taurine has been researched along with Glaucoma in 10 studies
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether taurine and glutamate contents are reduced in damaged photoreceptors in dogs with primary glaucoma (PG) in a manner consistent with an ischemia-like release of both of these amino acids from damaged cells." | 7.73 | Depletion of taurine and glutamate from damaged photoreceptors in the retinas of dogs with primary glaucoma. ( Gionfriddo, JR; Madl, JE; McIlnay, TR; Powell, CC, 2005) |
| "Endothelin-1 (ET-1), a potent vasoconstrictor, plays a significant role in the pathophysiology of ocular conditions like glaucoma." | 3.96 | Magnesium acetyltaurate protects against endothelin-1 induced RGC loss by reducing neuroinflammation in Sprague dawley rats. ( Agarwal, P; Agarwal, R; Iezhitsa, I; Ismail, NM; Nor Arfuzir, NN, 2020) |
| " The purpose of this study was to evaluate the neuroprotective potential of RGC death induced by the in vivo transient increase in intraocular pressure (IOP) of a combined treatment with forskolin, homotaurine, and L-carnosine." | 3.81 | Intravitreal injection of forskolin, homotaurine, and L-carnosine affords neuroprotection to retinal ganglion cells following retinal ischemic injury. ( Adornetto, A; Bagetta, G; Cavaliere, F; Corasaniti, MT; Morrone, LA; Nucci, C; Rusciano, D; Russo, R; Varano, GP, 2015) |
| "To determine whether taurine and glutamate contents are reduced in damaged photoreceptors in dogs with primary glaucoma (PG) in a manner consistent with an ischemia-like release of both of these amino acids from damaged cells." | 3.73 | Depletion of taurine and glutamate from damaged photoreceptors in the retinas of dogs with primary glaucoma. ( Gionfriddo, JR; Madl, JE; McIlnay, TR; Powell, CC, 2005) |
| "Glaucoma is a multifactorial blinding disease with a major inflammatory component ultimately leading to apoptotic retinal ganglion cell (RGC) death." | 1.51 | Protective Efficacy of a Dietary Supplement Based on Forskolin, Homotaurine, Spearmint Extract, and Group B Vitamins in a Mouse Model of Optic Nerve Injury. ( Bagnoli, P; Cammalleri, M; Dal Monte, M; Locri, F; Rusciano, D, 2019) |
| " Similarly, we showed that RGC degeneration can be induced by pharmacologically blocking the taurine-transporter with the chronic administration of a selective inhibitor, which results in a decrease in the taurine levels both in the plasma and in the retinal tissue." | 1.39 | Taurine is a crucial factor to preserve retinal ganglion cell survival. ( Cadetti, L; Degardin, J; Dubus, E; Forster, V; Froger, N; Gaucher, D; Ivkovic, I; Jammoul, F; Lorach, H; Pain, D; Picaud, S; Sahel, JA; Simonutti, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Locri, F | 1 |
| Cammalleri, M | 2 |
| Dal Monte, M | 2 |
| Rusciano, D | 3 |
| Bagnoli, P | 2 |
| Nor Arfuzir, NN | 1 |
| Agarwal, R | 1 |
| Iezhitsa, I | 1 |
| Agarwal, P | 1 |
| Ismail, NM | 1 |
| Amato, R | 1 |
| Adornetto, A | 2 |
| Rombolà, L | 1 |
| Morrone, LA | 2 |
| Nucci, C | 2 |
| Corasaniti, MT | 2 |
| Bagetta, G | 2 |
| Russo, R | 2 |
| Roberti, G | 1 |
| Agnifili, L | 1 |
| Berardo, F | 1 |
| Riva, I | 1 |
| Figus, M | 1 |
| Manni, G | 1 |
| Quaranta, L | 1 |
| Oddone, F | 1 |
| Cavaliere, F | 1 |
| Varano, GP | 1 |
| Froger, N | 1 |
| Jammoul, F | 1 |
| Gaucher, D | 1 |
| Cadetti, L | 1 |
| Lorach, H | 1 |
| Degardin, J | 1 |
| Pain, D | 1 |
| Dubus, E | 1 |
| Forster, V | 1 |
| Ivkovic, I | 1 |
| Simonutti, M | 1 |
| Sahel, JA | 1 |
| Picaud, S | 1 |
| Madl, JE | 1 |
| McIlnay, TR | 1 |
| Powell, CC | 1 |
| Gionfriddo, JR | 1 |
| Olah, Z | 1 |
| Veselovsky, J | 1 |
| Harris, TM | 1 |
| Nance, CS | 1 |
| Sheppard, LB | 1 |
| Fox, RR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Exploring the Effects of a Preservative-free Ophthalmic Solution Containing Hyaluronic Acid 0.4% and Taurine 0.5% on the Ocular Surface of Glaucoma Patients Under Multiple Long-term Topical Hypotensive Therapy[NCT03480295] | 39 participants (Actual) | Interventional | 2016-12-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for taurine and Glaucoma
| Article | Year |
|---|---|
Natural Products: Evidence for Neuroprotection to Be Exploited in Glaucoma.
Topics: Amides; Biological Products; Colforsin; Curcumin; Cytidine Diphosphate Choline; Dietary Supplements; | 2020 |
1 trial available for taurine and Glaucoma
| Article | Year |
|---|---|
Prospective, Randomized, Single Masked, Parallel Study Exploring the Effects of a Preservative-Free Ophthalmic Solution Containing Hyaluronic Acid 0.4% and Taurine 0.5% on the Ocular Surface of Glaucoma Patients Under Multiple Long-Term Topical Hypotensiv
Topics: Aged; Antihypertensive Agents; Dry Eye Syndromes; Female; Glaucoma; Humans; Hyaluronic Acid; Male; M | 2018 |
8 other studies available for taurine and Glaucoma
| Article | Year |
|---|---|
Protective Efficacy of a Dietary Supplement Based on Forskolin, Homotaurine, Spearmint Extract, and Group B Vitamins in a Mouse Model of Optic Nerve Injury.
Topics: Animals; Colforsin; Dietary Supplements; Glaucoma; Mentha spicata; Mice; Optic Nerve Injuries; Plant | 2019 |
Magnesium acetyltaurate protects against endothelin-1 induced RGC loss by reducing neuroinflammation in Sprague dawley rats.
Topics: Animals; Apoptosis; Blotting, Western; Disease Models, Animal; Endothelin-1; Female; Glaucoma; Intra | 2020 |
A Dietary Combination of Forskolin with Homotaurine, Spearmint and B Vitamins Protects Injured Retinal Ganglion Cells in a Rodent Model of Hypertensive Glaucoma.
Topics: Animals; Colforsin; Dietary Supplements; Disease Models, Animal; Female; Glaucoma; Intraocular Press | 2020 |
Intravitreal injection of forskolin, homotaurine, and L-carnosine affords neuroprotection to retinal ganglion cells following retinal ischemic injury.
Topics: Animals; Carnosine; Cell Survival; Colforsin; Disease Models, Animal; Drug Synergism; Glaucoma; Glyc | 2015 |
Taurine is a crucial factor to preserve retinal ganglion cell survival.
Topics: Animals; Cell Survival; Disease Models, Animal; Glaucoma; Membrane Glycoproteins; Membrane Transport | 2013 |
Depletion of taurine and glutamate from damaged photoreceptors in the retinas of dogs with primary glaucoma.
Topics: Animals; Dog Diseases; Dogs; Glaucoma; Glutamic Acid; Photoreceptor Cells; Retina; Taurine | 2005 |
Rabbit's intraocular pressure after instillation of timolol and aminoacid lysine, arginine, glycine or taurine mixture.
Topics: Amino Acids; Animals; Arginine; Drug Combinations; Female; Glaucoma; Glycine; Intraocular Pressure; | 2007 |
Evidence for an hereditary defect in taurine transport in the ciliary epithelium of an inbred strain of rabbits.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Aqueous Humor; Biological Transport; Ciliary Body; Di | 1983 |