Page last updated: 2024-09-05

tbc-11251 and Proteinuria

tbc-11251 has been researched along with Proteinuria in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chariyavilaskul, P; Corder, R; Dhaun, N; Goddard, J; Kimmitt, RA; MacIntyre, IM; Webb, DJ; Wood, EG; Yuzugulen, J1
Cheung, L; Cosgrove, D; Delimont, D; Dufek, B; Gratton, MA; Liu, S; Meehan, DT; Phillips, G; Song, W1
Bellamy, CO; Dhaun, N; Kluth, DC; MacIntyre, IM1
Angelini, GD; George, SJ; Jones, C; Lin, H; Murphy, GJ; Patel, NN; Ray, P; Satchell, SC; Sleeman, P; Toth, T; Welsh, G1
Dhaun, N; Goddard, J; Haughie, S; Johnston, NR; Kerr, D; MacIntyre, IM; Melville, V; Webb, DJ1
Barton, M1
Dhaun, N; Goddard, J; MacDougall, M; Melville, V; Towler, JD; Webb, DJ1
Blackwell, S; Dhaun, N; Goddard, J; Johnston, NR; Melville, V; Talwar, DK; Webb, DJ1

Reviews

1 review(s) available for tbc-11251 and Proteinuria

ArticleYear
Endothelin antagonism and reversal of proteinuric renal disease in humans.
    Contributions to nephrology, 2011, Volume: 172

    Topics: Endothelins; Humans; Isoxazoles; Kidney Diseases; Phenylpropionates; Proteinuria; Pyridines; Pyrimidines; Receptor, Endothelin A; Thiophenes

2011

Trials

4 trial(s) available for tbc-11251 and Proteinuria

ArticleYear
Plasma pro-endothelin-1 peptide concentrations rise in chronic kidney disease and following selective endothelin A receptor antagonism.
    Journal of the American Heart Association, 2015, Mar-23, Volume: 4, Issue:3

    Topics: Adult; Biomarkers; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Endothelin A Receptor Antagonists; Endothelin-1; Female; Humans; Isoxazoles; Male; Middle Aged; Nifedipine; Protein Precursors; Proteinuria; Receptor, Endothelin A; Renal Insufficiency, Chronic; Scotland; Thiophenes; Time Factors; Treatment Outcome; Up-Regulation; Vascular Stiffness

2015
Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:4

    Topics: Adult; Antihypertensive Agents; Arteries; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Endothelin A Receptor Antagonists; Female; Glomerular Filtration Rate; Humans; Hypertension; Isoxazoles; Kidney Failure, Chronic; Male; Middle Aged; Nifedipine; Proteinuria; Radioimmunoassay; Thiophenes; Treatment Outcome; Vascular Resistance; Vasodilator Agents

2011
What is the best method of proteinuria measurement in clinical trials of endothelin receptor antagonists?
    Life sciences, 2012, Oct-15, Volume: 91, Issue:13-14

    Topics: Albuminuria; Analysis of Variance; Creatinine; Double-Blind Method; Drug Monitoring; Endothelin Receptor Antagonists; Humans; Isoxazoles; Proteinuria; Renal Insufficiency, Chronic; Reproducibility of Results; Thiophenes

2012
Endothelin-A receptor antagonism modifies cardiovascular risk factors in CKD.
    Journal of the American Society of Nephrology : JASN, 2013, Volume: 24, Issue:1

    Topics: Adult; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cross-Over Studies; Double-Blind Method; Endothelin Receptor Antagonists; Endothelin-1; Female; Humans; Isoxazoles; Male; Middle Aged; Nifedipine; Proteinuria; Pulse Wave Analysis; Renal Insufficiency, Chronic; Thiophenes; Vascular Stiffness; Vasodilator Agents

2013

Other Studies

3 other study(ies) available for tbc-11251 and Proteinuria

ArticleYear
Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease.
    Kidney international, 2016, Volume: 90, Issue:2

    Topics: Animals; Biomechanical Phenomena; Disease Models, Animal; Endothelial Cells; Endothelin Receptor Antagonists; Endothelin-1; Fluorescent Antibody Technique; Gene Knockdown Techniques; Glomerular Basement Membrane; Hypertension; Isoxazoles; Laminin; Mesangial Cells; Mice; Mice, Inbred C57BL; Nephritis, Hereditary; Podocytes; Proteinuria; Pseudopodia; Receptor, Endothelin A; RNA Interference; RNA, Small Interfering; Signal Transduction; Thiophenes; Up-Regulation

2016
Endothelin receptor antagonism and renin inhibition as treatment options for scleroderma kidney.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:4

    Topics: Amides; Antihypertensive Agents; Atrophy; Biomarkers; Biopsy; Endothelin Receptor Antagonists; Female; Fibrosis; Fumarates; Humans; Hypertension, Renal; Isoxazoles; Kidney; Middle Aged; Proteinuria; Pulmonary Fibrosis; Renal Insufficiency, Chronic; Renin; Scleroderma, Systemic; Thiophenes; Treatment Outcome

2009
Prevention of post-cardiopulmonary bypass acute kidney injury by endothelin A receptor blockade.
    Critical care medicine, 2011, Volume: 39, Issue:4

    Topics: Acute Kidney Injury; Animals; Cardiopulmonary Bypass; Creatinine; Endothelin A Receptor Antagonists; Endothelium, Vascular; Female; Interleukin-18; Isoxazoles; Proteinuria; Renal Circulation; Swine; Thiophenes

2011