technetium-tc-99m-lidofenin and Colonic-Neoplasms

Bronchobiliary fistula (BBF) represents a rare but severe complication in patients affected by liver metastases. Although a clinical suspicion can arise when specific clinical signs, in particular biliptysis, are present, conventional imaging modalities often fail to confirm the diagnosis. We present a case of a patient affected by colon cancer with liver metastases previously treated with partial right-sided hepatectomy and multiple thermo-ablative treatments combined with chemotherapy, who manifested a septic fever associated with productive cough and biliptysis. Diagnosis of BBF was confirmed only by hepatobiliary scintigraphy with (99m)Tc-heptoiminodiacetic acid.

Topics: Aged; Bile; Biliary Fistula; Bronchial Fistula; Cautery; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Colonic Neoplasms; Combined Modality Therapy; Drainage; Duodenum; Escherichia coli Infections; Female; Fever; Hepatectomy; Humans; Jaundice, Obstructive; Liver Neoplasms; Radionuclide Imaging; Stents; Technetium Tc 99m Lidofenin; Tomography, X-Ray Computed

16 patients with a history or suspicion of malignant disease were investigated scintigraphically for liver metastases. Each patient was studied with 99mTc-HIDA and 99mTc-sulphur- or tin-colloid. In 4 patients liver metastases were suspected and confirmed by ultrasonography and/or computerized tomography. The filling defects were visible with 99mTc-colloids and 99mTc-HIDA as well. Likewise both radiopharmaceuticals coincided in their parenchymal activity patterns in the nonsuspicious livers. Because of this good agreement the morphologic aspect of basically functional 99mTc-HIDA examinations is emphasized.

Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Hodgkin Disease; Humans; Imino Acids; Liver Neoplasms; Male; Middle Aged; Radionuclide Imaging; Skin Neoplasms; Technetium; Technetium Tc 99m Lidofenin; Teratoma; Testicular Neoplasms

Topics: Adult; Aged; Cholestasis, Extrahepatic; Colonic Neoplasms; False Positive Reactions; Female; Gallbladder Neoplasms; Humans; Imino Acids; Liver Neoplasms; Male; Middle Aged; Prostatic Neoplasms; Radionuclide Imaging; Sulfur; Technetium; Technetium Tc 99m Lidofenin; Technetium Tc 99m Sulfur Colloid