technetium-tc-99m-bicisate and Psychotic-Disorders

Topics: Anticonvulsants; Brain; Child; Cysteine; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Male; Neurologic Examination; Organotechnetium Compounds; Psychotic Disorders; Radiopharmaceuticals; Status Epilepticus; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

Postictal psychoses are brief psychotic episodes that usually occur after poorly controlled partial complex seizure clusters. The psychosis commonly appears following a lucid interval, ranging from a few hours to days after seizure termination. An underlying structural brain abnormality is common and usually involves the temporal lobe. Postictal psychosis, while well known in adults, has not been described previously in children. We describe a 9-year-old boy with right hemiparesis due to a neonatal stroke, who developed a postictal schizophrenia-like psychosis following status epilepticus. Electroencephalography showed left-sided slowing. A brain computed tomographic scan and magnetic resonance imaging revealed left hemisphere hypoplasia. A 99mTc-ECD single photon emission computed tomographic scan of the brain revealed decreased left-hemisphere perfusion, most pronounced to the medial temporal lobe. The psychosis resolved gradually over 7 days without antipsychotic therapy. To the best of our knowledge, this is the first description of postictal psychosis in a child.

Topics: Child; Cysteine; Electroencephalography; Functional Laterality; Humans; Male; Organotechnetium Compounds; Psychotic Disorders; Radiopharmaceuticals; Status Epilepticus; Tomography, Emission-Computed