taurine has been researched along with Cystic Fibrosis in 33 studies
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Excerpt | Relevance | Reference |
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"Ursodeoxycholic acid administration has been reported to improve cholestasis and inflammatory activity in primary biliary cirrhosis and, in an uncontrolled study, also in young adults with cystic fibrosis (CF) and chronic cholestasis." | 9.07 | Effect of a medium dose of ursodeoxycholic acid with or without taurine supplementation on the nutritional status of patients with cystic fibrosis: a randomized, placebo-controlled, crossover trial. ( Angelico, M; Antonelli, M; Bertasi, S; De Santis, A; Diamanti, S; Goffredo, F; Martino, F; Merli, M; Quattrucci, S; Servi, R, 1994) |
"The effect of taurine supplementation (30 to 40 mg/kg/24 hr) on fat absorption and related measurements was examined in 21 preadolescent children with cystic fibrosis (CF) using a 12-month double-blind crossover technique." | 9.06 | Taurine supplementation, fat absorption, and growth in cystic fibrosis. ( Davidson, GP; Robb, TA; Thompson, GN, 1987) |
"The effect of taurine supplementation on the absorption of a fat meal was evaluated in patients with cystic fibrosis." | 9.06 | Taurine improves the absorption of a fat meal in patients with cystic fibrosis. ( Belli, DC; Darling, P; Giguère, R; Lepage, G; Leroy, C; Levy, E; Roy, CC, 1987) |
"Aerosol therapy with Prolastin in patients with cystic fibrosis leads to a progressive decrease in sputum taurine." | 7.73 | Prolastin aerosol therapy and sputum taurine in cystic fibrosis. ( Berthiaume, Y; Cantin, AM; Cloutier, D; Martel, M, 2006) |
"In 10 children with cystic fibrosis and persisting steatorrhoea, supplementation with taurine (30-40 mg/kg/day) was given for two months as an adjunct to the usual pancreatic enzyme treatment." | 7.68 | Effect of taurine supplementation on fat and energy absorption in cystic fibrosis. ( Ciccimarra, F; De Curtis, M; De Ritis, G; Ercolini, P; Garofalo, V; Santamaria, F; Vittoria, L, 1992) |
"We have evaluated the effect of taurine supplementation nutritional status, steatorrhea and bile acid in twenty two Cystic Fibrosis patients." | 7.68 | Effect of taurine supplements on growth, fat absorption and bile acid on cystic fibrosis. ( Carrasco, S; Codoceo, R; Lama, R; Polanco, I; Prieto, G, 1990) |
"The hydrophilic bile acid ursodeoxycholic acid (UDCA) has recently been shown to improve indexes of liver function in adult patients with various liver diseases." | 7.68 | Effects of ursodeoxycholic acid therapy for liver disease associated with cystic fibrosis. ( Colombo, C; Crosignani, A; Curcio, L; Giunta, A; Podda, M; Roda, A; Ronchi, M; Setchell, KD, 1990) |
"Eleven children with cystic fibrosis (CF) and pancreatic insufficiency were given supplementation with taurine (30-40 mg/kg/day) for 2 months, while taking their usual dosage of enzymatic therapy." | 7.67 | Effect of taurine supplementation on fat and bile acid absorption in patients with cystic fibrosis. ( Arlati, S; Colombo, C; Corbetta, C; Curcio, L; Garatti, M; Giunta, A; Maiavacca, R; Ronchi, M, 1988) |
"Taurine deficiency recently has been proposed to be clinically significant in cystic fibrosis (CF)." | 7.67 | Taurine uptake by normal and cystic fibrosis fibroblasts. ( Thompson, GN, 1988) |
"Bile acid taurine deficiency is common in cystic fibrosis (CF) and is thought to be associated with impaired fat absorption." | 7.67 | Assessment of taurine deficiency in cystic fibrosis. ( Thompson, GN, 1988) |
"Treatment with taurine was followed by a significant increase in serum prealbumin levels (P = ." | 6.68 | Ursodeoxycholic acid for liver disease associated with cystic fibrosis: a double-blind multicenter trial. The Italian Group for the Study of Ursodeoxycholic Acid in Cystic Fibrosis. ( Battezzati, PM; Bettinardi, N; Colombo, C; Giunta, A; Podda, M, 1996) |
"Taurine is a conditionally essential amino acid that possibly improves the micellar phase of fat digestion." | 6.67 | Taurine decreases fecal fatty acid and sterol excretion in cystic fibrosis. A randomized double-blind trial. ( Lacaille, F; Lamarre, A; Lepage, G; Ronco, N; Roy, CC; Smith, LJ, 1991) |
"On taurine, steatorrhea was reduced (p less than 0." | 6.66 | Effect of taurine supplements on fat absorption in cystic fibrosis. ( Darling, PB; Lepage, G; Leroy, C; Masson, P; Roy, CC, 1985) |
"Ursodeoxycholic acid administration has been reported to improve cholestasis and inflammatory activity in primary biliary cirrhosis and, in an uncontrolled study, also in young adults with cystic fibrosis (CF) and chronic cholestasis." | 5.07 | Effect of a medium dose of ursodeoxycholic acid with or without taurine supplementation on the nutritional status of patients with cystic fibrosis: a randomized, placebo-controlled, crossover trial. ( Angelico, M; Antonelli, M; Bertasi, S; De Santis, A; Diamanti, S; Goffredo, F; Martino, F; Merli, M; Quattrucci, S; Servi, R, 1994) |
"The effect of taurine supplementation (30 to 40 mg/kg/24 hr) on fat absorption and related measurements was examined in 21 preadolescent children with cystic fibrosis (CF) using a 12-month double-blind crossover technique." | 5.06 | Taurine supplementation, fat absorption, and growth in cystic fibrosis. ( Davidson, GP; Robb, TA; Thompson, GN, 1987) |
"The effect of taurine supplementation on the absorption of a fat meal was evaluated in patients with cystic fibrosis." | 5.06 | Taurine improves the absorption of a fat meal in patients with cystic fibrosis. ( Belli, DC; Darling, P; Giguère, R; Lepage, G; Leroy, C; Levy, E; Roy, CC, 1987) |
"Aerosol therapy with Prolastin in patients with cystic fibrosis leads to a progressive decrease in sputum taurine." | 3.73 | Prolastin aerosol therapy and sputum taurine in cystic fibrosis. ( Berthiaume, Y; Cantin, AM; Cloutier, D; Martel, M, 2006) |
"Airway secretions of cystic fibrosis patients were found to contain high concentrations of taurine, which decreased with antibiotic therapy during acute respiratory exacerbations." | 3.69 | Taurine modulation of hypochlorous acid-induced lung epithelial cell injury in vitro. Role of anion transport. ( Cantin, AM, 1994) |
"We evaluated long-lived oxidant potential in the sputum of patients with cystic fibrosis (CF) by quantitating the methionine-inhibitable, long-lived oxidant fraction of sputum, referred to as the chloramines." | 3.69 | Neutrophil-derived long-lived oxidants in cystic fibrosis sputum. ( Bardet, J; Delacourt, C; Descamps-Latscha, B; Nguyen, AT; Rabier, D; Witko-Sarsat, V, 1995) |
"In 10 children with cystic fibrosis and persisting steatorrhoea, supplementation with taurine (30-40 mg/kg/day) was given for two months as an adjunct to the usual pancreatic enzyme treatment." | 3.68 | Effect of taurine supplementation on fat and energy absorption in cystic fibrosis. ( Ciccimarra, F; De Curtis, M; De Ritis, G; Ercolini, P; Garofalo, V; Santamaria, F; Vittoria, L, 1992) |
"We have evaluated the effect of taurine supplementation nutritional status, steatorrhea and bile acid in twenty two Cystic Fibrosis patients." | 3.68 | Effect of taurine supplements on growth, fat absorption and bile acid on cystic fibrosis. ( Carrasco, S; Codoceo, R; Lama, R; Polanco, I; Prieto, G, 1990) |
"The hydrophilic bile acid ursodeoxycholic acid (UDCA) has recently been shown to improve indexes of liver function in adult patients with various liver diseases." | 3.68 | Effects of ursodeoxycholic acid therapy for liver disease associated with cystic fibrosis. ( Colombo, C; Crosignani, A; Curcio, L; Giunta, A; Podda, M; Roda, A; Ronchi, M; Setchell, KD, 1990) |
"Eleven children with cystic fibrosis (CF) and pancreatic insufficiency were given supplementation with taurine (30-40 mg/kg/day) for 2 months, while taking their usual dosage of enzymatic therapy." | 3.67 | Effect of taurine supplementation on fat and bile acid absorption in patients with cystic fibrosis. ( Arlati, S; Colombo, C; Corbetta, C; Curcio, L; Garatti, M; Giunta, A; Maiavacca, R; Ronchi, M, 1988) |
"Taurine deficiency recently has been proposed to be clinically significant in cystic fibrosis (CF)." | 3.67 | Taurine uptake by normal and cystic fibrosis fibroblasts. ( Thompson, GN, 1988) |
"Bile acid taurine deficiency is common in cystic fibrosis (CF) and is thought to be associated with impaired fat absorption." | 3.67 | Assessment of taurine deficiency in cystic fibrosis. ( Thompson, GN, 1988) |
" Results of this study thus show that the mathematical ASL model combined with the lung deposition model can be an effective tool for helping decide the optimum dosage of inhaled antibiotic drugs delivered during human clinical trials." | 2.73 | Estimating in vivo airway surface liquid concentration in trials of inhaled antibiotics. ( Hasan, MA; Lange, CF, 2007) |
"Treatment with taurine was followed by a significant increase in serum prealbumin levels (P = ." | 2.68 | Ursodeoxycholic acid for liver disease associated with cystic fibrosis: a double-blind multicenter trial. The Italian Group for the Study of Ursodeoxycholic Acid in Cystic Fibrosis. ( Battezzati, PM; Bettinardi, N; Colombo, C; Giunta, A; Podda, M, 1996) |
"Taurine is a conditionally essential amino acid that possibly improves the micellar phase of fat digestion." | 2.67 | Taurine decreases fecal fatty acid and sterol excretion in cystic fibrosis. A randomized double-blind trial. ( Lacaille, F; Lamarre, A; Lepage, G; Ronco, N; Roy, CC; Smith, LJ, 1991) |
"On taurine, steatorrhea was reduced (p less than 0." | 2.66 | Effect of taurine supplements on fat absorption in cystic fibrosis. ( Darling, PB; Lepage, G; Leroy, C; Masson, P; Roy, CC, 1985) |
"Bile is lithogenic in untreated cystic fibrosis and responds to pancreatic enzymes." | 1.26 | Abnormal biliary lipid composition in cystic fibrosis. Effect of pancreatic enzymes. ( Combes, JC; Lasalle, R; Mégevand, A; Morin, CL; Nusslé, D; Roy, CC; Weber, AM, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 13 (39.39) | 18.7374 |
1990's | 11 (33.33) | 18.2507 |
2000's | 6 (18.18) | 29.6817 |
2010's | 1 (3.03) | 24.3611 |
2020's | 2 (6.06) | 2.80 |
Authors | Studies |
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Tabori, H | 1 |
Schneider, J | 1 |
Lüth, S | 1 |
Zagoya, C | 1 |
Barucha, A | 1 |
Lehmann, T | 1 |
Kauf, E | 1 |
Barth, A | 1 |
Mainz, JG | 1 |
Leiter, H | 1 |
Toepfer, S | 1 |
Messner, P | 1 |
Rabensteiner, M | 1 |
Gostner, JM | 1 |
Lackner, M | 1 |
Hermann, M | 1 |
Nagl, M | 1 |
Zeriouh, M | 1 |
Sabashnikov, A | 1 |
Patil, NP | 1 |
Schmack, B | 1 |
Zych, B | 1 |
Mohite, PN | 1 |
García Sáez, D | 1 |
Koch, A | 1 |
Mansur, A | 1 |
Soresi, S | 1 |
Weymann, A | 1 |
Marczin, N | 1 |
Wahlers, T | 1 |
De Robertis, F | 1 |
Simon, AR | 1 |
Popov, AF | 1 |
Perry, JD | 1 |
Riley, G | 1 |
Johnston, S | 1 |
Dark, JH | 1 |
Gould, FK | 1 |
Cantin, AM | 2 |
Berthiaume, Y | 1 |
Cloutier, D | 1 |
Martel, M | 1 |
Hasan, MA | 1 |
Lange, CF | 1 |
Merli, M | 1 |
Bertasi, S | 1 |
Servi, R | 1 |
Diamanti, S | 1 |
Martino, F | 1 |
De Santis, A | 1 |
Goffredo, F | 1 |
Quattrucci, S | 1 |
Antonelli, M | 1 |
Angelico, M | 1 |
Witko-Sarsat, V | 1 |
Delacourt, C | 1 |
Rabier, D | 1 |
Bardet, J | 1 |
Nguyen, AT | 1 |
Descamps-Latscha, B | 1 |
O'Connor, PJ | 1 |
Southern, KW | 1 |
Bowler, IM | 1 |
Irving, HC | 1 |
Robinson, PJ | 1 |
Littlewood, JM | 1 |
Colombo, C | 4 |
Battezzati, PM | 2 |
Podda, M | 2 |
Bettinardi, N | 1 |
Giunta, A | 4 |
Thinnes, FP | 1 |
Hellmann, KP | 1 |
Hellmann, T | 1 |
Merker, R | 1 |
Schwarzer, C | 1 |
Walter, G | 1 |
Götz, H | 1 |
Hilschmann, N | 1 |
Ledson, MJ | 1 |
Gallagher, MJ | 1 |
Robinson, M | 1 |
Cowperthwaite, C | 1 |
Williets, T | 1 |
Hart, CA | 1 |
Walshaw, MJ | 1 |
Watkins, JB | 1 |
Perman, JA | 1 |
Lefebvre, D | 1 |
Ratelle, S | 1 |
Chartrand, L | 1 |
Roy, CC | 5 |
Weber, AM | 1 |
Morin, CL | 1 |
Combes, JC | 1 |
Nusslé, D | 1 |
Mégevand, A | 1 |
Lasalle, R | 1 |
De Curtis, M | 1 |
Santamaria, F | 1 |
Ercolini, P | 1 |
Vittoria, L | 1 |
De Ritis, G | 1 |
Garofalo, V | 1 |
Ciccimarra, F | 1 |
Smith, LJ | 1 |
Lacaille, F | 1 |
Lepage, G | 3 |
Ronco, N | 1 |
Lamarre, A | 1 |
Riely, CA | 1 |
Crosignani, A | 2 |
Assaisso, M | 1 |
Ronchi, M | 3 |
Carrasco, S | 1 |
Codoceo, R | 1 |
Prieto, G | 1 |
Lama, R | 1 |
Polanco, I | 1 |
Setchell, KD | 1 |
Roda, A | 1 |
Curcio, L | 2 |
Kendler, BS | 1 |
Thompson, GN | 5 |
Arlati, S | 1 |
Maiavacca, R | 1 |
Garatti, M | 1 |
Corbetta, C | 1 |
Robb, TA | 1 |
Davidson, GP | 1 |
Belli, DC | 1 |
Levy, E | 1 |
Darling, P | 1 |
Leroy, C | 2 |
Giguère, R | 1 |
Tomas, FM | 1 |
Darling, PB | 1 |
Masson, P | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Phase II Study: LYM-X-SORB™, an Organized Lipid Matrix: Fatty Acids and Choline in CF[NCT00406536] | Phase 2 | 110 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 reviews available for taurine and Cystic Fibrosis
Article | Year |
---|---|
Taurine - monograph.
Topics: Alcoholism; Alzheimer Disease; Animals; Cardiovascular Diseases; Cystic Fibrosis; Diabetes Mellitus; | 2001 |
Bile acid metabolism in infants and children.
Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cystic Fibrosis; Diarrhea; Digestive Syste | 1977 |
Taurine: an overview of its role in preventive medicine.
Topics: Animals; Cardiovascular Diseases; Cystic Fibrosis; Epilepsy; Humans; Infant, Newborn; Liver Diseases | 1989 |
Taurine supplementation in cystic fibrosis.
Topics: Adult; Cystic Fibrosis; Dietary Fats; Female; Humans; Infant; Intestinal Absorption; Male; Taurine | 1988 |
9 trials available for taurine and Cystic Fibrosis
Article | Year |
---|---|
Estimating in vivo airway surface liquid concentration in trials of inhaled antibiotics.
Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infe | 2007 |
Effect of a medium dose of ursodeoxycholic acid with or without taurine supplementation on the nutritional status of patients with cystic fibrosis: a randomized, placebo-controlled, crossover trial.
Topics: Absorption; Adolescent; Adult; Bile Acids and Salts; Child; Cross-Over Studies; Cystic Fibrosis; Die | 1994 |
Ursodeoxycholic acid for liver disease associated with cystic fibrosis: a double-blind multicenter trial. The Italian Group for the Study of Ursodeoxycholic Acid in Cystic Fibrosis.
Topics: 5'-Nucleotidase; Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Double-Blind Method; D | 1996 |
A randomized double-blinded placebo-controlled crossover trial of nebulized taurolidine in adult cystic fibrosis patients infected with Burkholderia cepacia.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Colony Coun | 2002 |
Taurine decreases fecal fatty acid and sterol excretion in cystic fibrosis. A randomized double-blind trial.
Topics: Adolescent; Adult; Body Height; Body Weight; Celiac Disease; Child; Cystic Fibrosis; Double-Blind Me | 1991 |
Taurine supplementation, fat absorption, and growth in cystic fibrosis.
Topics: Body Height; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Cystic Fibrosis; Dietar | 1987 |
Taurine improves the absorption of a fat meal in patients with cystic fibrosis.
Topics: Adult; Celiac Disease; Child; Cholesterol; Chylomicrons; Cystic Fibrosis; Dietary Fats; Fatty Acids; | 1987 |
Protein metabolism in cystic fibrosis: responses to malnutrition and taurine supplementation.
Topics: Child; Child, Preschool; Cystic Fibrosis; Diet; Dietary Proteins; Female; Humans; Male; Muscles; Pro | 1987 |
Effect of taurine supplements on fat absorption in cystic fibrosis.
Topics: Adolescent; Child; Child, Preschool; Cystic Fibrosis; Dietary Fats; Fatty Acids; Feces; Female; Huma | 1985 |
20 other studies available for taurine and Cystic Fibrosis
Article | Year |
---|---|
Elevated Levels of Toxic Bile Acids in Serum of Cystic Fibrosis Patients with
Topics: Bile Acids and Salts; Cholic Acid; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regula | 2022 |
Microbicidal activity of N-chlorotaurine can be enhanced in the presence of lung epithelial cells.
Topics: Anti-Infective Agents; Antifungal Agents; Candida albicans; Cells, Cultured; Cystic Fibrosis; Epithe | 2020 |
Use of taurolidine in lung transplantation for cystic fibrosis and impact on bacterial colonization.
Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Female; Humans; Lung Transplantation; Male; Middle Ag | 2018 |
Activity of disinfectants against Gram-negative bacilli isolated from patients undergoing lung transplantation for cystic fibrosis.
Topics: Anti-Infective Agents, Local; Burkholderia cepacia; Chlorhexidine; Cystic Fibrosis; Disinfectants; H | 2002 |
Prolastin aerosol therapy and sputum taurine in cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; alpha 1-Antitrypsin; Cystic Fibrosis; Female; Humans; | 2006 |
Taurine modulation of hypochlorous acid-induced lung epithelial cell injury in vitro. Role of anion transport.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Aged; Animals; Anions; Bronchitis; Cats; Ce | 1994 |
Neutrophil-derived long-lived oxidants in cystic fibrosis sputum.
Topics: Adolescent; Adult; Asthma; Child; Child, Preschool; Chloramines; Cystic Fibrosis; Forced Expiratory | 1995 |
The role of hepatobiliary scintigraphy in cystic fibrosis.
Topics: Adolescent; Adult; Biliary Tract; Child; Child, Preschool; Cystic Fibrosis; Female; Follow-Up Studie | 1996 |
Studies on human porin XXI: gadolinium opens Up cell membrane standing porin channels making way for the osmolytes chloride or taurine-A putative approach to activate the alternate chloride channel in cystic fibrosis.
Topics: Antibodies, Monoclonal; B-Lymphocytes; Biological Transport; Cell Line; Cell Size; Chloride Channels | 2000 |
Reduced microbial transformation of bile acids in cystic fibrosis.
Topics: Adolescent; Bile Acids and Salts; Chenodeoxycholic Acid; Child; Child, Preschool; Cholic Acids; Cyst | 1977 |
Abnormal biliary lipid composition in cystic fibrosis. Effect of pancreatic enzymes.
Topics: Bile; Bile Acids and Salts; Child; Cholelithiasis; Cholesterol; Cholic Acids; Cystic Fibrosis; Femal | 1977 |
Effect of taurine supplementation on fat and energy absorption in cystic fibrosis.
Topics: Adolescent; Celiac Disease; Child; Child, Preschool; Cystic Fibrosis; Dietary Fats; Energy Metabolis | 1992 |
Liver dysfunction in cystic fibrosis--beneficial effect of bile acid treatment.
Topics: Bile Acids and Salts; Child; Cholestasis; Cystic Fibrosis; Humans; Liver Function Tests; Taurine; Ur | 1991 |
Effects of taurine and ursodeoxycholic acid on liver function tests in patients with cystic fibrosis.
Topics: Bile Acids and Salts; Child; Cystic Fibrosis; Female; Humans; Liver Function Tests; Male; Taurine; U | 1990 |
Effect of taurine supplements on growth, fat absorption and bile acid on cystic fibrosis.
Topics: Adolescent; Adult; Bile Acids and Salts; Child; Child, Preschool; Cystic Fibrosis; Dietary Fats; Fem | 1990 |
Effects of ursodeoxycholic acid therapy for liver disease associated with cystic fibrosis.
Topics: Adolescent; Bile Acids and Salts; Child; Cystic Fibrosis; Deoxycholic Acid; Female; Humans; Liver Di | 1990 |
Failure of taurine to improve fat absorption in cystic fibrosis.
Topics: Adolescent; Child; Cystic Fibrosis; Female; Glycine; Humans; Intestinal Absorption; Lipid Metabolism | 1988 |
Effect of taurine supplementation on fat and bile acid absorption in patients with cystic fibrosis.
Topics: Bile Acids and Salts; Child; Cystic Fibrosis; Dietary Fats; Exocrine Pancreatic Insufficiency; Femal | 1988 |
Taurine uptake by normal and cystic fibrosis fibroblasts.
Topics: Calcium; Cells, Cultured; Cystic Fibrosis; Fibroblasts; Humans; Skin; Taurine | 1988 |
Assessment of taurine deficiency in cystic fibrosis.
Topics: Adolescent; Bile; Child; Child, Preschool; Cystic Fibrosis; Female; Glycine; Humans; Leukocytes; Liv | 1988 |