taurine has been researched along with Neoplasm Metastasis in 14 studies
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and tolerability of taurolidine, an antibacterial substance, was evaluated in a phase 2 trial enrolling patients with advanced melanoma." | 9.15 | The antibacterial substance, taurolidine in the second/third-line treatment of very advanced stage IV melanoma including brain metastases: results of a phase 2, open-label study. ( Baumann, K; Dummer, R; French, LE; Goldinger, SM; Imhof, L; Röthlisberger, P; Schad, K, 2011) |
| " This study examined the effect of administration of taurolidine after laparotomy or laparoscopy on the growth of solid tumor, the establishment of hepatic and lung metastases, and effects on natural killer (NK) and lymphokine-activated killer (LAK) cell function." | 7.71 | Taurolidine improves survival by abrogating the accelerated development and proliferation of solid tumors and development of organ metastases from circulating tumor cells released following surgery. ( Bouchier-Hayes, DJ; Da Costa, ML; Redmond, HP, 2001) |
| "The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often correlated with tumor progression and poorer clinical outcomes." | 5.48 | Taurine up-regulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma. ( Chen, CY; Cheng, ML; Chi, HC; Chung, IH; Huang, YH; Lin, KH; Lin, YH; Tsai, CY; Wu, MH; Yeh, CT, 2018) |
| "The efficacy and tolerability of taurolidine, an antibacterial substance, was evaluated in a phase 2 trial enrolling patients with advanced melanoma." | 5.15 | The antibacterial substance, taurolidine in the second/third-line treatment of very advanced stage IV melanoma including brain metastases: results of a phase 2, open-label study. ( Baumann, K; Dummer, R; French, LE; Goldinger, SM; Imhof, L; Röthlisberger, P; Schad, K, 2011) |
| " MRS (two patients with medulloblastoma and one with a SPNET), showed elevated choline, decreased N-acetyl aspartate, and a small taurine peak in all three patients." | 3.74 | Paediatric PNET: pre-surgical MRI features. ( Chawla, A; Emmanuel, JV; Lim, CC; Lou, J; Seow, WT; Teo, HE, 2007) |
| "VEGF and TNFalpha levels of rat colon adenocarcinoma cells (DHD/K12/TRb) were analyzed in the supernatant undergoing treatment of increasing taurolidine doses in vitro." | 3.73 | Effects of increasing doses of a bolus injection and an intravenous long-term therapy of taurolidine on subcutaneous (metastatic) tumor growth in rats. ( Braumann, C; Jacobi, CA; Kilian, M; Menenakos, C; Schoenbeck, M, 2005) |
| " This study examined the effect of administration of taurolidine after laparotomy or laparoscopy on the growth of solid tumor, the establishment of hepatic and lung metastases, and effects on natural killer (NK) and lymphokine-activated killer (LAK) cell function." | 3.71 | Taurolidine improves survival by abrogating the accelerated development and proliferation of solid tumors and development of organ metastases from circulating tumor cells released following surgery. ( Bouchier-Hayes, DJ; Da Costa, ML; Redmond, HP, 2001) |
| "The effects of taurolidine, heparin, and povidone iodine on the growth of rat and human colon adenocarcinoma as well as gallbladder carcinoma were investigated in vitro." | 3.70 | New therapeutic strategies to avoid intra- and extraperitoneal metastases during laparoscopy: results of a tumor model in the rat. ( Jacobi, CA; Müller, JM; Ordemann, J; Peter, FJ; Wenger, FA, 1999) |
| "After subcutaneous and intraperitoneal injection of 10(4) cells of colon adenocarcinoma (DHD/K12/TRb) the influences of either taurolidine or taurolidine/heparin on intraperitoneal and subcutaneous tumour growth were investigated in 105 rats undergoing laparoscopy with carbon dioxide." | 3.70 | Influence of intraperitoneal and systemic application of taurolidine and taurolidine/heparin during laparoscopy on intraperitoneal and subcutaneous tumour growth in rats. ( Braumann, C; Jacobi, CA; Ordemann, J; Wildbrett, P, 2000) |
| "The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often correlated with tumor progression and poorer clinical outcomes." | 1.48 | Taurine up-regulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma. ( Chen, CY; Cheng, ML; Chi, HC; Chung, IH; Huang, YH; Lin, KH; Lin, YH; Tsai, CY; Wu, MH; Yeh, CT, 2018) |
| "Human pancreatic cancer cell lines representing diverse states of differentiation were exposed to TRD for 24 h." | 1.40 | Taurolidine induces epithelial-mesenchymal transition via up-regulation of the transcription factor Snail in human pancreatic cancer cell lines. ( Arndt, M; Buhr, HJ; Erben, U; Hotz, B; Hotz, HG, 2014) |
| "330 mg) of intraperitoneal metastases in comparison to the control group (p = 0." | 1.34 | Instillation of taurolidine/heparin after laparotomy reduces intraperitoneal tumour growth in a colon cancer rat model. ( Braumann, C; Jacobi, CA; Mueller, JM; Opitz, I; Van der Veen, H; Witte, N, 2007) |
| "Furthermore the number of liver metastasis per animal was reduced after lavage with taurolidin (2 +/- 2) and Octreotide (2." | 1.33 | Impact of taurolidin and octreotide on liver metastasis and lipid peroxidation after laparoscopy in chemical induced ductal pancreatic cancer. ( Braumann, C; Gregor, JI; Guski, H; Heukamp, I; Jacobi, CA; Kilian, M; Schimke, I; Walz, MK; Wenger, FA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, YH | 1 |
| Wu, MH | 1 |
| Huang, YH | 1 |
| Yeh, CT | 1 |
| Cheng, ML | 1 |
| Chi, HC | 1 |
| Tsai, CY | 1 |
| Chung, IH | 1 |
| Chen, CY | 1 |
| Lin, KH | 1 |
| Hotz, B | 1 |
| Erben, U | 1 |
| Arndt, M | 1 |
| Buhr, HJ | 1 |
| Hotz, HG | 1 |
| Imhof, L | 1 |
| Goldinger, SM | 1 |
| Baumann, K | 1 |
| Schad, K | 1 |
| French, LE | 1 |
| Röthlisberger, P | 1 |
| Dummer, R | 1 |
| Shrayer, DP | 1 |
| Lukoff, H | 1 |
| King, T | 1 |
| Calabresi, P | 1 |
| Braumann, C | 5 |
| Ordemann, J | 3 |
| Kilian, M | 3 |
| Wenger, FA | 3 |
| Jacobi, CA | 6 |
| Gregor, JI | 1 |
| Heukamp, I | 1 |
| Guski, H | 1 |
| Schimke, I | 1 |
| Walz, MK | 1 |
| Schoenbeck, M | 1 |
| Menenakos, C | 1 |
| Chawla, A | 1 |
| Emmanuel, JV | 1 |
| Seow, WT | 1 |
| Lou, J | 1 |
| Teo, HE | 1 |
| Lim, CC | 1 |
| Opitz, I | 1 |
| Van der Veen, H | 1 |
| Witte, N | 1 |
| Mueller, JM | 1 |
| Peter, FJ | 1 |
| Müller, JM | 1 |
| Wildbrett, P | 1 |
| Da Costa, ML | 1 |
| Redmond, HP | 1 |
| Bouchier-Hayes, DJ | 1 |
| Gatzemeier, U | 1 |
| Drings, P | 1 |
| Edler, L | 1 |
| Fiebig, HH | 1 |
| Hinke, A | 1 |
| Rieche, K | 1 |
| Tessen, HW | 1 |
| Ernst, P | 1 |
| Balslev, I | 1 |
| Mouridsen, HT | 1 |
2 trials available for taurine and Neoplasm Metastasis
| Article | Year |
|---|---|
The antibacterial substance, taurolidine in the second/third-line treatment of very advanced stage IV melanoma including brain metastases: results of a phase 2, open-label study.
Topics: Adult; Aged; Anti-Infective Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Prot | 2011 |
Chemotherapy with tauromustine in advanced non-small cell lung cancer. A trial of the Phase II Study Group of the Association for Medical Oncology of the German Cancer Society.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Follow-Up Studies; Germany, | 1990 |
12 other studies available for taurine and Neoplasm Metastasis
| Article | Year |
|---|---|
Taurine up-regulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma.
Topics: Biopsy, Needle; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Gene Expression Regulation, Neo | 2018 |
Taurolidine induces epithelial-mesenchymal transition via up-regulation of the transcription factor Snail in human pancreatic cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Survival; Dose-Re | 2014 |
The effect of Taurolidine on adherent and floating subpopulations of melanoma cells.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Drug Screening Assays, Antitumor; Humans; Mel | 2003 |
Local and systemic chemotherapy with taurolidine and taurolidine/heparin in colon cancer-bearing rats undergoing laparotomy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Di | 2003 |
Impact of taurolidin and octreotide on liver metastasis and lipid peroxidation after laparoscopy in chemical induced ductal pancreatic cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Cricetinae; Laparoscop | 2005 |
Effects of increasing doses of a bolus injection and an intravenous long-term therapy of taurolidine on subcutaneous (metastatic) tumor growth in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Colonic Neoplasms; In | 2005 |
Paediatric PNET: pre-surgical MRI features.
Topics: Aspartic Acid; Cerebrospinal Fluid; Child; Child, Preschool; Choline; Creatine; Databases, Factual; | 2007 |
Instillation of taurolidine/heparin after laparotomy reduces intraperitoneal tumour growth in a colon cancer rat model.
Topics: Abdominal Neoplasms; Adenocarcinoma; Animals; Anticoagulants; Antineoplastic Agents; Colonic Neoplas | 2007 |
New therapeutic strategies to avoid intra- and extraperitoneal metastases during laparoscopy: results of a tumor model in the rat.
Topics: Adenocarcinoma; Animals; Anti-Infective Agents, Local; Carbon Dioxide; Colonic Neoplasms; Gallbladde | 1999 |
Influence of intraperitoneal and systemic application of taurolidine and taurolidine/heparin during laparoscopy on intraperitoneal and subcutaneous tumour growth in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Drug Synergi | 2000 |
Taurolidine improves survival by abrogating the accelerated development and proliferation of solid tumors and development of organ metastases from circulating tumor cells released following surgery.
Topics: Animals; Antineoplastic Agents; Cell Division; Cytotoxicity, Immunologic; Female; Killer Cells, Lymp | 2001 |
Second-line chemotherapy with tauromustine in metastatic breast cancer in postmenopausal women: a phase II study.
Topics: Adult; Aged; Breast Neoplasms; Drug Evaluation; Female; Humans; Menopause; Middle Aged; Neoplasm Met | 1987 |