Page last updated: 2024-10-20

taurine and Parkinson Disease

taurine has been researched along with Parkinson Disease in 16 studies

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"Homotaurine is a natural compound of red algae, which has been demonstrated to have a neuroprotective effect and has been evaluated as a possible therapeutic agent for Alzheimer's disease."2.80Homotaurine in Parkinson's disease. ( De Nigris, F; Fasano, A; Ricciardi, L; Specchia, A, 2015)
" Interestingly, plasma taurine levels negatively correlated with cumulative levodopa dosage in tPD."1.43Reduced plasma taurine level in Parkinson's disease: association with motor severity and levodopa treatment. ( Ding, J; Jiang, S; Tong, Q; Xu, Q; Yuan, Y; Zhang, K; Zhang, L; Zhang, R, 2016)
"Lethargy and mental depression are early symptoms, followed by mild parkinsonism and progressive weight loss."1.26Familial fatal Parkinsonism with alveolar hypoventilation and mental depression. ( Ahmad, D; Barnett, HJ; Bratty, P; Hahn, A; Lloyd, KG; McGeer, EG; Perry, TL; Purdy, A, 1979)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's1 (6.25)18.2507
2000's2 (12.50)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Wang, K1
Zhang, B2
Tian, T1
Shi, G1
Zhang, C1
Li, G1
Huang, M1
Ren, X1
Hinchie, A1
Swomley, A1
Powell, DK1
Butterfield, DA1
Abuirmeileh, AN1
Abuhamdah, SM1
Ashraf, A1
Alzoubi, KH1
Stiles, L1
Zheng, Y1
Smith, PF1
Ricciardi, L1
De Nigris, F1
Specchia, A1
Fasano, A1
Zhang, L2
Yuan, Y1
Tong, Q1
Jiang, S1
Xu, Q1
Ding, J1
Zhang, R1
Zhang, K1
Hajj, R1
Milet, A1
Toulorge, D1
Cholet, N1
Laffaire, J1
Foucquier, J1
Robelet, S1
Mitry, R1
Guedj, M1
Nabirotchkin, S1
Chumakov, I1
Cohen, D1
Mehta, NJ1
Asmaro, K1
Hermiz, DJ1
Njus, MM1
Saleh, AH1
Beningo, KA1
Njus, D1
Morales, I1
Dopico, JG1
Sabate, M1
Gonzalez-Hernandez, T1
Rodriguez, M1
Plaitakis, A1
Berl, S1
Tanaka, Y1
Mizuno, Y1
Hayes, J1
Tipton, KF1
Bianchi, L1
Corte, LD1
Purdy, A1
Hahn, A1
Barnett, HJ1
Bratty, P1
Ahmad, D1
Lloyd, KG1
McGeer, EG1
Perry, TL4
Bratty, PJ1
Hansen, S3
Kennedy, J1
Urquhart, N1
Dolman, CL1
Bergeron, C1
Steele, JC1
McLachlan, DR1
Kloster, M1

Trials

1 trial available for taurine and Parkinson Disease

ArticleYear
Homotaurine in Parkinson's disease.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36, Issue:9

    Topics: Aged; Antiparkinson Agents; Cognition Disorders; Disorders of Excessive Somnolence; Female; Humans;

2015

Other Studies

15 other studies available for taurine and Parkinson Disease

ArticleYear
Taurine protects dopaminergic neurons in paraquat-induced Parkinson's disease mouse model through PI3K/Akt signaling pathways.
    Amino acids, 2022, Volume: 54, Issue:1

    Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Paraquat; Parkinson

2022
Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease.
    Free radical biology & medicine, 2019, 11-01, Volume: 143

    Topics: Animals; Aspartic Acid; Biomarkers; Brain; Corpus Striatum; Disease Models, Animal; Female; Gene Kno

2019
Protective effect of caffeine and/or taurine on the 6-hydroxydopamine-induced rat model of Parkinson's disease: Behavioral and neurochemical evidence.
    Restorative neurology and neuroscience, 2021, Volume: 39, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Caffeine; Corpus Striatum; Disease Models, Animal; Dopamine;

2021
The effects of electrical stimulation of the peripheral vestibular system on neurochemical release in the rat striatum.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Electric S

2018
Reduced plasma taurine level in Parkinson's disease: association with motor severity and levodopa treatment.
    The International journal of neuroscience, 2016, Volume: 126, Issue:7

    Topics: Aged; Antiparkinson Agents; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Severity

2016
Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson's disease.
    Scientific reports, 2015, Nov-06, Volume: 5

    Topics: Acamprosate; Animals; Baclofen; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dopamine;

2015
Hypochlorite converts cysteinyl-dopamine into a cytotoxic product: A possible factor in Parkinson's Disease.
    Free radical biology & medicine, 2016, Volume: 101

    Topics: Animals; Cell Survival; Cytotoxins; Dopamine; Humans; Hypochlorous Acid; Models, Biological; Oxidati

2016
Substantia nigra osmoregulation: taurine and ATP involvement.
    American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:5

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Choline; Dose-Response Relati

2007
Oral glutamate loading in disorders with spinocerebellar and extrapyramidal involvement: effect on plasma glutamate, aspartate and taurine.
    Journal of neural transmission. Supplementum, 1983, Volume: 19

    Topics: Aspartic Acid; Atrophy; Basal Ganglia Diseases; Cerebellar Diseases; Cerebellum; Friedreich Ataxia;

1983
[GABA, glutamate, aspartate, glycine, and taurine contents in spinocerebellar degeneration and parkinsonism].
    Rinsho shinkeigaku = Clinical neurology, 1984, Volume: 24, Issue:3

    Topics: Adult; Aged; Amino Acids; Aspartic Acid; Brain Chemistry; Cerebellar Ataxia; Chromatography, High Pr

1984
Complexities in the neurotoxic actions of 6-hydroxydopamine in relation to the cytoprotective properties of taurine.
    Brain research bulletin, 2001, May-15, Volume: 55, Issue:2

    Topics: Aconitate Hydratase; Adrenergic Agents; Animals; Dopamine; Extracellular Space; gamma-Aminobutyric A

2001
Familial fatal Parkinsonism with alveolar hypoventilation and mental depression.
    Annals of neurology, 1979, Volume: 6, Issue:6

    Topics: Brain; Brain Chemistry; Depression; Dopa Decarboxylase; Dopamine; gamma-Aminobutyric Acid; Glutamate

1979
Hereditary mental depression and Parkinsonism with taurine deficiency.
    Archives of neurology, 1975, Volume: 32, Issue:2

    Topics: Age Factors; Aged; Antidepressive Agents; Body Weight; Brain; Depression; Electroconvulsive Therapy;

1975
Brain amino acid contents are dissimilar in sporadic and Guamanian amyotrophic lateral sclerosis.
    Journal of the neurological sciences, 1990, Volume: 99, Issue:1

    Topics: Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Brain; Female; gamma-Aminobutyric Acid; Glutamates

1990
Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain.
    The New England journal of medicine, 1973, Feb-15, Volume: 288, Issue:7

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autopsy; Basal Ganglia; Brain; Br

1973