technetium-tc-99m-medronate and Pancreatitis

Pancreatitis, panniculitis, and polyarthritis syndrome is a rare disease. A 49-year-old man recently complained of bilateral ankle and epigastric pain. An ankle x-ray showed subcutaneous soft tissue swelling. Subsequent 99mTc-MDP bone scan showed foci of abnormal activity around joints in all extremities, especially in the knees and ankles. In addition, multiple nodular calcifications in the head of the pancreas were found in the abdominal CT scan. The patient also had increased blood amylase and lipase. The symptoms were resolved after the treatment of his pancreatitis.

Topics: Abdominal Pain; Arthritis; Humans; Male; Middle Aged; Pancreatitis; Panniculitis; Technetium Tc 99m Medronate; Tomography, X-Ray Computed

Pancreatic disease can be associated with polyarthritis and panniculitis in a small number of patients, and this triad constitutes PPP syndrome. Early diagnosis is critical as it has high morbidity and mortality. Panniculitis can occur in fat present anywhere in the body. Involvement of fat in bone marrow is relatively uncommon, and radiologic imaging shows osteolytic lesions involving long bones. Here we present a case of acute pancreatitis, referred to our department for evaluation of severe joint pain and multiple bone pain. Tc-MDP scan with SPECT/CT has been done, which showed medullary expansion with heterogenous tracer uptake, that is, moth-eaten appearance.

Topics: Acute Disease; Bone and Bones; Fat Necrosis; Humans; Male; Pain; Pancreatitis; Single Photon Emission Computed Tomography Computed Tomography; Technetium Tc 99m Medronate

Topics: Aged; Bone and Bones; Bone Neoplasms; Calcinosis; Chronic Disease; Female; Humans; Pancreatitis; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Tomography, X-Ray Computed; Uterine Cervical Neoplasms

Topics: Aged; Bone and Bones; Colloids; Female; Humans; Iohexol; Liver; Pancreatitis; Radiography, Abdominal; Radionuclide Imaging; Spleen; Technetium Tc 99m Medronate; Tomography, X-Ray Computed