taurocholic acid has been researched along with Cholestasis, Intrahepatic in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.12) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 11 (33.33) | 29.6817 |
| 2010's | 13 (39.39) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Funk, C; Gasser, R; Jehle, L; Lazendic, M; Pantze, M; Ponelle, C; Scheuermann, G | 1 |
| Chen, M; Chen, Z; Dong, R; Li, N; Luo, L; Wang, J; Wang, T; Wang, Y; Zhang, T; Zhang, Y; Zhou, C; Zhou, T; Zou, P; Zou, S | 1 |
| Alahakoon, TI; Curnow, J; George, J; Heath, S; Lin, MW; Smet, ME; Wu, C | 1 |
| Chiba, P; Schmid, D; Sohail, MI; Spork, M; Stockner, T; Szakács, G; Trauner, M; Wlcek, K | 1 |
| Ballauff, A; Burdelski, M; Dröge, C; Ellinger, P; Häussinger, D; Herebian, D; Kluge, S; Kubitz, R; Mayatepek, E; Sattler, K; Schmitt, L; Schulte Am Esch, J; Schulz-Jürgensen, S; Smits, SHJ; Stindt, J; Stross, C | 1 |
| Du, Q; Mao, X; Ni, X; Qin, X; Ying, H | 1 |
| Arase, Y; Hirose, S; Kagawa, T; Mine, T; Mizutani, A; Orii, R; Shiraishi, K; Tsukamoto, H | 1 |
| Chen, D; Cheng, J; Luo, L; Wang, T; Xiang, J; Zhang, T; Zhao, C | 1 |
| de Waart, DR; Ho-Mok, KS; Knisely, AS; Oude Elferink, RP; Paulusma, CC; Tabbers, MM; van der Mark, VA; Voogt, HW | 1 |
| Barabanchyk, OV; Kozak, NP; Svintsits'kyĭ, AS | 1 |
| Gooijert, KE; Havinga, R; Ling, V; Tazuma, S; Verkade, HJ; Wang, R; Wolters, H | 1 |
| Burban, A; Burbank, MG; Guguen-Guillouzo, C; Guillouzo, A; Sharanek, A; Weaver, RJ | 1 |
| Bridle, KR; Doecke, JD; Greco, SA; Hoskins, AC; Lewindon, PJ; Meikle, PJ; Ney, AD; Pereira, TN; Ramm, GA; Shepherd, RW; Turlin, B | 1 |
| Ansede, JH; Brouwer, KR; Perry, CH; Smith, WR; St Claire, RL | 1 |
| Jemnitz, K; Vereczkey, L; Veres, Z | 1 |
| Bhakoo, K; Bowman, N; Brown, L; Chambers, J; Dixon, PH; Geenes, VL; Lim, YH; Tailor, H; Williamson, C; Wyatt-Ashmead, J | 1 |
| de Bruin, J; Elling, G; Faber, KN; Geuken, M; Heegsma, J; Jansen, PL; Mol, O; Müller, M; Plass, JR | 1 |
| Arias, IM; Dawson, PA; Harris, MJ; Kagawa, T | 1 |
| Iwanaga, T; Maeda, T; Nakakariya, M; Tamai, I; Yabuuchi, H | 1 |
| Agellon, LB; Bull, LN; Groen, A; Kramer, W; Kunne, C; Oude Elferink, RP; Paulusma, CC | 1 |
| Hayashi, H; Sugiyama, Y | 1 |
| Arias, IM; Ikeno, Y; Itoh, J; Kagawa, T; Mine, T; Mochizuki, K; Numari, A; Tanaka, H; Watanabe, N | 1 |
| Konno, Y; Nakagawa, M; Tada, K; Tazawa, Y; Yamada, M | 1 |
| Goldsmith, MA; Huling, S; Jones, AL | 1 |
| Höke, H; Krell, H; Pfaff, E | 1 |
| Kakis, G; Yousef, IM | 1 |
| Ando, M; Fukumoto, Y; Okita, K; Okuda, M; Yasunaga, M | 1 |
| Buscher, HP; Gerok, W; MacNelly, S; Meder, I | 1 |
| Andrejko, KM; Chen, J; Deutschman, CS; Kim, PK | 1 |
| Fattinger, K; Funk, C; Meier, PJ; Pantze, M; Reichen, J; Stieger, B; Weber, C | 1 |
| Ballatori, N; Boyer, JL; Cai, SY; Wang, L | 1 |
| Joseph, LD; Plaa, GL; Sharkawi, M; Yousef, IM | 1 |
| Fromm, H; Krell, H; Larson, RE | 1 |
33 other study(ies) available for taurocholic acid and Cholestasis, Intrahepatic
| Article | Year |
|---|---|
Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biliary Tract; Biological Transport, Active; Cholestasis, Intrahepatic; Chromans; Cytosol; Female; Glyburide; Hypoglycemic Agents; Liver; Male; Rats; Rats, Wistar; Sex Factors; Sulfates; Taurocholic Acid; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
ERp29 inhibition attenuates TCA toxicity via affecting p38/p53- dependent pathway in human trophoblast HTR-8/SVeno cells.
Topics: Apoptosis; Cell Line; Cholestasis, Intrahepatic; Female; G2 Phase Cell Cycle Checkpoints; Gene Knockdown Techniques; Heat-Shock Proteins; Humans; M Phase Cell Cycle Checkpoints; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Pregnancy Complications; Taurocholic Acid; Trophoblasts; Tumor Suppressor Protein p53 | 2019 |
Pregnancy complicated by refractory severe hypercholanaemia from sodium taurocholate co-transporting polypeptide deficiency.
Topics: Bile Acids and Salts; Cholestasis, Intrahepatic; Female; Humans; Infant, Newborn; Peptides; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Taurocholic Acid; Ursodeoxycholic Acid | 2021 |
Molecular Mechanism of Taurocholate Transport by the Bile Salt Export Pump, an ABC Transporter Associated with Intrahepatic Cholestasis.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Binding Sites; Biological Transport; Cholestasis, Intrahepatic; HEK293 Cells; Humans; Protein Structure, Secondary; Protein Structure, Tertiary; Taurocholic Acid | 2017 |
Partial external biliary diversion in bile salt export pump deficiency: Association between outcome and mutation.
Topics: Adolescent; ATP Binding Cassette Transporter, Subfamily B, Member 11; Bile Acids and Salts; Biliary Tract Surgical Procedures; Biological Transport; Biopsy; Cholestasis, Intrahepatic; Chromatography, High Pressure Liquid; Female; HEK293 Cells; Humans; Infant; Liver; Liver Transplantation; Male; Mutagenesis; Mutation, Missense; Recombinant Proteins; Sequence Analysis, DNA; Substrate Specificity; Tandem Mass Spectrometry; Taurochenodeoxycholic Acid; Taurocholic Acid; Transfection; Treatment Outcome | 2017 |
Cholestatic pregnancy is associated with reduced VCAM1 expression in vascular endothelial cell of placenta.
Topics: Apoptosis; Cell Line; Cell Proliferation; Cell Survival; Cholestasis, Intrahepatic; Endothelial Cells; Female; Humans; MicroRNAs; Placenta; Pregnancy; Pregnancy Complications; RNA, Messenger; Taurocholic Acid; Vascular Cell Adhesion Molecule-1 | 2017 |
Ursodeoxycholic acid stabilizes the bile salt export pump in the apical membrane in MDCK II cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Cell Membrane; Cholestasis, Intrahepatic; Dogs; Endocytosis; Hepatocytes; Madin Darby Canine Kidney Cells; Mutation; Rats; Taurocholic Acid; Ursodeoxycholic Acid | 2014 |
High concentraction of taurocholic acid induced apoptosis in HTR-8/SVneo cells via overexpression of ERp29 and activation of p38.
Topics: Apoptosis; Caspase 3; Cell Cycle; Cell Line; Cholestasis, Intrahepatic; Enzyme Activation; Female; Gene Expression; Heat-Shock Proteins; Humans; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Placenta; Pregnancy; Pregnancy Complications; RNA, Small Interfering; Taurocholic Acid; Trophoblasts | 2014 |
The lipid flippase heterodimer ATP8B1-CDC50A is essential for surface expression of the apical sodium-dependent bile acid transporter (SLC10A2/ASBT) in intestinal Caco-2 cells.
Topics: Adenosine Triphosphatases; Bile Acids and Salts; Biological Transport; Blotting, Western; Caco-2 Cells; Cell Membrane; Cholestasis, Intrahepatic; Feces; Humans; Intestinal Mucosa; Membrane Proteins; Mutation; Organic Anion Transporters, Sodium-Dependent; Protein Multimerization; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Symporters; Taurocholic Acid | 2014 |
[CORRECTION OF BILE FLOW CHARACTERISTICS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE IN COMBINATION WITH HYPERURICEMIA].
Topics: Adult; Allopurinol; Bile; Cholagogues and Choleretics; Cholestasis, Intrahepatic; Cholesterol; Cholic Acid; Deoxycholic Acid; Drug Therapy, Combination; Duodenoscopy; Female; Fluorobenzenes; Humans; Hyperuricemia; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Taurocholic Acid; Uric Acid; Ursodeoxycholic Acid | 2014 |
The mechanism of increased biliary lipid secretion in mice with genetic inactivation of bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Bile Canaliculi; Cholestasis, Intrahepatic; Female; Lipoproteins; Male; Mice; Mice, Inbred C57BL; Phospholipids; RNA, Messenger; Taurocholic Acid | 2015 |
Early Alterations of Bile Canaliculi Dynamics and the Rho Kinase/Myosin Light Chain Kinase Pathway Are Characteristics of Drug-Induced Intrahepatic Cholestasis.
Topics: Amides; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Carrier Proteins; Cell Line; Cholestasis, Intrahepatic; Humans; Liver; Membrane Glycoproteins; Multidrug Resistance-Associated Proteins; Myosin-Light-Chain Kinase; Pyridines; rho-Associated Kinases; Signal Transduction; Taurocholic Acid | 2016 |
Fibrogenesis in pediatric cholestatic liver disease: role of taurocholate and hepatocyte-derived monocyte chemotaxis protein-1 in hepatic stellate cell recruitment.
Topics: Animals; Biopsy; Cell Movement; Chemokine CCL2; Child; Child, Preschool; Cholestasis, Intrahepatic; Cystic Fibrosis; DNA Primers; Hepatic Stellate Cells; Hepatocytes; Humans; Liver; Rats; Reverse Transcriptase Polymerase Chain Reaction; Taurocholic Acid | 2009 |
An in vitro assay to assess transporter-based cholestatic hepatotoxicity using sandwich-cultured rat hepatocytes.
Topics: Algorithms; Animals; Bile; Bile Acids and Salts; Biological Transport; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Chromatography, High Pressure Liquid; Collagen; Culture Techniques; Dose-Response Relationship, Drug; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Hepatocytes; Laminin; Male; Proteoglycans; Rats; Rats, Wistar; Tandem Mass Spectrometry; Taurocholic Acid; Toxicity Tests | 2010 |
Contribution of high basolateral bile salt efflux to the lack of hepatotoxicity in rat in response to drugs inducing cholestasis in human.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis, Intrahepatic; Chromans; Humans; Hypoglycemic Agents; Male; Organic Anion Transporters, Sodium-Dependent; Rats; Rats, Wistar; Species Specificity; Symporters; Taurocholic Acid; Thiazolidinediones; Troglitazone | 2010 |
A placental phenotype for intrahepatic cholestasis of pregnancy.
Topics: Cholestasis, Intrahepatic; Female; Humans; Phenotype; Placenta; Pregnancy; Pregnancy Complications; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 2011 |
A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Canaliculi; Cell Line, Tumor; Cholestasis, Intrahepatic; Disease Progression; Drug Stability; Glycine; Glycosylation; Green Fluorescent Proteins; Humans; Indicators and Reagents; Luminescent Proteins; Mice; Molecular Sequence Data; Mutation, Missense; Protein Transport; Recombinant Fusion Proteins; Taurocholic Acid; Temperature | 2004 |
Taurocholate transport by hepatic and intestinal bile acid transporters is independent of FIC1 overexpression in Madin-Darby canine kidney cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport, Active; Blotting, Western; Cell Culture Techniques; Cholestasis, Intrahepatic; Dogs; Gene Expression Regulation; Kidney; Organic Anion Transporters, Sodium-Dependent; Symporters; Taurocholic Acid | 2004 |
Involvement of bile salt export pump in flutamide-induced cholestatic hepatitis.
Topics: Androgen Antagonists; Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cells, Cultured; Cholestasis, Intrahepatic; Dose-Response Relationship, Drug; Flutamide; Inhibitory Concentration 50; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spodoptera; Taurocholic Acid; Transport Vesicles | 2007 |
Intestinal bile salt absorption in Atp8b1 deficient mice.
Topics: Adenosine Triphosphatases; Animals; Bile Acids and Salts; Cholates; Cholestasis, Intrahepatic; Diet; Disease Models, Animal; DNA-Binding Proteins; Fibroblast Growth Factors; Gene Expression; Intestinal Absorption; Mice; Mice, Knockout; Organic Anion Transporters, Sodium-Dependent; Perfusion; Phospholipid Transfer Proteins; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Symporters; Taurocholic Acid; Transcription Factors | 2007 |
4-phenylbutyrate enhances the cell surface expression and the transport capacity of wild-type and mutated bile salt export pumps.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Canaliculi; Biological Transport; Cells, Cultured; Cholestasis, Intrahepatic; Dogs; Humans; Kidney; Male; Membrane Proteins; Mutation; Phenylbutyrates; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Transcription, Genetic; Tritium; Up-Regulation | 2007 |
Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells.
Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Cell Line; Cholestasis; Cholestasis, Intrahepatic; Dogs; Genotype; Half-Life; Models, Molecular; Molecular Sequence Data; Mutation; Phenotype; Protein Conformation; Protein Transport; Rats; RNA, Messenger; Taurocholic Acid; Time Factors; Transfection | 2008 |
Unconjugated, glycine-conjugated, taurine-conjugated bile acid nonsulfates and sulfates in urine of young infants with cholestasis.
Topics: Bile Acids and Salts; Bile Ducts; Cholestasis, Intrahepatic; Chromatography, High Pressure Liquid; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Infant; Infant, Newborn; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1984 |
Hepatic handling of bile salts and protein in the rat during intrahepatic cholestasis.
Topics: Animals; Autoradiography; Bile Acids and Salts; Biological Transport, Active; Cholestasis, Intrahepatic; Endoplasmic Reticulum; Ethinyl Estradiol; Glycocholic Acid; Golgi Apparatus; Histamine; Horseradish Peroxidase; Iodine Radioisotopes; Liver; Male; Microscopy, Electron; Proteins; Rats; Rats, Inbred Strains; Taurocholic Acid | 1983 |
Development of intrahepatic cholestasis by alpha-naphthylisothiocyanate in rats.
Topics: 1-Naphthylisothiocyanate; Animals; Bile; Cell Membrane Permeability; Cholestasis, Intrahepatic; Disease Models, Animal; Liver; Male; Rats; Rats, Inbred Strains; Sulfobromophthalein; Taurocholic Acid; Time Factors | 1982 |
Mechanism of cholic acid protection in lithocholate-induced intrahepatic cholestasis in rats.
Topics: Albumins; Animals; Bile; Cell Membrane; Cholestasis, Intrahepatic; Cholesterol; Cholic Acids; Dehydrocholic Acid; Lithocholic Acid; Liver; Male; Phospholipids; Rats; Taurocholic Acid | 1980 |
Secretin prevents taurocholate-induced intrahepatic cholestasis in the rat.
Topics: Animals; Bile; Biological Transport; Chlorides; Cholestasis, Intrahepatic; Male; Rats; Rats, Wistar; Secretin; Sodium; Taurocholic Acid | 1994 |
Zonal changes of hepatobiliary taurocholate transport in intrahepatic cholestasis induced by 17 alpha-ethinyl estradiol: a histoautoradiographic study in rats.
Topics: Animals; Autoradiography; Bile Ducts; Biological Transport; Cholestasis, Intrahepatic; Ethinyl Estradiol; Image Processing, Computer-Assisted; Liver; Male; Rats; Rats, Wistar; Silver; Taurocholic Acid; Tissue Distribution | 1993 |
Intraabdominal sepsis down-regulates transcription of sodium taurocholate cotransporter and multidrug resistance-associated protein in rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Carrier Proteins; Cecum; Cholestasis, Intrahepatic; Gene Expression Regulation; Hyperbilirubinemia; Interleukin-6; Intestinal Perforation; Ion Transport; Ligation; Liver; Male; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters, Sodium-Dependent; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Symporters; Systemic Inflammatory Response Syndrome; Taurocholic Acid; Transcription, Genetic | 2000 |
The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions.
Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Bile Canaliculi; Bosentan; Cholestasis, Intrahepatic; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Endothelin Receptor Antagonists; Glyburide; Humans; Hypertension; Liver; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfonamides; Taurocholic Acid | 2001 |
Bile salt export pump is highly conserved during vertebrate evolution and its expression is inhibited by PFIC type II mutations.
Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Cholestasis, Intrahepatic; Cloning, Molecular; Conserved Sequence; Evolution, Molecular; Humans; Liver; Molecular Sequence Data; Mutation; Phylogeny; RNA, Messenger; Sequence Homology, Amino Acid; Skates, Fish; Spodoptera; Taurocholic Acid; Transfection | 2001 |
Potentiation of lithocholic-acid-induced cholestasis by methyl isobutyl ketone.
Topics: Animals; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Body Weight; Cholestasis, Intrahepatic; Drug Synergism; Lithocholic Acid; Male; Methyl n-Butyl Ketone; Organ Size; Rats; Rats, Inbred Strains; Taurocholic Acid | 1992 |
Increased paracellular permeability in intrahepatic cholestasis induced by carmustine (BCNU) in rats.
Topics: 1-Naphthylisothiocyanate; Animals; Bile; Biliary Tract; Carbon Radioisotopes; Carmustine; Cell Membrane Permeability; Cholestasis, Intrahepatic; Horseradish Peroxidase; Male; Phosphates; Rats; Rats, Inbred Strains; Sucrose; Taurocholic Acid | 1991 |