taurine has been researched along with Glial Cell Tumors in 38 studies
Excerpt | Relevance | Reference |
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" In this study we analyzed resected tissue metabolites using capillary electrophoresis-mass spectrometry and found that tissue hypotaurine levels strongly and positively correlated with glioma grade." | 7.83 | Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling. ( Chu, H; Feldman, MJ; Gao, P; Heiss, JD; Li, G; Liu, H; Liu, Y; Nesvick, CL; Sizdahkhani, S; Tang, L; Tian, J; Xu, G; Yang, C; Yang, F; Zhao, S; Zhuang, Z, 2016) |
" In the cytotoxicity assay 100% of glioma cell lines (eight of eight) and 74% of ex vivo glioma cultures (14 of 19) demonstrated sensitivity to taurolidine, with a mean median effective concentration (EC50) of 51 +/- 28 microg/ml and 56 +/- 23 microg/ml, respectively." | 7.73 | Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine. ( Eugster, HP; Frei, K; Ishihara, H; Könü, D; Kubota, H; Möhler, H; Rodak, R; Yonekawa, Y, 2005) |
"Taurine concentrations were determined in gliomas from 16 patients and in meningiomas from 15 patients." | 7.73 | Taurine concentration in human gliomas and meningiomas: tumoral, peritumoral, and extratumoral tissue. ( Cubillos, S; Lima, L; Obregón, F; Salazar, LA; Vargas, MF, 2006) |
"The transport of taurine into membrane vesicles prepared from neuroblastoma x glioma hybrid cells 108CC5 was studied." | 7.67 | Na+-dependent transport of taurine by membrane vesicles of neuroblastoma x glioma hybrid cells. ( Hamprecht, B; Yuasa, S, 1987) |
"The effects of triethyltin (TET) on the transport of taurine, glutamate, lysine, Na+, K+ (using 86Rb+ as tracer), and Cl- by LRM55 glioma cells were examined." | 7.66 | Inhibitory effect of triethyltin on taurine transport by glioma cells. ( Martin, DL; Waniewski, RA; Wolpaw, EW, 1983) |
"In neuroblastoma x glioma hybrid cells, a cell line of neuronal character, a saturable uptake system for taurine is found which displays high affinity and high capacity (km = 38 micro M, V = 1." | 7.66 | Na+-dependent uptake and release of taurine by neuroblastoma x glioma hybrid cells. ( Hamprecht, B; Kürzinger, K, 1981) |
"Glioma is one of the most lethal brain malignancies with unknown etiologies." | 5.46 | Capillary electrophoresis - Mass spectrometry metabolomics analysis revealed enrichment of hypotaurine in rat glioma tissues. ( Cao, Y; Fang, X; Gao, P; Ji, M; Liu, Y; Sun, A; Yu, Z; Zhang, Y; Zhao, L, 2017) |
"Taurine is an antioxidant." | 5.39 | Protective effect of taurine on triorthocresyl phosphate (TOCP)-induced cytotoxicity in C6 glioma cells. ( Li, Y; Liu, X; Piao, F, 2013) |
"Taurine was found to significantly correlate with apoptotic cell density (TUNEL) in both non-necrotic (R=0." | 5.35 | Taurine: a potential marker of apoptosis in gliomas. ( Bell, BA; Griffiths, JR; Howe, FA; Opstad, KS, 2009) |
" In this study we analyzed resected tissue metabolites using capillary electrophoresis-mass spectrometry and found that tissue hypotaurine levels strongly and positively correlated with glioma grade." | 3.83 | Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling. ( Chu, H; Feldman, MJ; Gao, P; Heiss, JD; Li, G; Liu, H; Liu, Y; Nesvick, CL; Sizdahkhani, S; Tang, L; Tian, J; Xu, G; Yang, C; Yang, F; Zhao, S; Zhuang, Z, 2016) |
"A previous study showed that treatment of C6 glioma cells with 10 mM ammonium chloride monia") for 24 h decreases taurine uptake and evokes sodium-dependent taurine efflux, indicating reversal of the taurine transporter (TauT)-mediated transport as an underlying mechanism." | 3.73 | The role of protein kinase C and cyclic AMP in the ammonia-induced shift of the taurine uptake/efflux balance towards efflux in C6 cells. ( Albrecht, J; Dybel, A; Zabłocka, B; Zielińska, M, 2005) |
" In the cytotoxicity assay 100% of glioma cell lines (eight of eight) and 74% of ex vivo glioma cultures (14 of 19) demonstrated sensitivity to taurolidine, with a mean median effective concentration (EC50) of 51 +/- 28 microg/ml and 56 +/- 23 microg/ml, respectively." | 3.73 | Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine. ( Eugster, HP; Frei, K; Ishihara, H; Könü, D; Kubota, H; Möhler, H; Rodak, R; Yonekawa, Y, 2005) |
"Taurine concentrations were determined in gliomas from 16 patients and in meningiomas from 15 patients." | 3.73 | Taurine concentration in human gliomas and meningiomas: tumoral, peritumoral, and extratumoral tissue. ( Cubillos, S; Lima, L; Obregón, F; Salazar, LA; Vargas, MF, 2006) |
" The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
" The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
"C6 glioma cells accumulate the organic osmolyte inositol in response to chronic hypertonic stress." | 3.68 | Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux. ( Jackson, PS; Strange, K, 1993) |
"The transport of taurine into membrane vesicles prepared from neuroblastoma x glioma hybrid cells 108CC5 was studied." | 3.67 | Na+-dependent transport of taurine by membrane vesicles of neuroblastoma x glioma hybrid cells. ( Hamprecht, B; Yuasa, S, 1987) |
"The effects of triethyltin (TET) on the transport of taurine, glutamate, lysine, Na+, K+ (using 86Rb+ as tracer), and Cl- by LRM55 glioma cells were examined." | 3.66 | Inhibitory effect of triethyltin on taurine transport by glioma cells. ( Martin, DL; Waniewski, RA; Wolpaw, EW, 1983) |
"In neuroblastoma x glioma hybrid cells, a cell line of neuronal character, a saturable uptake system for taurine is found which displays high affinity and high capacity (km = 38 micro M, V = 1." | 3.66 | Na+-dependent uptake and release of taurine by neuroblastoma x glioma hybrid cells. ( Hamprecht, B; Kürzinger, K, 1981) |
"46 eligible patients with either anaplastic astrocytoma (AA) or glioblastoma (GBM) and clinical and computed-tomography-confirmed relapse following primary surgery and radiotherapy received oral tauromustine 130 mg/m2 every 5 weeks." | 2.67 | Phase II study of tauromustine in malignant glioma. ( Aapro, M; Demierre, B; Gregor, A; Ironside, JW; Malmström, P; Rampling, R; Rye, R; Sellar, R; Stewart, M; Whittle, IR, 1992) |
"Glioma is one of the most lethal brain malignancies with unknown etiologies." | 1.46 | Capillary electrophoresis - Mass spectrometry metabolomics analysis revealed enrichment of hypotaurine in rat glioma tissues. ( Cao, Y; Fang, X; Gao, P; Ji, M; Liu, Y; Sun, A; Yu, Z; Zhang, Y; Zhao, L, 2017) |
"Taurine is an antioxidant." | 1.39 | Protective effect of taurine on triorthocresyl phosphate (TOCP)-induced cytotoxicity in C6 glioma cells. ( Li, Y; Liu, X; Piao, F, 2013) |
"Taurine was found to significantly correlate with apoptotic cell density (TUNEL) in both non-necrotic (R=0." | 1.35 | Taurine: a potential marker of apoptosis in gliomas. ( Bell, BA; Griffiths, JR; Howe, FA; Opstad, KS, 2009) |
"High-grade brain tumors are known to have a high rate of glucose (Glc) consumption." | 1.31 | High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging. ( Décorps, M; Rémy, C; von Kienlin , M; Ziegler, A, 2001) |
" The absolute levels of TCNU obtained with a dose of 100 mg TCNU/kg bodyweight were at most time points, three to four times those obtained with dosage of 25 mg TCNU/kg." | 1.27 | Experimental cerebral and plasma pharmacokinetic studies of TCNU: implications for brain tumour chemotherapy. ( Macpherson, JS; Miller, JD; Smyth, J; Whittle, IR, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (28.95) | 18.7374 |
1990's | 10 (26.32) | 18.2507 |
2000's | 10 (26.32) | 29.6817 |
2010's | 7 (18.42) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Gao, P | 2 |
Ji, M | 1 |
Fang, X | 1 |
Liu, Y | 4 |
Yu, Z | 1 |
Cao, Y | 1 |
Sun, A | 1 |
Zhao, L | 1 |
Zhang, Y | 1 |
Zawaski, JA | 1 |
Sabek, OM | 1 |
Voicu, H | 1 |
Eastwood Leung, HC | 1 |
Gaber, MW | 1 |
García-Álvarez, I | 1 |
Garrido, L | 1 |
Romero-Ramírez, L | 1 |
Nieto-Sampedro, M | 1 |
Fernández-Mayoralas, A | 1 |
Campos-Olivas, R | 1 |
Yang, C | 1 |
Nesvick, CL | 1 |
Feldman, MJ | 1 |
Sizdahkhani, S | 1 |
Liu, H | 1 |
Chu, H | 1 |
Yang, F | 1 |
Tang, L | 1 |
Tian, J | 1 |
Zhao, S | 1 |
Li, G | 1 |
Heiss, JD | 1 |
Zhuang, Z | 1 |
Xu, G | 1 |
Opstad, KS | 1 |
Bell, BA | 1 |
Griffiths, JR | 1 |
Howe, FA | 1 |
Robert, O | 1 |
Sabatier, J | 1 |
Desoubzdanne, D | 1 |
Lalande, J | 1 |
Balayssac, S | 1 |
Gilard, V | 1 |
Martino, R | 1 |
Malet-Martino, M | 1 |
Zhou, J | 1 |
Li, Y | 2 |
Yan, G | 1 |
Bu, Q | 1 |
Lv, L | 1 |
Yang, Y | 1 |
Zhao, J | 1 |
Shao, X | 1 |
Deng, Y | 1 |
Zhu, R | 1 |
Zhao, Y | 1 |
Cen, X | 1 |
Piao, F | 1 |
Liu, X | 1 |
Lehtimäki, KK | 1 |
Valonen, PK | 1 |
Griffin, JL | 1 |
Väisänen, TH | 1 |
Gröhn, OH | 1 |
Kettunen, MI | 1 |
Vepsäläinen, J | 1 |
Ylä-Herttuala, S | 1 |
Nicholson, J | 1 |
Kauppinen, RA | 1 |
Ordaz, B | 1 |
Vaca, L | 1 |
Franco, R | 1 |
Pasantes-Morales, H | 1 |
Tong, Z | 2 |
Yamaki, T | 2 |
Harada, K | 2 |
Houkin, K | 2 |
Zielińska, M | 1 |
Zabłocka, B | 1 |
Dybel, A | 1 |
Albrecht, J | 1 |
Rodak, R | 1 |
Kubota, H | 1 |
Ishihara, H | 1 |
Eugster, HP | 1 |
Könü, D | 1 |
Möhler, H | 1 |
Yonekawa, Y | 1 |
Frei, K | 1 |
Cubillos, S | 1 |
Obregón, F | 1 |
Vargas, MF | 1 |
Salazar, LA | 1 |
Lima, L | 1 |
Hamprecht, B | 3 |
Martin, DL | 2 |
Waniewski, RA | 1 |
Wolpaw, EW | 1 |
Kürzinger, K | 1 |
Rebel, G | 2 |
Petegnief, V | 1 |
Lleu, PL | 1 |
Gupta, RC | 1 |
Guérin, P | 1 |
Bourguignon, J | 1 |
Rémy, C | 2 |
Arús, C | 1 |
Ziegler, A | 2 |
Lai, ES | 1 |
Moreno, A | 1 |
Le Fur, Y | 1 |
Décorps, M | 2 |
Jackson, PS | 1 |
Strange, K | 2 |
Clark, EC | 1 |
Thomas, D | 1 |
Baer, J | 1 |
Sterns, RH | 1 |
Nakamura, H | 1 |
Huang, SH | 1 |
Takakura, K | 1 |
Emma, F | 1 |
McManus, M | 1 |
Tonna-DeMasi, M | 1 |
Park, E | 1 |
Schuller-Levis, G | 2 |
Quinn, MR | 2 |
Lelong, IH | 1 |
von Kienlin , M | 1 |
De Micheli, E | 1 |
Alfieri, A | 1 |
Pinna, G | 1 |
Bianchi, L | 1 |
Colivicchi, MA | 1 |
Melani, A | 1 |
Pedata, F | 1 |
Della Corte, L | 1 |
Bricolo, A | 1 |
Henn, FA | 1 |
Shain, W | 2 |
Wheler, GH | 1 |
Bradford, HF | 1 |
Davison, AN | 1 |
Thompson, EJ | 2 |
Sieghart, W | 1 |
Karobath, M | 1 |
Gregor, A | 1 |
Rampling, R | 1 |
Aapro, M | 1 |
Malmström, P | 1 |
Whittle, IR | 2 |
Rye, R | 1 |
Stewart, M | 1 |
Sellar, R | 1 |
Demierre, B | 1 |
Ironside, JW | 1 |
Perrone, MH | 1 |
Lepore, RD | 1 |
Macpherson, JS | 1 |
Smyth, J | 1 |
Miller, JD | 1 |
Yuasa, S | 1 |
Schrier, BK | 1 |
1 trial available for taurine and Glial Cell Tumors
Article | Year |
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Phase II study of tauromustine in malignant glioma.
Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Drug Administration Schedule; Drug Evalu | 1992 |
37 other studies available for taurine and Glial Cell Tumors
Article | Year |
---|---|
Capillary electrophoresis - Mass spectrometry metabolomics analysis revealed enrichment of hypotaurine in rat glioma tissues.
Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Brain Neoplasms; Cell Line, Tumor; Electroph | 2017 |
Effect of Brain Tumor Presence During Radiation on Tissue Toxicity: Transcriptomic and Metabolic Changes.
Topics: Allografts; Animals; Biopsy; Brain; Brain Neoplasms; gamma-Aminobutyric Acid; Gene Expression Profil | 2017 |
The effect of antitumor glycosides on glioma cells and tissues as studied by proton HR-MAS NMR spectroscopy.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferati | 2013 |
Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling.
Topics: Animals; Apoptosis; Brain; Case-Control Studies; Cell Cycle; Cell Proliferation; Follow-Up Studies; | 2016 |
Taurine: a potential marker of apoptosis in gliomas.
Topics: Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Count; Glioma; Humans; In Situ Nick-End Labeling | 2009 |
pH optimization for a reliable quantification of brain tumor cell and tissue extracts with (1)H NMR: focus on choline-containing compounds and taurine.
Topics: Brain; Brain Chemistry; Brain Neoplasms; Choline; Glioma; Humans; Hydrogen-Ion Concentration; Magnet | 2011 |
Protective role of taurine against morphine-induced neurotoxicity in C6 cells via inhibition of oxidative stress.
Topics: Analysis of Variance; Animals; Apoptosis; Bicuculline; Caspase 3; Catalase; Cell Line, Tumor; Cell S | 2011 |
Protective effect of taurine on triorthocresyl phosphate (TOCP)-induced cytotoxicity in C6 glioma cells.
Topics: Animals; Cell Death; Cell Line, Tumor; Cell Shape; Cell Survival; Glioma; Glutathione; Glutathione P | 2013 |
Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.
Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Choline; Diffusion; Ganciclovir; Genet | 2003 |
Volume changes and whole cell membrane currents activated during gradual osmolarity decrease in C6 glioma cells: contribution of two types of K+ channels.
Topics: Animals; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Membrane; Cell Size; Chloride Channels; | 2004 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; C | 2004 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adult; Aged; Aspartic Acid; Body Water; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Cr | 2004 |
The role of protein kinase C and cyclic AMP in the ammonia-induced shift of the taurine uptake/efflux balance towards efflux in C6 cells.
Topics: Ammonia; Animals; Brain Neoplasms; Bucladesine; Cell Line, Tumor; Cyclic AMP; Enzyme Activators; Gli | 2005 |
Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Brain Neoplasms; | 2005 |
Taurine concentration in human gliomas and meningiomas: tumoral, peritumoral, and extratumoral tissue.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Glioma; Humans; Image Processing, Computer-Assisted; Male; | 2006 |
Cell culture as models for studying neural functions.
Topics: Animals; Animals, Newborn; Bradykinin; Cell Membrane Permeability; Cells, Cultured; Clone Cells; Cyc | 1984 |
Inhibitory effect of triethyltin on taurine transport by glioma cells.
Topics: Biological Transport; Cell Line; Glioma; Ouabain; Sodium; Taurine; Trialkyltin Compounds; Triethylti | 1983 |
Na+-dependent uptake and release of taurine by neuroblastoma x glioma hybrid cells.
Topics: Amino Acids; Animals; Biological Transport; Glioma; Hybrid Cells; Kinetics; Neuroblastoma; Ouabain; | 1981 |
New data on the regulation of taurine uptake in cultured nervous cells.
Topics: Animals; beta-Alanine; Cells, Cultured; Culture Media; gamma-Aminobutyric Acid; Glioma; Neuroglia; R | 1994 |
In vivo, ex vivo, and in vitro one- and two-dimensional nuclear magnetic resonance spectroscopy of an intracerebral glioma in rat brain: assignment of resonances.
Topics: Amino Acids; Animals; Brain; Brain Neoplasms; Choline; Fatty Acids, Nonesterified; Glioma; Lactates; | 1994 |
Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux.
Topics: Animals; Biological Transport; Cell Line; Chloride Channels; Chlorides; Fatty Acids, Nonesterified; | 1993 |
Depletion of glutathione from brain cells in hyponatremia.
Topics: Animals; Antioxidants; Brain; Brain Chemistry; Glioma; Glutathione; Humans; Hyponatremia; Male; Neur | 1996 |
High-affinity taurine uptake and its regulation by protein kinase C in human glioma cells.
Topics: Amino Acids; Biological Transport; Cell Line; Glioma; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Pr | 1996 |
Intracellular electrolytes regulate the volume set point of the organic osmolyte/anion channel VSOAC.
Topics: Animals; Chlorides; Glioma; Homeostasis; Hypertonic Solutions; Hypotonic Solutions; Intracellular Fl | 1997 |
Taurine chloramine inhibits production of nitric oxide and prostaglandin E2 in activated C6 glioma cells by suppressing inducible nitric oxide synthase and cyclooxygenase-2 expression.
Topics: Animals; Blotting, Northern; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Gene | 1998 |
In vitro taurine uptake into cell culture influenced by using media with or without CO2.
Topics: Adrenergic beta-Agonists; Brain Neoplasms; Buffers; Carbon Dioxide; Cell Division; Cell Line; Cells, | 1998 |
Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 production is inhibited by taurine chloramine in rat C6 glioma cells.
Topics: Animals; Chemokine CCL4; Chemokine CXCL2; Glioma; Inflammation Mediators; Macrophage Inflammatory Pr | 1999 |
High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging.
Topics: Alanine; Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Ethanolamines; Female; Glioma; | 2001 |
Extracellular levels of taurine in tumoral, peritumoral and normal brain tissue in patients with malignant glioma: an intraoperative microdialysis study.
Topics: Amino Acids; Brain; Brain Neoplasms; Extracellular Space; Female; Glioblastoma; Glioma; Humans; Male | 2000 |
Neurotransmission and glial cells: a functional relationship?
Topics: Amino Acids; Animals; Biological Transport, Active; Brain; Calcium; gamma-Aminobutyric Acid; Glioma; | 1976 |
High affinity transport of taurine and beta-alanine and low affinity transport of gamma-aminobutyric acid by a single transport system in cultured glioma cells.
Topics: Alanine; Animals; Biological Transport; Cell Line; gamma-Aminobutyric Acid; Glioma; Kinetics; Rats; | 1979 |
Uptake and release of taurine from cerebral cortex slices and their subcellular compartments.
Topics: Animals; Biological Transport; Calcium; Cell Line; Cerebral Cortex; Electric Stimulation; Female; ga | 1979 |
Uptake of taurine into subcellular fractions of C-6 glioma cells.
Topics: Alanine; Animals; Biological Transport, Active; Cell Line; Cerebral Cortex; Cyanides; Dinitrophenols | 1976 |
Identification and characterization of substance P receptors on LRM55 glial cells.
Topics: Animals; Cell Line; Cyclic AMP; Glioma; Kinetics; Neuroglia; Peptide Fragments; Rats; Receptors, Adr | 1986 |
Experimental cerebral and plasma pharmacokinetic studies of TCNU: implications for brain tumour chemotherapy.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Glioma; Male; Nitrosourea Compounds; Rats; Rats, In | 1987 |
Na+-dependent transport of taurine by membrane vesicles of neuroblastoma x glioma hybrid cells.
Topics: Animals; Biological Transport; Cell Line; Cell Membrane; Glioma; Hybrid Cells; Kinetics; Mice; Neuro | 1987 |
On the role of glial cells in the mammalian nervous system. Uptake, excretion, and metabolism of putative neurotransmitters by cultured glial tumor cells.
Topics: Alanine; Alkaloids; Alkanesulfonates; Amino Acids; Aminobutyrates; Animals; Brain; Carbon Dioxide; C | 1974 |