taurine has been researched along with Disease Exacerbation in 33 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and tolerability of taurolidine, an antibacterial substance, was evaluated in a phase 2 trial enrolling patients with advanced melanoma." | 9.15 | The antibacterial substance, taurolidine in the second/third-line treatment of very advanced stage IV melanoma including brain metastases: results of a phase 2, open-label study. ( Baumann, K; Dummer, R; French, LE; Goldinger, SM; Imhof, L; Röthlisberger, P; Schad, K, 2011) |
| "The purpose of this study to assess the effect of the formula taurine/diltiazem/vitamin E on the progression of visual field loss in retinitis pigmentosa." | 9.10 | Treatment with taurine, diltiazem, and vitamin E retards the progressive visual field reduction in retinitis pigmentosa: a 3-year follow-up study. ( Pasantes-Morales, H; Quesada, O; Quiroz, H, 2002) |
| "Topical liposomal MgT delays cataractogenesis in galactose-fed rats by maintaining the lens mineral homeostasis and reducing lenticular oxidative and nitrosative stress." | 7.83 | Mechanism of the anticataract effect of liposomal MgT in galactose-fed rats. ( Agarwal, P; Agarwal, R; Alyautdin, R; Iezhitsa, I; Ismail, NM; Krasilnikova, A; Ozerov, A; Rahman, TH; Rozali, KN; Saad, SD; Spasov, A; Zakaria, FK, 2016) |
| "Taurine has also been shown to reduce lenticular oxidative stress." | 5.39 | Effects of magnesium taurate on the onset and progression of galactose-induced experimental cataract: in vivo and in vitro evaluation. ( Abdul Rahman, TH; Agarwal, P; Agarwal, R; Ahmad Fisol, NF; Awaludin, NA; Bakar, NS; Iezhitsa, I; Mohamed Ahmed Salama, MS; Mohd Ismail, N; Ozerov, A; Spasov, A, 2013) |
| "Re-expansion pulmonary edema (RPE) is an acute, rare and potentially lethal complication." | 5.35 | Protective efficiacy of taurine against pulmonary edema progression: experimental study. ( Genc, O; Gozubuyuk, A; Gul, H; Gunal, A; Kunak, ZI; Macit, E; Yucel, O, 2008) |
| "The efficacy and tolerability of taurolidine, an antibacterial substance, was evaluated in a phase 2 trial enrolling patients with advanced melanoma." | 5.15 | The antibacterial substance, taurolidine in the second/third-line treatment of very advanced stage IV melanoma including brain metastases: results of a phase 2, open-label study. ( Baumann, K; Dummer, R; French, LE; Goldinger, SM; Imhof, L; Röthlisberger, P; Schad, K, 2011) |
| "The purpose of this study to assess the effect of the formula taurine/diltiazem/vitamin E on the progression of visual field loss in retinitis pigmentosa." | 5.10 | Treatment with taurine, diltiazem, and vitamin E retards the progressive visual field reduction in retinitis pigmentosa: a 3-year follow-up study. ( Pasantes-Morales, H; Quesada, O; Quiroz, H, 2002) |
| "Topical liposomal MgT delays cataractogenesis in galactose-fed rats by maintaining the lens mineral homeostasis and reducing lenticular oxidative and nitrosative stress." | 3.83 | Mechanism of the anticataract effect of liposomal MgT in galactose-fed rats. ( Agarwal, P; Agarwal, R; Alyautdin, R; Iezhitsa, I; Ismail, NM; Krasilnikova, A; Ozerov, A; Rahman, TH; Rozali, KN; Saad, SD; Spasov, A; Zakaria, FK, 2016) |
| "Disease progression was investigated at 4 time points, from 9 to 18 months of age, and in 4 regions: cortex, hippocampus, striatum, and thalamus." | 1.72 | Spatio-temporal metabolic rewiring in the brain of TgF344-AD rat model of Alzheimer's disease. ( López-Gil, X; Muñoz-Moreno, E; Simões, RV; Soria, G; Tudela, R, 2022) |
| "Taurine was higher in the serum from SLE patients compared to healthy controls (P < 0." | 1.56 | Taurine Metabolism Aggravates the Progression of Lupus by Promoting the Function of Plasmacytoid Dendritic Cells. ( Ding, H; Fu, Q; Guo, Q; Li, G; Li, J; Meng, Y; Shen, N; Ye, Z; Yin, Z; Zhou, H, 2020) |
| "Taurine treatment reverted all the above changes induced by DMBA and inhibited the development of rat breast carcinoma through its ability to induce apoptosis." | 1.48 | Taurine abrogates mammary carcinogenesis through induction of apoptosis in Sprague-Dawley rats. ( Anandakumar, P; Sakthisekaran, D; Vanitha, MK, 2018) |
| "BACKGROUND Colon cancer is one of the most prevalent and deadly cancers worldwide." | 1.43 | Overexpression of Long Non-Coding RNA TUG1 Promotes Colon Cancer Progression. ( Hu, JC; Jiang, LX; Qu, Z; Sui, MH; Sun, HQ; Yu, X; Zhai, HY; Zheng, HT; Zhou, K, 2016) |
| "Atherosclerosis is a multifactorial and progressive disease commonly correlated with a high fat diet." | 1.40 | Serum metabonomic analysis of apoE(-/-) mice reveals progression axes for atherosclerosis based on NMR spectroscopy. ( Guo, J; Li, J; Li, X; Liu, Y; Wang, L; Wu, T; Yang, Y; Yuan, F; Zhang, Q; Zheng, L, 2014) |
| "Taurine has also been shown to reduce lenticular oxidative stress." | 1.39 | Effects of magnesium taurate on the onset and progression of galactose-induced experimental cataract: in vivo and in vitro evaluation. ( Abdul Rahman, TH; Agarwal, P; Agarwal, R; Ahmad Fisol, NF; Awaludin, NA; Bakar, NS; Iezhitsa, I; Mohamed Ahmed Salama, MS; Mohd Ismail, N; Ozerov, A; Spasov, A, 2013) |
| "Spinocerebellar ataxia type 1 (SCA1) is a hereditary, progressive and fatal movement disorder that primarily affects the cerebellum." | 1.39 | Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1. ( Brent Clark, H; Eberly, LE; Emir, UE; Öz, G; Vollmers, ML, 2013) |
| "We show that disease progression in the TgP347L rabbit closely tracks human cone-sparing RP, including the cone-associated preservation of bipolar cell signaling and triggering of reprogramming." | 1.37 | Retinal remodeling in the Tg P347L rabbit, a large-eye model of retinal degeneration. ( Anderson, J; Jones, BW; Kondo, M; Lin, Y; Marc, RE; Rapp, K; Shaw, MV; Terasaki, H; Watt, CB; Yang, JH, 2011) |
| "Re-expansion pulmonary edema (RPE) is an acute, rare and potentially lethal complication." | 1.35 | Protective efficiacy of taurine against pulmonary edema progression: experimental study. ( Genc, O; Gozubuyuk, A; Gul, H; Gunal, A; Kunak, ZI; Macit, E; Yucel, O, 2008) |
| "Two weeks after induction of hydrocephalus the taurine concentration was decreased, whereas the concentration of [1,2-13C]lactate was increased in the cerebrum and that of [1,2-13C]GABA in the brainstem." | 1.32 | Astrocyte metabolism is disturbed in the early development of experimental hydrocephalus. ( Brinker, T; Kondziella, D; Lüdemann, W; Qu, H; Sletvold, O; Sonnewald, U, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 7 (21.21) | 29.6817 |
| 2010's | 15 (45.45) | 24.3611 |
| 2020's | 9 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, T | 1 |
| Zhou, K | 2 |
| Sun, T | 1 |
| Sang, C | 1 |
| Jia, W | 1 |
| Xie, G | 1 |
| Sengupta, P | 1 |
| Biswas, S | 1 |
| Roy, T | 1 |
| Muñoz-Moreno, E | 1 |
| Simões, RV | 1 |
| Tudela, R | 1 |
| López-Gil, X | 1 |
| Soria, G | 1 |
| Li, H | 1 |
| Xu, H | 2 |
| Li, Y | 1 |
| Jiang, Y | 1 |
| Hu, Y | 1 |
| Liu, T | 1 |
| Tian, X | 1 |
| Zhao, X | 1 |
| Zhu, Y | 1 |
| Wang, S | 1 |
| Zhang, C | 1 |
| Ge, J | 1 |
| Wang, X | 1 |
| Wen, H | 1 |
| Bai, C | 1 |
| Sun, Y | 1 |
| Song, L | 1 |
| Zhang, Y | 2 |
| Hui, R | 1 |
| Cai, J | 1 |
| Chen, J | 1 |
| Li, J | 2 |
| Ding, H | 1 |
| Meng, Y | 1 |
| Li, G | 1 |
| Fu, Q | 1 |
| Guo, Q | 1 |
| Yin, Z | 1 |
| Ye, Z | 1 |
| Zhou, H | 1 |
| Shen, N | 1 |
| Baliou, S | 1 |
| Kyriakopoulos, AM | 2 |
| Spandidos, DA | 1 |
| Zoumpourlis, V | 2 |
| Kong, T | 1 |
| Ren, X | 1 |
| Lin, S | 1 |
| Li, S | 1 |
| Gong, Y | 1 |
| Tian, J | 1 |
| Song, M | 1 |
| Kaufman, DL | 1 |
| Hanafy, MM | 1 |
| Lindeque, JZ | 1 |
| El-Maraghy, SA | 1 |
| Abdel-Hamid, AZ | 1 |
| Shahin, NN | 1 |
| Barker, RG | 1 |
| Wyckelsma, VL | 1 |
| Murphy, RM | 1 |
| Gambino, CM | 1 |
| Di Bona, D | 1 |
| Aiello, A | 1 |
| Carru, C | 1 |
| Duro, G | 1 |
| Guggino, G | 1 |
| Ferrante, A | 1 |
| Zinellu, A | 1 |
| Caruso, C | 1 |
| Candore, G | 1 |
| Accardi, G | 1 |
| Vanitha, MK | 1 |
| Anandakumar, P | 1 |
| Sakthisekaran, D | 1 |
| Chen, DQ | 1 |
| Cao, G | 1 |
| Chen, H | 1 |
| Argyopoulos, CP | 1 |
| Yu, H | 1 |
| Su, W | 1 |
| Chen, L | 1 |
| Samuels, DC | 1 |
| Zhuang, S | 1 |
| Bayliss, GP | 1 |
| Zhao, S | 1 |
| Yu, XY | 1 |
| Vaziri, ND | 1 |
| Wang, M | 1 |
| Liu, D | 1 |
| Mao, JR | 1 |
| Ma, SX | 1 |
| Zhao, J | 1 |
| Shang, YQ | 1 |
| Kang, H | 1 |
| Ye, F | 1 |
| Cheng, XH | 1 |
| Li, XR | 1 |
| Zhang, L | 1 |
| Meng, MX | 1 |
| Guo, Y | 1 |
| Zhao, YY | 1 |
| Agarwal, R | 2 |
| Iezhitsa, I | 2 |
| Awaludin, NA | 1 |
| Ahmad Fisol, NF | 1 |
| Bakar, NS | 1 |
| Agarwal, P | 2 |
| Abdul Rahman, TH | 1 |
| Spasov, A | 2 |
| Ozerov, A | 2 |
| Mohamed Ahmed Salama, MS | 1 |
| Mohd Ismail, N | 1 |
| DeSantis, SM | 1 |
| Bandyopadhyay, D | 1 |
| Baker, NL | 1 |
| Randall, PK | 1 |
| Anton, RF | 1 |
| Prisciandaro, JJ | 1 |
| Emir, UE | 1 |
| Brent Clark, H | 1 |
| Vollmers, ML | 1 |
| Eberly, LE | 1 |
| Öz, G | 1 |
| Hoffman, RP | 1 |
| Yang, Y | 1 |
| Liu, Y | 1 |
| Zheng, L | 1 |
| Wu, T | 1 |
| Zhang, Q | 1 |
| Li, X | 1 |
| Yuan, F | 1 |
| Wang, L | 1 |
| Guo, J | 1 |
| Logotheti, S | 1 |
| Khoury, N | 1 |
| Vlahopoulos, SA | 1 |
| Skourti, E | 1 |
| Papaevangeliou, D | 1 |
| Liloglou, T | 1 |
| Gorgoulis, V | 1 |
| Budunova, I | 1 |
| Saad, SD | 1 |
| Zakaria, FK | 1 |
| Krasilnikova, A | 1 |
| Rahman, TH | 1 |
| Rozali, KN | 1 |
| Alyautdin, R | 1 |
| Ismail, NM | 1 |
| Zhai, HY | 1 |
| Sui, MH | 1 |
| Yu, X | 1 |
| Qu, Z | 1 |
| Hu, JC | 1 |
| Sun, HQ | 1 |
| Zheng, HT | 1 |
| Jiang, LX | 1 |
| Higo, S | 1 |
| Miyata, S | 1 |
| Jiang, QY | 1 |
| Kitazawa, R | 1 |
| Kitazawa, S | 1 |
| Kasuga, M | 1 |
| Yucel, O | 1 |
| Kunak, ZI | 1 |
| Macit, E | 1 |
| Gunal, A | 1 |
| Gozubuyuk, A | 1 |
| Gul, H | 1 |
| Genc, O | 1 |
| Imhof, L | 1 |
| Goldinger, SM | 1 |
| Baumann, K | 1 |
| Schad, K | 1 |
| French, LE | 1 |
| Röthlisberger, P | 1 |
| Dummer, R | 1 |
| Jones, BW | 1 |
| Kondo, M | 1 |
| Terasaki, H | 1 |
| Watt, CB | 1 |
| Rapp, K | 1 |
| Anderson, J | 1 |
| Lin, Y | 1 |
| Shaw, MV | 1 |
| Yang, JH | 1 |
| Marc, RE | 1 |
| Akira, K | 1 |
| Masu, S | 1 |
| Imachi, M | 1 |
| Mitome, H | 1 |
| Hashimoto, T | 1 |
| De Luca, A | 2 |
| Pierno, S | 2 |
| Liantonio, A | 2 |
| Conte Camerino, D | 2 |
| Pasantes-Morales, H | 1 |
| Quiroz, H | 1 |
| Quesada, O | 1 |
| Cetrone, M | 1 |
| Camerino, C | 1 |
| Fraysse, B | 1 |
| Mirabella, M | 1 |
| Servidei, S | 1 |
| Rüegg, UT | 1 |
| Kondziella, D | 1 |
| Qu, H | 1 |
| Lüdemann, W | 1 |
| Brinker, T | 1 |
| Sletvold, O | 1 |
| Sonnewald, U | 1 |
| O'Brien, CP | 1 |
| Do, KQ | 1 |
| Lauer, CJ | 1 |
| Schreiber, W | 1 |
| Zollinger, M | 1 |
| Gutteck-Amsler, U | 1 |
| Cuénod, M | 1 |
| Holsboer, F | 1 |
| Stover, JF | 1 |
| Morganti-Kosmann, MC | 1 |
| Lenzlinger, PM | 1 |
| Stocker, R | 1 |
| Kempski, OS | 1 |
| Kossmann, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease[NCT05719714] | Phase 1/Phase 2 | 60 participants (Anticipated) | Interventional | 2023-11-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for taurine and Disease Exacerbation
| Article | Year |
|---|---|
Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics? (Review).
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Proliferation; Disease Models, Animal | 2020 |
Vascular endothelial dysfunction and nutritional compounds in early type 1 diabetes.
Topics: Adolescent; Antioxidants; Ascorbic Acid; Cardiovascular Diseases; Child; Diabetes Mellitus, Type 1; | 2014 |
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness.
Topics: Adrenal Cortex Hormones; Animals; Chloride Channels; Disease Progression; Dystrophin; Humans; Insuli | 2002 |
Research advances in the understanding and treatment of addiction.
Topics: Acamprosate; Alcohol Deterrents; Brain; Chronic Disease; Disease Progression; Humans; Naltrexone; Na | 2003 |
4 trials available for taurine and Disease Exacerbation
| Article | Year |
|---|---|
Comparative Study to Evaluate the Effect of Low-Protein Diet Supplementation with Taurine and N-Acetylcysteine, N-Acetylcysteine and Pyridoxamine Dihydrochloride in Preventing the Progression of Chronic Renal Failure in Patients with Non-Diabetic Kidney D
Topics: Acetylcysteine; Adult; Aged; Diet, Protein-Restricted; Dietary Supplements; Disease Progression; Fem | 2022 |
Modeling longitudinal drinking data in clinical trials: an application to the COMBINE study.
Topics: Acamprosate; Adult; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Cognitive Behavioral Therapy; | 2013 |
The antibacterial substance, taurolidine in the second/third-line treatment of very advanced stage IV melanoma including brain metastases: results of a phase 2, open-label study.
Topics: Adult; Aged; Anti-Infective Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Prot | 2011 |
Treatment with taurine, diltiazem, and vitamin E retards the progressive visual field reduction in retinitis pigmentosa: a 3-year follow-up study.
Topics: Adolescent; Adult; Angiography; Antioxidants; Calcium Channel Blockers; Child; Diltiazem; Disease Pr | 2002 |
25 other studies available for taurine and Disease Exacerbation
| Article | Year |
|---|---|
Altered bile acid glycine : taurine ratio in the progression of chronic liver disease.
Topics: Bile Acids and Salts; Case-Control Studies; Chronic Disease; Disease Progression; Female; Glycine; H | 2022 |
Spatio-temporal metabolic rewiring in the brain of TgF344-AD rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Choline; Creatine; Disease Models, Animal; Disease Progression; G | 2022 |
Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms.
Topics: Animals; Case-Control Studies; Clostridiaceae; Cohort Studies; Disease Progression; Fecal Microbiota | 2020 |
Taurine Metabolism Aggravates the Progression of Lupus by Promoting the Function of Plasmacytoid Dendritic Cells.
Topics: Animals; Dendritic Cells; Disease Progression; Female; Humans; Interferon Regulatory Factor-7; Lupus | 2020 |
Elucidation of metabolic responses in mud crab Scylla paramamosain challenged to WSSV infection by integration of metabolomics and transcriptomics.
Topics: Animals; Arthropod Proteins; ATP-Binding Cassette Transporters; Brachyura; Disease Progression; DNA | 2020 |
Homotaurine limits the spreading of T cell autoreactivity within the CNS and ameliorates disease in a model of multiple sclerosis.
Topics: Animals; Antigen Presentation; Antigen-Presenting Cells; Cell Proliferation; Central Nervous System; | 2021 |
Time-based investigation of urinary metabolic markers for Type 2 diabetes: Metabolomics approach for diabetes management.
Topics: Animals; Biomarkers; Carnitine; Cluster Analysis; Deoxyglucose; Diabetes Mellitus, Experimental; Dis | 2021 |
Mitochondrial content is preserved throughout disease progression in the mdx mouse model of Duchenne muscular dystrophy, regardless of taurine supplementation.
Topics: Animals; Citrate (si)-Synthase; Dietary Supplements; Disease Models, Animal; Disease Progression; El | 2018 |
HLA-C1 ligands are associated with increased susceptibility to systemic lupus erythematosus.
Topics: Adult; Case-Control Studies; Disease Progression; Female; Genetic Association Studies; HLA-C Antigen | 2018 |
Taurine abrogates mammary carcinogenesis through induction of apoptosis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogens; Caspa | 2018 |
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
Topics: Acetylcarnitine; Animals; Canavanine; Carnitine; Case-Control Studies; Disease Models, Animal; Disea | 2019 |
Effects of magnesium taurate on the onset and progression of galactose-induced experimental cataract: in vivo and in vitro evaluation.
Topics: Administration, Oral; Administration, Topical; Animals; Calcium; Catalase; Cataract; Diabetes Mellit | 2013 |
Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1.
Topics: Animals; Ataxin-1; Ataxins; Cerebellum; Choline; Disease Models, Animal; Disease Progression; Gene K | 2013 |
Serum metabonomic analysis of apoE(-/-) mice reveals progression axes for atherosclerosis based on NMR spectroscopy.
Topics: Animals; Atherosclerosis; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Choline; Diet, High-Fat; D | 2014 |
N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor.
Topics: Animals; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Models | 2016 |
Mechanism of the anticataract effect of liposomal MgT in galactose-fed rats.
Topics: Animals; Calcium; Calpain; Cataract; Disease Progression; Galactose; Homeostasis; Lens, Crystalline; | 2016 |
Overexpression of Long Non-Coding RNA TUG1 Promotes Colon Cancer Progression.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colo | 2016 |
Taurine administration after appearance of proteinuria retards progression of diabetic nephropathy in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Blood Glucose; Body Weight; Deoxyguanosine; Diabet | 2008 |
Protective efficiacy of taurine against pulmonary edema progression: experimental study.
Topics: Animals; Antioxidants; Disease Progression; Glutathione Peroxidase; Lung; Malondialdehyde; Pneumotho | 2008 |
Retinal remodeling in the Tg P347L rabbit, a large-eye model of retinal degeneration.
Topics: Adult; Animals; Animals, Genetically Modified; Disease Models, Animal; Disease Progression; Electror | 2011 |
A metabonomic study of biochemical changes characteristic of genetically hypertensive rats based on (1)H NMR spectroscopic urinalysis.
Topics: Animals; Citric Acid; Creatine; Disease Progression; Hippurates; Hypertension; Magnetic Resonance Sp | 2012 |
Enhanced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growth factor-1.
Topics: Animals; Creatine; Disease Progression; Electrophysiology; Insulin-Like Growth Factor I; Ion Channel | 2003 |
Astrocyte metabolism is disturbed in the early development of experimental hydrocephalus.
Topics: Acetates; Animals; Astrocytes; Biomarkers; Brain Stem; Carbon Isotopes; Disease Models, Animal; Dise | 2003 |
gamma-Glutamylglutamine and taurine concentrations are decreased in the cerebrospinal fluid of drug-naive patients with schizophrenic disorders.
Topics: Adult; Aging; Chromatography, High Pressure Liquid; Dipeptides; Discriminant Analysis; Disease Progr | 1995 |
Glutamate and taurine are increased in ventricular cerebrospinal fluid of severely brain-injured patients.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Brain Concussion; Brain Edema; Brain Injuries; Cerebr | 1999 |