Page last updated: 2024-10-20

taurine and Reperfusion Injury

taurine has been researched along with Reperfusion Injury in 73 studies

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"As a non-toxic endogenous antioxidant, the semi-essential amino acid taurine is a potential attenuator of oxidative damage such as that produced by ischaemia-reperfusion injury."8.82The therapeutic role of taurine in ischaemia-reperfusion injury. ( Kelly, CJ; Kingston, R; Murray, P, 2004)
"Taurine is reported to reduce tissue damage induced by inflammation and to protect the brain against experimental stroke."7.78Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB. ( Gu, Y; Sun, M; Xu, C; Zhao, Y, 2012)
"This study shows that preconditioning with taurine or glycine is equally effective in preventing injury to fatty livers most likely via Kupffer cell-dependent mechanisms."7.77Glycine and taurine equally prevent fatty livers from Kupffer cell-dependent injury: an in vivo microscopy study. ( Bruns, H; Büchler, MW; Flechtenmacher, C; Galli, U; Gebhard, MM; Schemmer, P; Schulze-Bergkamen, H; Watanpour, I; Zorn, M, 2011)
"Our results suggest that taurine attenuates endoplasmic reticulum stress-induced apoptosis in the lungs of rats after limb ischemia reperfusion."7.76Taurine protects against lung damage following limb ischemia reperfusion in the rat by attenuating endoplasmic reticulum stress-induced apoptosis. ( Cao, G; Gao, J; Han, S; Lu, H; Men, X; Pu, J; Yu, H; Zhang, L, 2010)
"To investigate the effect of pretreatment with taurine on liver injury changes and the change of tumor necrosis factor alpha and NFkappaB expression following rats limbs ischemia/reperfusion."7.75[Effects of taurine on TNF-alpha and NF-kappaB expression of liver injury after limbs ischemia/reperfusion in rats]. ( Dong, SY; Kong, XY; Wang, YH; Zhang, LY; Zhang, N; Zhao, LJ, 2009)
"To evaluate the effect of taurine, a potent antioxidant, on testicular ischemia-reperfusion injury due to excess reactive oxygen species produced by neutrophils after testicular torsion-detorsion."7.74Beneficial effect of taurine on testicular ischemia-reperfusion injury in rats. ( Wei, SM; Yan, ZZ; Zhou, J, 2007)
"Preservation of fast twitch strength following ischaemia-reperfusion injury by administration of taurine before ischaemia has clinical potential."7.73Effects of systemic and regional taurine on skeletal muscle function following ischaemia-reperfusion injury. ( Kearns, S; Kelly, C; Kingston, R; Murray, P, 2005)
"The data show that taurine protects livers from ischemia-reoxygenation."7.70Taurine attenuates cold ischemia-reoxygenation injury in rat liver. ( Häussinger, D; Wettstein, M, 2000)
"These data show that pharmaceutical use of the endogenous amino acid taurine, unlike many-other agents, protects electrophysiological function in skeletal muscle against both early and late ischaemia-reperfusion injury."7.70Taurine protects against early and late skeletal muscle dysfunction secondary to ischaemia reperfusion injury. ( Bouchier-Hayes, D; Bowler, D; Kay, E; Kelly, CJ; McLaughlin, R, 2000)
" Ouabain and monensin mimicked reperfusion injury and their toxicity was also reduced by taurine."7.69Protective effect of taurine against reperfusion injury in cultured rat astrocytes. ( Azuma, J; Baba, A; Kishida, Y; Matsuda, T; Takuma, K, 1996)
"The protective effect of taurine on ischemia-reperfusion damages of rat perfused liver and its possible mechanism were investigated."7.68[Protective action of taurine on ischemia-reperfusion liver injury in rats and its mechanism]. ( Chen, YX, 1993)
"Taurine was administered 45 min prior to induction of ischemia."5.46Protective effects of taurine against renal ischemia/reperfusion injury in rats by inhibition of gelatinases, MMP-2 and MMP-9, and p38 mitogen-activated protein kinase signaling. ( Akdogan, G; Arslan, S; Camsari, T; Cavdar, Z; Celik, A; Ergur, UB; Guneli, E; Ozbal, S; Terzioglu, G; Ural, C; Yildiz, S, 2017)
"Taurine (TAU) is a sulfur-containing amino acid that is involved in a diverse array of biological and physiological functions, including bile salt conjugation, osmoregulation, membrane stabilization, calcium modulation, anti-oxidation, and immunomodulation."5.43Effect of taurine on intestinal recovery following intestinal ischemia-reperfusion injury in a rat. ( Aranovich, I; Ben Shahar, Y; Berkowitz, D; Bitterman, A; Bitterman, N; Chepurov, D; Coran, AG; Pollak, Y; Sukhotnik, I, 2016)
"Taurine is an organic acid, which has a very important function in the human body."5.37Effects of taurine on reperfusion injury. ( Akdemir, O; Arslan, Z; Hede, Y; Lineaweaver, WC; Songur, E; Zhang, F, 2011)
"Taurine is an endogenous antioxidant and a membrane-stabilizing, intracellular, free beta-amino acid."5.34The effect of taurine on renal ischemia/reperfusion injury. ( Demirogullari, B; Guz, G; Karasu, C; Lortlar, N; Nurlu, N; Omeroglu, S; Oz, E; Sert, S; Ulusu, NN, 2007)
"Ischemia-reperfusion injury is of major clinical relevance during liver transplantation."5.33Taurine protects against ischemia-reperfusion injury in rabbit livers. ( Jiang, H; Li, J; Meng, F; Qiao, H; Sun, X; Tong, L, 2006)
"NO may play an important role in lung injury induced by shock/reperfusion."5.32[Relationship between lung injury induced by hemorrhagic shock/reperfusion and nitric oxide and beneficial effect of taurine]. ( Chu, CJ; Deng, FM; He, F; Sun, ZP; Zhong, H, 2004)
"taurine (200 mg/kg) was intravenously injected 5 min before heart ischemia."5.32[Effects of taurine on rabbit cardiomyocyte apoptosis during ischemia/reperfusion injury]. ( Ji, ES; Li, AY; Li, Q; Ma, ZH; Zhao, SM, 2004)
"As a non-toxic endogenous antioxidant, the semi-essential amino acid taurine is a potential attenuator of oxidative damage such as that produced by ischaemia-reperfusion injury."4.82The therapeutic role of taurine in ischaemia-reperfusion injury. ( Kelly, CJ; Kingston, R; Murray, P, 2004)
" The effects of USC-Exo on ferroptosis and lncRNA taurine-upregulated gene 1 (TUG1) were detected in hypoxia/reoxygenation (H/R)-treated human proximal tubular epithelial cells (HK-2)."4.12Exosomal lncRNA TUG1 derived from human urine-derived stem cells attenuates renal ischemia/reperfusion injury by interacting with SRSF1 to regulate ASCL4-mediated ferroptosis. ( Bi, Q; Sun, Z; Wang, W; Wu, J, 2022)
"Emerging evidence has suggested that hydrogen sulfide (H2S) may alleviate the cellular damage associated with cerebral ischemia/reperfusion (I/R) injury."3.85The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model. ( Choi, CG; Choi, Y; Ha, HK; Ham, SJ; Jeon, SB; Jung, SC; Kim, J; Kim, JK; Kim, KW; Kim, ST; Kwon, JI; Shim, WH; Sung, YS; Woo, CW; Woo, DC, 2017)
"Taurine is reported to reduce tissue damage induced by inflammation and to protect the brain against experimental stroke."3.78Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB. ( Gu, Y; Sun, M; Xu, C; Zhao, Y, 2012)
"This study shows that preconditioning with taurine or glycine is equally effective in preventing injury to fatty livers most likely via Kupffer cell-dependent mechanisms."3.77Glycine and taurine equally prevent fatty livers from Kupffer cell-dependent injury: an in vivo microscopy study. ( Bruns, H; Büchler, MW; Flechtenmacher, C; Galli, U; Gebhard, MM; Schemmer, P; Schulze-Bergkamen, H; Watanpour, I; Zorn, M, 2011)
"Our results suggest that taurine attenuates endoplasmic reticulum stress-induced apoptosis in the lungs of rats after limb ischemia reperfusion."3.76Taurine protects against lung damage following limb ischemia reperfusion in the rat by attenuating endoplasmic reticulum stress-induced apoptosis. ( Cao, G; Gao, J; Han, S; Lu, H; Men, X; Pu, J; Yu, H; Zhang, L, 2010)
"To investigate the effect of pretreatment with taurine on liver injury changes and the change of tumor necrosis factor alpha and NFkappaB expression following rats limbs ischemia/reperfusion."3.75[Effects of taurine on TNF-alpha and NF-kappaB expression of liver injury after limbs ischemia/reperfusion in rats]. ( Dong, SY; Kong, XY; Wang, YH; Zhang, LY; Zhang, N; Zhao, LJ, 2009)
"To evaluate the effect of taurine, a potent antioxidant, on testicular ischemia-reperfusion injury due to excess reactive oxygen species produced by neutrophils after testicular torsion-detorsion."3.74Beneficial effect of taurine on testicular ischemia-reperfusion injury in rats. ( Wei, SM; Yan, ZZ; Zhou, J, 2007)
"This study demonstrates that donor preconditioning with taurine protects kidney grafts from injury (apoptosis, necrosis), improves graft function, and increases the regenerative potential most likely via mechanisms including antioxidation."3.74Donor preconditioning with taurine protects kidney grafts from injury after experimental transplantation. ( Büchler, MW; Dei-Anane, G; Gross, ML; Guan, X; Kern, M; Liang, R; Ludwig, J; Nickkholgh, A; Schemmer, P; Schmidt, J; Zeier, M, 2008)
"Preservation of fast twitch strength following ischaemia-reperfusion injury by administration of taurine before ischaemia has clinical potential."3.73Effects of systemic and regional taurine on skeletal muscle function following ischaemia-reperfusion injury. ( Kearns, S; Kelly, C; Kingston, R; Murray, P, 2005)
"An experimental comparative study on isolated guinea pig-lungs has been undertaken to determine the probable beneficial effects of adding taurine to pulmonary reperfusion solutions in lung ischemia-reperfusion."3.71The role of taurine added to pulmonary reperfusion solutions in isolated guinea pig lungs. ( Altunkaya, A; Halit, V; Oz, E; Sivrikoz, MC; Take, G, 2002)
"We examined the effect of ellagic acid (EA), one of the polyphenols that are abundantly contained in whisky as a nonalcoholic component, on gastric lesions induced by ammonia plus ischemia or ischemia/reperfusion in rats, in relation to the antioxidative system."3.71Effect of ellagic acid on gastric damage induced in ischemic rat stomachs following ammonia or reperfusion. ( Iino, T; Ogawa, Y; Takata, K; Takeeda, M; Takeuchi, K; Tashima, K; Umeda, M, 2002)
"The data show that taurine protects livers from ischemia-reoxygenation."3.70Taurine attenuates cold ischemia-reoxygenation injury in rat liver. ( Häussinger, D; Wettstein, M, 2000)
"These data show that pharmaceutical use of the endogenous amino acid taurine, unlike many-other agents, protects electrophysiological function in skeletal muscle against both early and late ischaemia-reperfusion injury."3.70Taurine protects against early and late skeletal muscle dysfunction secondary to ischaemia reperfusion injury. ( Bouchier-Hayes, D; Bowler, D; Kay, E; Kelly, CJ; McLaughlin, R, 2000)
" Ouabain and monensin mimicked reperfusion injury and their toxicity was also reduced by taurine."3.69Protective effect of taurine against reperfusion injury in cultured rat astrocytes. ( Azuma, J; Baba, A; Kishida, Y; Matsuda, T; Takuma, K, 1996)
"The protective effect of taurine on ischemia-reperfusion damages of rat perfused liver and its possible mechanism were investigated."3.68[Protective action of taurine on ischemia-reperfusion liver injury in rats and its mechanism]. ( Chen, YX, 1993)
"Glycine has been well characterized in spinal cord as an inhibitory neurotransmitter which activates a glycine-gated chloride channel (GlyR) expressed in postsynaptic membranes."2.40Glycine: a new anti-inflammatory immunonutrient. ( Bradford, B; Enomoto, N; Ikejema, K; Rose, ML; Rusyn, I; Schemmer, P; Seabra, V; Stacklewitz, RF; Thurman, RG; Wheeler, MD; Yin, M; Zhong, Z, 1999)
"Icaritin (ICT) has been previously demonstrated to display protective effects against cerebral ischemic reperfusion (I/R) by inhibiting oxidative stress, but the mechanism remains unclear."1.91UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion. ( Feng, Z; Liu, Z; Sun, C; Sun, L; Tang, Y; Yao, J; Zhang, G; Zhao, Y, 2023)
"Taurine was administered 45 min prior to induction of ischemia."1.46Protective effects of taurine against renal ischemia/reperfusion injury in rats by inhibition of gelatinases, MMP-2 and MMP-9, and p38 mitogen-activated protein kinase signaling. ( Akdogan, G; Arslan, S; Camsari, T; Cavdar, Z; Celik, A; Ergur, UB; Guneli, E; Ozbal, S; Terzioglu, G; Ural, C; Yildiz, S, 2017)
"Taurine (TAU) is a sulfur-containing amino acid that is involved in a diverse array of biological and physiological functions, including bile salt conjugation, osmoregulation, membrane stabilization, calcium modulation, anti-oxidation, and immunomodulation."1.43Effect of taurine on intestinal recovery following intestinal ischemia-reperfusion injury in a rat. ( Aranovich, I; Ben Shahar, Y; Berkowitz, D; Bitterman, A; Bitterman, N; Chepurov, D; Coran, AG; Pollak, Y; Sukhotnik, I, 2016)
"Those that developed cerebral ischemia after MCAO were randomized to receive propylene glycol salt water and ligustrazine respectively."1.40Effect of ligustrazine on levels of amino acid neurotransmitters in rat striatum after cerebral ischemia-reperfusion injury. ( Bie, XD; Ge, LJ; Han, J; Wan, HT; Yang, JH; Zhang, YY, 2014)
"Taurine is an organic acid, which has a very important function in the human body."1.37Effects of taurine on reperfusion injury. ( Akdemir, O; Arslan, Z; Hede, Y; Lineaweaver, WC; Songur, E; Zhang, F, 2011)
"Taurine has been shown to protect organs from ischemia reperfusion or endotoxin by its anti-oxidant and anti-inflammatory activities."1.36Protective effects of taurine against endotoxin-induced acute liver injury after hepatic ischemia reperfusion. ( Chen, X; Jiang, H; Mao, Y; Qiao, H; Sun, X; Tong, L; Zhang, F; Zhao, H, 2010)
"Ischemia/reperfusion injury is mediated by various mechanisms."1.35Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury. ( Backhaus, J; Büchler, MW; Flechtenmacher, C; Gebhard, MM; Kincius, M; Liang, R; Schemmer, P; Schindler, G; Zorn, M, 2009)
"Taurine was intravenously injected to Wistar rats 30 min before II/R; physiological saline and sham operation served as controls."1.35Taurine attenuates multiple organ injury induced by intestinal ischemia reperfusion in rats. ( Dong, X; Jiang, H; Qiao, G; Qiao, H; Sun, X; Tong, L; Zhang, F, 2008)
"Taurine is an endogenous antioxidant and a membrane-stabilizing, intracellular, free beta-amino acid."1.34The effect of taurine on renal ischemia/reperfusion injury. ( Demirogullari, B; Guz, G; Karasu, C; Lortlar, N; Nurlu, N; Omeroglu, S; Oz, E; Sert, S; Ulusu, NN, 2007)
"Ischemia-reperfusion injury is of major clinical relevance during liver transplantation."1.33Taurine protects against ischemia-reperfusion injury in rabbit livers. ( Jiang, H; Li, J; Meng, F; Qiao, H; Sun, X; Tong, L, 2006)
"In taurine-treated animals, at 2h reperfusion, the mean arterial blood pressure and heart rate were increased, by 6% and 10%."1.33Taurine inhibits ischemia/reperfusion-induced compartment syndrome in rabbits. ( Li, Y; Pang, YZ; Tang, CS; Wang, JX; Zhang, J; Zhang, LK; Zhao, J, 2005)
" Compared with the model group, the concentration of Glu in the middle and large dosage groups of TGF, during the 120 min of ischemia, reduced by 38."1.32[Effects of tianma gouteng fang on transmitter amino acids in the hippocampus extracellular liquids in freely moving rats subjected to brain ischemia]. ( Du, GY; Sun, XF; Wang, DQ; Wang, W; Ye, ZG; Zhang, CY; Zhao, DZ, 2004)
"NO may play an important role in lung injury induced by shock/reperfusion."1.32[Relationship between lung injury induced by hemorrhagic shock/reperfusion and nitric oxide and beneficial effect of taurine]. ( Chu, CJ; Deng, FM; He, F; Sun, ZP; Zhong, H, 2004)
"taurine (200 mg/kg) was intravenously injected 5 min before heart ischemia."1.32[Effects of taurine on rabbit cardiomyocyte apoptosis during ischemia/reperfusion injury]. ( Ji, ES; Li, AY; Li, Q; Ma, ZH; Zhao, SM, 2004)
"Taurine (4% solution) was administrated orally for 48 h prior to the experiment."1.30Differential effects of lower limb revascularisation on organ injury and the role of the amino acid taurine. ( Abdih, H; Barry, MC; Hayes, DB; Kelly, CJ; Redmond, HP; Sheehan, SJ; Stapleton, P; Watson, RW, 1997)
"Like taurine, there were no significant changes in the intracellular concentration of ATP after ischaemia in the two groups of patients (from 3."1.30Warm blood cardioplegia reduces the fall in the intracellular concentration of taurine in the ischaemic/reperfused heart of patients undergoing aortic valve surgery. ( Angelini, GD; Ascione, R; Bryan, AJ; Gomes, WJ; Suleiman, MS, 1998)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (20.55)18.2507
2000's34 (46.58)29.6817
2010's21 (28.77)24.3611
2020's3 (4.11)2.80

Authors

AuthorsStudies
Sun, Z1
Wu, J1
Bi, Q1
Wang, W2
Tang, Y1
Sun, L1
Zhao, Y2
Yao, J1
Feng, Z1
Liu, Z1
Zhang, G1
Sun, C1
Qiu, S1
Li, X1
Zhang, J2
Shi, P1
Cao, Y1
Zhuang, Y1
Tong, L4
Kulthinee, S2
Wyss, JM2
Roysommuti, S2
Cavdar, Z1
Ural, C1
Celik, A1
Arslan, S1
Terzioglu, G1
Ozbal, S1
Yildiz, S1
Ergur, UB1
Guneli, E1
Camsari, T1
Akdogan, G1
Woo, CW1
Kwon, JI1
Kim, KW1
Kim, JK1
Jeon, SB1
Jung, SC1
Choi, CG1
Kim, ST1
Kim, J1
Ham, SJ1
Shim, WH1
Sung, YS1
Ha, HK1
Choi, Y1
Woo, DC1
Chen, L1
Chao, Y1
Cheng, P1
Li, N1
Zheng, H1
Yang, Y1
Guler, L1
Tavlasoglu, M1
Yucel, O1
Guler, A1
Sahin, MA1
Kurkluoglu, M1
Sirin, Y1
Eken, A1
Gamsizkan, M1
Dakak, M1
Gurkok, S1
Genc, O1
Rukan, TA1
Mksimovich, NE1
Zimatkin, SM1
Han, J1
Wan, HT1
Yang, JH1
Zhang, YY1
Ge, LJ1
Bie, XD1
Aydos, TR1
Başar, MM1
Kul, O1
Atmaca, HT1
Uzunalıoğlu, T1
Kisa, Ü1
Efe, OE1
Sukhotnik, I1
Aranovich, I1
Ben Shahar, Y1
Bitterman, N1
Pollak, Y1
Berkowitz, D1
Chepurov, D1
Coran, AG1
Bitterman, A1
Zhang, F3
Qiao, H3
Dong, X1
Qiao, G1
Jiang, H3
Sun, X3
Mao, Y1
Zhao, H1
Chen, X1
Schindler, G1
Kincius, M2
Liang, R3
Backhaus, J1
Zorn, M2
Flechtenmacher, C3
Gebhard, MM3
Büchler, MW4
Schemmer, P5
Ricci, L2
Valoti, M3
Sgaragli, G3
Frosini, M2
Men, X1
Han, S1
Gao, J1
Cao, G1
Zhang, L1
Yu, H1
Lu, H1
Pu, J1
Doddakula, KK1
Neary, PM1
Wang, JH1
Sookhai, S1
O'Donnell, A1
Aherne, T1
Bouchier-Hayes, DJ1
Redmond, HP2
Jirakulsomchok, D1
Mozaffari, MS1
Abdelsayed, R1
Patel, C1
Wimborne, H1
Liu, JY1
Schaffer, SW1
Chesney, RW1
Han, X1
Patters, AB1
He, F1
Sun, ZP1
Deng, FM1
Zhong, H1
Chu, CJ1
Bruns, H1
Watanpour, I1
Galli, U1
Schulze-Bergkamen, H1
Men, SL1
Xiong, JX1
Li, HJ1
Zhang, N1
Zhang, LY2
Wang, YH1
Dong, SY2
Kong, XY1
Zhao, LJ1
Li, AY1
Ji, ES1
Zhao, SM1
Ma, ZH1
Li, Q1
Men, XL1
Sun, SX1
Zhang, YB1
Akdemir, O1
Hede, Y1
Lineaweaver, WC1
Arslan, Z1
Songur, E1
Sun, M1
Gu, Y1
Xu, C1
Kirov, A1
Duarte, M1
Guay, J1
Karolak, M1
Yan, C1
Oxburgh, L1
Prudovsky, I1
Abbasoğlu, L1
Kalaz, EB1
Soluk-Tekkeşin, M1
Olgaç, V1
Doğru-Abbasoğlu, S1
Uysal, M1
Nanobashvili, J1
Neumayer, C1
Fügl, A1
Punz, A1
Blumer, R1
Prager, M1
Mittlböck, M1
Gruber, H1
Polterauer, P1
Roth, E1
Malinski, T1
Huk, I1
Michalk, DV1
Hoffmann, B1
Minor, T2
Melis, GC1
ter Wengel, N1
Boelens, PG1
van Leeuwen, PA1
Kingston, R2
Kelly, CJ3
Murray, P2
Büyükuysal, RL1
Kavianipour, M1
Wikström, G2
Ronquist, G2
Waldenström, A2
Zhang, CY1
Du, GY1
Ye, ZG1
Wang, DQ1
Sun, XF1
Zhao, DZ1
Kearns, S1
Kelly, C1
Wang, JX1
Li, Y1
Zhang, LK1
Zhao, J1
Pang, YZ1
Tang, CS1
Li, J1
Meng, F1
Guz, G1
Oz, E3
Lortlar, N1
Ulusu, NN1
Nurlu, N1
Demirogullari, B1
Omeroglu, S1
Sert, S1
Karasu, C1
Nickkholgh, A2
Hoffmann, K1
Ryschich, E1
Gutt, CN1
Schmidt, J2
Guan, X1
Dei-Anane, G1
Gross, ML1
Kern, M1
Ludwig, J1
Zeier, M1
Wei, SM2
Yan, ZZ2
Zhou, J2
Namazi, H1
Chen, YX1
Matsumoto, K1
Lo, EH1
Pierce, AR1
Halpern, EF1
Newcomb, R1
Yamaguchi, T1
Klauke, H1
Wingenfeld, P1
Michalk, D1
Isselhard, W1
Matsuda, T1
Takuma, K1
Kishida, Y1
Azuma, J1
Baba, A1
Delbarre, B1
Delbarre, G1
Calinon, F1
Barry, MC1
Abdih, H1
Watson, RW1
Stapleton, P1
Sheehan, SJ1
Hayes, DB1
Wettstein, M2
Häussinger, D2
Yoshida, WB1
Alasio, T1
Mazziotta, R1
Qin, F1
Kashani, M1
Lee, S1
Dardik, H1
Becker, R1
Kimelberg, HK1
Mongin, AA1
Ascione, R1
Gomes, WJ1
Angelini, GD1
Bryan, AJ1
Suleiman, MS1
Erbaş, D1
Gelir, E1
Aricioğlu, A1
Phillis, JW4
Song, D2
Guyot, LL3
O'Regan, MH4
Diaz, FG2
Cañas, PE1
Ren, J2
McLaughlin, R1
Bowler, D1
Kay, E1
Bouchier-Hayes, D1
Miyamoto, TA1
Miyamoto, KJ1
Wheeler, MD1
Ikejema, K1
Enomoto, N1
Stacklewitz, RF1
Seabra, V1
Zhong, Z1
Yin, M1
Rose, ML1
Rusyn, I1
Bradford, B1
Thurman, RG1
Zemgulis, V1
Bjerner, T1
Henze, A1
Thelin, S1
Pessina, F1
Matteucci, G1
Esposito, L1
Gorelli, B1
Iino, T1
Tashima, K1
Umeda, M1
Ogawa, Y1
Takeeda, M1
Takata, K1
Takeuchi, K1
Sivrikoz, MC1
Halit, V1
Altunkaya, A1
Take, G1
Zhou, M1
Ma, T1
Tseng, MT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Capability of a Glycine Oral Supplement for Diminishing Bronchial Inflammation in Children With Cystic Fibrosis[NCT01417481]Phase 213 participants (Actual)Interventional2012-03-31Terminated (stopped due to Some of the researchers finished their participation in the study.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Changes in Serum Concentration of Inflammatory Biomarkers (TNF-alpha)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentages were log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

Interventionlog (percent change) (Mean)
Glycine-0.3908
Placebo0.2035

Changes in Sputum Concentration of Inflammatory Biomarkers (G-CSF)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentage change was log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

Interventionlog (percent change) (Mean)
Glycine-0.0819
Placebo0.1668

Changes in Sputum Concentration of Inflammatory Biomarkers (IL-6)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentage change was log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

Interventionlog (percent change) (Mean)
Glycine-0.00007
Placebo0.1739

Changes in Clinical Data Scores (Other Than Sputum Production, Dyspnea and Global Symptoms)

"To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]).~Each respiratory symptom (Cough severity, Sputum features, Appetite, Dyspnea, and Energy perception) was evaluated in a 5-options Likert scale, ranging from 1 (better) to 5 (worse). The total score was computed by the simple sum of the five symptoms." (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Cough questionnaire scoreAppetite questionnaire scoreEnergy questionnaire scoreBody weightHeightHeart rateRespiratory rateTemperature
Glycine81.189.184.6101.6100.5103.594.8100.0
Placebo89.1132.1111.5103.6100.598.1109.0100.1

Changes in FEV1, FEF25, and FEFmax

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Forced expiratory volume at first second (FEV1)Forced expiratory flow at 25%FVC (FEF25)Maximal forced expiratory flow (FEFmax, PEFR)
Glycine109.7133.9115.3
Placebo91.483.391.2

Changes in Other Spirometric Variables

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Forced vital capacity (FVC)Forced expiratory flow at 75%FVC (FEF75)
Glycine104.1111.8
Placebo100.6108.9

Changes in Pulse Oximetry, FEV1/FVC, and FEF50.

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Peripheral oxygen saturation (SpO2)FEV1/FVCForced expiratory flow at 50%FVC (FEF50)
Glycine105.2105.2115.5
Placebo98.994.993.1

Changes in Score for Sputum Production, Dyspnea and Global Symptoms

"To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]).~In the symptoms questionnaire, each respiratory symptom (Cough severity, Sputum features, Appetite, Dyspnea, and Energy perception) was evaluated in a 5-options Likert scale, ranging from 1 (better) to 5 (worse). The total score was computed by the simple sum of the five symptoms." (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Sputum questionnaire scoreDyspnea questionnaire scoreTotal questionnaire score
Glycine82.075.677.7
Placebo102.6103.898.7

Changes in Serum Concentration of Inflammatory Biomarkers (Other Than TNF-alpha)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentages were log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

,
Interventionlog (percent change) (Mean)
MyeloperoxidaseIL-1IL-4IL-6IL-7IL-8IL-12IL-13G-CSFIFN-gammaMCP-1MIP-1beta
Glycine-0.4361-0.16350.29640.00850.0356-0.14660.3203-0.0561-0.07760.3272-0.08360.0330
Placebo-0.2906-0.03520.14700.22550.0819-0.23640.26030.19530.22720.36390.0472-0.0608

Changes in Sputum Concentration of Inflammatory Biomarkers (Other Than IL-6 and G-CSF)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentage change was log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

,
Interventionlog (percent change) (Mean)
MyeloperoxidaseIL-1IL-2IL-4IL-5IL-7IL-8IL-10IL-12IL-13IL-17IFN-gammaMCP-1MIP-1betaTNF-alphaGM-CSF
Glycine0.1294-0.09180.0233-0.01610.24980.0611-0.08240.05490.16750.16300.06800.02480.0042-0.03030.0412-0.0538
Placebo0.0669-0.0102-0.02740.05220.13040.13870.05420.00740.06770.09530.11400.06490.26080.09770.1568-0.0822

Reviews

6 reviews available for taurine and Reperfusion Injury

ArticleYear
Taurine and the renal system.
    Journal of biomedical science, 2010, Aug-24, Volume: 17 Suppl 1

    Topics: Animals; Apoptosis; Cell Cycle; Humans; Ions; Kidney; Kidney Diseases; Kidney Glomerulus; Osmolar Co

2010
Glutamine: recent developments in research on the clinical significance of glutamine.
    Current opinion in clinical nutrition and metabolic care, 2004, Volume: 7, Issue:1

    Topics: Animals; Clinical Trials as Topic; Dietary Supplements; Glutamine; Glutathione; Humans; Intestinal M

2004
The therapeutic role of taurine in ischaemia-reperfusion injury.
    Current pharmaceutical design, 2004, Volume: 10, Issue:19

    Topics: Animals; Antioxidants; Ascorbic Acid; Clinical Trials as Topic; Disease Models, Animal; Free Radical

2004
Swelling-activated release of excitatory amino acids in the brain: relevance for pathophysiology.
    Contributions to nephrology, 1998, Volume: 123

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1998
The role of xanthine oxidase and the effects of antioxidants in ischemia reperfusion cell injury.
    Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia, 1999, Volume: 49, Issue:1

    Topics: Antioxidants; Enzyme Inhibitors; Free Radicals; Humans; Ischemia; Neutrophils; Reactive Oxygen Speci

1999
Glycine: a new anti-inflammatory immunonutrient.
    Cellular and molecular life sciences : CMLS, 1999, Nov-30, Volume: 56, Issue:9-10

    Topics: Alcohols; Animals; Anti-Inflammatory Agents; Calcium Channels, L-Type; Chloride Channels; Cyclospori

1999

Trials

1 trial available for taurine and Reperfusion Injury

ArticleYear
The antiendotoxin agent taurolidine potentially reduces ischemia/reperfusion injury through its metabolite taurine.
    Surgery, 2010, Volume: 148, Issue:3

    Topics: Aged; Antioxidants; Cardiopulmonary Bypass; Constriction; Coronary Artery Bypass; Endotoxins; Female

2010

Other Studies

66 other studies available for taurine and Reperfusion Injury

ArticleYear
Exosomal lncRNA TUG1 derived from human urine-derived stem cells attenuates renal ischemia/reperfusion injury by interacting with SRSF1 to regulate ASCL4-mediated ferroptosis.
    Stem cell research & therapy, 2022, 07-15, Volume: 13, Issue:1

    Topics: Acute Kidney Injury; Animals; Ferroptosis; Humans; Hypoxia; Ischemia; Kidney; Mice; Mice, Inbred C57

2022
UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion.
    PeerJ, 2023, Volume: 11

    Topics: Animals; Antioxidants; Arachidonic Acid; Chromatography, High Pressure Liquid; gamma-Aminobutyric Ac

2023
Neutrophil membrane-coated taurine nanoparticles protect against hepatic ischemia-reperfusion injury.
    European journal of pharmacology, 2023, Jun-15, Volume: 949

    Topics: Glutathione; Humans; Interleukin-6; Liver; Liver Diseases; Neutrophils; Oxidative Stress; Reperfusio

2023
Taurine Supplementation Inhibits Cardiac and Systemic Renin-Angiotensin System Overactivity After Cardiac Ischemia/Reperfusion in Adult Female Rats Perinatally Depleted of Taurine Followed by High Sugar Intake.
    Advances in experimental medicine and biology, 2019, Volume: 1155

    Topics: Animals; Dietary Sugars; Dietary Supplements; Female; Myocardial Ischemia; Pregnancy; Rats; Rats, Sp

2019
Protective effects of taurine against renal ischemia/reperfusion injury in rats by inhibition of gelatinases, MMP-2 and MMP-9, and p38 mitogen-activated protein kinase signaling.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2017, Volume: 92, Issue:7

    Topics: Animals; Blotting, Western; Gelatinases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase

2017
The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model.
    PloS one, 2017, Volume: 12, Issue:11

    Topics: Animals; Apoptosis; Aspartic Acid; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Humans; Hy

2017
UPLC-QTOF/MS-Based Metabolomics Reveals the Protective Mechanism of Hydrogen on Mice with Ischemic Stroke.
    Neurochemical research, 2019, Volume: 44, Issue:8

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Energy Metabolism; Glutathione; Hydrogen; Infa

2019
Taurine attenuates lung ischemia-reperfusion injury after lung transplantation in rats.
    Journal of anesthesia, 2014, Volume: 28, Issue:3

    Topics: Animals; Antioxidants; Disease Models, Animal; Hypertonic Solutions; Lung; Lung Transplantation; Mal

2014
[Morphofunctional state of vessel endothelium at the early stage of cerebral ischemia-reperfusion and the effect of taurin administration].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:12

    Topics: Animals; Blood Coagulation; Brain; Endothelial Cells; Endothelium, Vascular; Male; Platelet Aggregat

2013
Effect of ligustrazine on levels of amino acid neurotransmitters in rat striatum after cerebral ischemia-reperfusion injury.
    Journal of Asian natural products research, 2014, Volume: 16, Issue:11

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid

2014
Effects of ozone therapy and taurine on ischemia/reperfusion-induced testicular injury in a rat testicular torsion model.
    Turkish journal of medical sciences, 2014, Volume: 44, Issue:5

    Topics: Animals; Antioxidants; Disease Models, Animal; In Situ Nick-End Labeling; Male; Oxidants, Photochemi

2014
Effect of taurine on intestinal recovery following intestinal ischemia-reperfusion injury in a rat.
    Pediatric surgery international, 2016, Volume: 32, Issue:2

    Topics: Animals; Blotting, Western; Disease Models, Animal; Intestines; Male; Rats; Rats, Sprague-Dawley; Re

2016
Taurine attenuates multiple organ injury induced by intestinal ischemia reperfusion in rats.
    The Journal of surgical research, 2008, Volume: 149, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Disease Models, Animal; Injections, Intr

2008
Protective effects of taurine against endotoxin-induced acute liver injury after hepatic ischemia reperfusion.
    Amino acids, 2010, Volume: 38, Issue:1

    Topics: Animals; Caspase 3; Endotoxins; Injections, Intravenous; L-Lactate Dehydrogenase; Liver; Male; Malon

2010
Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury.
    Microcirculation (New York, N.Y. : 1994), 2009, Volume: 16, Issue:7

    Topics: Alanine; Animals; Arginine; Chemotaxis, Leukocyte; Clinical Enzyme Tests; Drug Therapy, Combination;

2009
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage.
    European journal of pharmacology, 2009, Oct-25, Volume: 621, Issue:1-3

    Topics: Animals; Biomimetics; Brain; Chloride Channels; Edema; Glucose; Glutamic Acid; In Vitro Techniques;

2009
Taurine protects against lung damage following limb ischemia reperfusion in the rat by attenuating endoplasmic reticulum stress-induced apoptosis.
    Acta orthopaedica, 2010, Volume: 81, Issue:2

    Topics: Animals; Apoptosis; Disease Models, Animal; Endoplasmic Reticulum; Ischemia; Lung; Male; Oxidative S

2010
High sugar intake exacerbates cardiac reperfusion injury in perinatal taurine depleted adult rats.
    Journal of biomedical science, 2010, Aug-24, Volume: 17 Suppl 1

    Topics: Animals; Baroreflex; Blood Pressure; Body Weight; Dietary Carbohydrates; Female; Heart Rate; Humans;

2010
Differential effects of taurine treatment and taurine deficiency on the outcome of renal ischemia reperfusion injury.
    Journal of biomedical science, 2010, Aug-24, Volume: 17 Suppl 1

    Topics: Animals; Apoptosis; Aquaporin 2; Cell Proliferation; Kidney; Kidney Diseases; Kidney Function Tests;

2010
[Relationship between lung injury induced by hemorrhagic shock/reperfusion and nitric oxide and beneficial effect of taurine].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2004, Volume: 20, Issue:1

    Topics: Animals; Lung; Lung Injury; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Reperfusion Injury; Shock,

2004
Glycine and taurine equally prevent fatty livers from Kupffer cell-dependent injury: an in vivo microscopy study.
    Microcirculation (New York, N.Y. : 1994), 2011, Volume: 18, Issue:3

    Topics: Animals; Cell Communication; Clinical Enzyme Tests; Fatty Liver; Female; Glycine; Kupffer Cells; Mic

2011
[Effects of taurine on the changes of PLA2 during acute lung injury following limbs ischemia/reperfusion of rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2007, Volume: 23, Issue:4

    Topics: Acute Lung Injury; Animals; Extremities; Group II Phospholipases A2; Male; Rats; Rats, Wistar; Reper

2007
[Effects of taurine on TNF-alpha and NF-kappaB expression of liver injury after limbs ischemia/reperfusion in rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2009, Volume: 25, Issue:1

    Topics: Animals; Extremities; Ischemia; Liver; Male; NF-kappa B; Protective Agents; Random Allocation; Rats;

2009
[Effects of taurine on rabbit cardiomyocyte apoptosis during ischemia/reperfusion injury].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2004, Volume: 20, Issue:3

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Male; Myocardial Ischemia; Myocytes, Cardiac; Rab

2004
[The protective effect of taurine on lung injury following limbs ischemia/reperfusion of rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2004, Volume: 20, Issue:3

    Topics: Animals; Hindlimb; Lung; Lung Injury; Male; Malondialdehyde; Rats; Rats, Wistar; Reactive Oxygen Spe

2004
Effects of taurine on reperfusion injury.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2011, Volume: 64, Issue:7

    Topics: Animals; Antioxidants; Biopsy, Needle; Disease Models, Animal; Follow-Up Studies; Graft Rejection; G

2011
Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.
    Amino acids, 2012, Volume: 42, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Brain; Cell Death; Disease Models, Animal; Gene Expression Regula

2012
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage.
    Amino acids, 2012, Volume: 42, Issue:6

    Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Brain Ischemia; gamma-Aminobutyric Acid; Glucose; Male

2012
Transgenic expression of nonclassically secreted FGF suppresses kidney repair.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Animals; Base Sequence; Cell Enlargement; DNA Primers; Endothelial Cells; Fibroblast Growth Factor 1

2012
Beneficial effects of taurine and carnosine in experimental ischemia/reperfusion injury in testis.
    Pediatric surgery international, 2012, Volume: 28, Issue:11

    Topics: Animals; Carnosine; Male; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion; Taurine; T

2012
Ischemia/reperfusion injury of skeletal muscle: plasma taurine as a measure of tissue damage.
    Surgery, 2003, Volume: 133, Issue:1

    Topics: Animals; Biomarkers; Cell Membrane; Creatine Kinase; L-Lactate Dehydrogenase; Male; Malondialdehyde;

2003
Taurine reduces renal ischemia/reperfusion injury in the rat.
    Advances in experimental medicine and biology, 2003, Volume: 526

    Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Ischemia; Isoenzymes; Kidney; L-Lactate Dehydrogenase;

2003
Ischemia and reoxygenation induced amino acid release release and tissue damage in the slices of rat corpus striatum.
    Amino acids, 2004, Volume: 27, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Citrulline; Corpus Striatum; Female; gamma-Amin

2004
Validity of elevated interstitial levels of taurine as a predictor of myocardial ischemic injury.
    Amino acids, 2004, Volume: 27, Issue:1

    Topics: Animals; Area Under Curve; Ischemia; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfus

2004
[Effects of tianma gouteng fang on transmitter amino acids in the hippocampus extracellular liquids in freely moving rats subjected to brain ischemia].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:11

    Topics: Animals; Arginine; Brain Ischemia; Drug Combinations; Drugs, Chinese Herbal; Excitatory Amino Acids;

2004
Effects of systemic and regional taurine on skeletal muscle function following ischaemia-reperfusion injury.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2005, Volume: 23, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Hindlimb; Male; Muscle Contraction; Muscle, Skeletal; Rat

2005
Taurine inhibits ischemia/reperfusion-induced compartment syndrome in rabbits.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:7

    Topics: Animals; Compartment Syndromes; L-Lactate Dehydrogenase; Malondialdehyde; Muscle, Skeletal; Oxidativ

2005
Taurine protects against ischemia-reperfusion injury in rabbit livers.
    Transplantation proceedings, 2006, Volume: 38, Issue:5

    Topics: Animals; Disease Models, Animal; Injections, Intravenous; Kinetics; Lipid Peroxidation; Liver; Liver

2006
The effect of taurine on renal ischemia/reperfusion injury.
    Amino acids, 2007, Volume: 32, Issue:3

    Topics: Animals; Antioxidants; Biomarkers; Kidney; Kidney Diseases; Male; Random Allocation; Rats; Rats, Wis

2007
Taurine protects from liver injury after warm ischemia in rats: the role of kupffer cells.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2007, Volume: 39, Issue:5

    Topics: Animals; Cell Communication; Endothelial Cells; Female; Intercellular Adhesion Molecule-1; Kupffer C

2007
Donor preconditioning with taurine protects kidney grafts from injury after experimental transplantation.
    The Journal of surgical research, 2008, May-01, Volume: 146, Issue:1

    Topics: Animals; Apoptosis; Biopsy; Caspase 3; Dose-Response Relationship, Drug; Female; Graft Rejection; HS

2008
Beneficial effect of taurine on testicular ischemia-reperfusion injury in rats.
    Urology, 2007, Volume: 70, Issue:6

    Topics: Animals; Antioxidants; Biopsy; Germ Cells; Male; Malondialdehyde; Organ Size; Peroxidase; Rats; Rats

2007
Novel molecular mechanism to account for action of taurine against testicular ischemia-reperfusion injury.
    Urology, 2008, Volume: 72, Issue:2

    Topics: Down-Regulation; Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Lymphocyte Function-A

2008
Taurine reduces testicular ischemia/reperfusion-induced neutrophil recruitment to testis probably by downregulation of pro-inflammatory cytokines and E-selectin.
    Urology, 2008, Volume: 72, Issue:2

    Topics: Cytokines; Down-Regulation; E-Selectin; Humans; Interleukin-1beta; Male; Neutrophil Infiltration; Re

2008
[Protective action of taurine on ischemia-reperfusion liver injury in rats and its mechanism].
    Zhonghua yi xue za zhi, 1993, Volume: 73, Issue:5

    Topics: Animals; Calcium; Ischemia; L-Lactate Dehydrogenase; Lipid Peroxides; Liver; Male; Malondialdehyde;

1993
Secondary elevation of extracellular neurotransmitter amino acids in the reperfusion phase following focal cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1996, Volume: 16, Issue:1

    Topics: Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cerebrosp

1996
Taurine reduces experimental liver injury after cold ischemic preservation and a period of rewarming prior to reperfusion.
    Advances in experimental medicine and biology, 1996, Volume: 403

    Topics: Adenosine; Alanine Transaminase; Allopurinol; Animals; Biomarkers; Cold Temperature; Glutamate Dehyd

1996
Protective effect of taurine against reperfusion injury in cultured rat astrocytes.
    Advances in experimental medicine and biology, 1996, Volume: 403

    Topics: Animals; Animals, Newborn; Astrocytes; beta-Alanine; Calcium; Cell Survival; Cells, Cultured; Cerebr

1996
Taurine in gerbil retina: changes during ischemia reperfusion/insult (I.R.I.) and aging.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1996,Spring, Volume: 12, Issue:1

    Topics: Aging; Animals; Chromatography, High Pressure Liquid; Electrochemistry; Female; Gerbillinae; Ischemi

1996
Differential effects of lower limb revascularisation on organ injury and the role of the amino acid taurine.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 1997, Volume: 13, Issue:2

    Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Hindlimb; Kidney; Liver; Lung; Male;

1997
Cytoprotection by the osmolytes betaine and taurine in ischemia-reoxygenation injury in the perfused rat liver.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Betaine; Cytoprotecti

1997
Effect of alpha-tocopherol, taurine and selenium on the attenuation of ischemia/reperfusion injury of splanchnic organs.
    Cardiovascular surgery (London, England), 1998, Volume: 6, Issue:2

    Topics: Animals; Cecum; Disease Models, Animal; Duodenum; Ileum; Jejunum; Male; Random Allocation; Rats; Rat

1998
Warm blood cardioplegia reduces the fall in the intracellular concentration of taurine in the ischaemic/reperfused heart of patients undergoing aortic valve surgery.
    Amino acids, 1998, Volume: 15, Issue:4

    Topics: Adenosine Triphosphate; Aged; Aortic Valve; Aortic Valve Stenosis; Female; Heart Arrest, Induced; Hu

1998
Taurine and calcium interaction in protection of myocardium exposed to ischemic reperfusion injury.
    General pharmacology, 1999, Volume: 33, Issue:2

    Topics: Animals; Calcium; Drug Combinations; Drug Interactions; Guinea Pigs; Heart Rate; Male; Malondialdehy

1999
Lactate reduces amino acid release and fuels recovery of function in the ischemic brain.
    Neuroscience letters, 1999, Sep-17, Volume: 272, Issue:3

    Topics: Amino Acids; Animals; Brain Ischemia; Cerebral Cortex; Electroencephalography; Injections; Lactic Ac

1999
Topical glucose and accumulation of excitotoxic and other amino acids in ischemic cerebral cortex.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2000, Volume: 32, Issue:1

    Topics: Animals; Aspartic Acid; Blood Pressure; Brain Ischemia; Carbon Dioxide; Cerebral Cortex; Ethanolamin

2000
Transporter reversal as a mechanism of glutamate release from the ischemic rat cerebral cortex: studies with DL-threo-beta-benzyloxyaspartate.
    Brain research, 2000, Jun-16, Volume: 868, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain I

2000
Taurine attenuates cold ischemia-reoxygenation injury in rat liver.
    Transplantation, 2000, Jun-15, Volume: 69, Issue:11

    Topics: Animals; Betaine; Cryopreservation; Inositol; Ischemia; Liver; Liver Circulation; Male; Rats; Rats,

2000
The effect of intravenous insulin on accumulation of excitotoxic and other amino acids in the ischemic rat cerebral cortex.
    Neuroscience letters, 2000, Jul-07, Volume: 288, Issue:1

    Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Energy Metabolism; gamma-Aminobutyric Acid

2000
Taurine protects against early and late skeletal muscle dysfunction secondary to ischaemia reperfusion injury.
    The European journal of surgery = Acta chirurgica, 2000, Volume: 166, Issue:5

    Topics: Animals; Electrophysiology; Muscle Contraction; Muscle, Skeletal; Random Allocation; Rats; Rats, Spr

2000
pH-stat strategies protect 60-minute central nervous system ischemia at 29.5 degrees C.
    The Annals of thoracic surgery, 2000, Volume: 70, Issue:3

    Topics: Animals; Central Nervous System; Humans; Hydrogen-Ion Concentration; Hypothermia, Induced; Rabbits;

2000
Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation.
    Acta physiologica Scandinavica, 2001, Volume: 171, Issue:2

    Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Dialysis Solutions; Disease Models, Animal

2001
Protection of intrinsic nerves of guinea-pig detrusor strips against anoxia/glucopenia and reperfusion injury by taurine.
    Advances in experimental medicine and biology, 2000, Volume: 483

    Topics: Aminoethylphosphonic Acid; Animals; Atropine; Electric Stimulation; Evoked Potentials; Glucose; Guin

2000
Effect of ellagic acid on gastric damage induced in ischemic rat stomachs following ammonia or reperfusion.
    Life sciences, 2002, Jan-25, Volume: 70, Issue:10

    Topics: Ammonia; Animals; Antioxidants; Dose-Response Relationship, Drug; Ellagic Acid; Gastric Mucosa; Isch

2002
The role of taurine added to pulmonary reperfusion solutions in isolated guinea pig lungs.
    Amino acids, 2002, Volume: 22, Issue:4

    Topics: Animals; Glutathione; Guinea Pigs; Ischemia; Lung; Male; Malondialdehyde; Protective Agents; Reperfu

2002
Effects of taurine and ketamine on bovine retinal membrane lipid peroxidation.
    Neuroscience, 1991, Volume: 45, Issue:2

    Topics: Animals; Ascorbic Acid; Cadmium; Cadmium Chloride; Calcium; Cattle; Dextromethorphan; Female; Ischem

1991