technetium-tc-99m-gluceptate and Multiple-Sclerosis

Cerebral computed tomography, with and without iodinated contrast, revealed the appearance and evolution of lesions in a 32-year-old man with multiple sclerosis. Two areas were enhanced with contrast, with one showing a mild mass effect and rim of enhancement. Serial brain scintigraphy using technetium-99m glucoheptonate, following the computed tomography, showed the appearance and regression of corresponding regions of increased uptake. Computed tomography one day prior to brain scintigraphy failed to demonstrate a region of increased accumulation of radiotracer. One week later, however, evidence of a corresponding unenhanced defect was noted on computed tomography. Clinical correlation is given additionally.

Topics: Adult; Brain; Humans; Male; Multiple Sclerosis; Organotechnetium Compounds; Radiographic Image Enhancement; Radionuclide Imaging; Sugar Acids; Technetium; Tomography, X-Ray Computed