taurine has been researched along with Pulmonary Fibrosis in 22 studies
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " PA and Tau effectively inhibited inflammation, edema, severity of fibrosis, fibrosis extension, inflammatory cell accumulation, iNOS staining, and hydroxyproline level as well (p < 0." | 7.78 | The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine. ( Agackiran, Y; Akyurek, N; Gul, H; Gunay, E; Gunay, S; Ide, T; Memis, L; Sirin, YS, 2012) |
| "Taurine and niacin have been previously found to block the accumulation of collagen in lung in the multidose bleomycin hamster model of pulmonary fibrosis." | 7.69 | Dietary supplementation with taurine and niacin prevents the increase in lung collagen cross-links in the multidose bleomycin hamster model of pulmonary fibrosis. ( Blaisdell, RJ; Giri, SN; Schiedt, MJ, 1994) |
| "Taurine has the ability to resist the action of oxygen-free radicals by protecting cytomembranes." | 5.30 | The protective action of taurine and L-arginine in radiation pulmonary fibrosis. ( Cui, X; Hu, W; Song, L; Wang, D, 1998) |
| "Interstitial pulmonary fibrosis induced by bleomycin (BL) involves the production of reactive oxygen species and the impairment of repair of damaged epithelial cells." | 5.28 | Amelioration of bleomycin-induced pulmonary fibrosis in hamsters by combined treatment with taurine and niacin. ( Giri, SN; Hyde, DM; Li, C; Wang, QJ, 1991) |
| " PA and Tau effectively inhibited inflammation, edema, severity of fibrosis, fibrosis extension, inflammatory cell accumulation, iNOS staining, and hydroxyproline level as well (p < 0." | 3.78 | The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine. ( Agackiran, Y; Akyurek, N; Gul, H; Gunay, E; Gunay, S; Ide, T; Memis, L; Sirin, YS, 2012) |
| "Taurine and niacin have been previously found to block the accumulation of collagen in lung in the multidose bleomycin hamster model of pulmonary fibrosis." | 3.69 | Dietary supplementation with taurine and niacin prevents the increase in lung collagen cross-links in the multidose bleomycin hamster model of pulmonary fibrosis. ( Blaisdell, RJ; Giri, SN; Schiedt, MJ, 1994) |
| "In the multiple-dose bleomycin-hamster model of pulmonary fibrosis, combined treatment with taurine and niacin blocks the increase in lung collagen deposition." | 3.69 | Mechanism of antifibrotic effect of taurine and niacin in the multidose bleomycin-hamster model of lung fibrosis: inhibition of lysyl oxidase and collagenase. ( Blaisdell, RJ; Giri, SN, 1995) |
| "Taurine (T) and niacin (N) have previously been found to block the accumulation of collagen in the bleomycin (BL) model of interstitial pulmonary fibrosis." | 3.69 | Procollagen gene expression is down-regulated by taurine and niacin at the transcriptional level in the bleomycin hamster model of lung fibrosis. ( Giri, SN; Gurujeyalakshmi, G; Hollinger, MA; Iyer, SN, 1996) |
| "Combined treatment with taurine and niacin suppressed BL-induced inflammation and almost completely abrogated pulmonary fibrosis in hamsters." | 3.68 | Abatement of bleomycin-induced increases in vascular permeability, inflammatory cell infiltration, and fibrotic lesions in hamster lungs by combined treatment with taurine and niacin. ( Giri, SN; Hyde, DM; Wang, Q, 1992) |
| "Hydroxyproline content was also significantly lower at 14 weeks in mice treated with taurine (P = 0." | 1.36 | Taurine attenuates radiation-induced lung fibrosis in C57/Bl6 fibrosis prone mice. ( Bouchier-Hayes, DJ; Condron, C; Moriarty, M; Robb, WB; Walsh, TN, 2010) |
| "Treatment with taurine and niacin attenuated the BL-induced increases in proinflammatory cytokines such as IL-1alpha, TNF-alpha, IL-6, and TGF-beta in BALF and lung hydroxyproline content of the mice in BL + TN groups." | 1.31 | Taurine and niacin block lung injury and fibrosis by down-regulating bleomycin-induced activation of transcription nuclear factor-kappaB in mice. ( Giri, SN; Gurujeyalakshmi, G; Wang, Y, 2000) |
| "Taurine and niacin treatment significantly reduced the numbers of neutrophils, lymphocytes, and macrophages in the BL + TN group and caused significant reductions in BL-induced increases in the lung hydroxyproline content at 14 and 21 days in the BL + TN group." | 1.31 | Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin. ( Giri, SN; Gurujeyalakshmi, G; Wang, Y, 2000) |
| "Taurine has the ability to resist the action of oxygen-free radicals by protecting cytomembranes." | 1.30 | The protective action of taurine and L-arginine in radiation pulmonary fibrosis. ( Cui, X; Hu, W; Song, L; Wang, D, 1998) |
| "Interstitial pulmonary fibrosis induced by intratracheal instillation of bleomycin (BL) involves an excess production of reactive oxygen species, unavailability of adequate levels of NAD and ATP to repair the injured pulmonary epithelium, and an overexuberant lung collagen reactivity followed by deposition of highly cross-linked mature collagen fibrils resistant to enzymatic degradation." | 1.29 | Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms. ( Blaisdell, R; Giri, SN; Hyde, DM; Rucker, RB; Wang, Q, 1994) |
| "Interstitial pulmonary fibrosis induced by bleomycin (BL) involves the production of reactive oxygen species and the impairment of repair of damaged epithelial cells." | 1.28 | Amelioration of bleomycin-induced pulmonary fibrosis in hamsters by combined treatment with taurine and niacin. ( Giri, SN; Hyde, DM; Li, C; Wang, QJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 11 (50.00) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, H | 1 |
| Meng, HY | 1 |
| Bai, WF | 1 |
| Meng, QG | 1 |
| Robb, WB | 1 |
| Condron, C | 1 |
| Moriarty, M | 1 |
| Walsh, TN | 1 |
| Bouchier-Hayes, DJ | 1 |
| Agackiran, Y | 1 |
| Gul, H | 1 |
| Gunay, E | 1 |
| Akyurek, N | 1 |
| Memis, L | 1 |
| Gunay, S | 1 |
| Sirin, YS | 1 |
| Ide, T | 1 |
| Giri, SN | 13 |
| Schuller-Levis, GB | 1 |
| Gordon, RE | 1 |
| Wang, C | 1 |
| Park, E | 1 |
| Du, HK | 1 |
| Wang, SX | 1 |
| Blaisdell, RJ | 2 |
| Schiedt, MJ | 1 |
| Blaisdell, R | 1 |
| Rucker, RB | 1 |
| Wang, Q | 4 |
| Hyde, DM | 4 |
| Gurujeyalakshmi, G | 4 |
| Iyer, SN | 1 |
| Hollinger, MA | 3 |
| Song, L | 1 |
| Wang, D | 1 |
| Cui, X | 1 |
| Hu, W | 1 |
| Wang, Y | 2 |
| Cortijo, J | 1 |
| Cerdá-Nicolás, M | 1 |
| Serrano, A | 1 |
| Bioque, G | 1 |
| Estrela, JM | 1 |
| Santangelo, F | 1 |
| Esteras, A | 1 |
| Llombart-Bosch, A | 1 |
| Morcillo, EJ | 1 |
| Lasky, JA | 1 |
| Ortiz, LA | 1 |
| Mangum, JB | 1 |
| Everitt, JI | 1 |
| Bonner, JC | 1 |
| Moore, LR | 1 |
| Brody, AR | 1 |
| Wang, QJ | 2 |
| Li, C | 1 |
| Nakashima, JM | 1 |
2 reviews available for taurine and Pulmonary Fibrosis
| Article | Year |
|---|---|
[Mechanism and effect of taurine on pulmonary fibrosis].
Topics: Calcium; Growth Substances; Humans; Pulmonary Fibrosis; Taurine | 2003 |
Antifibrotic therapy for the treatment of pulmonary fibrosis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Clinical Trials as Topi | 2001 |
20 other studies available for taurine and Pulmonary Fibrosis
| Article | Year |
|---|---|
A metabolomic approach to elucidate the inhibitory effects of baicalin in pulmonary fibrosis.
Topics: Animals; Biomarkers; Flavonoids; Glutathione; Glycerophospholipids; Lung; Male; Metabolomics; Models | 2021 |
Taurine attenuates radiation-induced lung fibrosis in C57/Bl6 fibrosis prone mice.
Topics: Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Hydroxy | 2010 |
The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine.
Topics: Animals; Antioxidants; Bleomycin; Grape Seed Extract; Hydroxyproline; Inflammation; Lung; Lymphocyte | 2012 |
The combined treatment with taurine and niacin blocks the bleomycin-induced activation of nuclear factor-kappaB and lung fibrosis.
Topics: Animals; Base Sequence; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Cytokines; Disea | 2003 |
Taurine reduces lung inflammation and fibrosis caused by bleomycin.
Topics: Animals; Immunohistochemistry; Lung; Microscopy, Electron; Pneumonia; Pulmonary Fibrosis; Rats; Rats | 2003 |
Dietary supplementation with taurine and niacin prevents the increase in lung collagen cross-links in the multidose bleomycin hamster model of pulmonary fibrosis.
Topics: Animals; Bleomycin; Collagen; Cricetinae; Diet; Dipeptides; Disease Models, Animal; Male; Mesocricet | 1994 |
Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cricetinae; Diet; Hydroxyproline; Lung; | 1994 |
Mechanism of antifibrotic effect of taurine and niacin in the multidose bleomycin-hamster model of lung fibrosis: inhibition of lysyl oxidase and collagenase.
Topics: Animals; Bleomycin; Cricetinae; Hydroxyproline; Male; Matrix Metalloproteinase Inhibitors; Mesocrice | 1995 |
Procollagen gene expression is down-regulated by taurine and niacin at the transcriptional level in the bleomycin hamster model of lung fibrosis.
Topics: Animals; Bleomycin; Collagen; Cricetinae; Gene Expression Regulation; Male; Mesocricetus; Niacin; Pr | 1996 |
Regulation of transforming growth factor-beta1 mRNA expression by taurine and niacin in the bleomycin hamster model of lung fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cricetinae; Diet; Disease Models, Animal | 1998 |
The protective action of taurine and L-arginine in radiation pulmonary fibrosis.
Topics: Animals; Arginine; Azo Compounds; Collagen; Hydroxyproline; Image Processing, Computer-Assisted; In | 1998 |
Taurine and niacin block lung injury and fibrosis by down-regulating bleomycin-induced activation of transcription nuclear factor-kappaB in mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Down-Reg | 2000 |
Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation | 2000 |
Attenuation by oral N-acetylcysteine of bleomycin-induced lung injury in rats.
Topics: Acetylcysteine; Administration, Oral; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Free Radical | 2001 |
Abatement of bleomycin-induced increases in vascular permeability, inflammatory cell infiltration, and fibrotic lesions in hamster lungs by combined treatment with taurine and niacin.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Membrane Permeability; Cricetinae; Drug Thera | 1992 |
Taurine and niacin offer a novel therapeutic modality in prevention of chemically-induced pulmonary fibrosis in hamsters.
Topics: Amiodarone; Animals; Bleomycin; Cricetinae; Drug Therapy, Combination; Niacin; Pulmonary Fibrosis; T | 1992 |
Attenuation of amiodarone-induced lung fibrosis and phospholipidosis in hamsters by taurine and/or niacin treatment.
Topics: Administration, Oral; Amiodarone; Animals; Collagen; Cricetinae; Drug Combinations; Hydroxyproline; | 1992 |
Co-culture of primary pulmonary cells to model alveolar injury and translocation of proteins.
Topics: alpha-Macroglobulins; Animals; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Co | 1990 |
Amelioration of bleomycin-induced pulmonary fibrosis in hamsters by combined treatment with taurine and niacin.
Topics: Administration, Oral; Animals; Bleomycin; Calcium; Cricetinae; Drug Therapy, Combination; Hydroxypro | 1991 |
Effects of taurine on bleomycin-induced lung fibrosis in hamsters.
Topics: Animals; Bleomycin; Body Weight; Bronchoalveolar Lavage Fluid; Collagen; Cricetinae; Lung; Male; Mes | 1989 |