technetium-tc-99m-medronate and Hemorrhage

We report the case of a girl with known large right-sided and small left-sided neonatal adrenal haematomas who underwent bone scintigraphy 23 days after birth for suspected osteomyelitis. The radionuclide examination showed uptake of bone tracer around the right-sided haematoma, but no abnormality on the left side.

Topics: Adrenal Gland Diseases; Adrenal Glands; Bone and Bones; Female; Hematoma; Hemorrhage; Humans; Infant, Newborn; Osteomyelitis; Radiography; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Ultrasonography; Whole-Body Counting

Topics: Abdomen; Aged; Anti-Bacterial Agents; Cervical Vertebrae; Diagnosis, Differential; Enterocolitis, Pseudomembranous; Female; Hemorrhage; Humans; Osteomyelitis; Peritoneal Neoplasms; Radiography; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Whole-Body Counting

Topics: Hemorrhage; Humans; Lung Diseases; Male; Middle Aged; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate

Considerable accumulation of Tc-99m HMDP was noted in a huge splenic mass in a 62-year-old man with hepatocellular carcinoma. An autopsy revealed a massive hemorrhage within the splenic metastasis. The splenic uptake of the radionuclide corresponded to the marked deposition of hemosiderin.

Topics: Carcinoma, Hepatocellular; Hemorrhage; Hemosiderin; Humans; Liver Neoplasms; Male; Middle Aged; Radionuclide Imaging; Spleen; Splenic Diseases; Splenic Neoplasms; Technetium Tc 99m Medronate

We have studied core biopsy specimens from 16 femoral heads affected by idiopathic avascular necrosis at the silent stage, when there were no clinical or radiographic manifestations but scintigraphy was positive. All the specimens showed necrosis of trabeculae and of bone marrow, but the most common and characteristic feature was evidence of old and new haemorrhage in the marrow. In the areas of intramedullary haemorrhages, trabeculae and bone marrow were completely necrotic, with a transitional area of incomplete necrosis between these areas and those without haemorrhagic lesions, where the trabeculae and bone marrow were normal. There was good correlation between necrosis and haemorrhagic episodes, and it was concluded that repeated intramedullary haemorrhage at the silent stage is probably related to the pathogenesis of idiopathic avascular necrosis of the femoral head.

Topics: Adolescent; Adult; Biopsy; Bone Marrow; Bone Marrow Diseases; Female; Femur Head Necrosis; Hemorrhage; Humans; Male; Middle Aged; Radionuclide Imaging; Technetium Tc 99m Medronate

Topics: Adult; Anticoagulants; Female; Hand; Hemorrhage; Humans; Radionuclide Imaging; Self Medication; Technetium Tc 99m Medronate; Thigh; Thrombophlebitis