td-5108 has been researched along with Depressive-Disorder--Major* in 1 studies
1 other study(ies) available for td-5108 and Depressive-Disorder--Major
Article | Year |
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CK2 regulates 5-HT4 receptor signaling and modulates depressive-like behavior.
The serotonergic neurotransmitter system has been widely implicated in the pathophysiology of mood-related disorders such as anxiety and major depressive disorder (MDD). The onset of therapeutic efficacy of traditional antidepressants is delayed by several weeks. The 5-HT Topics: Animals; Antidepressive Agents; Anxiety; Brain; Casein Kinase II; Corpus Striatum; Depression; Depressive Disorder, Major; Hippocampus; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prefrontal Cortex; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Signal Transduction; Sulfonamides | 2018 |