technetium-tc-99m-lidofenin and Bile-Duct-Diseases

Topics: Acute Disease; Adult; Bile Duct Diseases; Bile Ducts; Child; Cholecystitis; Cholecystokinin; Cholestasis, Extrahepatic; Cystic Duct; Humans; Imino Acids; Iodine Radioisotopes; Radionuclide Imaging; Rose Bengal; Technetium; Technetium Tc 99m Lidofenin

Topics: Ascites; Bile Duct Diseases; Bilirubin; Cholecystectomy; Cystic Duct; Drainage; Humans; Infant; Infant, Newborn; Male; Radiopharmaceuticals; Technetium Tc 99m Lidofenin; Ultrasonography

To assess the role of Tc-99m IDA cholescintigraphy in diagnosing bile leakage and bile obstruction after laparoscopic cholecystectomy, 51 studies were performed in 51 patients on the first postoperative day. Two different radioactive bile acid analogs were used, Tc-99m HIDA and Tc-99m trimethylbromo IDA. Scintigraphic findings were correlated with the clinical conditions. Results of seven out of 51 cholescintigrams were abnormal, showing accumulations of activity in the right paracolic gutter. Of these seven patients, only three had clinical symptoms consisting of more than normal postoperative abdominal pain and peritoneal irritation. The other four patients had minimal abnormal accumulation in the right paracolic gutter and showed no clinical signs postoperatively. Complete common bile duct obstruction or other bile duct-related complications, except for bile leakage, were not observed. Cholescintigraphy is feasible for the early detection of bile leakage and bile flow obstruction after laparoscopic cholecystectomy in patients with increased postoperative abdominal discomfort.

Topics: Bile Duct Diseases; Cholecystectomy; Cholestasis; Humans; Imino Acids; Laparoscopy; Organotechnetium Compounds; Postoperative Complications; Prospective Studies; Radionuclide Imaging; Technetium Tc 99m Lidofenin

Hepatic lithiasis is a major disease in Asia, especially East Asia. Its clinical aspect and incidence have been reviewed. The radionuclide methods ranging from sequential scintigraphy through hepatic retention ratio determination to retention ratio image would be simple and innocuous techniques for screening and detecting this disease.

Topics: Bile Duct Diseases; Cholangiography; Cholangitis; Cholelithiasis; Gallium Radioisotopes; Humans; Imino Acids; Organometallic Compounds; Radionuclide Imaging; Technetium Tc 99m Lidofenin

Topics: Adolescent; Bile Duct Diseases; Bile Ducts, Intrahepatic; Dilatation, Pathologic; Female; Humans; Imino Acids; Liver Abscess; Radionuclide Imaging; Technetium; Technetium Tc 99m Lidofenin

Two patients presenting with right upper abdominal colicky pain, jaundice, and fever had a hepatobiliary scan using Tc 99m HIDA. The scan was suggestive of acute cholecystitis and a space occupying lesion in the liver. On operation, liver echinococcosis, located in the right lobe rupturing into the biliary ductal system, was found. Intraoperative cholangiography revealed filling defects in the main biliary ducts. Exploration of the common bile duct disclosed daughter cysts and cystic debris. Acute cholecystitis or stones were not found. We conclude that in patients with a clinical picture and HIDA scanning compatible with acute cholecystitis and a space occupying lesion in the liver, the diagnosis of hydatid cyst of the liver which has ruptured into the biliary tract should be considered.

Topics: Acute Disease; Aged; Bile Duct Diseases; Bile Ducts; Cholecystitis; Diagnosis, Differential; Echinococcosis, Hepatic; Humans; Imino Acids; Liver; Male; Middle Aged; Radionuclide Imaging; Rupture, Spontaneous; Technetium; Technetium Tc 99m Lidofenin

Hepatobiliary scintigraphy with the 99mTc-labeled iminodiacetic acid derivatives has been shown to be useful in the evaluation of biliary tract diseases, especially for the diagnosis of acute cholecystitis. Little emphasis has been placed on the importance of the hepatic parenchymal image that occurs early in the imaging sequence. To determine what information can be obtained from the hepatic parenchymal image, a comparison was carried out of sulfur colloid and iminodiacetic acid images in 50 patients with focal defects. In 46 of 50 patients, the number and position of lesions on the two studies were similar, while in four patients the images were discordant. In addition to being very similar in lesion detection, the iminodiacetic acid scans also allowed more specificity in the later imaging (biliary phase) in 13 cases. The value of iminodiacetic acid derivatives in the evaluation of some biliary tract disorders has been established; considerable value can also be obtained by close inspection of the hepatic parenchymal image as well.

Topics: Adult; Bile Duct Diseases; Bile Ducts; Cholecystitis; Female; Humans; Imino Acids; Liver; Liver Neoplasms; Male; Middle Aged; Organotechnetium Compounds; Radionuclide Imaging; Sulfur; Technetium; Technetium Tc 99m Lidofenin; Technetium Tc 99m Sulfur Colloid; Time Factors

Three cases of choledochal cyst associated with intrahepatic biliary dilatation are presented. Findings on sonography included a large cystic mass in the porta hepatis separate from the gallbladder; a dilated common hepatic or common bile duct entering directly into the cyst; the smaller cystic masses of dilated central intrahepatic ducts. The dilatation of the central intrahepatic bile ducts was moderate in two patients and massive in one patient. All three patients underwent operation with intraoperative cholangiography. Two patients had 99mTc IDA cholescintigraphy which confirmed the diagnosis of choledochal cyst by demonstrating filling of the cyst with stasis and delayed intestinal activity. The accurate preoperative diagnosis of choledochal cyst, made by sonography combined with 99mTc IDA cholescintigraphy, obviated invasive studies.

Topics: Bile Duct Diseases; Bile Ducts, Intrahepatic; Child; Child, Preschool; Common Bile Duct Diseases; Cysts; Dilatation, Pathologic; Female; Humans; Imino Acids; Male; Organotechnetium Compounds; Radionuclide Imaging; Technetium; Technetium Tc 99m Lidofenin; Ultrasonography

Topics: Bile Duct Diseases; Bile Ducts, Intrahepatic; Computers; Humans; Imino Acids; Liver; Liver Diseases; Radionuclide Imaging; Subtraction Technique; Technetium; Technetium Tc 99m Lidofenin