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tazarotene and Hypermelanosis

tazarotene has been researched along with Hypermelanosis in 9 studies

tazarotene: a topical acetylenic retinoid; a topical kerytolytic
tazarotene : The ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin.

Research Excerpts

ExcerptRelevanceReference
"Patients with facial mottled hyperpigmentation of at least moderate severity and an overall integrated assessment of photodamage score of at least moderate applied tazarotene 0."5.12Tazarotene versus tazarotene plus hydroquinone in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized study. ( Draelos, Z; Horwitz, S; Lowe, N; Menter, A; Tanghetti, E, 2006)
" All significant between-group differences in efficacy measures were in favor of tazarotene - for fine wrinkling at the study endpoint and, at earlier timepoints, for treatment success (> or =50% global improvement), and the overall integrated assessment of photodamage, mottled hyperpigmentation, and coarse wrinkling."5.11Tazarotene 0.1% cream versus tretinoin 0.05% emollient cream in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized, parallel-group study. ( Gifford, M; Goldman, M; Kang, S; Lowe, N; Poulin, Y; Rosenzweig, H; Tanghetti, E; Tse, Y; Yamauchi, P, 2004)
"In this multicentre, double-blind, randomized, vehicle-controlled study, 50 patients with photodamaged facial skin (at least mild fine wrinkling and mottled hyperpigmentation, with at least one of these being moderate) were randomized to apply tazarotene 0."5.11Histological effects of tazarotene 0.1% cream vs. vehicle on photodamaged skin: a 6-month, multicentre, double-blind, randomized, vehicle-controlled study in patients with photodamaged facial skin. ( Holland, JM; Kaidbey, K; Lim, J; Loven, KH; Machtinger, LA; Parizadeh, DD; Rist, TE; Sefton, J; Walker, PS; Wilson, DC, 2004)
"A total of 568 patients with at least moderate fine wrinkling or mottled hyperpigmentation applied tazarotene 0."5.11A multicenter, randomized, double-blind trial of tazarotene 0.1% cream in the treatment of photodamage. ( Gibson, JR; Kang, S; Krueger, GG; Lew-Kaya, D; Sefton, J; Tanghetti, EA; Walker, PS, 2005)
"Tazarotene cream and tretinoin cream significantly improved mottled hyperpigmentation and fine wrinkles."5.09Tazarotene cream for the treatment of facial photodamage: a multicenter, investigator-masked, randomized, vehicle-controlled, parallel comparison of 0.01%, 0.025%, 0.05%, and 0.1% tazarotene creams with 0.05% tretinoin emollient cream applied once daily f ( Bhawan, J; Gibson, JR; Kang, S; Lew-Kaya, DA; Leyden, JJ; Lowe, NJ; Matsumoto, RM; Ortonne, JP; Phillips, TJ; Sefton, J; Walker, PS; Weinstein, GD, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (77.78)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gleghorn, K1
Riddle, T1
Subrt, A1
Kelly, E1
Tanghetti, E3
Dhawan, S1
Green, L1
Del Rosso, J1
Draelos, Z2
Leyden, J1
Shalita, A1
Glaser, DA1
Grimes, P2
Webster, G1
Barnett, P1
Le Gall, N1
Lowe, N2
Gifford, M1
Poulin, Y1
Goldman, M1
Tse, Y1
Yamauchi, P1
Rosenzweig, H1
Kang, S3
Machtinger, LA1
Kaidbey, K1
Lim, J1
Loven, KH1
Rist, TE1
Wilson, DC1
Parizadeh, DD1
Sefton, J3
Holland, JM1
Walker, PS3
Krueger, GG1
Tanghetti, EA1
Lew-Kaya, D1
Gibson, JR2
Callender, V1
Horwitz, S1
Menter, A1
Saks, K1
Levitt, JO1
Leyden, JJ1
Lowe, NJ1
Ortonne, JP1
Phillips, TJ1
Weinstein, GD1
Bhawan, J1
Lew-Kaya, DA1
Matsumoto, RM1

Trials

7 trials available for tazarotene and Hypermelanosis

ArticleYear
Randomized comparison of the safety and efficacy of tazarotene 0.1% cream and adapalene 0.3% gel in the treatment of patients with at least moderate facial acne vulgaris.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:5

    Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Adolescent; Adult; Child; Dermatologic Agents;

2010
Tazarotene 0.1% cream versus tretinoin 0.05% emollient cream in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized, parallel-group study.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2004, Volume: 6, Issue:2

    Topics: Administration, Topical; Dermatologic Agents; Double-Blind Method; Emollients; Face; Female; Humans;

2004
Histological effects of tazarotene 0.1% cream vs. vehicle on photodamaged skin: a 6-month, multicentre, double-blind, randomized, vehicle-controlled study in patients with photodamaged facial skin.
    The British journal of dermatology, 2004, Volume: 151, Issue:6

    Topics: Adult; Aged; Double-Blind Method; Facial Dermatoses; Female; Humans; Hyperpigmentation; Keratinocyte

2004
A multicenter, randomized, double-blind trial of tazarotene 0.1% cream in the treatment of photodamage.
    Journal of the American Academy of Dermatology, 2005, Volume: 52, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Dermatologic Agents; Double-Blind Method; Facial Dermatoses; Female;

2005
Tazarotene cream for postinflammatory hyperpigmentation and acne vulgaris in darker skin: a double-blind, randomized, vehicle-controlled study.
    Cutis, 2006, Volume: 77, Issue:1

    Topics: Acne Vulgaris; Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Child; Dermato

2006
Tazarotene versus tazarotene plus hydroquinone in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized study.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2006, Volume: 8, Issue:3

    Topics: Administration, Topical; Chi-Square Distribution; Dermatologic Agents; Double-Blind Method; Female;

2006
Tazarotene cream for the treatment of facial photodamage: a multicenter, investigator-masked, randomized, vehicle-controlled, parallel comparison of 0.01%, 0.025%, 0.05%, and 0.1% tazarotene creams with 0.05% tretinoin emollient cream applied once daily f
    Archives of dermatology, 2001, Volume: 137, Issue:12

    Topics: Administration, Cutaneous; Adult; Dermatologic Agents; Dose-Response Relationship, Drug; Double-Blin

2001

Other Studies

2 other studies available for tazarotene and Hypermelanosis

ArticleYear
Postinflammatory hyperpigmentation following treatment of hyperkeratosis lenticularis perstans with tazarotene cream 0.1.
    Cutis, 2019, Volume: 104, Issue:2

    Topics: Dermatologic Agents; Female; Humans; Hyperpigmentation; Keratosis; Middle Aged; Nicotinic Acids

2019
Tazarotene 0.1 percent cream fares better than erbium:YAG laser or incision and drainage in a patient with eruptive vellus hair cysts.
    Dermatology online journal, 2006, Oct-31, Volume: 12, Issue:6

    Topics: Child; Cysts; Dermatologic Agents; Drug Evaluation; Female; Hair Follicle; Humans; Hyperpigmentation

2006