tauromuricholate and Colorectal-Neoplasms

tauromuricholate has been researched along with Colorectal-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for tauromuricholate and Colorectal-Neoplasms

ArticleYear
FXR Regulates Intestinal Cancer Stem Cell Proliferation.
    Cell, 2019, 02-21, Volume: 176, Issue:5

    Increased levels of intestinal bile acids (BAs) are a risk factor for colorectal cancer (CRC). Here, we show that the convergence of dietary factors (high-fat diet) and dysregulated WNT signaling (APC mutation) alters BA profiles to drive malignant transformations in Lgr5-expressing (Lgr5

    Topics: Animals; Bile Acids and Salts; Cell Line; Cell Proliferation; Colorectal Neoplasms; Deoxycholic Acid; Gene Expression Regulation, Neoplastic; Humans; Intestinal Neoplasms; Intestines; Liver; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells; Organoids; Receptors, Cytoplasmic and Nuclear; Risk Factors; Signal Transduction; Taurocholic Acid; Wnt Signaling Pathway

2019