technetium-tc-99m-gluconate and Kidney-Neoplasms

Combined use of 99mTc-diethylenetriaminepentaacetic acid (DTPA) radionuclide angiography, and 99mTc-gluconate renal venography plus single photo computed tomography (SPECT) were employed for clinical diagnosis of urinary tract tumor. This is what we call serial renal radionuclide imaging (SRI). From Aug, 1989 to May, 1993, 63 patients with urinary tract tumor accepted this examination, including 52 cases with renal space-occupying lesion, 5 cases with retroperitoneal mass outside of kidney, 4 cases with bladder cancer (all 61 cases were confirmed by surgery and pathology) and 2 cases suspected of anastomotic leakage after total cystectomy and Bricker's operation. The results show that 1. The renal space-occupying lesion could be accurately localized by SRI and benign lesions could be differentiated from malignancy. 2. SRI could asertain if a retroperitoneal mass was in or outside of the kidney. 3. Urinary fistula could be demonstrated by SRI, while IVU detection failed.

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Transitional Cell; Child; Gluconates; Humans; Kidney Neoplasms; Middle Aged; Organotechnetium Compounds; Radionuclide Angiography; Retroperitoneal Neoplasms; Technetium Tc 99m Pentetate; Tomography, Emission-Computed, Single-Photon; Urinary Bladder Neoplasms

In static scintigraphy with 99m Tc-pertechnetate of primary lesions of the retroperitoneal space in children 4 types of scintigraphic pictures were singled out for differential diagnosis of Wilms' tumors, avascular benign lesions of the retroperitoneal space and neurogenic retroperitoneal tumors. The sensitivity of diagnosis of Wilms' tumor was 92.6%, specificity 90.9%. The most objective and complete information on the kidney involvement in tumor process could be obtained in static scintigraphy with 99m Tc-pertechnetate combined with scintigraphy with 99m Tc-gluconate or 99m Tc-pyrophosphate. The sensitivity of diagnosis of secondary lesions of the lymph nodes of the retroperitoneal space was 76.8%.

Topics: Adolescent; Child; Child, Preschool; Diphosphates; Gluconates; Humans; Infant; Kidney Neoplasms; Organotechnetium Compounds; Radionuclide Imaging; Retroperitoneal Neoplasms; Sodium Pertechnetate Tc 99m; Technetium; Technetium Tc 99m Pyrophosphate; Wilms Tumor

Topics: Gluconates; Humans; Kidney; Kidney Diseases; Kidney Neoplasms; Organotechnetium Compounds; Radionuclide Imaging; Renal Circulation; Technetium