Page last updated: 2024-10-20

taurine and Cirrhosis

taurine has been researched along with Cirrhosis in 17 studies

Research Excerpts

ExcerptRelevanceReference
"Taurine treatment markedly reduced laminectomy-induced epidural fibrosis in rat models."7.83Taurine Reduced Epidural Fibrosis in Rat Models after Laminectomy via Downregulating EGR1. ( Cao, X; Chen, H; Ge, D; Ge, Y; Que, J; Sui, T; Tang, J; Yang, L, 2016)
" We reported that taurine had an anti-fibrotic effect in a dibutyltin dichloride (DBTC)-chronic pancreatitis model."7.78Effect of taurine on acinar cell apoptosis and pancreatic fibrosis in dibutyltin dichloride-induced chronic pancreatitis. ( Koide, N; Matsushita, K; Mizushima, T; Ochi, K; Sawa, K; Shirahige, A; Tanimoto, M; Tanioka, H, 2012)
"Pancreatic fibrosis induced by DBTC was improved remarkably by the oral administration of the taurine-containing diet."7.74Oral administration of taurine improves experimental pancreatic fibrosis. ( Ichimura, M; Koide, N; Matsushita, K; Mizushima, T; Ochi, K; Sawa, K; Shinji, T; Shirahige, A; Tanimoto, M; Tanioka, H, 2008)
" The aim of this study was to investigate the effects of taurine on oxidative capacity and fibrosis in experimental chronic rat pancreatic fibrosis."7.73Antioxidant treatment with taurine ameliorates chronic pancreatitis in an experimental rat model. ( Akay, C; Comert, B; Deveci, S; Inal, V; Isik, AT; Mas, MR; Mas, N; Tasci, I; Yamanel, L, 2006)
"This study was undertaken to investigate the effect of taurine on the infiltration of macrophages and the progression of renal interstitial fibrosis in the kidneys of rats treated with cisplatin (CDDP)."7.71Protective effect of taurine against renal interstitial fibrosis of rats induced by cisplatin. ( Hosokawa, T; Kurasaki, M; Saito, S; Saito, T; Sato, S; Yamate, J, 2002)
"Taurine (TAU) is an abundant amino acid with substantial anti-inflammatory and antioxidative properties."5.72Taurine mitigates the development of pulmonary inflammation, oxidative stress, and histopathological alterations in a rat model of bile duct ligation. ( Abdoli, N; Azarpira, N; Heidari, R; Lu, Y; Ma, Y; Manthari, RK; Mazloomi, S; Mehrabani, PS; Mingyu, Y; Mobasheri, A; Mousavifaraz, A; Nadgaran, A; Niknahad, H; Nikoozadeh, A; Ommati, MM; Rezaei, M; Sadeghian, I; Tang, Z; Xin, H; Xu, D, 2022)
"Taurine has been shown to protect against lung injury induced by various oxidants including ozone, nitrogen dioxide, amiodarone, and paraquat and to protect against bleomycin-induced lung injury in combination with niacin."5.35Protection of bleomycin-induced fibrosis and inflammation by taurine. ( Gordon, RE; Park, E; Park, SY; Schuller-Levis, G; Wang, C, 2009)
"Betaine or taurine was also found to decrease serum transaminase activities and hepatic lipid peroxidation without any change in hepatic antioxidant system in rats with hepatic fibrosis."5.32Betaine or taurine administration prevents fibrosis and lipid peroxidation induced by rat liver by ethanol plus carbon tetrachloride intoxication. ( Balkan, J; Cevikbaş, U; Erman, F; Koçak-Toker, N; Uysal, M, 2004)
" Molecular studies have shown that long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) participate in renal fibrosis, while the roles of lncRNA taurine upregulated gene 1 (TUG1) and miR-140-3p in hyperuricemia-induced renal fibrosis remain less investigated."4.12lncRNA TUG1 regulates hyperuricemia-induced renal fibrosis in a rat model. ( Hu, L; Ma, C; Wei, J; Zhang, H; Zhang, Y, 2022)
" The present study assessed the ability of taurine (TAU) to alleviate or prevent AMK-induced nephrotoxicity if co-administrated with AMK focusing on inflammation, apoptosis, and fibrosis."4.02The nephroprotective properties of taurine-amikacin treatment in rats are mediated through HSP25 and TLR-4 regulation. ( Azmy, A; El-Amir, A; Madbouly, N; Salama, A, 2021)
"Taurine treatment markedly reduced laminectomy-induced epidural fibrosis in rat models."3.83Taurine Reduced Epidural Fibrosis in Rat Models after Laminectomy via Downregulating EGR1. ( Cao, X; Chen, H; Ge, D; Ge, Y; Que, J; Sui, T; Tang, J; Yang, L, 2016)
" We reported that taurine had an anti-fibrotic effect in a dibutyltin dichloride (DBTC)-chronic pancreatitis model."3.78Effect of taurine on acinar cell apoptosis and pancreatic fibrosis in dibutyltin dichloride-induced chronic pancreatitis. ( Koide, N; Matsushita, K; Mizushima, T; Ochi, K; Sawa, K; Shirahige, A; Tanimoto, M; Tanioka, H, 2012)
"To study the differential expression of proteins between natural taurine treated hepatic stellate cells and controls, and investigate the underlying regulatory mechanism of natural taurine in inhibiting hepatic fibrosis."3.76Natural taurine promotes apoptosis of human hepatic stellate cells in proteomics analysis. ( Deng, X; Liang, J; Lin, ZX; Wu, FS; Zhang, YP; Zhang, ZW, 2010)
"Pancreatic fibrosis induced by DBTC was improved remarkably by the oral administration of the taurine-containing diet."3.74Oral administration of taurine improves experimental pancreatic fibrosis. ( Ichimura, M; Koide, N; Matsushita, K; Mizushima, T; Ochi, K; Sawa, K; Shinji, T; Shirahige, A; Tanimoto, M; Tanioka, H, 2008)
" The aim of this study was to investigate the effects of taurine on oxidative capacity and fibrosis in experimental chronic rat pancreatic fibrosis."3.73Antioxidant treatment with taurine ameliorates chronic pancreatitis in an experimental rat model. ( Akay, C; Comert, B; Deveci, S; Inal, V; Isik, AT; Mas, MR; Mas, N; Tasci, I; Yamanel, L, 2006)
"This study was undertaken to investigate the effect of taurine on the infiltration of macrophages and the progression of renal interstitial fibrosis in the kidneys of rats treated with cisplatin (CDDP)."3.71Protective effect of taurine against renal interstitial fibrosis of rats induced by cisplatin. ( Hosokawa, T; Kurasaki, M; Saito, S; Saito, T; Sato, S; Yamate, J, 2002)
"Taurine (TAU) is an abundant amino acid with substantial anti-inflammatory and antioxidative properties."1.72Taurine mitigates the development of pulmonary inflammation, oxidative stress, and histopathological alterations in a rat model of bile duct ligation. ( Abdoli, N; Azarpira, N; Heidari, R; Lu, Y; Ma, Y; Manthari, RK; Mazloomi, S; Mehrabani, PS; Mingyu, Y; Mobasheri, A; Mousavifaraz, A; Nadgaran, A; Niknahad, H; Nikoozadeh, A; Ommati, MM; Rezaei, M; Sadeghian, I; Tang, Z; Xin, H; Xu, D, 2022)
"Patients with biliary atresia (i."1.38Intestinal synthesis and secretion of bile salts as an adaptation to developmental biliary atresia in the sea lamprey. ( Chung-Davidson, YW; Li, K; Li, W; Wang, H; Yeh, CY, 2012)
"Taurine has been shown to protect against lung injury induced by various oxidants including ozone, nitrogen dioxide, amiodarone, and paraquat and to protect against bleomycin-induced lung injury in combination with niacin."1.35Protection of bleomycin-induced fibrosis and inflammation by taurine. ( Gordon, RE; Park, E; Park, SY; Schuller-Levis, G; Wang, C, 2009)
"Betaine or taurine was also found to decrease serum transaminase activities and hepatic lipid peroxidation without any change in hepatic antioxidant system in rats with hepatic fibrosis."1.32Betaine or taurine administration prevents fibrosis and lipid peroxidation induced by rat liver by ethanol plus carbon tetrachloride intoxication. ( Balkan, J; Cevikbaş, U; Erman, F; Koçak-Toker, N; Uysal, M, 2004)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (35.29)29.6817
2010's8 (47.06)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Ommati, MM1
Mobasheri, A1
Ma, Y1
Xu, D1
Tang, Z1
Manthari, RK1
Abdoli, N1
Azarpira, N1
Lu, Y1
Sadeghian, I1
Mousavifaraz, A1
Nadgaran, A1
Nikoozadeh, A1
Mazloomi, S1
Mehrabani, PS1
Rezaei, M1
Xin, H1
Mingyu, Y1
Niknahad, H1
Heidari, R1
Zhang, Y2
Zhang, H1
Hu, L1
Wei, J1
Ma, C1
Madbouly, N1
Azmy, A1
Salama, A1
El-Amir, A1
Ito, T1
Hanahata, Y1
Kine, K1
Murakami, S1
Schaffer, SW1
Chen, DQ1
Cao, G1
Chen, H2
Argyopoulos, CP1
Yu, H1
Su, W1
Chen, L1
Samuels, DC1
Zhuang, S1
Bayliss, GP1
Zhao, S1
Yu, XY1
Vaziri, ND1
Wang, M1
Liu, D1
Mao, JR1
Ma, SX1
Zhao, J1
Shang, YQ1
Kang, H1
Ye, F1
Cheng, XH1
Li, XR1
Zhang, L1
Meng, MX1
Guo, Y1
Zhao, YY1
Yang, L1
Tang, J1
Ge, D1
Sui, T1
Que, J1
Cao, X1
Ge, Y1
Schuller-Levis, G1
Gordon, RE1
Wang, C1
Park, SY1
Park, E1
Deng, X1
Liang, J1
Lin, ZX1
Wu, FS1
Zhang, YP1
Zhang, ZW1
Lee, E1
Ryu, GR1
Ko, SH1
Ahn, YB1
Yoon, KH1
Ha, H1
Song, KH1
Kirov, A1
Duarte, M1
Guay, J1
Karolak, M1
Yan, C1
Oxburgh, L1
Prudovsky, I1
Yeh, CY1
Chung-Davidson, YW1
Wang, H1
Li, K1
Li, W1
Matsushita, K2
Mizushima, T2
Shirahige, A2
Tanioka, H2
Sawa, K2
Ochi, K2
Tanimoto, M2
Koide, N2
Erman, F1
Balkan, J1
Cevikbaş, U1
Koçak-Toker, N1
Uysal, M1
Mas, MR1
Isik, AT1
Yamanel, L1
Inal, V1
Tasci, I1
Deveci, S1
Mas, N1
Comert, B1
Akay, C1
Ichimura, M1
Shinji, T1
Cruz, CI1
Ruiz-Torres, P1
del Moral, RG1
Rodríguez-Puyol, M1
Rodríguez-Puyol, D1
Sato, S1
Yamate, J1
Saito, T1
Hosokawa, T1
Saito, S1
Kurasaki, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease[NCT05719714]Phase 1/Phase 260 participants (Anticipated)Interventional2023-11-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

17 other studies available for taurine and Cirrhosis

ArticleYear
Taurine mitigates the development of pulmonary inflammation, oxidative stress, and histopathological alterations in a rat model of bile duct ligation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2022, Volume: 395, Issue:12

    Topics: Animals; Antioxidants; Bile Ducts; Cholestasis; Fibrosis; Inflammation; Ligation; Liver; Liver Cirrh

2022
lncRNA TUG1 regulates hyperuricemia-induced renal fibrosis in a rat model.
    Acta biochimica et biophysica Sinica, 2022, Sep-25, Volume: 54, Issue:9

    Topics: Animals; Cell Proliferation; Fibrosis; Hyperuricemia; Kidney Diseases; MicroRNAs; Rats; RNA, Long No

2022
The nephroprotective properties of taurine-amikacin treatment in rats are mediated through HSP25 and TLR-4 regulation.
    The Journal of antibiotics, 2021, Volume: 74, Issue:9

    Topics: Amikacin; Animals; Anti-Bacterial Agents; Apoptosis; Blood Urea Nitrogen; Creatinine; Dose-Response

2021
Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:10

    Topics: Actins; Aging; Animals; Connective Tissue Growth Factor; Fibrosis; Galectin 3; Gene Expression; Hear

2018
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
    Nature communications, 2019, 04-01, Volume: 10, Issue:1

    Topics: Acetylcarnitine; Animals; Canavanine; Carnitine; Case-Control Studies; Disease Models, Animal; Disea

2019
Taurine Reduced Epidural Fibrosis in Rat Models after Laminectomy via Downregulating EGR1.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:6

    Topics: Animals; Cells, Cultured; Down-Regulation; Early Growth Response Protein 1; Epidural Space; Fibrobla

2016
Protection of bleomycin-induced fibrosis and inflammation by taurine.
    International immunopharmacology, 2009, Volume: 9, Issue:7-8

    Topics: Animals; Bleomycin; Cell Movement; Chemotaxis; Chromatography, High Pressure Liquid; Cytoprotection;

2009
Natural taurine promotes apoptosis of human hepatic stellate cells in proteomics analysis.
    World journal of gastroenterology, 2010, Apr-21, Volume: 16, Issue:15

    Topics: Apoptosis; Blotting, Western; Electrophoresis, Gel, Two-Dimensional; Fibrosis; Flow Cytometry; Gene

2010
Antioxidant treatment may protect pancreatic beta cells through the attenuation of islet fibrosis in an animal model of type 2 diabetes.
    Biochemical and biophysical research communications, 2011, Oct-22, Volume: 414, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Cyclic N-Oxides; Cytoprotection; Diabetes Mellitus,

2011
Transgenic expression of nonclassically secreted FGF suppresses kidney repair.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Animals; Base Sequence; Cell Enlargement; DNA Primers; Endothelial Cells; Fibroblast Growth Factor 1

2012
Intestinal synthesis and secretion of bile salts as an adaptation to developmental biliary atresia in the sea lamprey.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Jul-10, Volume: 109, Issue:28

    Topics: Animals; Bile Acids and Salts; Biliary Atresia; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Chroma

2012
Effect of taurine on acinar cell apoptosis and pancreatic fibrosis in dibutyltin dichloride-induced chronic pancreatitis.
    Acta medica Okayama, 2012, Volume: 66, Issue:4

    Topics: Acinar Cells; Animals; Apoptosis; Blotting, Western; Cell Culture Techniques; Fibrosis; Male; Organo

2012
Betaine or taurine administration prevents fibrosis and lipid peroxidation induced by rat liver by ethanol plus carbon tetrachloride intoxication.
    Amino acids, 2004, Volume: 27, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; beta-Alanine; Betaine; Carbon Tetrachlor

2004
Antioxidant treatment with taurine ameliorates chronic pancreatitis in an experimental rat model.
    Pancreas, 2006, Volume: 33, Issue:1

    Topics: Animals; Antioxidants; Body Weight; Disease Models, Animal; Fibrosis; Glutathione Peroxidase; Male;

2006
Oral administration of taurine improves experimental pancreatic fibrosis.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:2

    Topics: Administration, Oral; Animals; Collagen Type I; Diet; Enzyme Inhibitors; Fibrosis; Interleukin-2; In

2008
Age-related progressive renal fibrosis in rats and its prevention with ACE inhibitors and taurine.
    American journal of physiology. Renal physiology, 2000, Volume: 278, Issue:1

    Topics: Age Factors; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Extracellul

2000
Protective effect of taurine against renal interstitial fibrosis of rats induced by cisplatin.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 365, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cisplatin; Fibrosis; Immunohistochemistry; Kidney; Macro

2002