technetium-tc-99m-exametazime and Mycoses

Imaging findings from a single case of disseminated infection with Fusarium are presented. This common fungus has been reported as a rare pathogen to the immunocompromised. Disseminated foci were identified on a Tc-99m HMPAO labeled WBC study. Two foci were localized to the proximal tibia using MRI. In this case, imaging was more sensitive to the extent of disease than physical examination, and it also provided a more precise estimate of disease progression than clinical evaluation alone. Imaging offers potential to track regression and to identify early recurrence. This is especially valuable because infection with Fusarium tends to be indolent.

Topics: Adult; Fusarium; Humans; Immunocompromised Host; Leukocytes; Magnetic Resonance Imaging; Male; Mycoses; Organotechnetium Compounds; Oximes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radionuclide Imaging; Sensitivity and Specificity; Technetium Tc 99m Exametazime; Tibia