technetium-tc-99m-exametazime and Drug-Overdose

technetium-tc-99m-exametazime has been researched along with Drug-Overdose* in 1 studies

Other Studies

1 other study(ies) available for technetium-tc-99m-exametazime and Drug-Overdose

ArticleYear
Long lasting impaired cerebral blood flow after ecstasy intoxication.
    Psychiatry and clinical neurosciences, 2003, Volume: 57, Issue:2

    Four hours after having taken 10 ecstasy tablets a Grand Mal seizure occurred in a 19-year-old woman followed by coma, hyperthermia, tachycardia, tachypnea, and renal failure. After awakening she was oriented but presented with helplessness, disconcertion, hallucinations, panic attacks, and amnesic syndrome. Computed tomography and magnetic resonance imaging scans of the brain were normal. [99Tc]-hexamethylpropyleneamine oxime (HMPAO)-single photon emission computed tomography (SPECT), 20 days after intoxication, showed reduced, inhomogeneous, supratentorial tracer uptake bilaterally. Electroencephalography (EEG) disclosed diffuse slowing and occasionally generalized sharp waves. Valproic acid was begun. Except for slight amnesia, neuropsychological deficits had disappeared and [99Tc]-HMPAO-SPECT normalized, 29 days later. Decreased cortical blood flow was explained by vasoconstriction following ecstasy-induced depletion of serotonin.

    Topics: Adult; Brain Ischemia; Cerebral Cortex; Coma; Dominance, Cerebral; Drug Overdose; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Neuropsychological Tests; Regional Blood Flow; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon; Vasoconstriction

2003