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taurine and Encephalopathy, Hepatic

taurine has been researched along with Encephalopathy, Hepatic in 25 studies

Research Excerpts

ExcerptRelevanceReference
"To evaluate the risk of hepatic encephalopathy and arterial hypotension in cirrhotic patients after acute administration of acamprosate, a GABA mimetic drug used in the weaned alcoholic, a randomized double-blind trial was conducted in 24 cirrhotic patients with low or moderate hepatic insufficiency (Pugh grade A or B)."9.07[Effect of acute administration of acamprosate on the risk of encephalopathy and on arterial pressure in patients with alcoholic cirrhosis]. ( Capron, D; Capron, JP; Delgrange, T; Duron, B; Khater, J, 1992)
"This study was to investigate the effects of ammonia and manganese in the metabolism of minimal hepatic encephalopathy (MHE)."8.31The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study. ( Li, Y; Liu, XF; Lu, JJ; Qiang, JW; Yang, XY, 2023)
" The current investigation was designed to evaluate the role of taurine treatment on the brain and liver mitochondrial function in a rat model of hepatic encephalopathy and hyperammonemia."7.85Taurine treatment preserves brain and liver mitochondrial function in a rat model of fulminant hepatic failure and hyperammonemia. ( Abasvali, M; Abdoli, N; Asadi, B; Azarpira, N; Heidari, R; Jafari, F; Jamshidzadeh, A; Khodaei, F; Latifpour, Z; Mardani, E; Najibi, A; Ommati, MM; Yeganeh, Y; Zarei, A; Zarei, M, 2017)
"The possible involvement of taurine in the pathogenesis of hepatic encephalopathy was studied in rats injected with thioacetamide."7.68Taurine release from brain slices in thioacetamide-induced hepatic encephalopathy in rats. ( Oja, SS; Saransaari, P; Wysmyk, U, 1991)
"By contrast, rats with hepatic encephalopathy (HE) following administration of a hepatotoxin, thioacetamide, were characterized by CC edema and an increased Tau content in both BG and CC."5.29Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure. ( Albrecht, J; Hilgier, W; Olson, JE, 1996)
"To evaluate the risk of hepatic encephalopathy and arterial hypotension in cirrhotic patients after acute administration of acamprosate, a GABA mimetic drug used in the weaned alcoholic, a randomized double-blind trial was conducted in 24 cirrhotic patients with low or moderate hepatic insufficiency (Pugh grade A or B)."5.07[Effect of acute administration of acamprosate on the risk of encephalopathy and on arterial pressure in patients with alcoholic cirrhosis]. ( Capron, D; Capron, JP; Delgrange, T; Duron, B; Khater, J, 1992)
"This study was to investigate the effects of ammonia and manganese in the metabolism of minimal hepatic encephalopathy (MHE)."4.31The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study. ( Li, Y; Liu, XF; Lu, JJ; Qiang, JW; Yang, XY, 2023)
" The current investigation was designed to evaluate the role of taurine treatment on the brain and liver mitochondrial function in a rat model of hepatic encephalopathy and hyperammonemia."3.85Taurine treatment preserves brain and liver mitochondrial function in a rat model of fulminant hepatic failure and hyperammonemia. ( Abasvali, M; Abdoli, N; Asadi, B; Azarpira, N; Heidari, R; Jafari, F; Jamshidzadeh, A; Khodaei, F; Latifpour, Z; Mardani, E; Najibi, A; Ommati, MM; Yeganeh, Y; Zarei, A; Zarei, M, 2017)
" decreases by 25% the high (50 mM) K+-evoked accumulation of Tau in striatal microdialysates of healthy rats and by 34% in rats with thioacetamide-induced hepatic failure, where the increased extracellular accumulation of Tau signifies ongoing hepatic encephalopathy."3.71Lubeluzole attenuates K(+)-evoked extracellular accumulation of taurine in the striatum of healthy rats and rats with hepatic failure. ( Albrecht, J; Borkowska, HD; Hilgier, W; Oja, SS; Saransaari, P; Zielińska, M, 2001)
"Rats were treated with a hepatotoxin thioacetamide (TAA) and examined 21 days later, when they showed moderate fatty metamorphosis of the liver and morphological changes in brain indicative of excitotoxic neuronal damage, but no evident biochemical or neurophysiological symptoms of hepatic encephalopathy (HE)."3.70Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure. ( Albrecht, J; Borkowska, HD; Gadamski, R; Hilgier, W; Oja, SS; Saransaari, P; Walski, M; Zielińska, M, 1999)
"The possible involvement of taurine in the pathogenesis of hepatic encephalopathy was studied in rats injected with thioacetamide."3.68Taurine release from brain slices in thioacetamide-induced hepatic encephalopathy in rats. ( Oja, SS; Saransaari, P; Wysmyk, U, 1991)
"Taurine (Tau) is an amino acid that is thought to mimic GABA function because of its agonistic properties towards GABA(A) receptors, and to contribute to neuroprotection and osmoregulation."2.41The role of inhibitory amino acidergic neurotransmission in hepatic encephalopathy: a critical overview. ( Albrecht, J; Zielińska, M, 2002)
"Myo-inositol levels were strongly decreased already at 3h after treatment with NH4Cl; other intracellular osmolytes, such as hypotaurine and choline-containing compounds were also decreased, along with a concomitant increase of both the total concentration and the amount of newly synthesized glutamine, alanine, and glutathione."1.33Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response. ( Leibfritz, D; Zwingmann, C, 2005)
"By contrast, rats with hepatic encephalopathy (HE) following administration of a hepatotoxin, thioacetamide, were characterized by CC edema and an increased Tau content in both BG and CC."1.29Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure. ( Albrecht, J; Hilgier, W; Olson, JE, 1996)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.00)18.7374
1990's8 (32.00)18.2507
2000's7 (28.00)29.6817
2010's4 (16.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Claeys, W1
Van Hoecke, L1
Geerts, A1
Van Vlierberghe, H1
Lefere, S1
Van Imschoot, G1
Van Wonterghem, E1
Ghesquière, B1
Vandenbroucke, RE1
Van Steenkiste, C1
Liu, XF1
Lu, JJ1
Li, Y1
Yang, XY1
Qiang, JW1
Schnelle, ANW1
Richardson, LT1
Pettit, ME1
DeMorrow, S1
Solouki, T1
Ahmadi, N1
Ghanbarinejad, V1
Ommati, MM2
Jamshidzadeh, A2
Heidari, R3
Abasvali, M1
Zarei, M1
Abdoli, N1
Khodaei, F1
Yeganeh, Y1
Jafari, F1
Zarei, A1
Latifpour, Z1
Mardani, E1
Azarpira, N1
Asadi, B1
Najibi, A1
Singhal, A1
Nagarajan, R1
Kumar, R1
Huda, A1
Gupta, RK1
Thomas, MA1
Bodega, G1
Suárez, I1
López-Fernández, LA1
García, MI1
Köber, M1
Penedo, M1
Luna, M1
Juárez, S1
Ciordia, S1
Oria, M1
Córdoba, J1
Fernández, B1
Albrecht, J5
Zielińska, M4
Zwingmann, C2
Chatauret, N1
Rose, C1
Leibfritz, D2
Butterworth, RF3
Chepkova, AN1
Sergeeva, OA1
Haas, HL1
Rao, VL1
Audet, RM1
Hilgier, W4
Olson, JE1
Morsiani, E1
Pazzi, P1
Moscioni, AD1
Rozga, J1
Azzena, G1
Demetriou, AA1
Borkowska, HD2
Gadamski, R1
Walski, M1
Oja, SS3
Saransaari, P3
Law, RO1
Smith, AR1
Rossi-Fanelli, F1
Freund, H1
Fischer, JE1
Delgrange, T1
Khater, J1
Capron, D1
Duron, B1
Capron, JP1
Wysmyk, U1
Maddison, JE1
Leong, DK1
Dodd, PR1
Johnston, GA1
Benjamin, LE1
Steele, RD1
Verzetti, G1
Emanuelli, G1
Montagnani, M1

Reviews

3 reviews available for taurine and Encephalopathy, Hepatic

ArticleYear
Brain mitochondria as potential therapeutic targets for managing hepatic encephalopathy.
    Life sciences, 2019, Feb-01, Volume: 218

    Topics: Animals; Brain; Brain Injuries; Energy Metabolism; Hepatic Encephalopathy; Humans; Hyperammonemia; M

2019
The role of inhibitory amino acidergic neurotransmission in hepatic encephalopathy: a critical overview.
    Metabolic brain disease, 2002, Volume: 17, Issue:4

    Topics: Amino Acids; Animals; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Models, Neurological; Neural

2002
Taurine in hepatic encephalopathy.
    Advances in experimental medicine and biology, 1996, Volume: 403

    Topics: Animals; Biomarkers; Brain; Brain Edema; Hepatic Encephalopathy; Humans; Intracranial Pressure; Live

1996

Trials

1 trial available for taurine and Encephalopathy, Hepatic

ArticleYear
[Effect of acute administration of acamprosate on the risk of encephalopathy and on arterial pressure in patients with alcoholic cirrhosis].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:8-9

    Topics: Acamprosate; Administration, Oral; Adult; Blood Pressure; Double-Blind Method; Drug Evaluation; Evok

1992

Other Studies

21 other studies available for taurine and Encephalopathy, Hepatic

ArticleYear
A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.
    Scientific reports, 2022, 10-20, Volume: 12, Issue:1

    Topics: Ammonia; Animals; Bile Acids and Salts; Bile Ducts; Brain; Choline; Disease Models, Animal; Glutamin

2022
The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Alanine; Ammonia; Animals; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glut

2023
Trihydroxycholanoyl-taurine in brains of rodents with hepatic encephalopathy.
    Journal of mass spectrometry : JMS, 2021, Volume: 56, Issue:6

    Topics: Animals; Bile Acids and Salts; Chromatography, High Pressure Liquid; Hepatic Encephalopathy; Isomeri

2021
Taurine prevents mitochondrial membrane permeabilization and swelling upon interaction with manganese: Implication in the treatment of cirrhosis-associated central nervous system complications.
    Journal of biochemical and molecular toxicology, 2018, Volume: 32, Issue:11

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Brain; Hepatic Encephalopathy; Kinetics; Male; Mangan

2018
Taurine treatment preserves brain and liver mitochondrial function in a rat model of fulminant hepatic failure and hyperammonemia.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 86

    Topics: Adenosine Triphosphate; Ammonia; Animals; Brain; Hepatic Encephalopathy; Hyperammonemia; Liver; Live

2017
Magnetic resonance T2-relaxometry and 2D L-correlated spectroscopy in patients with minimal hepatic encephalopathy.
    Journal of magnetic resonance imaging : JMRI, 2009, Volume: 30, Issue:5

    Topics: Adult; Aged; Brain; Choline; Creatine; Female; Hepatic Encephalopathy; Humans; Inositol; Liver; Magn

2009
Ammonia induces aquaporin-4 rearrangement in the plasma membrane of cultured astrocytes.
    Neurochemistry international, 2012, Volume: 61, Issue:8

    Topics: alpha-Synuclein; Ammonia; Animals; Aquaporin 4; Astrocytes; Brain Edema; Cell Membrane; Cells, Cultu

2012
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia.
    Brain research, 2004, Feb-27, Volume: 999, Issue:1

    Topics: Animals; Brain Edema; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Hypothermia, Induce

2004
Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response.
    Neurochemistry international, 2005, Volume: 47, Issue:1-2

    Topics: Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Animals, Newborn; Astrocytes; Brain Edema

2005
Taurine rescues hippocampal long-term potentiation from ammonia-induced impairment.
    Neurobiology of disease, 2006, Volume: 23, Issue:3

    Topics: Ammonium Chloride; Animals; Carnitine; Energy Metabolism; Hepatic Encephalopathy; Hippocampus; Hyper

2006
Selective alterations of extracellular brain amino acids in relation to function in experimental portal-systemic encephalopathy: results of an in vivo microdialysis study.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: Acetates; Alanine; Amino Acids; Animals; Brain; Dialysis; Extracellular Space; Frontal Lobe; Glutami

1995
Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure.
    Journal of neuroscience research, 1996, Jul-01, Volume: 45, Issue:1

    Topics: Ammonia; Animals; Basal Ganglia; Body Water; Brain Edema; Cerebral Cortex; Hepatic Encephalopathy; I

1996
In vitro morphological and functional characterization of isolated porcine hepatocytes for extracorporeal liver support: bile acid uptake and conjugation.
    The Journal of surgical research, 1998, Volume: 79, Issue:1

    Topics: Animals; Bile Acids and Salts; Cells, Cultured; Female; Glycine; Hepatic Encephalopathy; Humans; Liv

1998
Changes in the extracellular profiles of neuroactive amino acids in the rat striatum at the asymptomatic stage of hepatic failure.
    Journal of neuroscience research, 1999, Apr-01, Volume: 56, Issue:1

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Biological Transport; Corpus Striatum; Excitatory Amin

1999
Lubeluzole attenuates K(+)-evoked extracellular accumulation of taurine in the striatum of healthy rats and rats with hepatic failure.
    Brain research, 2001, Jun-15, Volume: 904, Issue:1

    Topics: Animals; Extracellular Space; Glutamic Acid; Hepatic Encephalopathy; Male; Microdialysis; Neostriatu

2001
Taurine, glutamine, glutamate, and aspartate content and efflux, and cell volume of cerebrocortical minislices of rats with hepatic encephalopathy: influence of ammonia.
    Advances in experimental medicine and biology, 2000, Volume: 483

    Topics: Ammonia; Animals; Aspartic Acid; Cell Size; Cerebral Cortex; Glutamic Acid; Glutamine; Hepatic Encep

2000
Sulfur-containing amino acids in experimental hepatic coma in the dog and the monkey.
    Surgery, 1979, Volume: 85, Issue:6

    Topics: Amino Acids, Branched-Chain; Amino Acids, Sulfur; Animals; Brain Chemistry; Disease Models, Animal;

1979
Taurine release from brain slices in thioacetamide-induced hepatic encephalopathy in rats.
    Molecular and chemical neuropathology, 1991, Volume: 14, Issue:1

    Topics: Ammonia; Ammonium Chloride; Animals; Brain Chemistry; Corpus Striatum; Hepatic Encephalopathy; Male;

1991
Plasma GABA-like activity in rats with hepatic encephalopathy is due to GABA and taurine.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:1

    Topics: Animals; Binding, Competitive; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutam

1990
The effect of dietary protein on nitrogen and sulfur metabolism in portacaval-shunted rats.
    The Journal of nutrition, 1986, Volume: 116, Issue:1

    Topics: Amino Acids, Sulfur; Ammonia; Animals; Body Weight; Dietary Proteins; Hepatic Encephalopathy; Liver;

1986
[Therapy of hyperammonemia: effect of a preparation arginine pyrrolidonecarboxylate, taurine, vitamin B6 and citric acid].
    La Clinica terapeutica, 1972, Mar-15, Volume: 60, Issue:5

    Topics: Amino Acids; Ammonia; Arginine; Brain Diseases; Citrates; Drug Combinations; Hepatic Encephalopathy;

1972