taxane and Sex-Cord-Gonadal-Stromal-Tumors

taxane has been researched along with Sex-Cord-Gonadal-Stromal-Tumors* in 1 studies

Other Studies

1 other study(ies) available for taxane and Sex-Cord-Gonadal-Stromal-Tumors

ArticleYear
Impact of taxane plus bevacizumab for ovarian sex cord tumor with annular tubules.
    The journal of obstetrics and gynaecology research, 2019, Volume: 45, Issue:7

    Sex cord tumor with annular tubules (SCTAT) is rare, and 20% of SCTAT cases, excluding those associated with Peutz-Jeghers syndrome, are clinically malignant. Limited data is available regarding the role of chemotherapy in the management of SCTAT. We encountered a 44-year-old woman with recurrent SCTAT complicated by peritoneal dissemination following a right adnexectomy. The surgical resection could not be performed completely due to the wide extension of the tumor. Considering the potential of becoming malignant, we chose a combination of bleomycin, etoposide and cisplatin (BEP) as postoperative chemotherapy treatment. However, the patient showed partial response following a complete BEP regimen. The patient received three courses of chemotherapy with docetaxel and carboplatin plus bevacizumab. After the combination chemotherapy, positron emission tomography-computed tomography scan confirmed a complete response, and is currently continuing bevacizumab treatment without relapsing and having no major adverse effects from complications. This case proved the potential of a combination of taxane and bevacizumab in patients with recurrent SCTAT.

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bridged-Ring Compounds; Female; Humans; Ovarian Neoplasms; Ovary; Sex Cord-Gonadal Stromal Tumors; Taxoids

2019