Page last updated: 2024-11-04

tazarotene and Nail Diseases

tazarotene has been researched along with Nail Diseases in 14 studies

tazarotene: a topical acetylenic retinoid; a topical kerytolytic
tazarotene : The ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin.

Nail Diseases: Diseases of the nail plate and tissues surrounding it. The concept is limited to primates.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy and safety of FCL plus topical tazarotene versus tazarotene monotherapy in the treatment of nail psoriasis."9.51Efficacy of combined fractional carbon dioxide laser and topical tazarotene in nail psoriasis treatment: A randomized intrapatient left-to-right study. ( Essa Abd Elazim, N; Mahmoud Abdelsalam, A; Mohamed Awad, S, 2022)
"Tazarotene is a topically-applied, receptor-selective retinoid that has been shown to modulate several major pathogenic factors of psoriasis."7.80Periungual pyogenic granulomas due to topical tazarotene for nail psoriasis. ( Patrizi, A; Piraccini, BM; Venturi, M, 2014)
"Our study shows the therapeutic potential of tazarotene ointment in nail psoriasis."7.78Nail psoriasis: treatment with tazarotene 0.1% hydrophilic ointment. ( Collgros, H; Expósito-Serrano, V; Fischer-Levancini, C; Llambí, F; Sánchez-Regaña, M; Umbert-Millet, P, 2012)
"The tazarotene treatment resulted in a significantly greater reduction in onycholysis in occluded nails (P < or = ."6.70Tazarotene 0.1% gel in the treatment of fingernail psoriasis: a double-blind, randomized, vehicle-controlled study. ( Scher, RK; Stiller, M; Zhu, YI, 2001)
"To evaluate the efficacy and safety of FCL plus topical tazarotene versus tazarotene monotherapy in the treatment of nail psoriasis."5.51Efficacy of combined fractional carbon dioxide laser and topical tazarotene in nail psoriasis treatment: A randomized intrapatient left-to-right study. ( Essa Abd Elazim, N; Mahmoud Abdelsalam, A; Mohamed Awad, S, 2022)
"Tazarotene is a topically-applied, receptor-selective retinoid that has been shown to modulate several major pathogenic factors of psoriasis."3.80Periungual pyogenic granulomas due to topical tazarotene for nail psoriasis. ( Patrizi, A; Piraccini, BM; Venturi, M, 2014)
"Our study shows the therapeutic potential of tazarotene ointment in nail psoriasis."3.78Nail psoriasis: treatment with tazarotene 0.1% hydrophilic ointment. ( Collgros, H; Expósito-Serrano, V; Fischer-Levancini, C; Llambí, F; Sánchez-Regaña, M; Umbert-Millet, P, 2012)
"Nail psoriasis is difficult to treat."2.78Efficacy of pulsed dye laser plus topical tazarotene versus topical tazarotene alone in psoriatic nail disease: a single-blind, intrapatient left-to-right controlled study. ( Chiang, YY; Chou, CL; Huang, YC, 2013)
"The tazarotene treatment resulted in a significantly greater reduction in onycholysis in occluded nails (P < or = ."2.70Tazarotene 0.1% gel in the treatment of fingernail psoriasis: a double-blind, randomized, vehicle-controlled study. ( Scher, RK; Stiller, M; Zhu, YI, 2001)
"Psoriasis is a chronic skin disease that affects millions of people throughout the world."2.44Psoriasis of the nail: anatomy, pathology, clinical presentation, and a review of the literature on therapy. ( Jiaravuthisan, MM; Muhn, CY; Murphy, F; Sasseville, D; Vender, RB, 2007)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (64.29)29.6817
2010's4 (28.57)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Essa Abd Elazim, N1
Mahmoud Abdelsalam, A1
Mohamed Awad, S1
Huang, YC1
Chou, CL1
Chiang, YY1
Piraccini, BM1
Venturi, M1
Patrizi, A1
Sherber, NS1
Hoch, AM1
Coppola, CA1
Carter, EL1
Chang, HL1
Barsanti, FR1
Mackay-Wiggan, JM1
Fischer-Levancini, C1
Sánchez-Regaña, M1
Llambí, F1
Collgros, H1
Expósito-Serrano, V1
Umbert-Millet, P1
Kroiss, MM1
Vogt, T1
Finkenzeller, T1
Landthaler, M1
Stolz, W1
Bianchi, L2
Soda, R2
Diluvio, L2
Chimenti, S3
Hagman, JH1
Ginebri, A1
Mordenti, C1
De Simoni, I1
Rigopoulos, D1
Gregoriou, S1
Katsambas, A1
Prevost, NM1
English, JC1
Waller, JM1
Wu, JJ1
Murase, JE1
Dyson, SW1
Kelly, KM1
Jiaravuthisan, MM1
Sasseville, D1
Vender, RB1
Murphy, F1
Muhn, CY1
Scher, RK1
Stiller, M1
Zhu, YI1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Combined Fractional Carbon Dioxide Laser and Topical Tazarotene in the Treatment of Psoriatic: Nail Disease a Single-blind, Intrapatient Left-to-right Controlled Study.[NCT03263624]Phase 430 participants (Anticipated)Interventional2017-10-01Not yet recruiting
Subclinical Nail Involvement in Relevant Skin Diseases[NCT04092413]384 participants (Anticipated)Observational2019-11-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for tazarotene and Nail Diseases

ArticleYear
Psoriasis of the nail: anatomy, pathology, clinical presentation, and a review of the literature on therapy.
    Journal of the American Academy of Dermatology, 2007, Volume: 57, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Clinical Trials as Topic; Cyclosporine;

2007
Psoriasis of the nail: anatomy, pathology, clinical presentation, and a review of the literature on therapy.
    Journal of the American Academy of Dermatology, 2007, Volume: 57, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Clinical Trials as Topic; Cyclosporine;

2007
Psoriasis of the nail: anatomy, pathology, clinical presentation, and a review of the literature on therapy.
    Journal of the American Academy of Dermatology, 2007, Volume: 57, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Clinical Trials as Topic; Cyclosporine;

2007
Psoriasis of the nail: anatomy, pathology, clinical presentation, and a review of the literature on therapy.
    Journal of the American Academy of Dermatology, 2007, Volume: 57, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Clinical Trials as Topic; Cyclosporine;

2007

Trials

5 trials available for tazarotene and Nail Diseases

ArticleYear
Efficacy of combined fractional carbon dioxide laser and topical tazarotene in nail psoriasis treatment: A randomized intrapatient left-to-right study.
    Journal of cosmetic dermatology, 2022, Volume: 21, Issue:7

    Topics: Dermatologic Agents; Humans; Lasers, Gas; Nail Diseases; Nicotinic Acids; Psoriasis; Treatment Outco

2022
Efficacy of pulsed dye laser plus topical tazarotene versus topical tazarotene alone in psoriatic nail disease: a single-blind, intrapatient left-to-right controlled study.
    Lasers in surgery and medicine, 2013, Volume: 45, Issue:2

    Topics: Administration, Topical; Adult; Aged; Combined Modality Therapy; Dermatologic Agents; Drug Administr

2013
Tazarotene 0.1% gel for psoriasis of the fingernails and toenails: an open, prospective study.
    The British journal of dermatology, 2003, Volume: 149, Issue:1

    Topics: Adult; Aged; Dermatologic Agents; Female; Humans; Male; Middle Aged; Nail Diseases; Nicotinic Acids;

2003
Treatment of psoriatic nails with tazarotene cream 0.1% vs. clobetasol propionate 0.05% cream: a double-blind study.
    Acta dermato-venereologica, 2007, Volume: 87, Issue:2

    Topics: Administration, Topical; Clobetasol; Dermatologic Agents; Double-Blind Method; Humans; Keratolytic A

2007
Tazarotene 0.1% gel in the treatment of fingernail psoriasis: a double-blind, randomized, vehicle-controlled study.
    Cutis, 2001, Volume: 68, Issue:5

    Topics: Adult; Dermatologic Agents; Double-Blind Method; Drug Evaluation; Female; Fingers; Gels; Humans; Mal

2001

Other Studies

8 other studies available for tazarotene and Nail Diseases

ArticleYear
Periungual pyogenic granulomas due to topical tazarotene for nail psoriasis.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2014, Volume: 149, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Dermatologic Agents; Female; Granuloma, Pyogenic; Humans; Ma

2014
Efficacy and safety study of tazarotene cream 0.1% for the treatment of brittle nail syndrome.
    Cutis, 2011, Volume: 87, Issue:2

    Topics: Administration, Topical; Aged; Female; Humans; Keratolytic Agents; Male; Middle Aged; Nail Diseases;

2011
Nail psoriasis: treatment with tazarotene 0.1% hydrophilic ointment.
    Actas dermo-sifiliograficas, 2012, Volume: 103, Issue:8

    Topics: Dermatologic Agents; Humans; Nail Diseases; Nicotinic Acids; Ointments; Psoriasis

2012
[Psoriatic onycho-pachydermo- periostitis].
    Zeitschrift fur Rheumatologie, 2002, Volume: 61, Issue:5

    Topics: Adult; Antirheumatic Agents; Arthritis, Psoriatic; Diagnosis, Differential; Drug Therapy, Combinatio

2002
Treatment of occupational koilonychia with tazarotene gel.
    Acta dermato-venereologica, 2003, Volume: 83, Issue:4

    Topics: Administration, Cutaneous; Construction Materials; Dermatitis, Occupational; Dermatologic Agents; Ge

2003
Treatment of trachyonychia with tazarotene.
    Clinical and experimental dermatology, 2005, Volume: 30, Issue:3

    Topics: Adult; Alopecia Areata; Humans; Keratolytic Agents; Male; Nail Diseases; Nicotinic Acids

2005
Palliative treatment of fingernail lichen planus.
    Journal of drugs in dermatology : JDD, 2007, Volume: 6, Issue:2

    Topics: Administration, Topical; Aged; Clobetasol; Drug Therapy, Combination; Female; Gels; Humans; Lichen P

2007
Chronically painful right thumb with pustules and onycholysis. Diagnosis: acrodermatitis continua of Hallopeau.
    Clinical and experimental dermatology, 2007, Volume: 32, Issue:5

    Topics: Acrodermatitis; Aged; Chronic Disease; Dermatologic Agents; Diagnosis, Differential; Female; Humans;

2007