mTc-MDP throughout the abdomen. The radiopharmaceutical distribution accurately delineated the region of tumor involvement within the peritoneal cavity.

Topics: Adult; Diphosphonates; Humans; Male; Peritoneal Neoplasms; Radionuclide Imaging; Technetium; Technetium Tc 99m Medronate

Two cases of bone radiotracer uptake by primary hepatic malignancies of childhood hepatocellular carcinoma and hepatoblastoma and their metastases are presented. These cases are illustrative of a previously unreported cause of extraosseous uptake of bone seeking radionuclide.

Topics: Carcinoma, Hepatocellular; Child; Diphosphonates; Humans; Infant; Liver Neoplasms; Male; Peritoneal Neoplasms; Radionuclide Imaging; Soft Tissue Neoplasms; Technetium; Technetium Tc 99m Medronate