technetium-tc-99m-exametazime and Lyme-Disease

SPECT imaging brain perfusion using 99mTc-HMPAO was performed on a 38-yr-old women with Lyme neuroborreliosis confirmed by autopsy. The patient had been suspected of spinocerebellar degeneration. Cerebral blood flow was diffusely decreased throughout cerebral cortices but cerebellar blood flow was not impaired, which indicated that the diagnosis was unlikely spinocerebellar degeneration. These findings suggested that brain perfusion SPECT provides useful information in diagnosing the patients with Lyme neuroborreliosis, especially when spinocerebellar degeneration is included in the differential diagnosis.

Topics: Adult; Brain; Central Nervous System Diseases; Cerebrovascular Circulation; Diagnosis, Differential; Female; Humans; Lyme Disease; Organotechnetium Compounds; Oximes; Radiopharmaceuticals; Spinocerebellar Degenerations; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon