taurine has been researched along with Mitochondrial Diseases in 10 studies
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Taurine is a naturally occurring sulfur-containing amino acid that is found abundantly in excitatory tissues, such as the heart, brain, retina and skeletal muscles." | 2.72 | The Role of Taurine in Mitochondria Health: More Than Just an Antioxidant. ( Jong, CJ; Sandal, P; Schaffer, SW, 2021) |
| "Taurine treatment limited mitochondrial superoxide generation, supporting a role for taurine in maintaining complex I activity." | 1.43 | Mitochondrial defects associated with β-alanine toxicity: relevance to hyper-beta-alaninemia. ( Alexeyev, M; Jong, CJ; Mehdi, AB; Schaffer, SW; Shetewy, A; Shimada-Takaura, K; Takahashi, K; Warner, D, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ueda, S | 1 |
| Yagi, M | 1 |
| Tomoda, E | 1 |
| Matsumoto, S | 1 |
| Ueyanagi, Y | 1 |
| Do, Y | 1 |
| Setoyama, D | 1 |
| Matsushima, Y | 1 |
| Nagao, A | 1 |
| Suzuki, T | 9 |
| Ide, T | 1 |
| Mori, Y | 1 |
| Oyama, N | 1 |
| Kang, D | 1 |
| Uchiumi, T | 1 |
| Kazuhito, T | 1 |
| Wei, FY | 3 |
| Jong, CJ | 2 |
| Sandal, P | 1 |
| Schaffer, SW | 2 |
| Fakruddin, M | 1 |
| Asano, K | 2 |
| Kaieda, T | 1 |
| Omori, A | 1 |
| Izumi, R | 1 |
| Fujimura, A | 1 |
| Kaitsuka, T | 1 |
| Miyata, K | 1 |
| Araki, K | 1 |
| Oike, Y | 1 |
| Scorrano, L | 1 |
| Tomizawa, K | 2 |
| Saito, A | 1 |
| Ikeuchi, Y | 1 |
| Numata, T | 1 |
| Tanaka, R | 1 |
| Yamane, Y | 1 |
| Yamamoto, T | 1 |
| Goto, T | 1 |
| Kishita, Y | 1 |
| Murayama, K | 1 |
| Ohtake, A | 1 |
| Okazaki, Y | 1 |
| Sakaguchi, Y | 1 |
| Shetewy, A | 1 |
| Shimada-Takaura, K | 1 |
| Warner, D | 1 |
| Mehdi, AB | 1 |
| Alexeyev, M | 1 |
| Takahashi, K | 1 |
| Wada, T | 1 |
| Saigo, K | 1 |
| Watanabe, K | 2 |
| Ohta, S | 1 |
| Umeda, N | 1 |
| Yukawa, M | 1 |
| Ohya, Y | 1 |
| Shindo, H | 1 |
| Palmi, M | 1 |
| Davey, G | 1 |
| Tipton, KF | 1 |
| Meini, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Taurine Supplementation and Physical Training Effects on Adipose Tissue Mitochondrial Energy Metabolism, and Blood Inflammation and Oxidative Stress in Obese Women[NCT04279600] | 24 participants (Actual) | Interventional | 2017-05-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for taurine and Mitochondrial Diseases
| Article | Year |
|---|---|
Posttranscriptional modifications in mitochondrial tRNA and its implication in mitochondrial translation and disease.
Topics: Animals; Humans; Mitochondria; Mitochondrial Diseases; RNA Processing, Post-Transcriptional; RNA, Tr | 2020 |
The Role of Taurine in Mitochondria Health: More Than Just an Antioxidant.
Topics: Animals; Antioxidants; Apoptosis; Clinical Trials as Topic; Humans; Mitochondria; Mitochondrial Dise | 2021 |
[Mitochondrial tRNA diseases: defect of modification in anticodon in mutant tRNA molecules].
Topics: Animals; Anticodon; Codon, Terminator; Humans; Mice; Mitochondrial Diseases; Mutation; RNA; RNA, Mit | 2003 |
7 other studies available for taurine and Mitochondrial Diseases
| Article | Year |
|---|---|
Mitochondrial haplotype mutation alleviates respiratory defect of MELAS by restoring taurine modification in tRNA with 3243A > G mutation.
Topics: DNA, Mitochondrial; Haplotypes; Humans; MELAS Syndrome; Mitochondrial Diseases; Mutation; RNA, Trans | 2023 |
Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease.
Topics: Humans; Mitochondrial Diseases; RNA, Transfer; Taurine | 2018 |
Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease.
Topics: Animals; Carrier Proteins; Cats; Child, Preschool; Female; GTP-Binding Proteins; HEK293 Cells; HeLa | 2018 |
Mitochondrial defects associated with β-alanine toxicity: relevance to hyper-beta-alaninemia.
Topics: Animals; beta-Alanine; Disorders of Excessive Somnolence; Electron Transport Complex I; Embryo, Mamm | 2016 |
Taurine as a constituent of mitochondrial tRNAs: new insights into the functions of taurine and human mitochondrial diseases.
Topics: Anticodon; Humans; Mass Spectrometry; Mitochondria; Mitochondrial Diseases; RNA, Transfer; Sequence | 2002 |
Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases.
Topics: Amino Acid Sequence; Carrier Proteins; Cell Respiration; GTP Phosphohydrolases; GTP-Binding Proteins | 2005 |
Taurine, taurine analogues, and mitochondrial function and dysfuntion.
Topics: Animals; Calcium; Cytochromes c; Male; Membrane Potentials; Mitochondria; Mitochondrial Diseases; Mo | 2006 |