taurocholic acid has been researched along with Bile Duct Obstruction in 145 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (33.79) | 18.7374 |
| 1990's | 42 (28.97) | 18.2507 |
| 2000's | 22 (15.17) | 29.6817 |
| 2010's | 28 (19.31) | 24.3611 |
| 2020's | 4 (2.76) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, T; Iwasashi, H; Kakyo, M; Matsuno, S; Naitoh, T; Nakagomi, R; Nakai, D; Nishio, T; Seki, M; Suzuki, M; Tokui, T; Unno, M; Yawo, H | 1 |
| Green, RM; Hoda, F; Ward, KL | 1 |
| Brouwer, KLR; Fallon, JK; Fu, D; Ho, H; Honkakoski, P; Klein, A; Saran, C | 1 |
| Chen, M; Liang, Z; Sun, L; Tang, X; Yang, J | 1 |
| Beaudoin, JJ; Bezençon, J; Brouwer, KLR; Fallon, JK; Sjöstedt, N | 1 |
| Duan, Z; He, G; Zha, C; Zhang, W; Zhang, X | 1 |
| Blazquez, AMG; Cives-Losada, C; de la Iglesia, A; Macias, RIR; Marin, JJG; Monte, MJ | 1 |
| Burban, A; Guguen-Guillouzo, C; Guillouzo, A; Humbert, L; Rainteau, D; Sharanek, A | 1 |
| Adeyemi, O; Alvarez-Laviada, A; Glukhov, AV; Gorelik, J; Ibrahim, E; Schultz, F; Trauner, M; Williamson, C | 1 |
| Hirano, S; Kadowaki, F; Ohtsuki, S; Sasaki, K; Tachikawa, M; Terasaki, T; Uchida, Y; Watanabe, M | 1 |
| Ali, I; Beaudoin, JJ; Bezençon, J; Brouwer, KLR; Malinen, MM | 1 |
| Chen, XP; Ding, ZY; Jin, GN; Liang, HF; Ma, M; Yu, B; Zhang, BX | 1 |
| Cai, W; Lu, Y; Wang, Y; Xiao, Y; Yan, W; Zhou, K | 1 |
| Ali, I; Brouwer, KLR; Khalid, S; Stieger, B | 1 |
| Allen, KM; Copple, BL; Luyendyk, JP; O'Brien, KM; Rockwell, CE; Towery, K | 1 |
| Al-Attrache, H; Azzi, PB; Guguen-Guillouzo, C; Guillouzo, A; Humbert, L; Rainteau, D; Savary, CC; Sharanek, A | 1 |
| Abdel-Razzak, Z; Al-Attrache, H; Antherieu, S; Bachour-El Azzi, P; Guguen-Guillouzo, C; Guillouzo, A; Labbe, G; Lepage, S; Morel, I; Savary, CC; Sharanek, A | 1 |
| Eisses, JF; Husain, SZ; Le, T; Lemon, KL; Orabi, AI; Ozolek, JA; Pociask, DA | 1 |
| Cerny, D; Dolezelova, E; Farghali, H; Fuksa, L; Lenicek, M; Micuda, S; Muchova, L; Suk, J; Vanova, K; Vitek, L; Vreman, HJ; Wong, RJ; Zelenkova, M | 1 |
| Jaeschke, H; McGill, MR; Woolbright, BL; Yan, H | 1 |
| Cantore, M; Häussinger, D; Mayer, PG; Sommerfeld, A | 1 |
| Locher, KP; Mahdi, ZM; Stieger, B; Synal-Hermanns, U; Yoker, A | 1 |
| Alles, LK; Beuers, U; de Waart, DR; Heger, M; Kloek, JJ; Lionarons, DA; Marsman, HA; Paulusma, CC; Rusch, H; van der Mark, VA; van Golen, RF; van Gulik, TM; Verheij, J | 1 |
| Fuchs, CD; Halilbasic, E; Paumgartner, G; Trauner, M | 1 |
| Abu-Hayyeh, S; Marin, JJ; Marschall, HU; Martinez-Becerra, P; Rees, M; Romero, MR; Selden, C; Sheikh Abdul Kadir, SH; Williamson, C | 1 |
| Alpini, G; Carpino, G; Franchitto, A; Francis, H; Gaudio, E; Glaser, S; Kopriva, S; Mancinelli, R; Onori, P; Pannarale, L; Sferra, R; Ueno, Y; Venter, J; Vetuschi, A; White, M | 1 |
| Lenicek, M; Muchova, L; Petr, T; Sticova, E; Vanova, K; Vejrazka, M; Vitek, L; Vreman, HJ; Wong, RJ; Zelenka, J | 1 |
| Boaglio, AC; Crocenzi, FA; Mottino, AD; Ochoa, JE; Pellegrino, JM; Roma, MG; Sánchez Pozzi, EJ; Vore, M; Zucchetti, AE | 1 |
| Barbier, O; Białek, A; Caron, P; Milkiewicz, P; Straka, RJ; Trottier, J | 1 |
| Greupink, R; Huisman, MT; Monshouwer, M; Nabuurs, SB; Russel, FG; Verweij, V; Zarzycka, B | 1 |
| Barosso, IR; Boaglio, AC; Crocenzi, FA; Roma, MG; Sánchez Pozzi, EJ; Toledo, FD; Zucchetti, AE | 1 |
| Abdel-Razzak, Z; Anthérieu, S; Bachour-El Azzi, P; Dumont, J; Fromenty, B; Guguen-Guillouzo, C; Guillouzo, A; Robin, MA | 1 |
| Ito, K; Santa, T; Suzuki, H; Takada, T; Tan, JK; Yamamoto, H; Yoshikado, T | 1 |
| Isoherranen, N; Thummel, KE | 1 |
| de Swiet, M; Gorelik, J; Harding, SE; Koralage, D; Korchev, Y; Lab, M; Shevchuk, AI; Williamson, C | 1 |
| Dominguez, M; Macias, RI; Marin, JJ; Monte, MJ; Toledo, M; Vazquez, DJ; Villanueva, GR | 1 |
| Bobowiec, R; Gazzano, A; Martelli, F; Wójcik, M | 1 |
| Dutta, S; Häussinger, D; Kubitz, R; Kühlkamp, T; Saha, N; vom Dahl, S; Wettstein, M | 1 |
| Bull, LN; Elferink, RP; Eppens, EF; Freimer, NB; Groen, A; Killeen, NP; Knisely, AS; Kunne, C; Looije, N; Ottenhoff, R; Pawlikowska, L | 1 |
| de Swiet, M; Gorelik, J; Korchev, Y; Lab, M; Shevchuk, A; Williamson, C | 1 |
| Barritt, GJ; Gregory, RB; Hughes, R | 1 |
| Chang, P; Hung, DY; Roberts, MS; Siebert, GA | 1 |
| Kurihara, H; Sano, N; Takikawa, H | 1 |
| Bernt, C; Beuers, U; Rust, C; Vennegeerts, T | 1 |
| Akita, H; Hayashi, H; Hofmann, AF; Mita, S; Onuki, R; Sugiyama, Y; Suzuki, H | 1 |
| Beuers, U; Kerb, R; Kullak-Ublick, GA; Lang, C; Lang, T; Meier, PJ; Meier, Y; Pauli-Magnus, C; Stieger, B | 1 |
| Alpini, G; Alvaro, D; Benedetti, A; Fava, G; Francis, H; Glaser, S; Marzioni, M; Ueno, Y; Venter, J | 1 |
| Arias, IM; Ikeno, Y; Itoh, J; Kagawa, T; Mine, T; Mochizuki, K; Numari, A; Tanaka, H; Watanabe, N | 1 |
| Arimori, K; Ichihara, E; Iwakiri, T; Kai, H; Kumagai, Y; Matsunaga, N; Nagata, M; Okumura, M; Shiotsuki, S | 1 |
| Kameyama, J; Konno, Y; Momono, S; Sasaki, I; Sato, T | 1 |
| Fevery, J; Ricci, GL | 1 |
| Cornelis, M; De Groote, J; Fevery, J; Ricci, GL | 1 |
| Askew, AR; Balderson, G; Bates, GJ | 1 |
| Furuya, K; Kondo, Y; Tsuda, K | 1 |
| Kanai, S; Kitani, K | 2 |
| Chiarantini, E | 1 |
| Brock, WJ; Durham, S; Vore, M | 1 |
| Merrick, MV; Ross, HM; Simpson, JD; Soundy, RG | 1 |
| Hatoff, DE; Katz, RF; Ringard, AA | 1 |
| Balistreri, WF; Olinger, EJ; Ostrow, JD; Tarao, K | 1 |
| Höke, H; Krell, H; Pfaff, E | 1 |
| Gollan, JL; Green, RM; Rosenbluth, AB; Whiting, JF | 1 |
| Sano, N; Takikawa, H; Yamanaka, M; Yamazaki, R | 1 |
| Hayakawa, T; Hirano, A; Hoshino, M; Kamiya, Y; Katagiri, K; Kumai, T; Miyaji, M; Ohiwa, T; Takeuchi, T; Tanaka, A | 1 |
| Delabar, U; Enderle, GJ; Krell, H | 1 |
| Hayakawa, T; Hirano, A; Hoshino, M; Inagaki, T; Kamiya, Y; Kumai, T; Miyaji, M; Ohiwa, T; Takeuchi, T; Tanaka, A | 1 |
| Accatino, L; Amigo, L; Arrese, M; Garrido, J; González, S; Greco, AV; Mingrone, G; Núñez, L; Puglielli, L; Rigotti, A | 1 |
| Böhme, M; Jedlitschky, G; Keppler, D; Leier, I; Müller, M | 1 |
| Ishida, T; Kaneko, JJ; Tomoda, I; Washizu, M; Washizu, T | 1 |
| Kanai, S; Kitani, K; Ohta, M; Sato, Y | 1 |
| Beuers, U; Boyer, JL; Isales, CM; Nathanson, MH | 1 |
| Accatino, L; Arrese, M; Pizarro, M; Solis, N; Wielandt, AM | 1 |
| Bossard, R; Fricker, G; Meier, PJ; O'Neill, B; Stieger, B | 1 |
| Kajiyama, G; Miura, H; Tazuma, S | 1 |
| Neghab, M; Stacey, NH | 1 |
| Alvaro, I; Arevalo, M; Macias, RI; Marin, JJ; Monte, MJ; Morales, AI | 1 |
| Beier, D; Gollan, JL; Green, RM | 1 |
| Bernard, B; Bouvier, E; Cabrol, A; Cadranel, JF; Dorent, R; Gandjbakhch, I; Gerhardt, M; Ghoussoub, JJ; Lunel, F; Myara, A; Opolon, P; Trivin, F | 1 |
| Ananthanarayanan, M; Lown, K; Moseley, RH; Shick, L; Suchy, FJ; Takeda, H; Wang, W | 1 |
| Meier-Abt, PJ | 1 |
| Bolder, U; Frick, E; Hofmann, AF; Schteingart, CD; Ton-Nu, HT | 1 |
| Moseley, RH | 1 |
| Chazouillères, O; Haniche, M; Jian, R; Marteau, P; Poupon, R | 1 |
| Boyer, JL; Gartung, C; Schlosser, SF; Schuele, S | 1 |
| Meier, PJ; O'Neill, B; Sjövall, J; Stieger, B; Zhang, J | 1 |
| Aiso, M; Sano, N; Takamori, Y; Takikawa, H; Yamanaka, M | 1 |
| Bouscarel, B; Ceryak, S; Fromm, H; Gettys, TW; Le, M; Matsuzaki, Y; Shoda, J | 1 |
| Beuers, U; Fahney, C; Hagenbuch, B; Kullak-Ublick, GA; Meier, PJ; Paumgartner, G | 1 |
| Baraldini, M; Cantelli Forti, G; Cerré, C; Guerra, MC; Piazza, F; Roda, A; Speroni, E | 1 |
| Gavino, V; LeBlanc, MJ; Lévy, E; Pérea, A; Tuchweber, B; Yousef, IM | 1 |
| Arrese, M; Crossman, MW; Sacchiero, RJ; Shneider, BL; Trauner, M | 1 |
| Hoffmann, WE; Solter, PF | 1 |
| Bouchard, G; Tuchweber, B; Yousef, IM | 1 |
| Huang, L; Meijer, DK; Smit, JW; Vore, M | 1 |
| Alponat, A; Altinkaya, E; Göksel, S; Sariyar, M; Sayan, M; Yavuz, N | 1 |
| Arias, IM; Kipp, H | 1 |
| de Swiet, M; Eaton, BM; Gorelik, J; Korchev, Y; Lab, M; Williamson, C | 1 |
| Crocenzi, FA; Dawson, PA; Mottino, AD; Pellegrino, JM; Roma, MG; Sánchez Pozzi, EJ; Veggi, LM | 1 |
| Kim, YH; Shin, MJ | 1 |
| Gromova, OA; Lyakhovich, VV; Pospelova, LN; Tsyrlov, IB; Zakharova-Polyakova, NE | 1 |
| Baker, AL; Cooper, MJ; Hall, TJ; Moossa, AR | 1 |
| Carey, MC; Ros, E; Small, DM | 1 |
| Bomzon, L; Kew, MC; Mendelsohn, D; Wilton, PB | 1 |
| Accatino, L; Contreras, A; Fernańdez, S; Quintana, C | 1 |
| Drew, R; Priestly, BG | 1 |
| Greim, H; Pfaff, E; Schwarz, LR; Schwenk, M | 1 |
| Bailey, ME | 1 |
| Boyer, JL; Layden, TJ | 2 |
| Adler, RD; Ockner, RK; Wannagat, FJ | 1 |
| Bradley, SE; Herz, R | 1 |
| Clarke, AE; Denborough, MA; Maritz, VM | 1 |
| Paumgartner, G; Preisig, R; Reichen, J; von Bergmann, K | 1 |
| Berndt, WO; Cooke, WJ; Mudge, GH | 1 |
| Klapdor, R; Schliewe, J; Valerius, H | 1 |
| Hayakawa, T; Hoshino, M; Katagiri, K; Nakai, T; Ohiwa, T | 1 |
| Carnovale, C; Rodíguez Garay, A; Roma, MG | 1 |
| Hayakawa, T; Hoshino, M; Katagiri, K; Miyaji, M; Nakai, T; Ohiwa, T; Ohnishi, H; Okayama, Y; Takeuchi, T; Yamada, T | 1 |
| Kameyama, J; Kaneko, K; Suzuki, A; Suzuki, Y; Tsukamoto, M | 1 |
| Abernathy, CO; Gillespie, J; Tripodi, MF; Utili, R; Zimmerman, HJ | 1 |
| Clark, NW; Plusa, SM | 1 |
| Akerboom, T; Schneider, I; Sies, H; vom Dahl, S | 1 |
| Abernathy, CO; Adinolfi, LE; Gaeta, GB; Tripodi, MF; Utili, R; Zimmerman, HJ | 1 |
| Berenson, MM; Bjorkman, DJ; Gunther, C; Samowitz, WS | 1 |
| Fukushima, K; Funayama, Y; Kamiyama, Y; Matsuno, S; Matsuo, T; Naitoh, H; Sasaki, I; Takahashi, M | 1 |
| Buscher, HP; Gerok, W; MacNelly, S; Miltenberger, C | 1 |
| Luquita, MG; Rodríguez Garay, EA; Roma, MG | 1 |
| Kanai, S; Kitani, K; Ohta, M | 1 |
| Akerboom, T; Lenzen, R; Schneider, I; Sies, H | 1 |
| Bailey, ME; Pain, JA | 1 |
| Akagi, M; Harada, K; Misumi, A; Mizumoto, S; Takano, S | 1 |
| Durham, S; Vore, M | 1 |
| Tsuda, K | 1 |
| Minuk, GY; Pai, CH; Rascanin, N; Sarjeant, ES | 1 |
| Berr, F; Le, M; Reichen, J; Warren, GH | 1 |
| Billing, BH; Chitranukroh, A; Taggart, G | 1 |
| Elias, E; Iqbal, S; Mills, CO | 1 |
| Imoto, M; Nishimura, D; Ozawa, T; Satake, T; Sugiyama, S | 1 |
| Czygan, P; Greim, H; Trültsch, D | 1 |
| Cooper, DY; Czygan, P; Greim, H; Hutterer, F; Popper, H; Rosenthal, O; Schaffner, F; Trülzsch, D | 1 |
| Makino, I; Mashimo, K; Nakagawa, S; Shinozaki, K | 1 |
| Bode, JC; Neuberger, HO; Zelder, O | 1 |
| Dubois, RS; Laurendeau, G; Ling, V; Morin, CL; Roy, CC; Weber, AM | 1 |
| Liersch, M; Stiehl, A | 1 |
3 review(s) available for taurocholic acid and Bile Duct Obstruction
| Article | Year |
|---|---|
New therapeutic concepts in bile acid transport and signaling for management of cholestasis.
Topics: Animals; Bile Acids and Salts; Biological Transport; Cholestasis; Cohort Studies; Disease Models, Animal; Humans; Liver Circulation; Severity of Illness Index; Signal Transduction; Taurocholic Acid; Treatment Outcome | 2017 |
Intracellular trafficking and regulation of canalicular ATP-binding cassette transporters.
Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Bile Canaliculi; Biological Transport, Active; Cholestasis; Cyclic AMP; Hepatocytes; Humans; Phosphatidylinositol 3-Kinases; Rats; Taurocholic Acid | 2000 |
Elaboration of hepatocytic bile.
Topics: Albumins; Animals; Atrophy; Bile; Bile Acids and Salts; Cholestasis; Endoplasmic Reticulum; Erythrocytes; Humans; Kinetics; Liver; Microsomes, Liver; Organ Size; Sodium; Taurocholic Acid | 1975 |
3 trial(s) available for taurocholic acid and Bile Duct Obstruction
| Article | Year |
|---|---|
The response of bile secretion and ubiquinone Q10 to hyperglycaemia in sheep.
Topics: Animals; Bile; Bile Acids and Salts; Blood Glucose; Cholestasis; Coenzymes; Glucose; Hyperglycemia; Insulin; Liver; Sheep; Sheep Diseases; Taurocholic Acid; Ubiquinone | 2003 |
Ileal absorption of bile acids in patients with chronic cholestasis: SeHCAT test results and effect of ursodeoxycholic acid (UDCA).
Topics: Alkaline Phosphatase; Bile Acids and Salts; Cholestasis; Chronic Disease; Down-Regulation; Female; gamma-Glutamyltransferase; Humans; Ileum; Intestinal Absorption; Liver Cirrhosis; Male; Middle Aged; Selenium Radioisotopes; Taurocholic Acid; Up-Regulation; Ursodeoxycholic Acid | 1996 |
Prevention of postoperative renal dysfunction in patients with obstructive jaundice: a comparison of mannitol-induced diuresis and oral sodium taurocholate.
Topics: Acute Kidney Injury; Administration, Oral; Aged; Cholestasis; Creatinine; Female; Humans; Incidence; Infusions, Intravenous; Male; Mannitol; Middle Aged; Postoperative Complications; Premedication; Taurocholic Acid | 1991 |
139 other study(ies) available for taurocholic acid and Bile Duct Obstruction
| Article | Year |
|---|---|
Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Blotting, Northern; Carrier Proteins; Cecum; Cholestasis; Common Bile Duct; Feedback; Female; Gene Expression Regulation; Ligation; Liver; Molecular Sequence Data; Oocytes; Punctures; Rats; RNA, Messenger; Xenopus laevis | 1999 |
Molecular cloning and characterization of the murine bile salt export pump.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Blotting, Western; Cell Line; Cell Membrane; Cholagogues and Choleretics; Cholestasis; Cloning, Molecular; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Rats; Sequence Homology, Amino Acid; Taurocholic Acid; Transfection | 2000 |
A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity.
Topics: Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Hepatocytes; Humans; Liver; Membrane Transport Proteins; Organic Anion Transporters, Sodium-Dependent; Symporters; Taurocholic Acid | 2022 |
Taurocholic acid promotes hepatic stellate cell activation via S1PR2/p38 MAPK/YAP signaling under cholestatic conditions.
Topics: Animals; Cholestasis; Fibrosis; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Mice; Sphingosine-1-Phosphate Receptors; Taurocholic Acid | 2023 |
Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions.
Topics: Animals; Bile Acids and Salts; Biological Transport; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; Drug Interactions; Hepatocytes; Humans; Ion Transport; Kinetics; Liver; Membrane Transport Proteins; Pharmaceutical Preparations; Proteomics; Taurocholic Acid | 2020 |
Long-term intervention of taurocholic acid over-expressing in cholestatic liver disease inhibits the growth of hepatoma cells.
Topics: Apoptosis; Calcium; CCAAT-Enhancer-Binding Proteins; Cell Line; Cell Survival; Cholestasis; Hep G2 Cells; Hepatocytes; Humans; Proto-Oncogene Proteins c-myc; Reactive Oxygen Species; Taurocholic Acid; Tumor Necrosis Factor-alpha | 2020 |
Lactation during cholestasis: Role of ABC proteins in bile acid traffic across the mammary gland.
Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholestasis; Female; Gene Expression Regulation; Lactation; Mammary Glands, Animal; Mice; Pregnancy; Rats; Taurocholic Acid | 2017 |
Progressive and Preferential Cellular Accumulation of Hydrophobic Bile Acids Induced by Cholestatic Drugs Is Associated with Inhibition of Their Amidation and Sulfation.
Topics: Amides; Bile Acids and Salts; Cell Line; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Humans; Lithocholic Acid; Liver; Organic Anion Transporters, Sodium-Dependent; Sulfates; Symporters; Taurocholic Acid | 2017 |
Ursodeoxycholic acid prevents ventricular conduction slowing and arrhythmia by restoring T-type calcium current in fetuses during cholestasis.
Topics: Animals; Calcium; Calcium Channels, T-Type; Cholestasis; Electrophysiological Phenomena; Female; Fetal Heart; Heart Ventricles; Humans; Myocytes, Cardiac; Pregnancy; Rats; Taurocholic Acid; Ursodeoxycholic Acid | 2017 |
ATP-Binding Cassette Transporter A Subfamily 8 Is a Sinusoidal Efflux Transporter for Cholesterol and Taurocholate in Mouse and Human Liver.
Topics: Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Capillaries; Cholestasis; Cholesterol; Disease Models, Animal; HEK293 Cells; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Proteomics; Taurocholic Acid | 2018 |
Organic solute transporter OSTα/β is overexpressed in nonalcoholic steatohepatitis and modulated by drugs associated with liver injury.
Topics: Bile Acids and Salts; Biological Transport; Biomarkers; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Glycochenodeoxycholic Acid; Hepatocytes; Humans; Liver; Liver Cirrhosis, Biliary; Male; Membrane Transport Proteins; Middle Aged; Non-alcoholic Fatty Liver Disease; Taurocholic Acid | 2018 |
Taurocholate Induces Connective Tissue Growth Factor Expression in Hepatocytes Through ERK-YAP Signaling.
Topics: Animals; Apoptosis Regulatory Proteins; Butadienes; Cell Line; Cholestasis; Connective Tissue Growth Factor; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Liver; Male; MAP Kinase Kinase 1; Nitriles; Porphyrins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Signal Transduction; Taurocholic Acid; Up-Regulation; Verteporfin; YAP-Signaling Proteins | 2018 |
Administration of antibiotics contributes to cholestasis in pediatric patients with intestinal failure via the alteration of FXR signaling.
Topics: Animals; Bacterial Proteins; Bacteroides; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cholestasis; Cytochrome P-450 Enzyme System; Eubacterium; Female; Fibroblast Growth Factors; Gastrointestinal Microbiome; Gentamicins; Gram-Positive Bacteria; Humans; Infant; Intestines; Liver; Male; Mice; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Taurocholic Acid; Vancomycin | 2018 |
Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Baculoviridae; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Dipyridamole; Erythromycin; Glycocholic Acid; Ketoconazole; Kinetics; Membrane Transport Proteins; Polymorphism, Single Nucleotide; Sf9 Cells; Signal Transduction; Spodoptera; Taurocholic Acid; Transport Vesicles | 2019 |
IL-17A synergistically enhances bile acid-induced inflammation during obstructive cholestasis.
Topics: Actins; Animals; Antibodies, Neutralizing; Bile Acids and Salts; Bile Ducts; Biomarkers; Cell Count; Chemokine CXCL2; Cholestasis; Collagen Type I; Hepatocytes; Inflammation; Interleukin-17; Interleukin-23; Ligation; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutralization Tests; Neutrophils; RNA, Messenger; Signal Transduction; Taurocholic Acid; Up-Regulation | 2013 |
Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells.
Topics: Actins; Cell Line, Tumor; Cell Survival; Cholestasis; Cyclosporine; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Gene Expression; Humans; Immunosuppressive Agents; Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Taurocholic Acid; Time-Lapse Imaging | 2014 |
Impact of inflammation on chlorpromazine-induced cytotoxicity and cholestatic features in HepaRG cells.
Topics: Actins; Bile Acids and Salts; C-Reactive Protein; Cell Line; Chlorpromazine; Cholestasis; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Down-Regulation; Humans; Inflammation; Interleukins; Organic Anion Transporters, Sodium-Dependent; Oxidative Stress; RNA, Messenger; Symporters; Taurocholic Acid | 2014 |
Intraductal infusion of taurocholate followed by distal common bile duct ligation leads to a severe necrotic model of pancreatitis in mice.
Topics: Amylases; Animals; Bilirubin; Biomarkers; Cholestasis; Common Bile Duct; Disease Models, Animal; Gallstones; Interleukin-6; Ligation; Male; Mice; Pancreas; Pancreatitis, Acute Necrotizing; Severity of Illness Index; Taurocholic Acid; Time Factors | 2015 |
Protective effect of heme oxygenase induction in ethinylestradiol-induced cholestasis.
Topics: Alkaline Phosphatase; Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Bilirubin; Cells, Cultured; Cholestasis; Enzyme Induction; Ethinyl Estradiol; Female; Gene Expression; Heme; Heme Oxygenase (Decyclizing); Hepatocytes; Multidrug Resistance-Associated Proteins; Primary Cell Culture; Protective Agents; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Taurocholic Acid | 2015 |
Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Bile Acids and Salts; Cholestasis; Glycochenodeoxycholic Acid; Hep G2 Cells; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Protective Agents; Taurocholic Acid | 2016 |
Regulation of plasma membrane localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by hyperosmolarity and tauroursodeoxycholate.
Topics: Animals; Bile Acids and Salts; Calcium; Cell Membrane; Cells, Cultured; Cholestasis; Densitometry; Gene Expression Regulation, Enzymologic; Hep G2 Cells; Hepatocytes; Humans; Integrin beta1; Liver; Male; Mice; Organic Anion Transporters, Sodium-Dependent; Osmolar Concentration; Oxidative Stress; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-fyn; Rats; Rats, Wistar; Reactive Oxygen Species; Serine; Signal Transduction; Sodium; Symporters; Taurocholic Acid | 2015 |
Role of Multidrug Resistance Protein 3 in Antifungal-Induced Cholestasis.
Topics: Animals; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azoles; Bile Acids and Salts; Biological Transport; Blotting, Western; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Humans; LLC-PK1 Cells; Phospholipids; Reproducibility of Results; Swine; Taurocholic Acid | 2016 |
Simple steatosis sensitizes cholestatic rats to liver injury and dysregulates bile salt synthesis and transport.
Topics: Animals; Bile Acids and Salts; Biological Transport, Active; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Hep G2 Cells; Humans; Liver; Non-alcoholic Fatty Liver Disease; Rats; Taurocholic Acid | 2016 |
Inhibition of Na+-taurocholate Co-transporting polypeptide-mediated bile acid transport by cholestatic sulfated progesterone metabolites.
Topics: Animals; Bile Acids and Salts; Binding, Competitive; Cell Line, Tumor; Cholestasis; Cobalt; Dose-Response Relationship, Drug; Female; Hepatocytes; Humans; Models, Biological; Oocytes; Peptides; Pregnancy; Progesterone; Sodium; Steroids; Taurocholic Acid; Xenopus laevis | 2010 |
Taurocholic acid prevents biliary damage induced by hepatic artery ligation in cholestatic rats.
Topics: Animals; Bile Ducts; Cell Proliferation; Cells, Cultured; Cholagogues and Choleretics; Cholestasis; Disease Models, Animal; Hepatic Artery; Immunohistochemistry; Ligation; Male; Rats; Rats, Inbred F344; Taurocholic Acid; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2010 |
Bile acids decrease intracellular bilirubin levels in the cholestatic liver: implications for bile acid-mediated oxidative stress.
Topics: Animals; Bile Acids and Salts; Bilirubin; Cell Line, Tumor; Cholestasis; Female; Heme Oxygenase (Decyclizing); Humans; Intracellular Space; Lipid Peroxidation; Liver; Oxidative Stress; Rats; Rats, Gunn; Rats, Wistar; Taurocholic Acid | 2011 |
Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17β-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C.
Topics: 1-Phosphatidylinositol 4-Kinase; Androstadienes; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Canaliculi; Biliary Tract; Carbazoles; Cholestasis; Colchicine; Endocytosis; Estradiol; Glutathione; In Vitro Techniques; Male; Microtubules; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Perfusion; Protein Kinase C; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Taurocholic Acid; Wortmannin | 2010 |
Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting.
Topics: Bile Acids and Salts; Case-Control Studies; Cholestasis; Constriction, Pathologic; Female; Glycocholic Acid; Humans; Male; Stents; Taurocholic Acid | 2011 |
In silico identification of potential cholestasis-inducing agents via modeling of Na(+)-dependent taurocholate cotransporting polypeptide substrate specificity.
Topics: Animals; CHO Cells; Cholestasis; Computer Simulation; Cricetinae; Cricetulus; Humans; Male; Models, Biological; Organic Anion Transporters, Sodium-Dependent; Peptides; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Substrate Specificity; Taurocholic Acid | 2012 |
ERK1/2 and p38 MAPKs are complementarily involved in estradiol 17ß-D-glucuronide-induced cholestasis: crosstalk with cPKC and PI3K.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Blotting, Western; Cholestasis; Estradiol; Female; Hepatocytes; Image Processing, Computer-Assisted; MAP Kinase Signaling System; Microscopy, Confocal; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Statistics, Nonparametric; Taurocholic Acid | 2012 |
Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells.
Topics: Actins; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Carcinoma, Hepatocellular; Cell Line, Tumor; Chlorpromazine; Cholestasis; Humans; In Vitro Techniques; Liver Neoplasms; Membrane Potential, Mitochondrial; Oxidative Stress; Reactive Oxygen Species; Taurocholic Acid | 2013 |
Ticlopidine, a cholestatic liver injury-inducible drug, causes dysfunction of bile formation via diminished biliary secretion of phospholipids: involvement of biliary-excreted glutathione-conjugated ticlopidine metabolites.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Biliary Tract; Biological Transport; Chemical and Drug Induced Liver Injury; Cholestasis; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Membrane Transport Proteins; Phospholipids; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Ticlopidine | 2013 |
Drug metabolism and transport during pregnancy: how does drug disposition change during pregnancy and what are the mechanisms that cause such changes?
Topics: 17 alpha-Hydroxyprogesterone Caproate; Adrenal Glands; Animals; Aryldialkylphosphatase; ATP-Binding Cassette Transporters; Carboxylesterase; Cholestasis; Cotinine; Cytochrome P-450 Enzyme System; Estradiol; Estrogen Receptor alpha; Estrogens; Ethinyl Estradiol; Female; Fetus; Gene Expression Regulation, Developmental; Glucuronosyltransferase; Hepatocytes; Humans; Hydroxyprogesterones; Intestine, Small; Kidney; Liver; Lung; Male; Maternal Behavior; Membrane Transport Proteins; Minor Histocompatibility Antigens; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Pesticides; Placenta; Pregnancy; Progesterone; Retinoic Acid 4-Hydroxylase; RNA, Messenger; Smoking; Taurocholic Acid | 2013 |
Taurocholate induces changes in rat cardiomyocyte contraction and calcium dynamics.
Topics: Animals; Calcium; Cell Size; Cells, Cultured; Cholagogues and Choleretics; Cholestasis; Female; Fetal Death; Humans; Male; Models, Animal; Myocardial Contraction; Myocardium; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 2002 |
Effect of maternal obstructive cholestasis during pregnancy on the biliary transport of horseradish peroxidase in the rat offspring.
Topics: Animals; Bile; Biological Transport; Brefeldin A; Cholagogues and Choleretics; Cholestasis; Female; Hepatocytes; Horseradish Peroxidase; Immunoblotting; Immunohistochemistry; Microscopy, Confocal; Microtubules; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Taurocholic Acid; Time Factors; Tubulin | 2003 |
Ca2+-dependent protein kinase C isoforms induce cholestasis in rat liver.
Topics: Animals; Bacterial Proteins; Bile; Biological Transport; Blotting, Western; Calcium; Carbazoles; Cell Line; Cell Membrane; Cells, Cultured; Cholestasis; Cloning, Molecular; Densitometry; Detergents; Dose-Response Relationship, Drug; Enzyme Activation; Hepatocytes; Humans; Indoles; Liver; Luminescent Proteins; Male; Maleimides; Microscopy, Confocal; Models, Biological; Perfusion; Phorbol Esters; Polymerase Chain Reaction; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Signal Transduction; Taurocholic Acid; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 2004 |
A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion.
Topics: Adenosine Triphosphatases; Animals; Bile; Bile Acids and Salts; Cholestasis; Disease Models, Animal; Liver; Male; Mice; Phospholipid Transfer Proteins; Taurocholic Acid; Tritium | 2004 |
Comparison of the arrhythmogenic effects of tauro- and glycoconjugates of cholic acid in an in vitro study of rat cardiomyocytes.
Topics: Animals; Arrhythmias, Cardiac; Cholestasis; Cholic Acid; Female; Glycoconjugates; Myocardial Contraction; Myocytes, Cardiac; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Taurocholic Acid | 2004 |
Induction of cholestasis in the perfused rat liver by 2-aminoethyl diphenylborate, an inhibitor of the hepatocyte plasma membrane Ca2+ channels.
Topics: Animals; Bile; Boron Compounds; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cholestasis; Enzyme Inhibitors; Glucagon; Hepatocytes; Hydroquinones; Liver; Peptide Hormones; Rats; Taurocholic Acid; Vasopressins | 2004 |
Hepatic pharmacokinetics of taurocholate in the normal and cholestatic rat liver.
Topics: Animals; Biological Transport; Cholestasis; Dose-Response Relationship, Drug; Ethinyl Estradiol; Liver; Male; Models, Biological; Rats; Rats, Wistar; Taurocholic Acid | 2005 |
Biliary excretion of taurocholate, organic anions and vinblastine in rats with alpha-naphthylisothiocyanate-induced cholestasis.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Anions; Antineoplastic Agents, Phytogenic; Bile; Bile Acids and Salts; Biological Transport; Cholagogues and Choleretics; Cholestasis; Disease Models, Animal; Male; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Vinblastine | 2005 |
The human transcription factor AP-1 is a mediator of bile acid-induced liver cell apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Bile Acids and Salts; Cell Line; Cell Line, Tumor; Cholestasis; Curcumin; Detergents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genes, Reporter; Glycochenodeoxycholic Acid; Hepatocytes; Humans; Immunoblotting; Liver; Luciferases; MAP Kinase Signaling System; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Taurocholic Acid; Time Factors; Transcription Factor AP-1; Transcription, Genetic; Up-Regulation | 2006 |
Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport; Cholestasis; Cyclosporine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoresceins; Kinetics; LLC-PK1 Cells; Organic Anion Transporters, Sodium-Dependent; Oxadiazoles; Rifampin; Rifamycins; Swine; Symporters; Taurocholic Acid; Transfection | 2006 |
Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Genetic Predisposition to Disease; Humans; Liver Diseases; Male; Middle Aged; Molecular Sequence Data; Mutation; Polymorphism, Genetic; Protein Structure, Secondary; Taurocholic Acid; White People | 2007 |
Cytoprotective effects of taurocholic acid feeding on the biliary tree after adrenergic denervation of the liver.
Topics: Adrenergic Agents; Androstadienes; Animals; Apoptosis; Biliary Tract; Cell Proliferation; Cholestasis; Denervation; Liver; Phosphoinositide-3 Kinase Inhibitors; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Strains; Taurocholic Acid; Wortmannin | 2007 |
Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells.
Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Cell Line; Cholestasis; Cholestasis, Intrahepatic; Dogs; Genotype; Half-Life; Models, Molecular; Molecular Sequence Data; Mutation; Phenotype; Protein Conformation; Protein Transport; Rats; RNA, Messenger; Taurocholic Acid; Time Factors; Transfection | 2008 |
Hepatocyte growth factor increases uptake of estradiol 17beta-D-glucuronide and Oatp1 protein level in rat hepatocytes.
Topics: Animals; Cells, Cultured; Cholestasis; Estradiol; Gene Expression Regulation; Hepatocyte Growth Factor; Hepatocytes; Male; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Wistar; RNA, Messenger; Taurocholic Acid; Ubiquitination | 2008 |
Influence of obstructive jaundice on gastric mucosal barrier in dogs.
Topics: Animals; Cholestasis; Dogs; Dose-Response Relationship, Drug; Gastric Mucosa; Membrane Potentials; Permeability; Protons; Sodium; Taurocholic Acid | 1984 |
Cholestatic action of somatostatin in the rat: effect on the different fractions of bile secretion.
Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Cholestasis; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Rats; Somatostatin; Taurocholic Acid | 1981 |
Maximal hepatic bilirubin transport in the rat during somatostatin-induced cholestasis and taurocholate-choleresis.
Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Biological Transport; Cholestasis; Liver; Male; Rats; Rats, Inbred Strains; Somatostatin; Taurocholic Acid | 1983 |
Jaundice and the effect of sodium taurocholate taken orally upon abdominal wound healing.
Topics: Administration, Oral; Animals; Bile Ducts; Cholestasis; Female; Hydroxyproline; Ligation; Premedication; Rats; Rats, Inbred Strains; Taurocholic Acid; Wound Healing | 1984 |
[Enhancement of sulfobromophthalein excretion by taurocholate in the rat with relieved biliary obstruction].
Topics: Animals; Bile; Cholestasis; Liver; Male; Rats; Rats, Inbred Strains; Sulfobromophthalein; Taurocholic Acid | 1984 |
Glycoursodeoxycholate is as effective as tauroursodeoxycholate in preventing the taurocholate-induced cholestasis in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Drug Evaluation, Preclinical; Rats; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1983 |
Hepatocyte taurocholic acid uptake in the regression of ethinyl estradiol cholestasis. Preliminary results.
Topics: Animals; Cholestasis; Ethinyl Estradiol; Female; Liver; Perfusion; Rats; Rats, Inbred Strains; Taurocholic Acid | 1984 |
Characterization of the interaction between estrogen metabolites and taurocholate for uptake into isolated hepatocytes. Lack of correlation between cholestasis and inhibition of taurocholate uptake.
Topics: Animals; Cholestasis; Dihydrotestosterone; Estradiol; Estriol; Estrogens; Ethinyl Estradiol; Female; In Vitro Techniques; Liver; Rats; Rats, Inbred Strains; Taurocholic Acid | 1984 |
Absorbed dose to man from the Se-75 labeled conjugated bile salt SeHCAT: concise communication.
Topics: Administration, Oral; Animals; Body Burden; Cholestasis; Energy Transfer; Gallbladder; Humans; Injections, Intravenous; Mice; Radiation Dosage; Radioisotopes; Rats; Selenium; Taurocholic Acid; Time Factors; Tissue Distribution; Whole-Body Counting | 1982 |
Induction of hepatic alkaline phosphatase by colchicine: role of cholestasis and bile acids.
Topics: Alkaline Phosphatase; Animals; Bile Acids and Salts; Cholestasis; Colchicine; Enzyme Induction; Liver; Male; Rats; Rats, Inbred Strains; Taurocholic Acid | 1983 |
Tauroursodeoxycholate prevents taurocholate induced cholestasis.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Kinetics; Male; Rats; Rats, Inbred WF; Taurochenodeoxycholic Acid; Taurocholic Acid | 1982 |
Impaired bile acid efflux from hepatocytes isolated from the liver of rats with cholestasis.
Topics: Animals; Cholestasis; Cholic Acids; Ethinyl Estradiol; Glycocholic Acid; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Taurocholic Acid | 1982 |
Are findings with isolated rat livers after short calcium free perfusion relevant for isolated cells?
Topics: Animals; Calcium; Cholestasis; Glutathione; In Vitro Techniques; Inulin; Liver; Male; Rats; Sulfobromophthalein; Taurocholic Acid; Time Factors | 1980 |
Tumor necrosis factor-alpha decreases hepatocyte bile salt uptake and mediates endotoxin-induced cholestasis.
Topics: Animals; Antibodies, Monoclonal; Bile; Bile Acids and Salts; Cells, Cultured; Cholestasis; Endotoxins; Kinetics; Liver; Male; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Tumor Necrosis Factor-alpha | 1995 |
Colchicine inhibits lithocholate-3-O-glucuronide-induced cholestasis in rats.
Topics: Animals; Bile; Cholestasis; Colchicine; Glucuronates; Lithocholic Acid; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid; Vinblastine | 1995 |
Comparative studies on bile flow and biliary lipid excretion after bile-acid loading in normal and partially hepatectomized rats.
Topics: Animals; Bile; Bilirubin; Cholestasis; Enzymes; Hepatectomy; Horseradish Peroxidase; In Vitro Techniques; Liver Regeneration; Male; Perfusion; Phospholipids; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 1995 |
Different pathomechanisms of altered biliary leukotriene C4 elimination in isolated perfused rat livers.
Topics: 1-Naphthylisothiocyanate; Animals; Bile; Cholestasis; Estradiol; Ethionine; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Leukotriene C4; Liver; Male; Perfusion; Rats; Rats, Wistar; Taurocholic Acid | 1995 |
The mutant Eisai hyperbilirubinemic rat is resistant to bile acid-induced cholestasis and cytotoxicity.
Topics: Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Cholestasis; Horseradish Peroxidase; Hyperbilirubinemia; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Phospholipids; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1994 |
Protective role of biliary cholesterol and phospholipid lamellae against bile acid-induced cell damage.
Topics: Animals; Bile; Bile Acids and Salts; Bile Canaliculi; Cell Death; Cholestasis; Cholesterol; Diosgenin; Dose-Response Relationship, Drug; Erythrocytes; Intracellular Membranes; Liver; Male; Microscopy, Electron; Phospholipids; Rats; Rats, Wistar; Taurocholic Acid | 1994 |
Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver.
Topics: Adenosine Triphosphate; Animals; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Carbon Radioisotopes; Cell Membrane; Cholestasis; Cyclosporine; Cyclosporins; In Vitro Techniques; Leukotriene C4; Liver; Male; Rats; Rats, Wistar; Taurocholic Acid; Time Factors | 1994 |
Changes in bile acid composition of serum and gallbladder bile in bile duct ligated dogs.
Topics: Animals; Bile Acids and Salts; Bile Ducts; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Dogs; Gallbladder; Lithocholic Acid; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Time Factors | 1994 |
Tauro alpha-muricholate is as effective as tauro beta-muricholate and tauroursodeoxycholate in preventing taurochenodeoxycholate-induced liver damage in the rat.
Topics: Albumins; Animals; Bile; Cholestasis; Isomerism; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid | 1994 |
Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis.
Topics: Acetylglucosaminidase; Animals; Bile; Biomarkers; Calcium; Cells, Cultured; Cholestasis; Cytosol; Exocytosis; Extracellular Space; Horseradish Peroxidase; Kinetics; Liver; Lysosomes; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Reference Values; Taurochenodeoxycholic Acid; Taurocholic Acid; Vasopressins | 1993 |
Postcholestatic alkaline phosphatase activity after relief of bile duct obstruction in the rat.
Topics: Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Bile Canaliculi; Cell Membrane; Cholestasis; Kinetics; Liver; Male; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 1993 |
Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver.
Topics: Adenosine; Animals; Bile; Bile Canaliculi; Biological Transport; Blood Chemical Analysis; Body Weight; Cell Membrane; Cell Polarity; Cholestasis; Ethinyl Estradiol; Glutathione; Glycine; Liver; Male; Organ Size; Rats; Rats, Sprague-Dawley; Sulfates; Taurocholic Acid | 1993 |
Partial characterization of regulation of biliary lecithin hydrophobicity: association with organic anion-induced solute cholestasis in rats.
Topics: Animals; Anions; Bile; Bile Acids and Salts; Chemical Phenomena; Chemistry, Physical; Cholestasis; Cholesterol; Lipid Metabolism; Male; Micelles; Phosphatidylcholines; Phospholipids; Rats; Rats, Sprague-Dawley; Sulfobromophthalein; Taurocholic Acid | 1995 |
Alpha-naphthylisothiocyanate-induced elevation of serum bile acids: lack of causative effect on bile acid transport.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Bile Acids and Salts; Biological Transport; Cell Survival; Cholestasis; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 1996 |
Reversible impairment of neonatal hepatobiliary function by maternal cholestasis.
Topics: Animals; Animals, Newborn; Bile; Bile Acids and Salts; Biliary Tract; Bilirubin; Cholagogues and Choleretics; Cholestasis; Female; Fetal Organ Maturity; Liver; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Sulfobromophthalein; Taurocholic Acid | 1996 |
Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents.
Topics: Animals; Bile Acids and Salts; Blotting, Northern; Blotting, Western; Carrier Proteins; Cholestasis; Cytokines; Gene Expression; Inflammation Mediators; Interleukin-1; Interleukin-6; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Organic Anion Transporters, Sodium-Dependent; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Symporters; Taurocholic Acid; Tumor Necrosis Factor-alpha | 1996 |
Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Cyclosporine; Fasting; Female; Glycocholic Acid; Heart Transplantation; Hepatitis, Chronic; Humans; Immunosuppressive Agents; Lithocholic Acid; Male; Middle Aged; Spectrophotometry, Ultraviolet; Taurocholic Acid; Ursodeoxycholic Acid | 1996 |
Effect of endotoxin on bile acid transport in rat liver: a potential model for sepsis-associated cholestasis.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Bile Acids and Salts; Biological Transport; Cell Membrane; Cholestasis; Endotoxins; Immunoblotting; Infections; Liver; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Taurocholic Acid; Tissue Distribution; Tumor Necrosis Factor-alpha | 1996 |
More Na+/bile acid cotransporters in hepatocytes? Lessons from obstructive cholestasis.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Carrier Proteins; Cholestasis; Common Bile Duct; Ligation; Liver; Organic Anion Transporters, Sodium-Dependent; Rats; RNA, Messenger; Symporters; Taurocholic Acid | 1996 |
Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion.
Topics: Adenosine Triphosphate; Animals; Bile; Biological Transport; Cell Membrane; Cholestasis; Lipopolysaccharides; Liver; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Sepsis-associated cholestasis.
Topics: Adenosine Triphosphate; Bile; Biological Transport; Cell Membrane; Cholestasis; Humans; Sepsis; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Expression of the rat liver Na+/taurocholate cotransporter is regulated in vivo by retention of biliary constituents but not their depletion.
Topics: Animals; Biliary Fistula; Carrier Proteins; Cholestasis; Down-Regulation; Male; Organic Anion Transporters, Sodium-Dependent; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Symporters; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Differential interaction of bile acids from patients with inborn errors of bile acid synthesis with hepatocellular bile acid transporters.
Topics: Animals; Bile Acids and Salts; Biological Transport, Active; Carrier Proteins; Cholestasis; Humans; Lipid Metabolism, Inborn Errors; Liver; Male; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 1997 |
Effect of tauro-alpha-muricholate and tauro-beta-muricholate on oestradiol-17 beta-glucuronide-induced cholestasis in rats.
Topics: Animals; Cholestasis; Estradiol; Isomerism; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Effect of cholestasis on regulation of cAMP synthesis by glucagon and bile acids in isolated hepatocytes.
Topics: Angiotensin II; Animals; Bile; Bile Acids and Salts; Cells, Cultured; Cholestasis; Colforsin; Common Bile Duct; Cricetinae; Cyclic AMP; Glucagon; Isoenzymes; Kinetics; Liver; Male; Mesocricetus; Protein Kinase C; Protein Kinase C-alpha; Receptors, Glucagon; Reference Values; Taurocholic Acid; Ursodeoxycholic Acid | 1997 |
Identification and functional characterization of the promoter region of the human organic anion transporting polypeptide gene.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Base Sequence; Carrier Proteins; CHO Cells; Cholestasis; Cloning, Molecular; Cricetinae; Dogs; Gene Expression Regulation; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Taurocholic Acid; Tumor Cells, Cultured | 1997 |
Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat.
Topics: Alkaline Phosphatase; Animals; Calcium; Cholagogues and Choleretics; Cholestasis; Injections, Intravenous; L-Lactate Dehydrogenase; Liver; Phospholipids; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1998 |
The role of dietary choline in the beneficial effects of lecithin on the secretion of biliary lipids in rats.
Topics: Animals; Bile; Bile Acids and Salts; Bile Canaliculi; Cholestasis; Cholesterol; Choline; Diet; Energy Intake; Fatty Acids; Intracellular Membranes; Lipids; Liver; Male; Phosphatidylcholines; Phospholipids; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 1998 |
Neither intestinal sequestration of bile acids nor common bile duct ligation modulate the expression and function of the rat ileal bile acid transporter.
Topics: Allylamine; Animals; Bile Acids and Salts; Carrier Proteins; Cholagogues and Choleretics; Cholestasis; Colesevelam Hydrochloride; Common Bile Duct; Hydroxysteroid Dehydrogenases; Ileum; Intestinal Mucosa; Membrane Glycoproteins; Microvilli; Organic Anion Transporters, Sodium-Dependent; Rats; Rats, Sprague-Dawley; Symporters; Taurocholic Acid | 1998 |
Solubilization of liver alkaline phosphatase isoenzyme during cholestasis in dogs.
Topics: Alkaline Phosphatase; Animals; Antibodies, Monoclonal; Blotting, Western; Cholestasis; Chromatography, Affinity; Chromatography, Agarose; Dog Diseases; Dogs; Electrophoresis, Polyacrylamide Gel; Gas Chromatography-Mass Spectrometry; Glycosylphosphatidylinositols; Indicators and Reagents; Indoles; Inositol; Isoenzymes; Liver; Nitroblue Tetrazolium; Solubility; Taurocholic Acid | 1999 |
Bile salt independent flow during bile salt-induced choleresis and cholestasis in the rat: role of biliary thiol secretion.
Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts, Intrahepatic; Cholestasis; Glutathione; Male; Perfusion; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurolithocholic Acid | 2000 |
Mrp2 is essential for estradiol-17beta(beta-D-glucuronide)-induced cholestasis in rats.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cholestasis; Estradiol; Male; Multidrug Resistance-Associated Proteins; Rats; Rats, Sprague-Dawley; Rats, Wistar; Taurocholic Acid | 2000 |
The effect of oral sodium taurocholate on endotoxemia and intestinal anastomotic wound healing in rats with obstructive jaundice.
Topics: Anastomosis, Surgical; Animals; Cholestasis; Endotoxemia; Female; Hydroxyproline; Ileum; Intestines; Male; Rats; Rats, Wistar; Taurocholic Acid; Wound Healing | 1997 |
The bile acid taurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis.
Topics: Animals; Calcium; Cell Culture Techniques; Cell Death; Cholestasis; Disease Models, Animal; Female; Fetal Death; Fetal Heart; Humans; Maternal-Fetal Exchange; Myocardial Contraction; Pregnancy; Pregnancy Complications; Rats; Taurocholic Acid | 2001 |
Dapsone-induced cholestasis and impairment of bile salt output in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile Acids and Salts; Biomarkers; Body Weight; Carrier Proteins; Cholestasis; Dapsone; Disease Models, Animal; Female; Liver; Methemoglobinemia; Microvilli; Organ Size; Organic Anion Transporters, Sodium-Dependent; Rats; Rats, Wistar; Symporters; Taurocholic Acid | 2002 |
Effects of high taurocholate load on activities of hepatic alcohol metabolizing enzymes.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Animals; Catalase; Cholestasis; Cytochrome P-450 Enzyme System; Disease Models, Animal; Ethanol; Humans; Liver; Male; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 2002 |
An in vivo-in vitro comparison of the effects of bile acids on the structural organization and functional activity of liver microsomal monooxygenases.
Topics: Animals; Cholestasis; Cholic Acids; Cytochrome Reductases; Deoxycholic Acid; In Vitro Techniques; Lipid Metabolism; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxygenases; Rats; Taurocholic Acid; Taurodeoxycholic Acid | 1978 |
Choleresis and cholestasis produced by infusion of taurocholic acid or taurodehydrocholic acid combined with BSP in the rhesus monkey.
Topics: Animals; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Cholecystectomy; Cholestasis; Haplorhini; Liver; Macaca mulatta; Male; Sulfobromophthalein; Taurocholic Acid; Time Factors | 1979 |
Effects of chlorpromazine hydrochloride on bile salt synthesis, bile formation and biliary lipid secretion in the rhesus monkey: a model for chlorpromazine-induced cholestasis.
Topics: Animals; Bile; Bile Acids and Salts; Chlorpromazine; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Lipid Metabolism; Macaca mulatta; Taurocholic Acid | 1979 |
Bile salts, obstructive jaundice and renal blood flow.
Topics: Acute Kidney Injury; Animals; Bile Acids and Salts; Blood Vessels; Cholestasis; Haplorhini; Kidney; Norepinephrine; Papio; Rabbits; Regional Blood Flow; Taurocholic Acid | 1979 |
The effect of complete biliary obstruction on bile flow and bile acid excretion: postcholestatic choleresis in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Common Bile Duct; Erythritol; Liver; Male; Rats; Taurocholic Acid | 1979 |
Choleretic and cholestatic effects of infused bile salts in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Dose-Response Relationship, Drug; Male; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1979 |
Cholestatic steroid hormones inhibit taurocholate uptake into isolated rat hepatocytes.
Topics: Animals; Biological Transport; Cholestasis; Depression, Chemical; Estradiol; In Vitro Techniques; Kinetics; Liver; Male; Norethandrolone; Progesterone; Rats; Taurocholic Acid; Temperature | 1977 |
Endotoxin, bile salts and renal function in obstructive jaundice.
Topics: Acute Kidney Injury; Adult; Aged; Animals; Bile Acids and Salts; Bilirubin; Cholestasis; Creatinine; Endotoxins; Escherichia coli; Female; Humans; Male; Middle Aged; Rats; Taurocholic Acid | 1976 |
Taurolithocholate-induced cholestasis: taurocholate but not dehydrocholate, reverses cholestasis and bile canalicular membrane injury.
Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Cholestasis; Cholic Acids; Dehydrocholic Acid; Disease Models, Animal; Erythritol; Inulin; Lithocholic Acid; Liver; Liver Function Tests; Male; Microscopy, Electron, Scanning; Rats; Secretory Rate; Taurocholic Acid | 1977 |
Bile secretion in selective biliary obstruction. Adaptation of taurocholate transport maximum to increased secretory load in the rat.
Topics: Adaptation, Physiological; Animals; Bile; Bile Acids and Salts; Cholestasis; Cholesterol; Disease Models, Animal; Duodenum; Intubation, Gastrointestinal; Liver; Male; Phospholipids; Rats; Secretory Rate; Taurocholic Acid; Water | 1977 |
[Proceedings: Cholestatic effect of sodium taurocholate (Na-Tc) in the rat in vivo].
Topics: Animals; Bile Acids and Salts; Cholestasis; Gallbladder; Rats; Taurocholic Acid | 1976 |
Interaction of bile with erythromycin Lactobionate in vitro.
Topics: Bile; Chemical Phenomena; Chemistry; Cholestasis; Disaccharides; Emulsions; Erythrocytes; Erythromycin; Glycocholic Acid; Humans; In Vitro Techniques; Methanol; Sodium Chloride; Surface Tension; Taurocholic Acid | 1975 |
Effect of biliary stasis and hepatotoxins on the excretion of iopanoate in the rat.
Topics: Animals; Bile Ducts; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cholestasis; Glomerular Filtration Rate; Glucuronates; Iodine Radioisotopes; Iopanoic Acid; Kidney; Kinetics; Lithocholic Acid; Liver; Male; Naphthalenes; Proadifen; Rats; Taurocholic Acid; Thiocyanates | 1975 |
Scanning electron microscopy of the rat liver. Studies of the effect of taurolithocholate and other models of cholestasis.
Topics: Animals; Bile; Bile Ducts, Intrahepatic; Cholestasis; Dilatation, Pathologic; Disease Models, Animal; Ethinyl Estradiol; Female; Ligation; Lithocholic Acid; Liver; Male; Microscopy, Electron, Scanning; Rats; Secretory Rate; Taurocholic Acid | 1975 |
[Mechanisms of bile secretion in mini-pigs (author's transl)].
Topics: Animals; Bile; Bile Acids and Salts; Cholecystectomy; Cholecystokinin; Cholelithiasis; Cholestasis; Enterohepatic Circulation; Fasting; Gallbladder; Ioglycamic Acid; Phenobarbital; Secretin; Stimulation, Chemical; Swine; Taurocholic Acid | 1975 |
Microtubule-independent choleresis and anti-cholestatic action of tauroursodeoxycholate in colchicine-treated rat liver.
Topics: Animals; Aspartate Aminotransferases; Bile; Cholestasis; Colchicine; gamma-Glutamyltransferase; Male; Microtubules; Rats; Rats, Inbred Strains; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1992 |
Bile salt-associated electrolyte secretion. A study following a short-term biliary obstruction in the rat.
Topics: Animals; Bicarbonates; Bile; Bile Acids and Salts; Cholestasis; Disease Models, Animal; Male; Rats; Rats, Wistar; Sodium Chloride; Taurocholic Acid | 1992 |
Tauro-beta-muricholate preserves choleresis and prevents taurocholate-induced cholestasis in colchicine-treated rat liver.
Topics: Animals; Bicarbonates; Bile; Cholagogues and Choleretics; Cholestasis; Cholic Acids; Colchicine; In Vitro Techniques; Male; Phospholipids; Rats; Rats, Inbred Strains; Taurine; Taurocholic Acid | 1992 |
Effects of bile acids and bilirubin on bicarbonate secretion of isolated guinea pig antrum.
Topics: Animals; Bicarbonates; Bilirubin; Cholestasis; Cholic Acid; Cholic Acids; Guinea Pigs; In Vitro Techniques; Male; Pyloric Antrum; Stomach Ulcer; Taurocholic Acid | 1992 |
Effects of bile salt infusion on chlorpromazine-induced cholestasis in the isolated perfused rat liver.
Topics: Animals; Bile; Chlorpromazine; Cholestasis; In Vitro Techniques; Isomerism; Kinetics; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Time Factors | 1992 |
Cholestasis and changes of portal pressure caused by chlorpromazine in the perfused rat liver.
Topics: Animals; Bile; Blood Pressure; Chlorpromazine; Cholestasis; Cyclooxygenase Inhibitors; Indomethacin; L-Lactate Dehydrogenase; Liver; Male; Oxygen Consumption; Perfusion; Portal System; Prostaglandin D2; Rats; Rats, Inbred Strains; Taurocholic Acid | 1991 |
Estradiol-17 beta-D-glucuronide (E-17G) cholestasis in perfused rat liver: fate of E-17G and choleretic responses to bile salts.
Topics: Animals; Bile; Bile Acids and Salts; Biological Transport; Cholagogues and Choleretics; Cholestasis; Dehydrocholic Acid; Estradiol; Male; Rats; Rats, Inbred Strains; Sucrose; Taurochenodeoxycholic Acid; Taurocholic Acid | 1990 |
Formation of biliary thrombi in protoporphyrin-induced cholestasis in perfused rat liver.
Topics: Animals; Bile; Bile Acids and Salts; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Diseases; Microscopy, Electron; Perfusion; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid | 1990 |
Taurocholate-induced gastric damage in rats with obstructive jaundice.
Topics: Animals; Cholestasis; Electrophysiology; Gastric Mucosa; Hexosamines; Male; Osmolar Concentration; Rats; Stomach; Stomach Ulcer; Taurocholic Acid | 1989 |
The histoautoradiographic localization of taurocholate in rat liver after bile duct ligation. Evidence for ongoing secretion and reabsorption processes.
Topics: Animals; Autoradiography; Bile Ducts; Cholestasis; Ligation; Liver; Male; Rats; Rats, Inbred Strains; Taurocholic Acid | 1989 |
Early changes in bile secretion following relief of short-term biliary obstruction in the rat.
Topics: 5'-Nucleotidase; Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Cholestasis; Male; Nucleotidases; Rats; Rats, Inbred Strains; Taurocholic Acid | 1988 |
Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat.
Topics: 5'-Nucleotidase; Albumins; Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Isomerism; L-Lactate Dehydrogenase; Male; Nucleotidases; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Time Factors | 1985 |
Cholestasis and changes in the microcirculation of perfused rat liver caused by the calcium ionophore A23187 and type I antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Bile; Blood Pressure; Calcimycin; Cholestasis; Liver; Male; Microcirculation; Papaverine; Prajmaline; Quinidine; Rats; Rats, Inbred Strains; Taurocholic Acid | 1987 |
Prevention of endotoxaemia in obstructive jaundice--a comparative study of bile salts.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Deoxycholic Acid; Endotoxins; Escherichia coli; Glycodeoxycholic Acid; Intestinal Absorption; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Taurodeoxycholic Acid; Ursodeoxycholic Acid | 1988 |
Mechanisms of acute gastric mucosal lesion accompanying obstructive jaundice--role of bile acids in plasma.
Topics: Acute Disease; Animals; Bile Acids and Salts; Cholestasis; Gastric Acid; Gastric Mucosa; Hexosamines; Histocytochemistry; Liver; Male; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological; Taurocholic Acid | 1986 |
Taurocholate and steroid glucuronides: mutual protection against cholestasis in the isolated perfused rat liver.
Topics: Animals; Bile; Bile Acids and Salts; Biological Transport; Cholestasis; Dose-Response Relationship, Drug; Estradiol; Female; Perfusion; Rats; Rats, Inbred Strains; Sulfobromophthalein; Taurocholic Acid | 1986 |
[Experimental and clinical studies on the effects of supplemental administration of bile salts after relief of biliary obstruction].
Topics: Adult; Animals; Bile Acids and Salts; Bilirubin; Cholestasis; Cholestasis, Extrahepatic; Female; Humans; Male; Middle Aged; Rats; Rats, Inbred Strains; Taurocholic Acid | 1986 |
Sepsis and cholestasis: the in vitro effects of bacterial products on 14C-taurocholate uptake by isolated rat hepatocytes.
Topics: Animals; Bacterial Physiological Phenomena; Bile Acids and Salts; Cholestasis; Endotoxins; Gram-Negative Bacteria; Gram-Positive Bacteria; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Taurocholic Acid | 1986 |
Characterization of calcium deprivation-induced cholestasis in the perfused rat liver.
Topics: Animals; Bile; Biological Transport; Calcium; Cholestasis; In Vitro Techniques; Intercellular Junctions; Liver; Male; Perfusion; Permeability; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Sucrose; Taurocholic Acid | 1985 |
Enhancement of the urinary excretion of non-sulphated and sulphated radioactive bile acids by sodium acetate in the bile duct obstructed rat.
Topics: Acetates; Acetic Acid; Animals; Bile Acids and Salts; Cholestasis; Glomerular Filtration Rate; Glycochenodeoxycholic Acid; Glycocholic Acid; Kidney Function Tests; Male; Probenecid; Protein Binding; Rats; Rats, Inbred Strains; Stimulation, Chemical; Taurocholic Acid; Urodynamics | 1985 |
Biliary permeability during ethinyl estradiol-induced cholestasis studied by segmented retrograde intrabiliary injections in rats.
Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts; Carbon Radioisotopes; Cholestasis; Ethinyl Estradiol; Glycocholic Acid; Histamine; Injections; Inulin; Iodine Radioisotopes; Male; Permeability; Rats; Rats, Inbred Strains; Sucrose; Taurocholic Acid | 1985 |
Mechanism of liver mitochondrial dysfunction associated with bile duct obstruction.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Bilirubin; Cholestasis; Male; Mitochondria, Liver; Phospholipids; Rats; Rats, Inbred Strains; Taurocholic Acid; Ubiquinone | 1985 |
[Cytochrome P-450-dependent 6a-hydroxylation of taurolitho-cholic acid in man].
Topics: Cholestasis; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Microsomes, Liver; Taurocholic Acid | 1974 |
Bile acid formation by liver microsomal systems.
Topics: Animals; Bile Acids and Salts; Cholestasis; Cholic Acids; Cytochrome P-450 Enzyme System; Deoxycholic Acid; Hydroxylation; Microsomes, Liver; Rats; Taurocholic Acid | 1973 |
Sulfated and nonsulfated bile acid in human serum.
Topics: Adult; Aged; Bile Acids and Salts; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gel; Chromatography, Ion Exchange; Deoxycholic Acid; Female; Glycocholic Acid; Humans; Liver Diseases; Liver Function Tests; Male; Middle Aged; Sulfuric Acids; Taurocholic Acid | 1972 |
Effect of taurocholate, dehydrocholate and secretin on biliary output of alkaline phosphatase and GOT.
Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bile; Cholelithiasis; Cholestasis; Dehydrocholic Acid; Female; Humans; Injections, Intravenous; Middle Aged; Secretin; Secretory Rate; Stimulation, Chemical; Taurocholic Acid | 1973 |
Impaired jejunal transport of monosaccharides in experimental cholestasis.
Topics: Animals; Bile Ducts; Carbon Radioisotopes; Cholestasis; Glucose; In Vitro Techniques; Jejunum; Ligation; Male; Methylglycosides; Rats; Taurocholic Acid | 1973 |
[Formation of bile acid sulfate esters in perfused rat livers following bile duct occlusion].
Topics: Animals; Bile Acids and Salts; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Esters; Lithocholic Acid; Liver; Male; Perfusion; Rats; Sulfates; Taurocholic Acid | 1974 |