Page last updated: 2024-10-20

taurine and Liver Neoplasms

taurine has been researched along with Liver Neoplasms in 23 studies

Liver Neoplasms: Tumors or cancer of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"NorUDCA (24-norursodeoxycholic acid), the C₂₃-homolog of ursodeoxycholic acid (UDCA), showed remarkable therapeutic effects in cholestatic Mdr2 (Abcb4) (multidrug resistance protein 2/ATP-binding cassette b4) knockout mice with sclerosing/fibrosing cholangitis."7.76Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver. ( Beuers, U; Denk, GU; Ferdinandusse, S; Fickert, P; Fuchsbichler, A; Hofmann, AF; Invernizzi, P; Kulik, W; Maitz, S; Rust, C; Trauner, M; Wimmer, R, 2010)
"Sorafenib (Sor) is a multi-kinase inhibitor."5.51Sorafenib- Taurine Combination Model for Hepatocellular Carcinoma Cells: Immunological Aspects. ( Afifi, AM; El-Houseini, ME; El-Husseiny, AM; Khalil, MA; Tabashy, RH, 2019)
"The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often correlated with tumor progression and poorer clinical outcomes."5.48Taurine up-regulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma. ( Chen, CY; Cheng, ML; Chi, HC; Chung, IH; Huang, YH; Lin, KH; Lin, YH; Tsai, CY; Wu, MH; Yeh, CT, 2018)
" Moreover, currently used chemotherapeutics have severe toxic side effects."5.38The antineoplastic antibiotic taurolidine promotes lung and liver metastasis in two syngeneic osteosarcoma mouse models and exhibits severe liver toxicity. ( Arlt, MJ; Banke, IJ; Bertz, J; Born, W; Ehrensperger, F; Fuchs, B; Puskas, GJ; Rentsch, KM; Steinmann, P; Walters, DK, 2012)
"Increasing evidence suggests that taurine upregulated gene 1 (TUG1) is crucial for tumor progression; however, its role in hepatocellular carcinoma (HCC) and the underlying mechanisms are not well characterized."4.12Exosomal lncRNA TUG1 from cancer-associated fibroblasts promotes liver cancer cell migration, invasion, and glycolysis by regulating the miR-524-5p/SIX1 axis. ( Da, X; Fan, M; Huang, J; Li, Q; Lu, H; Lu, L; Mo, J, 2022)
"NorUDCA (24-norursodeoxycholic acid), the C₂₃-homolog of ursodeoxycholic acid (UDCA), showed remarkable therapeutic effects in cholestatic Mdr2 (Abcb4) (multidrug resistance protein 2/ATP-binding cassette b4) knockout mice with sclerosing/fibrosing cholangitis."3.76Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver. ( Beuers, U; Denk, GU; Ferdinandusse, S; Fickert, P; Fuchsbichler, A; Hofmann, AF; Invernizzi, P; Kulik, W; Maitz, S; Rust, C; Trauner, M; Wimmer, R, 2010)
"Sorafenib (Sor) is a multi-kinase inhibitor."1.51Sorafenib- Taurine Combination Model for Hepatocellular Carcinoma Cells: Immunological Aspects. ( Afifi, AM; El-Houseini, ME; El-Husseiny, AM; Khalil, MA; Tabashy, RH, 2019)
"The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often correlated with tumor progression and poorer clinical outcomes."1.48Taurine up-regulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma. ( Chen, CY; Cheng, ML; Chi, HC; Chung, IH; Huang, YH; Lin, KH; Lin, YH; Tsai, CY; Wu, MH; Yeh, CT, 2018)
"Taurolidine (TRD) is a substance derived from the amino sulfonic acid taurine, which was originally used to treat peritonitis and catheter‑associated bloodstream infections, due to its antimicrobial and anti‑inflammatory properties."1.48Taurolidine promotes cell apoptosis by enhancing GRIM‑19 expression in liver cancer. ( Fu, Z; Li, F; Qi, J; Qin, C; Ren, W, 2018)
"The treatment of alcohol dependence (AD) is a complex activity as the variables are numerous; however, those which must necessarily be taken into account are the type of AD, the internal comorbidities and the presence of any psychiatric comorbidity."1.43Liver Disease and Hepatocellular Carcinoma in Alcoholics: The Role of Anticraving Therapy. ( Borro, P; Leone, S; Testino, G, 2016)
" Moreover, currently used chemotherapeutics have severe toxic side effects."1.38The antineoplastic antibiotic taurolidine promotes lung and liver metastasis in two syngeneic osteosarcoma mouse models and exhibits severe liver toxicity. ( Arlt, MJ; Banke, IJ; Bertz, J; Born, W; Ehrensperger, F; Fuchs, B; Puskas, GJ; Rentsch, KM; Steinmann, P; Walters, DK, 2012)
"Furthermore the number of liver metastasis per animal was reduced after lavage with taurolidin (2 +/- 2) and Octreotide (2."1.33Impact of taurolidin and octreotide on liver metastasis and lipid peroxidation after laparoscopy in chemical induced ductal pancreatic cancer. ( Braumann, C; Gregor, JI; Guski, H; Heukamp, I; Jacobi, CA; Kilian, M; Schimke, I; Walz, MK; Wenger, FA, 2005)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.04)18.7374
1990's3 (13.04)18.2507
2000's6 (26.09)29.6817
2010's9 (39.13)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Lu, L1
Huang, J1
Mo, J1
Da, X1
Li, Q1
Fan, M1
Lu, H1
Afifi, AM1
El-Husseiny, AM1
Tabashy, RH1
Khalil, MA1
El-Houseini, ME1
Nabi, AA1
Atta, SA1
El-Ahwany, E1
Elzayat, E1
Saleh, H1
Lin, YH1
Wu, MH1
Huang, YH1
Yeh, CT1
Cheng, ML1
Chi, HC1
Tsai, CY1
Chung, IH1
Chen, CY1
Lin, KH1
Li, F1
Qi, J1
Qin, C1
Fu, Z1
Ren, W1
Borro, P1
Leone, S1
Testino, G1
Denk, GU1
Maitz, S1
Wimmer, R1
Rust, C1
Invernizzi, P1
Ferdinandusse, S1
Kulik, W1
Fuchsbichler, A1
Fickert, P1
Trauner, M1
Hofmann, AF1
Beuers, U1
Arlt, MJ2
Walters, DK1
Banke, IJ1
Steinmann, P1
Puskas, GJ1
Bertz, J1
Rentsch, KM1
Ehrensperger, F1
Born, W2
Fuchs, B2
Braumann, C3
Pfirrmann, RW1
Abd-Rabou, AA1
Zoheir, KM1
Ahmed, HH1
SONGSTER, CL1
SCHOCHET, SS1
FARBER, E1
Junankar, PR1
Karjalainen, A1
Kirk, K1
Ito, T1
Fujio, Y1
Hirata, M1
Takatani, T1
Matsuda, T1
Muraoka, S1
Takahashi, K1
Azuma, J1
Kilian, M2
Gregor, JI1
Heukamp, I1
Guski, H2
Schimke, I1
Walz, MK1
Jacobi, CA2
Wenger, FA2
Park, SH2
Lee, H2
Park, KK2
Kim, HW2
Park, T2
Lee, DH1
Linnet, K1
Andersen, JR1
Láng, I1
Feuer, L1
Nèkám, K1
Török, K1
Kalmár, L1
Gergely, P1
Van den Hout, BM1
Taal, BG1
Gortzak, E1
Zoetmulder, FA1
Boot, H1
You, JS1
Chang, KJ1
Wördemann, M1
Fandrey, J1
Jelkmann, W1
Neumann, A1
Ridders, J1
Peter, FJ1

Other Studies

23 other studies available for taurine and Liver Neoplasms

ArticleYear
Exosomal lncRNA TUG1 from cancer-associated fibroblasts promotes liver cancer cell migration, invasion, and glycolysis by regulating the miR-524-5p/SIX1 axis.
    Cellular & molecular biology letters, 2022, Feb-22, Volume: 27, Issue:1

    Topics: Animals; Cancer-Associated Fibroblasts; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement;

2022
Sorafenib- Taurine Combination Model for Hepatocellular Carcinoma Cells: Immunological Aspects.
    Asian Pacific journal of cancer prevention : APJCP, 2019, Oct-01, Volume: 20, Issue:10

    Topics: Carcinoma, Hepatocellular; Cell Proliferation; Cytokines; Drug Therapy, Combination; Forkhead Transc

2019
Taurine Upregulates miRNA-122-5p Expression and Suppresses the Metabolizing Enzymes of Glycolytic Pathway in Hepatocellular Carcinoma.
    Molecular biology reports, 2021, Volume: 48, Issue:7

    Topics: Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationshi

2021
Taurine up-regulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:1

    Topics: Biopsy, Needle; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Gene Expression Regulation, Neo

2018
Taurolidine promotes cell apoptosis by enhancing GRIM‑19 expression in liver cancer.
    Oncology reports, 2018, Volume: 40, Issue:6

    Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cell Line, Tumor;

2018
Liver Disease and Hepatocellular Carcinoma in Alcoholics: The Role of Anticraving Therapy.
    Current drug targets, 2016, Volume: 17, Issue:2

    Topics: Acamprosate; Alcohol Deterrents; Alcoholics; Alcoholism; Baclofen; Carcinoma, Hepatocellular; Drug C

2016
Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver.
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:5

    Topics: Animals; Apoptosis; Bile; Bile Acids and Salts; Carcinoma, Hepatocellular; Cholangitis; Cholestasis;

2010
The antineoplastic antibiotic taurolidine promotes lung and liver metastasis in two syngeneic osteosarcoma mouse models and exhibits severe liver toxicity.
    International journal of cancer, 2012, Sep-01, Volume: 131, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Female

2012
Taurolidine: Mode of administration in mouse tumor models.
    International journal of cancer, 2012, Sep-15, Volume: 131, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Female

2012
Taurolidine: mode of administration in mouse tumor models.
    International journal of cancer, 2012, Dec-01, Volume: 131, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Female

2012
Potential impact of curcumin and taurine on human hepatoma cells using Huh-7 cell line.
    Clinical biochemistry, 2012, Volume: 45, Issue:16-17

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; CD4 Antigens; CD8 Antigens; Cell Line, Tumor; Cell

2012
METABOLISM OF BILE COMPONENTS DURING HEPATOCARCINOGENESIS. I. CONJUGATION OF CHOLIC ACID IN VITRO IN EXPERIMENTAL LIVER CARCINOGENESIS.
    Cancer research, 1963, Volume: 23

    Topics: Bile; Bile Acids and Salts; Carcinogenesis; Cholic Acid; Ethionine; Fluorenes; In Vitro Techniques;

1963
Osmotic swelling activates two pathways for K+ efflux in a rat hepatoma cell line.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2004, Volume: 14, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Liver Neoplasms; Osmolar Concentration; Osmosi

2004
Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells.
    The Biochemical journal, 2004, Aug-15, Volume: 382, Issue:Pt 1

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA, Neoplasm; Gene Expression

2004
Impact of taurolidin and octreotide on liver metastasis and lipid peroxidation after laparoscopy in chemical induced ductal pancreatic cancer.
    Investigational new drugs, 2005, Volume: 23, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Cricetinae; Laparoscop

2005
Taurine-responsive genes related to signal transduction as identified by cDNA microarray analyses of HepG2 cells.
    Journal of medicinal food, 2006,Spring, Volume: 9, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression; Gene Expression Profiling; Humans; Int

2006
Taurine-induced changes in transcription profiling of metabolism-related genes in human hepatoma cells HepG2.
    Advances in experimental medicine and biology, 2006, Volume: 583

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Energy Metabolism; Gene Expression Profiling;

2006
Differential diagnostic value in hepatobiliary disease of serum conjugated bile acid concentrations and some routine liver tests assessed by discriminant analysis.
    Clinica chimica acta; international journal of clinical chemistry, 1983, Jan-24, Volume: 127, Issue:2

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bi

1983
Effect of treatment with glutaurine on human antibody-dependent cell-mediated cytotoxicity (ADCC).
    Immunological communications, 1981, Volume: 10, Issue:6

    Topics: Adult; Aged; Animals; Antibody-Dependent Cell Cytotoxicity; Breast Neoplasms; Colonic Neoplasms; Fem

1981
Long-term survival in two cases of colorectal carcinoma following a new chemotherapy regimen and subsequent metastasectomy.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1995, Volume: 21, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms;

1995
Taurine protects the liver against lipid peroxidation and membrane disintegration during rat hepatocarcinogenesis.
    Advances in experimental medicine and biology, 1998, Volume: 442

    Topics: Animals; Carcinogens; Cell Membrane; Diethylnitrosamine; Glucose-6-Phosphatase; Glutathione Peroxida

1998
Tumor necrosis factor-alpha production by human hepatoma cell lines is resistant to drugs that are inhibitory to macrophages.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 1998, Volume: 18, Issue:12

    Topics: Adjuvants, Immunologic; Carcinoma, Hepatocellular; Cyclosporine; Drug Resistance, Neoplasm; Humans;

1998
Effects of taurolidine and octreotide on port site and liver metastasis after laparoscopy in an animal model of pancreatic cancer.
    Clinical & experimental metastasis, 2002, Volume: 19, Issue:2

    Topics: Animals; Antineoplastic Agents; Biopsy; Carcinoma, Pancreatic Ductal; Cricetinae; Diet; Laparoscopy;

2002