technetium-tc-99m-mebrofenin and Biliary-Fistula

Topics: Aniline Compounds; Biliary Fistula; Biliary Tract; Bronchial Fistula; Glycine; Humans; Imino Acids; Liver; Male; Organotechnetium Compounds; Radionuclide Imaging; Young Adult

Topics: Adult; Aniline Compounds; Biliary Fistula; Biliary Tract; Colonic Diseases; Female; Glycine; Humans; Imino Acids; Liver; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Wounds, Nonpenetrating

Topics: Aged; Aged, 80 and over; Aniline Compounds; Biliary Fistula; Common Bile Duct; Female; Glycine; Humans; Imino Acids; Intestinal Fistula; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals

Endoscopic biliary drainage is effective in the management of patients with postoperative bile leak. Evidently, it cannot be used in patients with completely tied-off common bile duct (CBD).. To ascertain whether biliary excretion scintigraphy could reliably detect patients with tied-off CBD so that endoscopic retrograde cholangiography (ERC), an invasive test, could be avoided.. Twelve patients with active bile leak (11 postcholecystectomy, one posttraumatic), in whom the biliary system was imaged by both 99m technetium mebrofenin biliary scintigraphy and ERC, were evaluated.. Bile leak was demonstrated in all the 12 patients by scintigraphy. In six of these, there was no visualization of radionuclide activity in the intestines; in three of these six patients, ERC showed a patent CBD potentially amenable to endoscopic drainage, whereas in the remaining three, there was complete obstruction presumably due to CBD tie-off during surgery.. Biliary excretion scintigraphy is unreliable for detecting complete biliary obstruction in patients with bile leak.

Topics: Adult; Aniline Compounds; Bile; Biliary Fistula; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Common Bile Duct; Female; Glycine; Humans; Imino Acids; Male; Organotechnetium Compounds; Postoperative Complications; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals