technetium-tc-99m-medronate and Muscular-Dystrophy--Duchenne

Bone scintigraphy was performed on a 6-year-old boy with possible sacroiliitis.. Extraosseous uptake in the region of the paraspinal, psoas and calf muscles was noted and suggested myositis. Subsequently, his creatine kinase level was found to be elevated. Results of a neuromuscular examination, muscle biopsy with dystrophin immunostaining, and a multiplex polymerase chain reaction led to the diagnosis of Becker muscular dystrophy.. A patient with Becker muscular dystrophy had several distinct areas of myositis localized by bone scintigraphy. Pathologic features including focal myonecrosis and regeneration may contribute to this scintigraphic picture.

Topics: Bone and Bones; Child; Humans; Male; Muscular Dystrophy, Duchenne; Myositis; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate