technetium-tc-99m-bicisate has been researched along with Calcinosis* in 2 studies
2 other study(ies) available for technetium-tc-99m-bicisate and Calcinosis
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Imaging of bilateral striopallidodentate calcinosis.
Bilateral symmetric striopallidodentate calcinosis, also known as Fahr's disease, is characterized by bilateral calcifications of the basal ganglia, thalami, dentate nuclei of the cerebellum, and the white matter of the cerebral hemisphere. Intracranial calcifications are easily visible as high-density areas on computed tomographic images. On magnetic resonance images, the calcifications exhibit different signal intensities. The differences in signal intensity are thought to be related to the stage of the disease, differences in calcium metabolism, and the volume of the calcium deposit. The moderate reduction of cerebral blood flow in bilateral thalami was also identified using brain SPECT. Topics: Aged; Basal Ganglia Diseases; Brain Diseases; Calcinosis; Cerebellar Diseases; Cysteine; Dysarthria; Gait Ataxia; Humans; Male; Occipital Lobe; Organotechnetium Compounds; Paralysis; Radiography; Radiopharmaceuticals; Thalamic Diseases; Tomography, Emission-Computed, Single-Photon | 2002 |
Cerebral perfusion abnormalities in therapy-resistant epilepsy in childhood: comparison between EEG, MRI and 99Tcm-ECD brain SPET.
We performed 99Tcm-ethyl cysteinate dimer (ECD) interictal single photon emission tomography (SPET) in 26 children with severe therapy-resistant epilepsy. All the children underwent a detailed clinical examination, an electroencephalogram (EEG) investigation and brain magnetic resonance imaging (MRI). In 21 of the 26 children, SPET demonstrated brain blood flow abnormalities, in 13 cases in the same territories that showed EEG alterations. MRI showed structural lesions in 6 of the 26 children, while SPET imaging confirmed these abnormalities in only 5 children. The lesion not detected on SPET was shown to be 3 mm thick on MRI. Five symptomatic patients had normal SPET. In one of these patients, the EEG findings were normal and MRI revealed a small calcific nodule (4 mm thick); in the others, the EEG showed non-focal but diffuse abnormalities. These data confirm that brain SPET is sensitive in detecting and localizing hypoperfused areas that could be associated with epileptic foci in this group of patients, even when the MRI image is normal. Topics: Adolescent; Brain; Calcinosis; Child; Child, Preschool; Cysteine; Electroencephalography; Epilepsy; Female; Humans; Infant; Magnetic Resonance Imaging; Male; Organotechnetium Compounds; Tomography, Emission-Computed, Single-Photon | 1996 |