technetium-tc-99m-medronate and Cystadenocarcinoma

Topics: Bone and Bones; Calcinosis; Cystadenocarcinoma; Female; Humans; Ovarian Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Umbilicus

An ovarian mucinous cystadenocarcinoma which moderately accumulated Tc-99m MDP was imaged during a whole body bone scan. The primary tumor and its implants in the peritoneal cavity were both visualized and correlated with US and TCT scan findings. As a result, the radiopharmaceutical distribution accurately delineated the primary tumor and the region of tumor involvement within the peritoneal cavity. Therefore, a whole body bone scan offers a potential method for assessing neoplastic size and spread.

Topics: Aged; Aged, 80 and over; Cystadenocarcinoma; Female; Humans; Ovarian Neoplasms; Pseudomyxoma Peritonei; Radionuclide Imaging; Technetium Tc 99m Medronate; Tomography, X-Ray Computed; Ultrasonography

In a 45-year old patient with serous cystadenocarcinoma of the ovary CT showed small calcifications in metastases along peritoneal surfaces. These "psammoma bodies" indicated abdominal implants, which in other respects would not have been demonstrable via CT scans because of their small size. During bone scintigraphy the calcifications caused unusual extraskeletal focal uptake of 99mTc-MDP in the abdomen.

Topics: Bone Neoplasms; Calcinosis; Cystadenocarcinoma; Female; Humans; Middle Aged; Ovarian Neoplasms; Peritoneal Neoplasms; Technetium Tc 99m Medronate; Tomography, X-Ray Computed

Two cases of extra-osseous uptake of 99mTc-methylene diphosphonate (MDP) by non-osseous metastatic tumors are reported. One was a metastasis with ossification in the abdominal wall from carcinoma of the sigmoid colon and the other was a metastasis with calcification from an ovarian carcinoma. The mechanism of extra-osseous uptake of 99mTc-MDP is discussed. Bone scintigraphy can be a potential means to assess tumor spread with ossifications and calcifications.

Topics: Abdominal Neoplasms; Adenocarcinoma, Mucinous; Adult; Bone Neoplasms; Calcinosis; Cystadenocarcinoma; Female; Humans; Male; Middle Aged; Ovarian Neoplasms; Radionuclide Imaging; Sigmoid Neoplasms; Technetium Tc 99m Medronate

An unusual case of ovarian carcinoma is presented with extra-abdominal soft tissue metastasis. These demonstrate calcification on plain films and CT, as well as avid uptake of Tc-99m MDP.

Topics: Adult; Cystadenocarcinoma; Diphosphonates; Female; Humans; Ovarian Neoplasms; Radionuclide Imaging; Soft Tissue Neoplasms; Technetium; Technetium Tc 99m Medronate; Tomography, X-Ray Computed