Page last updated: 2024-10-20

taurine and Drug Withdrawal Symptoms

taurine has been researched along with Drug Withdrawal Symptoms in 55 studies

Research Excerpts

ExcerptRelevanceReference
"Chronic amphetamine use results in anxiety-like states after drug cessation."7.79The influence of ionotropic and metabotropic glutamate receptor ligands on anxiety-like effect of amphetamine withdrawal in rats. ( Gibula-Bruzda, E; Koltunowska, D; Kotlinska, JH, 2013)
"Acamprosate was discontinued in nine patients (1%) because of severe adverse events; only two cases were clearly linked to treatment (diarrhoea and dermatitis)."6.70Use of acamprosate and different kinds of psychosocial support in relapse prevention of alcoholism. Results from a non-blind, multicentre study. ( Preuss, U; Schuetz, C; Soyka, M, 2002)
"Chronic amphetamine use results in anxiety-like states after drug cessation."3.79The influence of ionotropic and metabotropic glutamate receptor ligands on anxiety-like effect of amphetamine withdrawal in rats. ( Gibula-Bruzda, E; Koltunowska, D; Kotlinska, JH, 2013)
" The effect of neramexane, a low-to-moderate affinity uncompetitive NMDA receptor antagonist, was examined on the development and expression of ethanol dependence (withdrawal-associated audiogenic seizures) and ethanol-induced conditioned place preference."3.72Effect of neramexane on ethanol dependence and reinforcement. ( Biala, G; Bochenski, M; Danysz, W; Kotlinska, J; Rafalski, P, 2004)
"Acamprosate was well tolerated during the entire course of the study."2.72Effects of acamprosate on sleep during alcohol withdrawal: A double-blind placebo-controlled polysomnographic study in alcohol-dependent subjects. ( Boeijinga, P; Danel, T; Gendre, I; Landron, F; Luthringer, R; Muzet, M; Staner, L, 2006)
"Acamprosate was discontinued in nine patients (1%) because of severe adverse events; only two cases were clearly linked to treatment (diarrhoea and dermatitis)."2.70Use of acamprosate and different kinds of psychosocial support in relapse prevention of alcoholism. Results from a non-blind, multicentre study. ( Preuss, U; Schuetz, C; Soyka, M, 2002)
"Prevalence of alcohol dependence remains stable across time between 5-7% in men and 2-3% in women, corresponding to at least 1."2.44[Alcohol dependence: diagnosis and treatment]. ( Blanc, F; Perney, P; Rigole, H, 2008)
"Acamprosate is a proven effective intervention in the treatment of alcohol dependence."2.43Predictors of acamprosate efficacy: results from a pooled analysis of seven European trials including 1485 alcohol-dependent patients. ( Geerlings, PJ; Koeter, MW; Lehert, P; van den Brink, W; Verheul, R, 2005)
"Acamprosate was generally well tolerated in placebo-controlled trials."2.40Acamprosate. A review of its pharmacology and clinical potential in the management of alcohol dependence after detoxification. ( Wagstaff, AJ; Wilde, MI, 1997)
"Antalarmin did not produce a place preference or place aversion by itself in morphine-dependent rats."1.33Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats. ( Cador, M; Koob, GF; Stinus, L; Zorrilla, EP, 2005)
" According to these observations, NR2B SSNAs are potent inhibitors of ethanol-withdrawal-induced neurotoxicity and considering that these agents have acceptable side effect profiles, they could be promising therapeutic candidates in the pharmacotherapy for physical signs of acute alcohol-withdrawal and associated neuronal damage."1.32NR2B subunit selective NMDA antagonists inhibit neurotoxic effect of alcohol-withdrawal in primary cultures of rat cortical neurones. ( Farkas, S; Horváth, C; Kolok, S; Nagy, J; Szombathelyi, Z, 2004)
" Chronic administration of lower daily doses of acamprosate (100 and 200 mg/kg) blocked the increased ethanol consumption typically observed in rats after an imposed abstinence period."1.30Chronic acamprosate eliminates the alcohol deprivation effect while having limited effects on baseline responding for ethanol in rats. ( Durbin, P; Heyser, CJ; Koob, GF; Schulteis, G, 1998)
"Sleep-wake states were studied following withdrawal in 36 adult male wistar alcohol-dependent rats, after chronic administration of ethanol (10 g/kg/24 h) for 13 days."1.30Effects of muscimol or homotaurine on sleep-wake states in alcohol-dependent rats during withdrawal. ( Bajenaru, O; Dall'Ava-Santucci, J; Dinh-Xuan, AT; Emmanouilidis, E; Manicom, R; Poenaru, S; Rouhani, S; Tran, G, 1998)
"When acamprosate was given to alcohol-naive animals, it increased locomotor activity and body temperature transiently, in particular during the rats' active night phase."1.29Acamprosate and alcohol: II. Effects on alcohol withdrawal in the rat. ( Putzke, J; Schöbitz, B; Spanagel, R; Stefferl, A; Zieglgänsberger, W, 1996)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19905 (9.09)18.7374
1990's13 (23.64)18.2507
2000's27 (49.09)29.6817
2010's10 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koltunowska, D1
Gibula-Bruzda, E1
Kotlinska, JH1
Müller, CA1
Heinz, A1
Higuchi, S2
Mason, BJ2
Ponizovskiy, PA1
Gofman, AG1
Yumoto, Y1
Stoddard, J1
Zummo, J1
Soyka, M2
Kotlinska, J2
Bochenski, M2
Hinton, DJ1
Lee, MR1
Jacobson, TL1
Mishra, PK1
Frye, MA1
Mrazek, DA1
Macura, SI1
Choi, DS1
Clark, DB1
Kalk, NJ1
Lingford-Hughes, AR1
Mayer, S1
Harris, BR1
Gibson, DA1
Blanchard, JA1
Prendergast, MA1
Holley, RC1
Littleton, J2
Dahchour, A4
De Witte, P6
Nagy, J1
Horváth, C1
Farkas, S1
Kolok, S1
Szombathelyi, Z1
Smolka, MN2
Kiefer, F2
Mann, K3
Stinus, L1
Cador, M1
Zorrilla, EP1
Koob, GF4
Boeijinga, PH1
Parot, P1
Soufflet, L1
Landron, F2
Danel, T2
Gendre, I2
Muzet, M2
Demazières, A1
Luthringer, R2
Zakharova, E1
Malyshkin, A1
Kashkin, V1
Neznanova, O1
Sukhotina, I1
Danysz, W2
Bespalov, A1
Verheul, R1
Lehert, P1
Geerlings, PJ1
Koeter, MW1
van den Brink, W1
Biala, G1
Rafalski, P1
Lallemand, F1
Ward, RJ1
Staner, L1
Boeijinga, P1
Füllgrabe, MW1
Vengeliene, V1
Spanagel, R6
Diehl, A1
Perney, P1
Rigole, H1
Blanc, F1
Contreras, E1
Tamayo, L1
Iwata, H1
Matsuda, T1
Lee, E1
Yamagami, S1
Baba, A1
Jhamandas, KH1
Marsala, M1
Ibuki, T1
Yaksh, TL1
Putzke, J2
Stefferl, A1
Schöbitz, B1
Zieglgänsberger, W4
Tölle, TR1
Wilde, MI1
Wagstaff, AJ1
Hölter, SM2
Landgraf, R1
Heyser, CJ1
Schulteis, G1
Durbin, P2
Rouhani, S1
Dall'Ava-Santucci, J1
Bajenaru, O1
Emmanouilidis, E1
Tran, G2
Manicom, R1
Dinh-Xuan, AT1
Poenaru, S1
Kratzer, U1
Schmidt, WJ1
Cole, JC1
Littleton, JM1
Little, HJ1
Myrick, H1
Brady, KT1
Malcolm, R1
Korpi, E1
Seppälä, T1
Preuss, U1
Schuetz, C1
Siggins, GR1
Ikeda, H1
Gewiss, M1
Heidbreder, C1
Opsomer, L1
Lhuintre, JP1
Daoust, M1
Moore, ND1
Chretien, P1
Saligaut, C1
Bosimare, F1
Hillemand, B1
Liskow, BI1
Goodwin, DW1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Augment in Treatment-resistent Obsessive-compulsive Disorder: an Open-label Trial[NCT00590642]30 participants (Anticipated)Observational2006-04-30Completed
Acamprosate for Central Nervous System Hyperexcitability and Neuroadaptation in Alcohol Withdrawal[NCT00106106]Phase 256 participants (Actual)Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Ratio of Glutamate to Creatine in the Anterior Cingulate of the Brain, Measured on Day 25

The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 25

InterventionRatio of glutamate to creatine (Mean)
Placebo1.350375
Acamprosate1.166667

Ratio of Glutamate to Creatine in the Anterior Cingulate of the Brain, Measured on Day 4

The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 4

InterventionRatio of glutamate to creatine (Mean)
Placebo1.256772
Acamprosate1.294178

Reviews

16 reviews available for taurine and Drug Withdrawal Symptoms

ArticleYear
[New treatment options for alcohol dependence].
    MMW Fortschritte der Medizin, 2013, May-02, Volume: 155, Issue:8

    Topics: Acamprosate; Alcoholism; Baclofen; Combined Modality Therapy; Ethanol; Fructose; Humans; Naltrexone;

2013
[Depression in alcohol addicted patients].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:7

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Antidepressive Agents; Comorbidity; Depressive Disorder

2015
[Pharmacological therapies for alcohol use disorder in Japan].
    Nihon rinsho. Japanese journal of clinical medicine, 2015, Volume: 73, Issue:9

    Topics: Acamprosate; Alcohol-Related Disorders; Alcohols; Humans; Japan; Naltrexone; Substance Withdrawal Sy

2015
The clinical pharmacology of acamprosate.
    British journal of clinical pharmacology, 2014, Volume: 77, Issue:2

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Humans; Rodentia; Secondary Prevention; Substa

2014
Predictors of acamprosate efficacy: results from a pooled analysis of seven European trials including 1485 alcohol-dependent patients.
    Psychopharmacology, 2005, Volume: 178, Issue:2-3

    Topics: Acamprosate; Adult; Age Factors; Aged; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Anxiety; Do

2005
[Advances in the treatment of alcohol dependence: pharmacological relapse prevention].
    MMW Fortschritte der Medizin, 2003, Oct-09, Volume: 145 Suppl 3

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Ethanol; Humans; Randomized Controlled Trials as Topic;

2003
[Pharmacological relapse prevention in alcohol and tobacco dependence].
    Der Internist, 2007, Volume: 48, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Clinical Trials as Topic; Combined Modality Therapy; Di

2007
[Alcohol dependence: diagnosis and treatment].
    La Revue de medecine interne, 2008, Volume: 29, Issue:4

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Cognitive Behavioral Therapy; Disulfiram; Humans; Motiv

2008
Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes.
    Trends in pharmacological sciences, 1997, Volume: 18, Issue:2

    Topics: Acamprosate; Alcoholism; Animals; Behavior, Animal; Calcium Channels; Disease Models, Animal; Humans

1997
Acamprosate. A review of its pharmacology and clinical potential in the management of alcohol dependence after detoxification.
    Drugs, 1997, Volume: 53, Issue:6

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Clinical Trials as Topic; Drug Evaluation, Pre

1997
Acamprosate for alcohol dependence?
    Drug and therapeutics bulletin, 1997, Volume: 35, Issue:9

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Controlled Clinical Trials as Topic; Humans; Substance

1997
Animal models of craving for ethanol.
    Addiction (Abingdon, England), 2000, Volume: 95 Suppl 2

    Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Animals; Behavior, Addictive; Conditioning, Opera

2000
New developments in the pharmacotherapy of alcohol dependence.
    The American journal on addictions, 2001, Volume: 10, Issue:s1

    Topics: Acamprosate; Adjuvants, Anesthesia; Alcohol Deterrents; Alcoholism; Anticonvulsants; Buspirone; Carb

2001
[Alcohol--mechanism of action, interactions and treatment of alcohol abuse].
    Duodecim; laaketieteellinen aikakauskirja, 1998, Volume: 114, Issue:10

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Drug Interactions; Ethanol; Humans; Naltrexone; Narcoti

1998
Acamprosate.
    Drugs in R&D, 2002, Volume: 3, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Drug Interactions; Humans; Substance Withdrawal Syndrom

2002
Pharmacological treatment of alcohol intoxication, withdrawal and dependence: a critical review.
    Journal of studies on alcohol, 1987, Volume: 48, Issue:4

    Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Antidepressive Agents, Tricyclic; Bromocript

1987

Trials

5 trials available for taurine and Drug Withdrawal Symptoms

ArticleYear
Efficacy of acamprosate for the treatment of alcohol dependence long after recovery from withdrawal syndrome: a randomized, double-blind, placebo-controlled study conducted in Japan (Sunrise Study).
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:2

    Topics: Acamprosate; Adult; Aged; Alcoholism; Double-Blind Method; Ethanol; Female; Humans; Japan; Long-Term

2015
Pharmacodynamic effects of acamprosate on markers of cerebral function in alcohol-dependent subjects administered as pretreatment and during alcohol abstinence.
    Neuropsychobiology, 2004, Volume: 50, Issue:1

    Topics: Acamprosate; Adult; Alcohol Deterrents; Alcoholism; Arousal; Cerebral Cortex; Double-Blind Method; E

2004
Effects of acamprosate on sleep during alcohol withdrawal: A double-blind placebo-controlled polysomnographic study in alcohol-dependent subjects.
    Alcoholism, clinical and experimental research, 2006, Volume: 30, Issue:9

    Topics: Acamprosate; Adult; Alcohol Deterrents; Alcoholism; Central Nervous System Depressants; Compulsive P

2006
Use of acamprosate and different kinds of psychosocial support in relapse prevention of alcoholism. Results from a non-blind, multicentre study.
    Drugs in R&D, 2002, Volume: 3, Issue:1

    Topics: Acamprosate; Adolescent; Adult; Aged; Alcohol Deterrents; Alcoholism; Double-Blind Method; Female; G

2002
Ability of calcium bis acetyl homotaurine, a GABA agonist, to prevent relapse in weaned alcoholics.
    Lancet (London, England), 1985, May-04, Volume: 1, Issue:8436

    Topics: Acamprosate; Adult; Alcoholism; Clinical Trials as Topic; Double-Blind Method; Erythrocyte Indices;

1985

Other Studies

34 other studies available for taurine and Drug Withdrawal Symptoms

ArticleYear
The influence of ionotropic and metabotropic glutamate receptor ligands on anxiety-like effect of amphetamine withdrawal in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Aug-01, Volume: 45

    Topics: Acamprosate; Amphetamine; Animals; Anxiety; Bridged Bicyclo Compounds; Dose-Response Relationship, D

2013
Acamprosate, alcoholism, and abstinence.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:2

    Topics: Alcoholism; Ethanol; Female; Humans; Male; Substance Withdrawal Syndrome; Taurine

2015
Oral and long-acting injectable naltrexone: removal of boxed warning for hepatotoxicity.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:12

    Topics: Alcoholism; Ethanol; Female; Humans; Male; Substance Withdrawal Syndrome; Taurine

2015
[Pharmacotherapy of alcohol dependence].
    MMW Fortschritte der Medizin, 2008, May-19, Volume: 150 Suppl 2

    Topics: Acamprosate; Adrenergic beta-Antagonists; Alcohol Deterrents; Alcoholism; Ambulatory Care; Anticonvu

2008
The influence of various glutamate receptors antagonists on anxiety-like effect of ethanol withdrawal in a plus-maze test in rats.
    European journal of pharmacology, 2008, Nov-19, Volume: 598, Issue:1-3

    Topics: Acamprosate; Alcohol Deterrents; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressa

2008
Ethanol withdrawal-induced brain metabolites and the pharmacological effects of acamprosate in mice lacking ENT1.
    Neuropharmacology, 2012, Volume: 62, Issue:8

    Topics: Acamprosate; Animals; Brain; Equilibrative Nucleoside Transporter 1; Ethanol; gamma-Aminobutyric Aci

2012
Pharmacotherapy for adolescent alcohol use disorder.
    CNS drugs, 2012, Jul-01, Volume: 26, Issue:7

    Topics: Acamprosate; Adolescent; Alcohol-Related Disorders; Antidepressive Agents; Attention Deficit Disorde

2012
Acamprosate, MK-801, and ifenprodil inhibit neurotoxicity and calcium entry induced by ethanol withdrawal in organotypic slice cultures from neonatal rat hippocampus.
    Alcoholism, clinical and experimental research, 2002, Volume: 26, Issue:10

    Topics: Acamprosate; Animals; Animals, Newborn; Calcium Signaling; Dizocilpine Maleate; Ethanol; Female; Hip

2002
Effects of acamprosate on excitatory amino acids during multiple ethanol withdrawal periods.
    Alcoholism, clinical and experimental research, 2003, Volume: 27, Issue:3

    Topics: Acamprosate; Animals; Ethanol; Excitatory Amino Acids; Hippocampus; Male; Rats; Rats, Wistar; Substa

2003
NR2B subunit selective NMDA antagonists inhibit neurotoxic effect of alcohol-withdrawal in primary cultures of rat cortical neurones.
    Neurochemistry international, 2004, Volume: 44, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Clone Cells; Cy

2004
[Psychosocial treatment plus drug prophylaxis. Fewer recurrences after alcohol withdrawal].
    MMW Fortschritte der Medizin, 2003, Sep-04, Volume: 145, Issue:35-36

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Combined Modality Therapy; Ethanol; Humans; Randomized

2003
Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:1

    Topics: Acamprosate; Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Avoidance Learni

2005
The NMDA receptor channel blocker memantine and opioid receptor antagonist naltrexone inhibit the saccharin deprivation effect in rats.
    Behavioural pharmacology, 2004, Volume: 15, Issue:4

    Topics: Acamprosate; Animals; Choice Behavior; Ethanol; Male; Memantine; Naloxone; Naltrexone; Narcotic Anta

2004
Effect of neramexane on ethanol dependence and reinforcement.
    European journal of pharmacology, 2004, Oct-25, Volume: 503, Issue:1-3

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Behavior, Animal; Central Nervous System Depre

2004
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats.
    European journal of pharmacology, 2005, Sep-27, Volume: 520, Issue:1-3

    Topics: Acamprosate; Acetaldehyde; Alcohol Deterrents; Alcoholism; Animals; Disease Models, Animal; Ethanol;

2005
Drug treatment for alcoholism today.
    The Harvard mental health letter, 2005, Volume: 22, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Antidepressive Agents; Disulfiram; Fructose; Humans; Na

2005
Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:2

    Topics: Acamprosate; Age of Onset; Aging; Alcohol Deterrents; Alcohol Drinking; Animals; Central Nervous Sys

2007
Effects of taurine on tolerance to and dependence on morphine in mice.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 267, Issue:2

    Topics: Analgesia; Animals; Behavior, Animal; Drug Tolerance; Female; Humans; Mice; Morphine; Morphine Depen

1984
Effect of ethanol on taurine concentration in the brain.
    Experientia, 1980, Mar-15, Volume: 36, Issue:3

    Topics: Alcoholism; Animals; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Ethanol; Humans; Male; Rats; Sl

1980
Spinal amino acid release and precipitated withdrawal in rats chronically infused with spinal morphine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Apr-15, Volume: 16, Issue:8

    Topics: Amino Acids; Animals; Clonidine; Dizocilpine Maleate; Glutamic Acid; Glycine; Injections, Spinal; Ma

1996
Acamprosate and alcohol: II. Effects on alcohol withdrawal in the rat.
    European journal of pharmacology, 1996, Jun-03, Volume: 305, Issue:1-3

    Topics: Acamprosate; Alcohol Deterrents; Animals; Body Temperature; Drinking; Eating; Ethanol; Male; Motor A

1996
The anti-craving drug acamprosate reduces c-fos expression in rats undergoing ethanol withdrawal.
    European journal of pharmacology, 1996, Dec-12, Volume: 317, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Animals; Central Nervous System Depressants; Cerebellum; Convulsant

1996
Time course of acamprosate action on operant ethanol self-administration after ethanol deprivation.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:5

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Conditioning, Operant; Dose-Response Relations

1997
Chronic acamprosate eliminates the alcohol deprivation effect while having limited effects on baseline responding for ethanol in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 18, Issue:2

    Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Animals; Central Nervous System Depressants; Cond

1998
Effects of muscimol or homotaurine on sleep-wake states in alcohol-dependent rats during withdrawal.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:4

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Behavior, Animal; Body Weight; Central Nervous System D

1998
The anti-craving drug acamprosate inhibits the conditioned place aversion induced by naloxone-precipitated morphine withdrawal in rats.
    Neuroscience letters, 1998, Aug-07, Volume: 252, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Analgesics, Opioid; Animals; Conditioning, Psychological; Drug Inte

1998
Acamprosate decreases the hypermotility during repeated ethanol withdrawal.
    Alcohol (Fayetteville, N.Y.), 1999, Volume: 18, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Animals; Central Nervous System Depressants; Ethanol; Glutamic Acid

1999
Acamprosate, but not naltrexone, inhibits conditioned abstinence behaviour associated with repeated ethanol administration and exposure to a plus-maze.
    Psychopharmacology, 2000, Volume: 147, Issue:4

    Topics: Acamprosate; Alcohol Deterrents; Animals; Anxiety; Central Nervous System Depressants; Ethanol; Expl

2000
Taurine blocks the glutamate increase in the nucleus accumbens microdialysate of ethanol-dependent rats.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:2

    Topics: Alcoholism; Animals; Arginine; Central Nervous System Depressants; Ethanol; gamma-Aminobutyric Acid;

2000
Pharmacological validation of a new animal model of alcoholism.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:6

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Behavior, Animal; Disease Models, Animal; Nalt

2000
Drug treatments for alcoholism.
    The Harvard mental health letter, 2002, Volume: 18, Issue:10

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Disulfiram; Humans; Naltrexone; Substance Withdrawal Sy

2002
Potential neuroprotective effects of acamprosate.
    Alcoholism, clinical and experimental research, 2002, Volume: 26, Issue:4

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Brain; Humans; Neuroprotective Agents; Substan

2002
Effects of taurine on alcohol withdrawal.
    Lancet (London, England), 1977, Sep-03, Volume: 2, Issue:8036

    Topics: Alcoholism; Chronic Disease; Ethanol; Humans; Substance Withdrawal Syndrome; Taurine

1977
Acamprosate and diazepam differentially modulate alcohol-induced behavioural and cortical alterations in rats following chronic inhalation of ethanol vapour.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1991, Volume: 26, Issue:2

    Topics: Acamprosate; Administration, Inhalation; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Anima

1991