technetium-tc-99m-medronate and Periostitis

Florid reactive periostitis ossificans is a rare benign lesion usually affecting the tubular bones of the hands and feet, and its histological features may be confused with those of infection and osteosarcoma. We report a case with florid reactive periostitis ossificans of the femur showing increased tracer uptake on both Tc-MDP bone scan and F-FDG PET/CT mimicking a local recurrence in a 15-year-old patient with high-grade osteosarcoma.

Topics: Child; Diagnosis, Differential; Fluorodeoxyglucose F18; Humans; Male; Neoplasm Recurrence, Local; Osteosarcoma; Periostitis; Radionuclide Imaging; Technetium Tc 99m Medronate

While drug-related periostitis has been known of for many years, the specific association of diffuse periostitis with voriconazole (most frequently in transplant patients) has only been recently explicitly addressed in the literature. Recognition of the radiologic and clinical manifestations of voriconazole-related periostitis is important for helping to narrow an otherwise broad differential diagnosis. We present two cases that illustrate different radiologic presentations of this painful cause of diffuse periostitis. Case 1 features a 60 year-old woman with a history of orthotopic heart transplant who was hospitalized for "full body pain" with progressively worsening bone tenderness involving the humeri, knees, femurs, hips, and hands. Case 2 describes a 48 year-old man with a history of acute lymphoblastic leukemia status post stem cell transplant who presented with diffuse arthralgias involving bilateral ankles, knees, wrists, and elbows.

Topics: Antifungal Agents; Female; Heart Transplantation; Humans; Male; Middle Aged; Opportunistic Infections; Periostitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pulmonary Aspergillosis; Pyrimidines; Radionuclide Imaging; Radiopharmaceuticals; Stem Cell Transplantation; Technetium Tc 99m Medronate; Tomography, X-Ray Computed; Triazoles; Voriconazole

Topics: Adult; Bone and Bones; Humans; Magnetic Resonance Imaging; Male; Muscle, Skeletal; Myositis; Periostitis; Polyarteritis Nodosa; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate

Topics: Athletic Injuries; Femur; Humans; Knee Joint; Muscle, Skeletal; Muscular Diseases; Periostitis; Radioisotopes; Rheumatic Diseases; Running; Syndrome; Technetium Tc 99m Medronate; Tomography, Emission-Computed

Takayasu's arteritis (TA) is a vasculitis of large and medium sized arteries. Involvement of bone in TA is very rare. We report a case of young woman who presented with multiple painful bone lesions which were identified as periostitis with new bone formation associated with TA. Our case is unique in that bony involvement in TA could occur independent of vascular stenosis.

Topics: Adult; Female; Forearm; Humans; Leg; Pain; Periostitis; Radionuclide Imaging; Radius; Takayasu Arteritis; Technetium Tc 99m Medronate; Tibia; Ulna

Topics: Adult; Cumulative Trauma Disorders; Elbow; Elbow Injuries; Forearm Injuries; Humans; Male; Periostitis; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Ulna; Weight Lifting

Unilateral lower extremity hypertrophic osteoarthropathy may be the initial symptom of an infected aortic graft. Knowledge of this uncommon association should lead to early and accurate diagnosis and appropriate surgical management, thus avoiding the development of aortoenteric fistula, a complication that still carries a significant risk of mortality.

Topics: Aged; Aorta; Blood Vessel Prosthesis; Fatal Outcome; Femoral Artery; Humans; Intermittent Claudication; Male; Osteoarthropathy, Secondary Hypertrophic; Periostitis; Prosthesis-Related Infections; Radiography; Radionuclide Imaging; Technetium Tc 99m Medronate

Topics: Adult; Baseball; Cumulative Trauma Disorders; Humans; Humerus; Male; Periostitis; Radionuclide Imaging; Technetium Tc 99m Medronate; Tennis

Topics: Adult; Bone and Bones; Female; Humans; Periostitis; Radionuclide Imaging; Syphilis; Syphilis, Cutaneous; Technetium Tc 99m Medronate

Topics: Actinomycosis; Adult; Humans; Male; Periostitis; Radionuclide Imaging; Ribs; Technetium Tc 99m Medronate

The scintigraphic findings on bone imaging in two patients with extensive lower extremity periostitis secondary to venous insufficiency are presented. One of these patients had bilateral disease. The use of [67Ga]citrate scanning in an attempt to exclude concurrent osteomyelitis is also addressed.

Topics: Aged; Aged, 80 and over; Female; Gallium Radioisotopes; Humans; Leg; Middle Aged; Periostitis; Radionuclide Imaging; Technetium Tc 99m Medronate; Venous Insufficiency

We report a case of early syphilis with multiple bone lesions which all resolved after treatment with penicillin. We discuss why bone lesions may be more prevalent than generally believed and why 99m-Tc-MDP-bone scintigraphy is more sensitive than radiography in detecting syphilitic periostitis.

Topics: Adult; Bone and Bones; Diphosphonates; Humans; Male; Periostitis; Radionuclide Imaging; Syphilis; Technetium; Technetium Tc 99m Medronate