taurine has been researched along with Diabetes Mellitus, Type 1 in 27 studies
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Taurine treatment significantly improved LV systolic and diastolic function, and there were persistent increases in activities of Akt/PKB and SOD, and the level of HO-1 protein." | 5.39 | Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats. ( Li, W; Lu, XH; Wang, GG; Xu, L; Zhao, X, 2013) |
| "We hypothesised that nutritional taurine, which is important for the development of the endocrine pancreas and reduces cytokine-induced apoptosis in pancreatic beta cells, would prevent or delay the onset of autoimmune diabetes, if given early in life to the non-obese diabetic (NOD) mouse." | 3.72 | Taurine supplement in early life altered islet morphology, decreased insulitis and delayed the onset of diabetes in non-obese diabetic mice. ( Arany, E; Hill, DJ; Remacle, C; Reusens, B; Romanus, P; Strutt, B, 2004) |
| " Peripheral insulin resistance, which usually responds to a very-low-fat diet, aerobic exercise training, and appropriate weight loss, can also treated with high-dose chromium picolinate, high-dose vitamin E, magnesium, soluble fiber, and possibly taurine; these measures appear likely to correct the diabetes-associated metabolic derangements of vascular smooth muscle, and thus lessen risk for macrovascular disease." | 3.69 | Exploiting complementary therapeutic strategies for the treatment of type II diabetes and prevention of its complications. ( McCarty, MF, 1997) |
| "Type 1 diabetes mellitus was induced in male rats by using streptozotocin." | 1.43 | Taurine Supplementation Improves Erectile Function in Rats with Streptozotocin-induced Type 1 Diabetes via Amelioration of Penile Fibrosis and Endothelial Dysfunction. ( Li, M; Liu, J; Rao, K; Ruan, Y; Wang, S; Wang, T; Yang, J; Yang, W; Ye, Z, 2016) |
| "Taurine treatment significantly improved LV systolic and diastolic function, and there were persistent increases in activities of Akt/PKB and SOD, and the level of HO-1 protein." | 1.39 | Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats. ( Li, W; Lu, XH; Wang, GG; Xu, L; Zhao, X, 2013) |
| "Type 1 diabetes is a prevalent chronic disease in childhood with the commonest single cause of death being cerebral oedema in the context of diabetic ketoacidosis (DKA)." | 1.33 | Insights into the acute cerebral metabolic changes associated with childhood diabetes. ( Cameron, FJ; Inder, TE; Kean, MJ; Neil, JJ; Wellard, RM; Werther, GA, 2005) |
| "Taurine-treated islets showed significant reduction in lipid peroxidation (0." | 1.31 | Islet cryopreservation: improved recovery following taurine pretreatment. ( Bhonde, RR; Hardikar, AA; Hoet, JJ; Remacle, C; Reusens, B; Risbud, MV, 2001) |
| "Taurine was given in drinking water at the level of 5% (w/v) for seven days." | 1.30 | Effect of taurine supplementation on the lipid peroxide formation and the activities of glutathione-related enzymes in the liver and islet of type I and II diabetic model mice. ( Kim, H; Lim, E; Park, S, 1998) |
| "Taurine was without significant effect on the time course of the Ca2+ transient decay in control cells, however, in diabetic cells it significantly accelerated the rate of decay." | 1.30 | Acute effects of taurine on intracellular calcium in normal and diabetic cardiac myocytes. ( Holloway, C; Kotsanas, G; Wendt, I, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 7 (25.93) | 29.6817 |
| 2010's | 13 (48.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tian, J | 1 |
| Dang, H | 1 |
| O'Laco, KA | 1 |
| Song, M | 1 |
| Tiu, BC | 1 |
| Gilles, S | 1 |
| Zakarian, C | 1 |
| Kaufman, DL | 1 |
| Gomez, R | 1 |
| Caletti, G | 1 |
| Arbo, BD | 1 |
| Hoefel, AL | 1 |
| Schneider, R | 1 |
| Hansen, AW | 1 |
| Pulcinelli, RR | 1 |
| Freese, L | 1 |
| Bandiera, S | 1 |
| Kucharski, LC | 1 |
| Barros, HMT | 1 |
| Manna, P | 1 |
| Das, J | 1 |
| Sil, PC | 1 |
| Wang, GG | 1 |
| Li, W | 1 |
| Lu, XH | 1 |
| Zhao, X | 1 |
| Xu, L | 1 |
| Hoffman, RP | 1 |
| Bessho, M | 1 |
| Murase-Mishiba, Y | 1 |
| Imagawa, A | 1 |
| Terasaki, J | 1 |
| Hanafusa, T | 1 |
| Ribeiro, RA | 1 |
| Santos-Silva, JC | 1 |
| Vettorazzi, JF | 1 |
| Cotrim, BB | 1 |
| Boschero, AC | 1 |
| Carneiro, EM | 1 |
| Zhang, H | 1 |
| Huang, M | 1 |
| Gao, L | 1 |
| Lei, H | 1 |
| Ruan, Y | 2 |
| Li, M | 2 |
| Wang, T | 2 |
| Yang, J | 2 |
| Rao, K | 2 |
| Wang, S | 2 |
| Yang, W | 2 |
| Liu, J | 2 |
| Ye, Z | 2 |
| Li, J | 1 |
| Qin, F | 1 |
| Yuan, J | 1 |
| Gavrovskaya, LK | 1 |
| Ryzhova, OV | 1 |
| Safonova, AF | 1 |
| Matveev, AK | 1 |
| Sapronov, NS | 1 |
| Jensen-Waern, M | 1 |
| Andersson, M | 1 |
| Kruse, R | 1 |
| Nilsson, B | 1 |
| Larsson, R | 1 |
| Korsgren, O | 1 |
| Essén-Gustavsson, B | 1 |
| Moloney, MA | 1 |
| Casey, RG | 1 |
| O'Donnell, DH | 1 |
| Fitzgerald, P | 1 |
| Thompson, C | 1 |
| Bouchier-Hayes, DJ | 1 |
| Ivanov, DA | 1 |
| Gnusaev, SF | 1 |
| Elizarova, EP | 2 |
| Iakovlev, BN | 1 |
| Arany, E | 1 |
| Strutt, B | 1 |
| Romanus, P | 1 |
| Remacle, C | 2 |
| Reusens, B | 2 |
| Hill, DJ | 1 |
| Cameron, FJ | 1 |
| Kean, MJ | 1 |
| Wellard, RM | 1 |
| Werther, GA | 1 |
| Neil, JJ | 1 |
| Inder, TE | 1 |
| Merheb, M | 1 |
| Daher, RT | 1 |
| Nasrallah, M | 1 |
| Sabra, R | 1 |
| Ziyadeh, FN | 1 |
| Barada, K | 1 |
| Franconi, F | 3 |
| Bennardini, F | 2 |
| Mattana, A | 2 |
| Miceli, M | 3 |
| Ciuti, M | 2 |
| Mian, M | 1 |
| Gironi, A | 2 |
| Anichini, R | 2 |
| Seghieri, G | 3 |
| Milan, M | 1 |
| Bartomomei, G | 1 |
| Fazzini, A | 1 |
| Caputo, S | 1 |
| DiLeo, MA | 1 |
| Lepore, D | 1 |
| Ghirlanda, G | 1 |
| Nedosugova, LV | 1 |
| McCarty, MF | 1 |
| Lim, E | 1 |
| Park, S | 1 |
| Kim, H | 1 |
| Holloway, C | 1 |
| Kotsanas, G | 1 |
| Wendt, I | 1 |
| Hardikar, AA | 1 |
| Risbud, MV | 1 |
| Hoet, JJ | 1 |
| Bhonde, RR | 1 |
| Rose, SJ | 1 |
| Bushi, M | 1 |
| Nagra, I | 1 |
| Davies, WE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Taurine on Glycemic, Lipid and Inflammatory Profile in Individuals With Type 2 Diabetes: a Randomized Clinical Trial[NCT04874012] | Phase 2 | 94 participants (Anticipated) | Interventional | 2021-06-12 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for taurine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Role of sulfur containing amino acids as an adjuvant therapy in the prevention of diabetes and its associated complications.
Topics: 3T3-L1 Cells; Amino Acids, Sulfur; Animals; Blood Glucose; Cells, Cultured; Cysteine; Diabetes Melli | 2013 |
Vascular endothelial dysfunction and nutritional compounds in early type 1 diabetes.
Topics: Adolescent; Antioxidants; Ascorbic Acid; Cardiovascular Diseases; Child; Diabetes Mellitus, Type 1; | 2014 |
3 trials available for taurine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Two weeks taurine supplementation reverses endothelial dysfunction in young male type 1 diabetics.
Topics: Adult; Blood Pressure; Brachial Artery; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetic Angi | 2010 |
Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation.
Topics: Adult; Arachidonic Acid; Blood Platelets; Diabetes Mellitus, Type 1; Dose-Response Relationship, Dru | 1995 |
First experiments in taurine administration for diabetes mellitus. The effect on erythrocyte membranes.
Topics: Adult; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 1; Di | 1996 |
22 other studies available for taurine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Homotaurine Treatment Enhances CD4
Topics: Animals; Blood Glucose; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Diabetes Mellitus, E | 2019 |
Acute intraperitoneal administration of taurine decreases the glycemia and reduces food intake in type 1 diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Eating; Hypoglyc | 2018 |
Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats.
Topics: Animals; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Diabetes Me | 2013 |
Possible contribution of taurine to distorted glucagon secretion in intra-islet insulin deficiency: a metabolome analysis using a novel α-cell model of insulin-deficient diabetes.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Gene Knockdown Techn | 2014 |
Taurine Supplementation Enhances Insulin Secretion Without Altering Islet Morphology in Non-obese Diabetic Mice.
Topics: Animals; Animals, Newborn; Cell Size; Cells, Cultured; Diabetes Mellitus, Type 1; Female; Insulin; I | 2015 |
Region-specific cerebral metabolic alterations in streptozotocin-induced type 1 diabetic rats: an in vivo proton magnetic resonance spectroscopy study.
Topics: Animals; Aspartic Acid; Blood Glucose; Brain Chemistry; Corpus Striatum; Diabetes Mellitus, Experime | 2015 |
Taurine Supplementation Improves Erectile Function in Rats with Streptozotocin-induced Type 1 Diabetes via Amelioration of Penile Fibrosis and Endothelial Dysfunction.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Male; Penile Erection; Penis; R | 2016 |
Re: Taurine Supplementation Improves Erectile Function in Rats With Streptozotocin-Induced Type 1 Diabetes via Amelioration of Penile Fibrosis and Endothelial Dysfunction (J Sex Med 2016;13:778-785).
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Erectile Dysfunction; Humans; M | 2016 |
Response and Rebuttal to Letter to the Editor regarding "Taurine Supplementation Improves Erectile Function in Rats with Streptozotocin-Induced Type 1 Diabetes via Amelioration of Penile Fibrosis and Endothelial Dysfunction".
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Erectile Dysfunction; Humans; M | 2016 |
Protective effect of taurine on rats with experimental insulin-dependent diabetes mellitus.
Topics: Animals; Body Weight; C-Peptide; Cell Count; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ | 2008 |
Effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Glucose; Body Weight; C-Peptide; D | 2009 |
[Efficacy of metabolic therapy in prevention and treatment of adolescents with diabetic autonomic cardiovascular neuropathy].
Topics: Adolescent; Blood Pressure; Chemoprevention; Child; Diabetes Mellitus, Type 1; Diabetic Neuropathies | 2010 |
Taurine supplement in early life altered islet morphology, decreased insulitis and delayed the onset of diabetes in non-obese diabetic mice.
Topics: Animals; Diabetes Mellitus, Type 1; Dietary Supplements; Female; Insulin; Islets of Langerhans; Male | 2004 |
Insights into the acute cerebral metabolic changes associated with childhood diabetes.
Topics: Adolescent; Brain; Brain Edema; Child; Diabetes Mellitus, Type 1; Female; Humans; Magnetic Resonance | 2005 |
Taurine intestinal absorption and renal excretion test in diabetic patients: a pilot study.
Topics: Adult; Body Mass Index; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fem | 2007 |
Taurine levels in plasma and platelets in insulin-dependent and non-insulin-dependent diabetes mellitus: correlation with platelet aggregation.
Topics: Adult; Blood Platelets; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Male; | 1994 |
Taurine and diabetes. Humans and experimental models.
Topics: Animals; Arachidonic Acid; Aspirin; Blood Platelets; Diabetes Mellitus, Experimental; Diabetes Melli | 1996 |
Exploiting complementary therapeutic strategies for the treatment of type II diabetes and prevention of its complications.
Topics: Complementary Therapies; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diet, Fat-Restricted; Die | 1997 |
Effect of taurine supplementation on the lipid peroxide formation and the activities of glutathione-related enzymes in the liver and islet of type I and II diabetic model mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1998 |
Acute effects of taurine on intracellular calcium in normal and diabetic cardiac myocytes.
Topics: Animals; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Electric Stimulation; | 1999 |
Islet cryopreservation: improved recovery following taurine pretreatment.
Topics: Animals; Blood Glucose; Cell Survival; Cryopreservation; Diabetes Mellitus, Type 1; Image Processing | 2001 |
Taurine fluxes in insulin dependent diabetes mellitus and rehydration in streptozotocin treated rats.
Topics: Animals; Brain; Brain Edema; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Ke | 2000 |