technetium-tc-99m-lidofenin and Testicular-Neoplasms

A case of multiple primary cancers, hepatoma and seminoma, was detected by 67Ga citrate and 99mTc-HIDA scintigraphy. 67Ga citrate accumulated in the chest wall, the hepatic lesion and the testis. 99mTc-HIDA accumulated in the chest wall. Therefore we suspected that the chest wall lesion was a tumor metastasized from hepatocellular carcinoma and another cancer was present in the testis. After these examinations orchiectomy and needle biopsy were done. Pathologically, the testicular tumor was seminoma and hepatic and chest wall tumors were hepatocellular carcinoma (Edmondson-II).

Topics: Carcinoma, Hepatocellular; Citrates; Citric Acid; Dysgerminoma; Gallium Radioisotopes; Humans; Imino Acids; Liver Neoplasms; Male; Middle Aged; Neoplasms, Multiple Primary; Organotechnetium Compounds; Radionuclide Imaging; Technetium Tc 99m Lidofenin; Testicular Neoplasms

16 patients with a history or suspicion of malignant disease were investigated scintigraphically for liver metastases. Each patient was studied with 99mTc-HIDA and 99mTc-sulphur- or tin-colloid. In 4 patients liver metastases were suspected and confirmed by ultrasonography and/or computerized tomography. The filling defects were visible with 99mTc-colloids and 99mTc-HIDA as well. Likewise both radiopharmaceuticals coincided in their parenchymal activity patterns in the nonsuspicious livers. Because of this good agreement the morphologic aspect of basically functional 99mTc-HIDA examinations is emphasized.

Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Hodgkin Disease; Humans; Imino Acids; Liver Neoplasms; Male; Middle Aged; Radionuclide Imaging; Skin Neoplasms; Technetium; Technetium Tc 99m Lidofenin; Teratoma; Testicular Neoplasms