taurine has been researched along with Hepatic Encephalopathy in 25 studies
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the risk of hepatic encephalopathy and arterial hypotension in cirrhotic patients after acute administration of acamprosate, a GABA mimetic drug used in the weaned alcoholic, a randomized double-blind trial was conducted in 24 cirrhotic patients with low or moderate hepatic insufficiency (Pugh grade A or B)." | 9.07 | [Effect of acute administration of acamprosate on the risk of encephalopathy and on arterial pressure in patients with alcoholic cirrhosis]. ( Capron, D; Capron, JP; Delgrange, T; Duron, B; Khater, J, 1992) |
| "This study was to investigate the effects of ammonia and manganese in the metabolism of minimal hepatic encephalopathy (MHE)." | 8.31 | The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study. ( Li, Y; Liu, XF; Lu, JJ; Qiang, JW; Yang, XY, 2023) |
| " The current investigation was designed to evaluate the role of taurine treatment on the brain and liver mitochondrial function in a rat model of hepatic encephalopathy and hyperammonemia." | 7.85 | Taurine treatment preserves brain and liver mitochondrial function in a rat model of fulminant hepatic failure and hyperammonemia. ( Abasvali, M; Abdoli, N; Asadi, B; Azarpira, N; Heidari, R; Jafari, F; Jamshidzadeh, A; Khodaei, F; Latifpour, Z; Mardani, E; Najibi, A; Ommati, MM; Yeganeh, Y; Zarei, A; Zarei, M, 2017) |
| "The possible involvement of taurine in the pathogenesis of hepatic encephalopathy was studied in rats injected with thioacetamide." | 7.68 | Taurine release from brain slices in thioacetamide-induced hepatic encephalopathy in rats. ( Oja, SS; Saransaari, P; Wysmyk, U, 1991) |
| "By contrast, rats with hepatic encephalopathy (HE) following administration of a hepatotoxin, thioacetamide, were characterized by CC edema and an increased Tau content in both BG and CC." | 5.29 | Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure. ( Albrecht, J; Hilgier, W; Olson, JE, 1996) |
| "To evaluate the risk of hepatic encephalopathy and arterial hypotension in cirrhotic patients after acute administration of acamprosate, a GABA mimetic drug used in the weaned alcoholic, a randomized double-blind trial was conducted in 24 cirrhotic patients with low or moderate hepatic insufficiency (Pugh grade A or B)." | 5.07 | [Effect of acute administration of acamprosate on the risk of encephalopathy and on arterial pressure in patients with alcoholic cirrhosis]. ( Capron, D; Capron, JP; Delgrange, T; Duron, B; Khater, J, 1992) |
| "This study was to investigate the effects of ammonia and manganese in the metabolism of minimal hepatic encephalopathy (MHE)." | 4.31 | The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study. ( Li, Y; Liu, XF; Lu, JJ; Qiang, JW; Yang, XY, 2023) |
| " The current investigation was designed to evaluate the role of taurine treatment on the brain and liver mitochondrial function in a rat model of hepatic encephalopathy and hyperammonemia." | 3.85 | Taurine treatment preserves brain and liver mitochondrial function in a rat model of fulminant hepatic failure and hyperammonemia. ( Abasvali, M; Abdoli, N; Asadi, B; Azarpira, N; Heidari, R; Jafari, F; Jamshidzadeh, A; Khodaei, F; Latifpour, Z; Mardani, E; Najibi, A; Ommati, MM; Yeganeh, Y; Zarei, A; Zarei, M, 2017) |
| " decreases by 25% the high (50 mM) K+-evoked accumulation of Tau in striatal microdialysates of healthy rats and by 34% in rats with thioacetamide-induced hepatic failure, where the increased extracellular accumulation of Tau signifies ongoing hepatic encephalopathy." | 3.71 | Lubeluzole attenuates K(+)-evoked extracellular accumulation of taurine in the striatum of healthy rats and rats with hepatic failure. ( Albrecht, J; Borkowska, HD; Hilgier, W; Oja, SS; Saransaari, P; Zielińska, M, 2001) |
| "Rats were treated with a hepatotoxin thioacetamide (TAA) and examined 21 days later, when they showed moderate fatty metamorphosis of the liver and morphological changes in brain indicative of excitotoxic neuronal damage, but no evident biochemical or neurophysiological symptoms of hepatic encephalopathy (HE)." | 3.70 | Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure. ( Albrecht, J; Borkowska, HD; Gadamski, R; Hilgier, W; Oja, SS; Saransaari, P; Walski, M; Zielińska, M, 1999) |
| "The possible involvement of taurine in the pathogenesis of hepatic encephalopathy was studied in rats injected with thioacetamide." | 3.68 | Taurine release from brain slices in thioacetamide-induced hepatic encephalopathy in rats. ( Oja, SS; Saransaari, P; Wysmyk, U, 1991) |
| "Taurine (Tau) is an amino acid that is thought to mimic GABA function because of its agonistic properties towards GABA(A) receptors, and to contribute to neuroprotection and osmoregulation." | 2.41 | The role of inhibitory amino acidergic neurotransmission in hepatic encephalopathy: a critical overview. ( Albrecht, J; Zielińska, M, 2002) |
| "Myo-inositol levels were strongly decreased already at 3h after treatment with NH4Cl; other intracellular osmolytes, such as hypotaurine and choline-containing compounds were also decreased, along with a concomitant increase of both the total concentration and the amount of newly synthesized glutamine, alanine, and glutathione." | 1.33 | Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response. ( Leibfritz, D; Zwingmann, C, 2005) |
| "By contrast, rats with hepatic encephalopathy (HE) following administration of a hepatotoxin, thioacetamide, were characterized by CC edema and an increased Tau content in both BG and CC." | 1.29 | Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure. ( Albrecht, J; Hilgier, W; Olson, JE, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 8 (32.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Claeys, W | 1 |
| Van Hoecke, L | 1 |
| Geerts, A | 1 |
| Van Vlierberghe, H | 1 |
| Lefere, S | 1 |
| Van Imschoot, G | 1 |
| Van Wonterghem, E | 1 |
| Ghesquière, B | 1 |
| Vandenbroucke, RE | 1 |
| Van Steenkiste, C | 1 |
| Liu, XF | 1 |
| Lu, JJ | 1 |
| Li, Y | 1 |
| Yang, XY | 1 |
| Qiang, JW | 1 |
| Schnelle, ANW | 1 |
| Richardson, LT | 1 |
| Pettit, ME | 1 |
| DeMorrow, S | 1 |
| Solouki, T | 1 |
| Ahmadi, N | 1 |
| Ghanbarinejad, V | 1 |
| Ommati, MM | 2 |
| Jamshidzadeh, A | 2 |
| Heidari, R | 3 |
| Abasvali, M | 1 |
| Zarei, M | 1 |
| Abdoli, N | 1 |
| Khodaei, F | 1 |
| Yeganeh, Y | 1 |
| Jafari, F | 1 |
| Zarei, A | 1 |
| Latifpour, Z | 1 |
| Mardani, E | 1 |
| Azarpira, N | 1 |
| Asadi, B | 1 |
| Najibi, A | 1 |
| Singhal, A | 1 |
| Nagarajan, R | 1 |
| Kumar, R | 1 |
| Huda, A | 1 |
| Gupta, RK | 1 |
| Thomas, MA | 1 |
| Bodega, G | 1 |
| Suárez, I | 1 |
| López-Fernández, LA | 1 |
| García, MI | 1 |
| Köber, M | 1 |
| Penedo, M | 1 |
| Luna, M | 1 |
| Juárez, S | 1 |
| Ciordia, S | 1 |
| Oria, M | 1 |
| Córdoba, J | 1 |
| Fernández, B | 1 |
| Albrecht, J | 5 |
| Zielińska, M | 4 |
| Zwingmann, C | 2 |
| Chatauret, N | 1 |
| Rose, C | 1 |
| Leibfritz, D | 2 |
| Butterworth, RF | 3 |
| Chepkova, AN | 1 |
| Sergeeva, OA | 1 |
| Haas, HL | 1 |
| Rao, VL | 1 |
| Audet, RM | 1 |
| Hilgier, W | 4 |
| Olson, JE | 1 |
| Morsiani, E | 1 |
| Pazzi, P | 1 |
| Moscioni, AD | 1 |
| Rozga, J | 1 |
| Azzena, G | 1 |
| Demetriou, AA | 1 |
| Borkowska, HD | 2 |
| Gadamski, R | 1 |
| Walski, M | 1 |
| Oja, SS | 3 |
| Saransaari, P | 3 |
| Law, RO | 1 |
| Smith, AR | 1 |
| Rossi-Fanelli, F | 1 |
| Freund, H | 1 |
| Fischer, JE | 1 |
| Delgrange, T | 1 |
| Khater, J | 1 |
| Capron, D | 1 |
| Duron, B | 1 |
| Capron, JP | 1 |
| Wysmyk, U | 1 |
| Maddison, JE | 1 |
| Leong, DK | 1 |
| Dodd, PR | 1 |
| Johnston, GA | 1 |
| Benjamin, LE | 1 |
| Steele, RD | 1 |
| Verzetti, G | 1 |
| Emanuelli, G | 1 |
| Montagnani, M | 1 |
3 reviews available for taurine and Hepatic Encephalopathy
| Article | Year |
|---|---|
Brain mitochondria as potential therapeutic targets for managing hepatic encephalopathy.
Topics: Animals; Brain; Brain Injuries; Energy Metabolism; Hepatic Encephalopathy; Humans; Hyperammonemia; M | 2019 |
The role of inhibitory amino acidergic neurotransmission in hepatic encephalopathy: a critical overview.
Topics: Amino Acids; Animals; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Models, Neurological; Neural | 2002 |
Taurine in hepatic encephalopathy.
Topics: Animals; Biomarkers; Brain; Brain Edema; Hepatic Encephalopathy; Humans; Intracranial Pressure; Live | 1996 |
1 trial available for taurine and Hepatic Encephalopathy
| Article | Year |
|---|---|
[Effect of acute administration of acamprosate on the risk of encephalopathy and on arterial pressure in patients with alcoholic cirrhosis].
Topics: Acamprosate; Administration, Oral; Adult; Blood Pressure; Double-Blind Method; Drug Evaluation; Evok | 1992 |
21 other studies available for taurine and Hepatic Encephalopathy
| Article | Year |
|---|---|
A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.
Topics: Ammonia; Animals; Bile Acids and Salts; Bile Ducts; Brain; Choline; Disease Models, Animal; Glutamin | 2022 |
The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study.
Topics: Alanine; Ammonia; Animals; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glut | 2023 |
Trihydroxycholanoyl-taurine in brains of rodents with hepatic encephalopathy.
Topics: Animals; Bile Acids and Salts; Chromatography, High Pressure Liquid; Hepatic Encephalopathy; Isomeri | 2021 |
Taurine prevents mitochondrial membrane permeabilization and swelling upon interaction with manganese: Implication in the treatment of cirrhosis-associated central nervous system complications.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Brain; Hepatic Encephalopathy; Kinetics; Male; Mangan | 2018 |
Taurine treatment preserves brain and liver mitochondrial function in a rat model of fulminant hepatic failure and hyperammonemia.
Topics: Adenosine Triphosphate; Ammonia; Animals; Brain; Hepatic Encephalopathy; Hyperammonemia; Liver; Live | 2017 |
Magnetic resonance T2-relaxometry and 2D L-correlated spectroscopy in patients with minimal hepatic encephalopathy.
Topics: Adult; Aged; Brain; Choline; Creatine; Female; Hepatic Encephalopathy; Humans; Inositol; Liver; Magn | 2009 |
Ammonia induces aquaporin-4 rearrangement in the plasma membrane of cultured astrocytes.
Topics: alpha-Synuclein; Ammonia; Animals; Aquaporin 4; Astrocytes; Brain Edema; Cell Membrane; Cells, Cultu | 2012 |
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia.
Topics: Animals; Brain Edema; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Hypothermia, Induce | 2004 |
Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response.
Topics: Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Animals, Newborn; Astrocytes; Brain Edema | 2005 |
Taurine rescues hippocampal long-term potentiation from ammonia-induced impairment.
Topics: Ammonium Chloride; Animals; Carnitine; Energy Metabolism; Hepatic Encephalopathy; Hippocampus; Hyper | 2006 |
Selective alterations of extracellular brain amino acids in relation to function in experimental portal-systemic encephalopathy: results of an in vivo microdialysis study.
Topics: Acetates; Alanine; Amino Acids; Animals; Brain; Dialysis; Extracellular Space; Frontal Lobe; Glutami | 1995 |
Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure.
Topics: Ammonia; Animals; Basal Ganglia; Body Water; Brain Edema; Cerebral Cortex; Hepatic Encephalopathy; I | 1996 |
In vitro morphological and functional characterization of isolated porcine hepatocytes for extracorporeal liver support: bile acid uptake and conjugation.
Topics: Animals; Bile Acids and Salts; Cells, Cultured; Female; Glycine; Hepatic Encephalopathy; Humans; Liv | 1998 |
Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Biological Transport; Corpus Striatum; Excitatory Amin | 1999 |
Lubeluzole attenuates K(+)-evoked extracellular accumulation of taurine in the striatum of healthy rats and rats with hepatic failure.
Topics: Animals; Extracellular Space; Glutamic Acid; Hepatic Encephalopathy; Male; Microdialysis; Neostriatu | 2001 |
Taurine, glutamine, glutamate, and aspartate content and efflux, and cell volume of cerebrocortical minislices of rats with hepatic encephalopathy: influence of ammonia.
Topics: Ammonia; Animals; Aspartic Acid; Cell Size; Cerebral Cortex; Glutamic Acid; Glutamine; Hepatic Encep | 2000 |
Sulfur-containing amino acids in experimental hepatic coma in the dog and the monkey.
Topics: Amino Acids, Branched-Chain; Amino Acids, Sulfur; Animals; Brain Chemistry; Disease Models, Animal; | 1979 |
Taurine release from brain slices in thioacetamide-induced hepatic encephalopathy in rats.
Topics: Ammonia; Ammonium Chloride; Animals; Brain Chemistry; Corpus Striatum; Hepatic Encephalopathy; Male; | 1991 |
Plasma GABA-like activity in rats with hepatic encephalopathy is due to GABA and taurine.
Topics: Animals; Binding, Competitive; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutam | 1990 |
The effect of dietary protein on nitrogen and sulfur metabolism in portacaval-shunted rats.
Topics: Amino Acids, Sulfur; Ammonia; Animals; Body Weight; Dietary Proteins; Hepatic Encephalopathy; Liver; | 1986 |
[Therapy of hyperammonemia: effect of a preparation arginine pyrrolidonecarboxylate, taurine, vitamin B6 and citric acid].
Topics: Amino Acids; Ammonia; Arginine; Brain Diseases; Citrates; Drug Combinations; Hepatic Encephalopathy; | 1972 |