technetium-tc-99m-lidofenin and Diarrhea

Symptoms from the gastro-intestinal tract are common and often difficult to evaluate. Specialised examination techniques are available only at a limited number of clinics. A technique based on biliary scintigraphy when measuring the transit of contents through the small intestine has been developed. The investigation is simple to perform and convenient for the patient. It can be carried out at any clinic equipped with a gamma camera. 30 healthy individuals were examined in order to obtain reference values. 23 patients were examined with scintigraphy in combination with upper gastrointestinal manometry, 10 of whom had abdominal pain and neurogenic or myogenic pseudoobstruction disclosed by manometry. In another 4 patients, slow transit and pain prevailed in conjunction with normal manometric findings. Rapid transit and diarrhoea was found in 3 patients with various abberations on manometry. Of the remaining patients, 4 had slow transit and diarrhoea with intestinal neuropathy and pseudoobstruction, and 2 had slow transit along with endocrinopathies (diabetes, pituitary insufficiency).

Topics: Abdominal Pain; Adult; Aged; Breath Tests; Diarrhea; Female; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Intestinal Diseases; Intestinal Pseudo-Obstruction; Intestine, Small; Male; Manometry; Middle Aged; Radionuclide Imaging; Radiopharmaceuticals; Reference Values; Technetium Tc 99m Lidofenin