td-5108 has been researched along with Heart-Defects--Congenital* in 1 studies
1 other study(ies) available for td-5108 and Heart-Defects--Congenital
| Article | Year |
|---|---|
Functional activity of 5-HT4 receptors in children with congenital heart disease.
The effect of 5-methoxytryptamine (5-HT(4) receptor agonist) on the inotropic function of atrial myocardium was studied in children aged 2 months to 17 years, operated on for congenital heart disease. Functional activity of 5-HT(4) receptors was 8.4 times higher in dysfunction of the atrial septum in comparison with other congenital heart diseases. The positive inotropic effects of 5-HT(4) receptor agonist can promote compensation of myocardial work in children with pathological circulation. Topics: 5-Methoxytryptamine; Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Heart Atria; Heart Defects, Congenital; Heart Septal Defects, Atrial; Humans; Infant; Myocardium; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists | 2006 |