technetium-tc-99m-lidofenin and Intestinal-Diseases

Symptoms from the gastro-intestinal tract are common and often difficult to evaluate. Specialised examination techniques are available only at a limited number of clinics. A technique based on biliary scintigraphy when measuring the transit of contents through the small intestine has been developed. The investigation is simple to perform and convenient for the patient. It can be carried out at any clinic equipped with a gamma camera. 30 healthy individuals were examined in order to obtain reference values. 23 patients were examined with scintigraphy in combination with upper gastrointestinal manometry, 10 of whom had abdominal pain and neurogenic or myogenic pseudoobstruction disclosed by manometry. In another 4 patients, slow transit and pain prevailed in conjunction with normal manometric findings. Rapid transit and diarrhoea was found in 3 patients with various abberations on manometry. Of the remaining patients, 4 had slow transit and diarrhoea with intestinal neuropathy and pseudoobstruction, and 2 had slow transit along with endocrinopathies (diabetes, pituitary insufficiency).

Topics: Abdominal Pain; Adult; Aged; Breath Tests; Diarrhea; Female; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Intestinal Diseases; Intestinal Pseudo-Obstruction; Intestine, Small; Male; Manometry; Middle Aged; Radionuclide Imaging; Radiopharmaceuticals; Reference Values; Technetium Tc 99m Lidofenin

Technetium-99m dimethyl iminodiacetic acid cholescintigraphy has contributed significantly to the diagnosis of acute and chronic biliary tract disorders. Yet attention should also be focused on the other structures visualized during the blood pool, hepatocyte, renal excretory, and intestinal phases of the study. Nonbiliary pathology was detected in 42 of 294 patients (14.3%) studied for suspected acute cholecystitis. The serendipitous detection of previously unsuspected abnormalities assisted in directing further work-up from suspected biliary disease and towards the real source of the patient's acute problem in 28 cases (9.5%).

Topics: Acute Disease; Adult; Appendicitis; Cholecystitis; Diagnosis, Differential; Heart; Heart Diseases; Humans; Imino Acids; Intestinal Diseases; Intestines; Kidney; Kidney Diseases; Liver; Liver Diseases; Perfusion; Radionuclide Imaging; Technetium; Technetium Tc 99m Lidofenin