Page last updated: 2024-09-03

tazobactam and Critical Illness

tazobactam has been researched along with Critical Illness in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	24 (63.16)	24.3611
2020's	14 (36.84)	2.80

Authors

Authors	Studies
Abdul-Aziz, MH; Burrows, F; Buscher, H; Cheng, V; Cho, YJ; Corley, A; Diehl, A; Fraser, JF; Gilder, E; Jakob, SM; Kim, HS; Levkovich, BJ; Lim, SY; McGuinness, S; Parke, R; Pellegrino, V; Que, YA; Reynolds, C; Roberts, JA; Rudham, S; Shekar, K; Wallis, SC; Welch, SA; Zacharias, D	1
Burgess, DS; Clark, JA; Landmesser, KB	1
Kim, HI; Kim, HS; Kim, YK; Lee, DH; Lee, SH; Park, S	1
Akers, KS; Chung, KK; DeLuca, JP; Livezey, JR; Nadeau, RJ; Por, ED; Pruskowski, KA; Selig, DJ	1
Babiak, P; Cizmarova, I; Kovac, A; Mikus, P; Parrak, V; Piestansky, J; Secnik, P	1
Ankravs, MJ; Bellomo, R; Deane, AM; Rechnitzer, T; Roberts, JA; Sharrock, L; Wallis, SC	1
Laramie, KE; Miller, MA; Mueller, SW; Roper, SE; Torian, SC; Wiktor, AJ	1
Enache Leonte, G; Ghiciuc, CM; Luca, CM; Onofrei, MI; Postolache, P; Rosu, FM; Sapaniuc, C	1
Lassig-Smith, M; Lipman, J; Pandey, S; Parker, SL; Roberts, JA; Sime, FB; Starr, T; Stuart, J; Wallis, SC	1
Barreto Gutierrez, L; De Bels, D; Gallerani, A; Honore, PM; Kaefer, K; Mugisha, A; Redant, S	1
Aso, S; Fushimi, K; Goto, H; Kaita, Y; Kojiro, M; Matsui, H; Nakajima, M; Yamaguchi, Y; Yasunaga, H	1
Adedoyin, A; Caro, L; De Waele, JJ; Gadzicki, E; Kuti, JL; Larson, KB; Nicolau, DP; Rhee, EG; Yu, B; Zeng, Z	1
Concordet, D; Delmas, C; Gandia, P; Georges, B; Jourdan, G; Mané, C; Marcheix, B; Porterie, J; Ruiz, S; Verwaerde, P	1
De Ponti, F; Gatti, M; Giannella, M; Raschi, E; Viale, P	1
Asensio-Martín, MJ; Balandin, B; Ballesteros, D; Chicot, M; Fernández-Simón, I; Iranzo, R; López-Vergara, L; Martínez-Sagasti, F; Pérez-Pedrero, MJ; Pintado, V; Rodríguez-Serrano, D; Royuela, A; Ruiz de Luna, R; Sancho-González, M; Silva, A; Soriano-Cuesta, C	1
Collings, H; Dillon, R; Enstone, A; Palmer, T; Puzniak, L	1
Caissy, JA; El-Haffaf, I; Marsot, A	1
Carlier, M; De Cock, PAJG; de Jaeger, A; De Paepe, P; Delanghe, JR; Della Pasqua, OE; Robays, H; van Dijkman, SC; Vande Walle, J; Verstraete, AG; Willems, J	1
Aubron, C; Corallo, C	1
Bennis, Y; Bodeau, S; Kontar, L; Lemaire-Hurtel, AS; Maizel, J; Masmoudi, K; Quinton, MC; Slama, M; Zerbib, Y	1
Mueller, BA; Shaw, AR	1
Borgia, G; Cascella, M; Corcione, S; Cuomo, A; De Rosa, FG; Gentile, I; Maraolo, AE; Nappa, S	1
Guerra Valero, YC; Lipman, J; Naicker, S; Ordenez Meija, JL; Parker, SL; Roberts, JA; Wallis, SC	1
Beckman, EJ	1
Lipman, J; Peake, SL; Roberts, JA; Roberts, MS; Sinnollareddy, MG	1
Alobaid, A; Hiremath, S; Kanji, S; Patel, R; Porteous, R; Roberts, JA; Watpool, I; Xie, J; Zelenitsky, S; Zhang, G	1
Benaboud, S; Béranger, A; Bille, E; Gana, I; Genuini, M; Hirt, D; Lesage, F; Moulin, F; Oualha, M; Renolleau, S; Tréluyer, JM; Urien, S; Zheng, Y	1
Farkas, A; Heil, EL; Nicolau, DP; Roberts, JA; Thom, KA	1
Blevins, AM; Juang, P; Kollef, M; Lashinsky, JN; McCammon, C; Micek, S	1
Aguilar, G; Alós, M; Carbonell, JA; Ezquer, C; Ferriols, R; Martínez-Castro, S; Navarro, D; Pastor, E	1
Althaus, K; Busemann, C; Friesecke, S; Greinacher, A; Hron, G; Knutson, F; Lubenow, N; Thiele, T	1
Boots, RJ; Jarrett, P; Kirkpatrick, CM; Lipman, J; Roberts, JA; Varghese, JM	1
Akers, KS; Cannon, JW; Chung, KK; Cota, JM; Murray, CK; Niece, KL	1
Bentley, AM; Felton, TW; Goodwin, J; Hope, WW; Isalska, B; Malagon, I; McCalman, K; Whalley, S	1
Gonzales, JP; Heil, EL; Mehrotra, S; Nicolau, DP; Oliver, WD; Robinett, K; Saleeb, P	1
Ghazi, IM; Kuti, JL; Nicolau, DP; Quintiliani, R; Shore, E	1
Blondiaux, N; Courcol, RJ; Durocher, A; Favory, R; Nseir, S; Onimus, T; Roussel-Delvallez, M; Wallet, F	1
Bellomo, R; Cole, L; Lipman, J; Liu, X; Nair, P; Roberts, DM; Roberts, JA; Roberts, MS	1

Reviews

6 review(s) available for tazobactam and Critical Illness

Article	Year
Pharmacokinetics of piperacillin and tazobactam in critically Ill patients treated with continuous kidney replacement therapy: A mini-review and population pharmacokinetic analysis. Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:8 Topics: Anti-Bacterial Agents; Critical Illness; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Replacement Therapy; Tazobactam	2022
Optimization of Therapy and the Risk of Probiotic Use during Antibiotherapy in Septic Critically Ill Patients: A Narrative Review. Medicina (Kaunas, Lithuania), 2023, Feb-28, Volume: 59, Issue:3 Topics: Adolescent; Anti-Bacterial Agents; Critical Illness; Humans; Piperacillin, Tazobactam Drug Combination; Tazobactam	2023
Real-world use of ceftolozane/tazobactam: a systematic literature review. Antimicrobial resistance and infection control, 2021, 04-08, Volume: 10, Issue:1 Topics: Cephalosporins; Comorbidity; Critical Illness; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacterial Infections; Humans; Intraabdominal Infections; Pseudomonas Infections; Respiratory Tract Infections; Tazobactam; Urinary Tract Infections	2021
Piperacillin-Tazobactam in Intensive Care Units: A Review of Population Pharmacokinetic Analyses. Clinical pharmacokinetics, 2021, Volume: 60, Issue:7 Topics: Anti-Bacterial Agents; Critical Illness; Humans; Intensive Care Units; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Prospective Studies; Tazobactam	2021
Antibiotic Dosing in Continuous Renal Replacement Therapy. Advances in chronic kidney disease, 2017, Volume: 24, Issue:4 Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Computer Simulation; Critical Illness; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Renal Replacement Therapy; Sepsis; Tazobactam; Thienamycins	2017
Management of multidrug-resistant Pseudomonas aeruginosa in the intensive care unit: state of the art. Expert review of anti-infective therapy, 2017, Volume: 15, Issue:9 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Ceftazidime; Cephalosporins; Critical Illness; Disease Management; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Intensive Care Units; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Factors; Tazobactam; Treatment Outcome	2017

Trials

2 trial(s) available for tazobactam and Critical Illness

Article	Year
Lung penetration, bronchopulmonary pharmacokinetic/pharmacodynamic profile and safety of 3 g of ceftolozane/tazobactam administered to ventilated, critically ill patients with pneumonia. The Journal of antimicrobial chemotherapy, 2020, 06-01, Volume: 75, Issue:6 Topics: Anti-Bacterial Agents; Cephalosporins; Critical Illness; Humans; Lung; Pneumonia; Tazobactam	2020
Pulmonary penetration of piperacillin and tazobactam in critically ill patients. Clinical pharmacology and therapeutics, 2014, Volume: 96, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Critical Illness; Drug Combinations; Drug Resistance, Bacterial; Female; Humans; Lung; Male; Middle Aged; Monte Carlo Method; Penicillanic Acid; Permeability; Piperacillin; Tazobactam	2014

Other Studies

30 other study(ies) available for tazobactam and Critical Illness

Article	Year
Population Pharmacokinetics of Piperacillin and Tazobactam in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation: an ASAP ECMO Study. Antimicrobial agents and chemotherapy, 2021, 10-18, Volume: 65, Issue:11 Topics: Anti-Bacterial Agents; Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Piperacillin; Tazobactam	2021
Time Above All Else: Pharmacodynamic Analysis of β-Lactams in Critically Ill Patients. Journal of clinical pharmacology, 2022, Volume: 62, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Critical Illness; Humans; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Piperacillin; Pseudomonas aeruginosa; Tazobactam	2022
Population pharmacokinetics of piperacillin/tazobactam in critically ill Korean patients and the effects of extracorporeal membrane oxygenation. The Journal of antimicrobial chemotherapy, 2022, 04-27, Volume: 77, Issue:5 Topics: Adult; Anti-Bacterial Agents; Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Republic of Korea; Tazobactam	2022
An Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Determination of 4 β-Lactam Antibiotics, Tazobactam, and Linezolid in Human Plasma Samples. Therapeutic drug monitoring, 2022, 12-01, Volume: 44, Issue:6 Topics: Anti-Bacterial Agents; Cefepime; Cefotaxime; Chromatography, High Pressure Liquid; Critical Illness; Drug Monitoring; Humans; Linezolid; Meropenem; Monobactams; Piperacillin; Reproducibility of Results; Tandem Mass Spectrometry; Tazobactam	2022
Clearance of Piperacillin-Tazobactam and Vancomycin During Continuous Renal Replacement With Regional Citrate Anticoagulation. Therapeutic drug monitoring, 2023, 04-01, Volume: 45, Issue:2 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Anticoagulants; Citrates; Citric Acid; Critical Illness; Humans; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam; Vancomycin	2023
Burn Injury and Augmented Renal Clearance: A Case for Optimized Piperacillin-Tazobactam Dosing. Journal of burn care & research : official publication of the American Burn Association, 2023, 01-05, Volume: 44, Issue:1 Topics: Anti-Bacterial Agents; Burns; Critical Illness; Humans; Microbial Sensitivity Tests; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2023
A Population Pharmacokinetic Model-Guided Evaluation of Ceftolozane-Tazobactam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration. Antimicrobial agents and chemotherapy, 2019, 12-20, Volume: 64, Issue:1 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cephalosporins; Confidence Intervals; Continuous Renal Replacement Therapy; Critical Illness; Hemodiafiltration; Humans; Microbial Sensitivity Tests; Prospective Studies; Pseudomonas aeruginosa; Tazobactam	2019
Optimizing ceftolozane-tazobactam dosage during continuous renal replacement therapy: additional insights. Critical care (London, England), 2019, 12-12, Volume: 23, Issue:1 Topics: Cephalosporins; Continuous Renal Replacement Therapy; Critical Illness; Humans; Tazobactam	2019
Effect of high-dose vitamin C therapy on severe burn patients: a nationwide cohort study. Critical care (London, England), 2019, 12-12, Volume: 23, Issue:1 Topics: Adult; Ascorbic Acid; Burns; Cephalosporins; Cohort Studies; Continuous Renal Replacement Therapy; Critical Illness; Humans; Tazobactam	2019
Influence of extracorporeal membrane oxygenation on the pharmacokinetics of ceftolozane/tazobactam: an ex vivo and in vivo study. Journal of translational medicine, 2020, 05-27, Volume: 18, Issue:1 Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Swine; Tazobactam	2020
Ceftolozane/tazobactam exposure in critically ill patients undergoing continuous renal replacement therapy: a PK/PD approach to tailor dosing. The Journal of antimicrobial chemotherapy, 2021, 01-01, Volume: 76, Issue:1 Topics: Anti-Bacterial Agents; Cephalosporins; Continuous Renal Replacement Therapy; Critical Illness; Humans; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Pseudomonas aeruginosa; Renal Replacement Therapy; Tazobactam	2021
Multicenter study of ceftolozane/tazobactam for treatment of Pseudomonas aeruginosa infections in critically ill patients. International journal of antimicrobial agents, 2021, Volume: 57, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cephalosporins; Critical Illness; Cross Infection; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Female; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Spain; Tazobactam; Treatment Outcome	2021
Dose optimization of piperacillin/tazobactam in critically ill children. The Journal of antimicrobial chemotherapy, 2017, 07-01, Volume: 72, Issue:7 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Tazobactam	2017
β-Lactams Dosing in Overweight Critically Ill Patients: Are We Driving in the Dark? Critical care medicine, 2017, Volume: 45, Issue:5 Topics: beta-Lactams; Critical Illness; Humans; Obesity; Overweight; Tazobactam	2017
Neurotoxic Concentration of Piperacillin during Continuous Infusion in Critically Ill Patients. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:9 Topics: Aged; Anti-Bacterial Agents; Critical Care; Critical Illness; Drug Monitoring; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nervous System Diseases; Penicillanic Acid; Piperacillin; Retrospective Studies; Tazobactam	2017
A UHPLC-MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of pharmaceutical and biomedical analysis, 2018, Jan-30, Volume: 148 Topics: Calibration; Chromatography, High Pressure Liquid; Critical Illness; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Plasma; Renal Replacement Therapy; Sensitivity and Specificity; Tandem Mass Spectrometry; Tazobactam; Urine	2018
Piperacillin-Tazobactam Plus Vancomycin Equals Acute Kidney Injury: Does It Add Up? Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2017, Volume: 18, Issue:12 Topics: Acute Kidney Injury; Child; Critical Illness; Humans; Piperacillin; Tazobactam; Vancomycin	2017
Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. The Journal of antimicrobial chemotherapy, 2018, 06-01, Volume: 73, Issue:6 Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Critical Illness; Female; Filtration; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Piperacillin; Prospective Studies; Renal Dialysis; Renal Replacement Therapy; Tazobactam	2018
Piperacillin Population Pharmacokinetics in Critically Ill Adults During Sustained Low-Efficiency Dialysis. The Annals of pharmacotherapy, 2018, Volume: 52, Issue:10 Topics: Adult; Aged; Anti-Bacterial Agents; Critical Illness; Female; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Renal Dialysis; Renal Replacement Therapy; Tazobactam	2018
Piperacillin Population Pharmacokinetics and Dosing Regimen Optimization in Critically Ill Children with Normal and Augmented Renal Clearance. Clinical pharmacokinetics, 2019, Volume: 58, Issue:2 Topics: Adolescent; Anti-Bacterial Agents; Bacteria; Child; Child, Preschool; Critical Illness; Female; Humans; Infant; Kidney; Male; Microbial Sensitivity Tests; Models, Biological; Piperacillin; Tazobactam	2019
Pharmacodynamic Target Attainment for Cefepime, Meropenem, and Piperacillin-Tazobactam Using a Pharmacokinetic/Pharmacodynamic-Based Dosing Calculator in Critically Ill Patients. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:9 Topics: Anti-Bacterial Agents; Cefepime; Critical Illness; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Tazobactam	2018
Incidence of Acute Kidney Injury in Critically Ill Patients Receiving Vancomycin with Concomitant Piperacillin-Tazobactam, Cefepime, or Meropenem. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:5 Topics: Acute Kidney Injury; Aged; Cefepime; Critical Illness; Female; Humans; Incidence; Male; Meropenem; Middle Aged; Multivariate Analysis; Piperacillin; Retrospective Studies; Tazobactam; Vancomycin	2019
Optimizing ceftolozane-tazobactam dosage in critically ill patients during continuous venovenous hemodiafiltration. Critical care (London, England), 2019, 04-26, Volume: 23, Issue:1 Topics: Aged; Anti-Bacterial Agents; Cephalosporins; Critical Illness; Dose-Response Relationship, Drug; Hemofiltration; Humans; Male; Tazobactam	2019
Alternative diagnosis to heparin-induced thrombocytopenia in two critically ill patients despite a positive PF4/heparin-antibody test. Upsala journal of medical sciences, 2013, Volume: 118, Issue:4 Topics: Aged; Critical Illness; Diagnosis, Differential; Enzyme-Linked Immunosorbent Assay; Femoral Neck Fractures; Heparin; Humans; Methotrexate; Pancytopenia; Penicillanic Acid; Piperacillin; Platelet Count; Platelet Factor 4; Purpura, Thrombocytopenic; Tazobactam; Thrombocytopenia; Transfusion Reaction	2013
Pharmacokinetics of piperacillin and tazobactam in plasma and subcutaneous interstitial fluid in critically ill patients receiving continuous venovenous haemodiafiltration. International journal of antimicrobial agents, 2014, Volume: 43, Issue:4 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Critical Illness; Extracellular Fluid; Female; Half-Life; Hemofiltration; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Prospective Studies; Sepsis; Tazobactam	2014
Modified Augmented Renal Clearance score predicts rapid piperacillin and tazobactam clearance in critically ill surgery and trauma patients. The journal of trauma and acute care surgery, 2014, Volume: 77, Issue:3 Suppl 2 Topics: Adult; Aged, 80 and over; Anti-Bacterial Agents; Creatinine; Critical Illness; Cross-Sectional Studies; Female; Humans; Kidney Diseases; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Tazobactam; Wounds and Injuries; Young Adult	2014
Ceftolozane-Tazobactam Pharmacokinetics in a Critically Ill Patient on Continuous Venovenous Hemofiltration. Antimicrobial agents and chemotherapy, 2015, Dec-28, Volume: 60, Issue:3 Topics: Anti-Bacterial Agents; Cephalosporins; Critical Illness; Drug Resistance, Multiple, Bacterial; Hemofiltration; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Prospective Studies; Prosthesis-Related Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2015
Treatment of multidrug-resistant Pseudomonas aeruginosa with ceftolozane/tazobactam in a critically ill patient receiving continuous venovenous haemodiafiltration. International journal of antimicrobial agents, 2016, Volume: 48, Issue:3 Topics: Aged; Anti-Infective Agents, Urinary; beta-Lactamase Inhibitors; Cephalosporins; Chromatography, High Pressure Liquid; Critical Illness; Drug Resistance, Multiple, Bacterial; Hemofiltration; Humans; Male; Penicillanic Acid; Plasma; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Treatment Outcome; United States	2016
Daily serum piperacillin monitoring is advisable in critically ill patients. International journal of antimicrobial agents, 2010, Volume: 35, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Critical Illness; Drug Monitoring; Female; France; Hospitals, Teaching; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Penicillanic Acid; Piperacillin; Prospective Studies; Serum; Tazobactam; Time Factors	2010
Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: a multicentre pharmacokinetic study. Critical care medicine, 2012, Volume: 40, Issue:5 Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Ciprofloxacin; Critical Illness; Female; Hemofiltration; Humans; Male; Meropenem; Middle Aged; Penicillanic Acid; Piperacillin; Tazobactam; Thienamycins; Vancomycin	2012