technetium-tc-99m-lidofenin and Gastritis

Topics: Bile Reflux; Duodenogastric Reflux; Gastric Emptying; Gastritis; Humans; Imino Acids; Organometallic Compounds; Peristalsis; Radionuclide Imaging; Technetium Tc 99m Lidofenin

Topics: Bile Reflux; Biliary Tract Diseases; Gastritis; Gastrointestinal Motility; Humans; Imino Acids; Postgastrectomy Syndromes; Technetium; Technetium Tc 99m Lidofenin

The authors comment the data from research on 70 patients with post cholecystectomy syndrome, using cholescintigraphy HIDA 99mTc to evaluate the relation ship between symptomatology (see classific.) and duodenogastric reflux entity. Cholescintigraphy seems to be a valid clinical means, especially for a correct indication to endoscopy.

Topics: Adult; Aged; Cholecystectomy; Diagnosis, Differential; Duodenogastric Reflux; Endoscopy; Female; Gallbladder; Gastritis; Humans; Imino Acids; Liver; Male; Middle Aged; Organotechnetium Compounds; Radionuclide Imaging; Syndrome; Technetium Tc 99m Lidofenin

The gastroduodenal reflux is considered, to be one of the important factors in the pathogenesis of gastritis and gastric ulcers. Endoscopic features suggesting bile reflux are not fully objective and may be a reason for false diagnosis of gastroduodenal reflux. The following study was established to verify the endoscopically diagnosed bile reflux by a scintigraphical test. In 30 of the 350 patients we showed bile reflux endoscopically, but 21 of them had duodenogastric reflux confirmed by cholescintigraphy. The autors maintain that cholescintigraphy seems to be a very useful method in the proper diagnosis of bile reflux.

Topics: Adolescent; Child; Duodenogastric Reflux; Female; Gastritis; Gastroscopy; Humans; Imino Acids; Male; Organotechnetium Compounds; Radionuclide Imaging; Technetium Tc 99m Lidofenin

Postoperative reflux gastritis in persons who were operated on for peptic ulcer occurs much more frequently after resection of the stomach (68.6%) than after organ-preserving operations on the stomach (39.4%). The incidence of reflux gastritis after gastric resection depends on the type of gastroenteroanastomosis. It is encountered much less frequently after Roux' operation (9.2%). The pronounced character and frequency of reflux gastritis after organ-preserving operations on the stomach are determined by the type of stomach-draining operations, the localization of the ulcer before the operation, whether in the stomach or the duodenum, the existence of duodenogastric reflux (DGR) before the operation. Measures for the prevention of postoperative reflux gastritis in the management of peptic ulcer are as follows: (a) wide introduction of organ-preserving operations, preferably SPV by itself or in combination with duodenoplasty; (b) formation of Roux' gastroenteroanastomosis when resection of the stomach is indicated. Reflux gastritis must be treated by nonoperative methods, including medicinal, dietetic, and spa therapy. Surgery is indicated in reflux gastritis combined with other diseases of a stomach which had been operated on, for which an operation is necessary, and in occasional cases of erosive reflux gastritis.

Topics: Aluminum Hydroxide; Anastomosis, Roux-en-Y; Antacids; Balneology; Benzocaine; Combined Modality Therapy; Drug Combinations; Duodenogastric Reflux; Duodenum; Gastrectomy; Gastritis; Gastroenterostomy; Humans; Imino Acids; Incidence; Magnesium Hydroxide; Metoclopramide; Organotechnetium Compounds; Peptic Ulcer; Postoperative Complications; Stomach; Technetium Tc 99m Lidofenin; Vagotomy, Proximal Gastric

In 28 controls and 142 patients subjected to a variety of antiulcer procedures, the enterogastric reflux (EGR) was quantitated by 99mTc-HIDA scintigraphy and expressed as the EGR index on 229 different occasions. The EGR index was calculated according to two different formulas: one based on the maximal radioactivity over the gastric area as a percentage value of the total abdominal activity (EGR-Im) and the other based on the relative maximal radioactivity over the gastric area as a percentage value of the relative hepatobiliary activity (EGR-It). There was a significant positive correlation of values between the two methods (P less than 0.0001). In patients with an EGR-Im greater than 20% or EGR-It greater than 57% and postgastric surgery symptoms some of the symptoms were attributed to EGR, an antireflux procedure is expected to relieve those symptoms. Sixteen of these patients underwent Roux-en-Y gastrectomy and their preoperative symptoms were relieved.

Topics: Duodenal Ulcer; Duodenogastric Reflux; Female; Gastritis; Humans; Imino Acids; Male; Middle Aged; Organotechnetium Compounds; Postgastrectomy Syndromes; Radionuclide Imaging; Stomach; Technetium Tc 99m Lidofenin; Vagotomy, Proximal Gastric; Vagotomy, Truncal

One hundred and seven patients with postoperative reflux gastritis treated by Roux-en-Y biliary diversion were reviewed. Three patients died in the postoperative period, and 16 others have since died; cardiorespiratory disease was the most frequent cause of death. Seventy-nine patients were interviewed at a median of 5.5 years (range 0.5-26 years) following Roux-en-Y diversion. At review, a satisfactory result by modified Visick grading was present in 47 per cent of patients. Bilious vomiting (P less than 0.001), food vomiting (P less than 0.01), the severity of upper abdominal pain (P less than 0.001) and heartburn (P less than 0.025) were significantly improved by Roux-en-Y diversion. Weight, haemoglobin levels and employment status were not significantly altered by the procedure. Outcome was related to the surgery preceding Roux-en-Y diversion with significantly better results after partial gastrectomy compared with truncal vagotomy and drainage (P less than 0.01), cholecystectomy (P less than 0.05), or combinations of these procedures (P less than 0.01). Outcome was not predicted by sex, preoperative symptoms, smoking status, consultant surgeon, length of Roux-en-Y or 99Tc-Sn-2,6-di-ethylacetanilidoiminodiacetate (HIDA) scanning results.

Topics: Adult; Aged; Anastomosis, Roux-en-Y; Female; Follow-Up Studies; Gastritis; Humans; Imino Acids; Male; Middle Aged; Organotechnetium Compounds; Postoperative Complications; Radionuclide Imaging; Technetium Tc 99m Lidofenin; Vomiting

We intended to estimate D.G.R. in patients suffering from GU, and CG, comparing them with healthy controls. 70 patients, divided in 3 groups, were studied; Group A (Control): 14 cases, Group B (GU) type I Johnson: 11 cases, type III Johnson: 20 cases; Group C (CG): 25 cases (11 antral and 14 antral and fundic). The following studies were performed in all of them upper digestive tract X-ray and fibro-endoscopy with multiple antral and fundic biopsies. Tc 99 HIDA 2 ml. Cu. I.V. was used as radioactive compound, and in the first hour 0.3 ml Cu. in 100 cc of water was administered orally, so as to confirm gastric topography. All patients were studied for 2 hour. Quantitative assessment of D.G.R. was expressed in % related to the hepatobiliary area. D.G.R. was detected in 7.1% of patients in Group A: 54.5% of GU type I and 70% in GU type III. In antral CG a 72.7% of D.G.R. was observed and in antral and fundic CG a 87.6% was found. The differences were significant in all the cases. D.G.R. MAGNITUDE, expressed as geometric mean, was: for Group A: 0.73%; for Group B: Ulcer type I: 6.26% and type III: 6.26%, for Group C: 6.78% in antral gastritis and 11.41% in antral and fundic gastritis.

Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Duodenogastric Reflux; Female; Gastritis; Humans; Imino Acids; Male; Middle Aged; Organometallic Compounds; Radionuclide Imaging; Stomach Ulcer; Technetium Tc 99m Lidofenin

The results of cholescintigraphy with 99mTc-HIDA in 245 children were analysed. The relationship of a latent time period with the state of the stomach-duodenum system was revealed. The specificity of this index was 82%, sensitivity 70%, accuracy 75% and pathology predictability 85%. The scintigraphic picture of a duodenobulbar reflux in the form of a RP "depot" in the ascending and upper horizontal part of the duodenum manifested itself with the specificity of 90% and predictability of pathology in 75%. Duodenogastric refluxes were revealed with the specificity of 94%, accuracy of 88% and pathology predictability of 90%. A low specificity of 34 and 43% was associated with a possibility of reflux detection in the lower horizontal part of the duodenum only.

Topics: Child; Duodenitis; Duodenogastric Reflux; Gastritis; Humans; Imino Acids; Radionuclide Imaging; Technetium; Technetium Tc 99m Lidofenin

Topics: Adolescent; Biliary Tract; Child; Duodenitis; Gastritis; Humans; Imino Acids; Liver; Technetium; Technetium Tc 99m Lidofenin; Tomography, Emission-Computed