taurine has been researched along with Chemical and Drug Induced Liver Injury in 50 studies
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Taurine pretreatment also reduced the elevated expression levels of LPS‑induced cyclooxygenase‑2, nuclear factor κB and extracellular regulated protein kinase." | 5.46 | Taurine alleviates lipopolysaccharide‑induced liver injury by anti‑inflammation and antioxidants in rats. ( Li, F; Liu, Y; Wang, Y; Wu, J; Yu, H; Zhang, L, 2017) |
| " Moreover, currently used chemotherapeutics have severe toxic side effects." | 5.38 | The antineoplastic antibiotic taurolidine promotes lung and liver metastasis in two syngeneic osteosarcoma mouse models and exhibits severe liver toxicity. ( Arlt, MJ; Banke, IJ; Bertz, J; Born, W; Ehrensperger, F; Fuchs, B; Puskas, GJ; Rentsch, KM; Steinmann, P; Walters, DK, 2012) |
| "1." | 2.39 | The in vivo and in vitro protective properties of taurine. ( Seabra, V; Timbrell, JA; Waterfield, CJ, 1995) |
| "Taurine (Tau) has been used against hepatotoxicity caused by different environmental toxins." | 1.91 | Hepatoprotective Effects of Taurine Against Cadmium-Induced Liver Injury in Female Mice. ( Cui, S; Ma, K; Qiu, G; Zheng, J; Zhou, Y, 2023) |
| "Isotretinoin is a systemic retinoid that has been approved for therapy of acne vulgaris since 1982." | 1.72 | The hepatoprotective effects of taurine against oxidative stress induced by isotretinoin in rats. ( Gholamzadeh, F; Hosseini, R; Taziki, S, 2022) |
| " Combining the results of biochemical indexes and metabolomics analysis, both raw BR and VPBR showed toxic effect on rats, whereas vinegar processing reduced its toxicity." | 1.72 | [Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics]. ( Li, ZY; Qin, XM; Sun, HM; Zhang, T, 2022) |
| "Hemorrhage was present in the kidneys of all groups." | 1.48 | Energy drink and alcohol combination leads to kidney and liver alterations in rats. ( Altknecht, L; Arbo, MD; Cestonaro, LV; Costa-Valle, MT; Cunha, CD; Dallegrave, E; Fão, N; Garcia, SC; Göethel, G; Leal, MB; Tonieto, BD, 2018) |
| "Taurine pretreatment also reduced the elevated expression levels of LPS‑induced cyclooxygenase‑2, nuclear factor κB and extracellular regulated protein kinase." | 1.46 | Taurine alleviates lipopolysaccharide‑induced liver injury by anti‑inflammation and antioxidants in rats. ( Li, F; Liu, Y; Wang, Y; Wu, J; Yu, H; Zhang, L, 2017) |
| "5-Fluorouracil (5-FU) is a pyrimidine analog widely used for the treatment of various cancers, but often causes hepatic damage in clinical practice." | 1.43 | Taurine as a protective agent for 5-fluorouracil-induced hepatic damage related to oxidative stress. ( Fukuno, S; Konishi, H; Nagai, K; Suzuki, H; Yoshida, S, 2016) |
| " Moreover, currently used chemotherapeutics have severe toxic side effects." | 1.38 | The antineoplastic antibiotic taurolidine promotes lung and liver metastasis in two syngeneic osteosarcoma mouse models and exhibits severe liver toxicity. ( Arlt, MJ; Banke, IJ; Bertz, J; Born, W; Ehrensperger, F; Fuchs, B; Puskas, GJ; Rentsch, KM; Steinmann, P; Walters, DK, 2012) |
| "Acetaminophen (APAP) is a commonly used and effective analgesic and antipyretic agent." | 1.38 | Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients. ( Hashimoto, T; Kobayashi, A; Kondo, K; Kuno, H; Shoda, T; Sugai, S; Suzuki, Y; Takahashi, A; Toyoda, K; Yamada, N, 2012) |
| " Since S-adenosylmethionine (SAMe) is the primary source of the sulfur atom in glutathione, UPLC/MS and NMR were used to evaluate metabolites involved with the transulfuration pathway in urine samples collected during studies of eight liver toxic compounds in Sprague-Dawley rats." | 1.35 | Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies. ( Beger, RD; Chen, M; Dragan, Y; Holland, RD; Schnackenberg, LK; Sun, J; Tong, W; Welsh, W, 2009) |
| "Hepatotoxicity was revealed by traditional toxicity evaluation in rats treated with higher dosage and longer treatment of INH." | 1.34 | [Metabonomics profile of urine from rats administrated with different treatment period of isoniazid]. ( Liao, Y; Peng, SQ; Yan, XZ; Zhang, LS, 2007) |
| "Taurine or betaine pretreatment in lipopolysaccharide-injected rats caused significant decreases in plasma transaminase activities and hepatic malondialdehyde and DC levels, and significant increases in glutathione and alpha-tocopherol (not betaine) levels without changing ascorbic acid levels and SOD and glutathione peroxidase activities in the liver." | 1.33 | The effect of taurine or betaine pretreatment on hepatotoxicity and prooxidant status induced by lipopolysaccharide treatment in the liver of rats. ( Aykaç-Toker, G; Balkan, J; Doğru-Abbasoğlu, S; Parldar, FH; Uysal, M, 2005) |
| "As part of a wider metabonomic investigation into the early detection and discrimination of site-specific hepatotoxicity, male Sprague-Dawley rats were dosed with the model hepatotoxins allyl formate, ethionine and alpha-naphthylisothiocyanate (ANIT)." | 1.32 | An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria. ( Charuel, C; Clayton, TA; Everett, JR; Hanton, G; Le Net, JL; Lindon, JC; Nicholson, JK; Provost, JP, 2003) |
| " The contributions of the metabolites to the separation of control from dosed liver tissues varied depending on the type of spectral editing method used." | 1.32 | Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues. ( Antti, H; Beckonert, O; Bollard, ME; Ebbels, TM; Holmes, E; Keun, H; Lindon, JC; Nicholson, JK; Tang, H; Wang, Y, 2003) |
| "Taurine (200 mg/kg) was given 12 h before, at the time of, and 1 or 2 h after acetaminophen injection." | 1.31 | Role of taurine in preventing acetaminophen-induced hepatic injury in the rat. ( Bouchier-Hayes, D; Kay, E; Redmond, HP; Wang, JH; Waters, E; Wu, QD, 2001) |
| " Light microscopic examination of sections of the liver taken 5 weeks after dosing of CCl4 showed hydropic degeneration of hepatocytes around the central veins and lipid vacuolation in mid-zonal and some periportal hepatocytes." | 1.29 | Abnormal expressions of hepatocellular proteins and extracellular matrix in CCL4-induced liver injury in rats. ( Chen, L; Yang, X; Zhong, X; Zhou, J, 1996) |
| " The peak elevation in urinary taurine occurred within the first 48 h after dosing but there was still significant taurinuria 72 and 96 h after the intermediate dose (1 ml." | 1.28 | Taurine, a possible urinary marker of liver damage: a study of taurine excretion in carbon tetrachloride-treated rats. ( Scales, MD; Timbrell, JA; Turton, JA; Waterfield, CJ, 1991) |
| "The urinary excretion of taurine by rats after dosing with various hepatotoxins has been investigated by 1H NMR spectroscopy." | 1.28 | Hepatotoxin-induced hypertaurinuria: a proton NMR study. ( Elcombe, C; Nicholson, JK; Sanins, SM; Timbrell, JA, 1990) |
| "Hypertransaminasemia is a frequent side effect during chenodeoxycholic administration for gallstone dissolution." | 1.27 | Bile acid-induced liver toxicity: relation to the hydrophobic-hydrophilic balance of bile acids. ( Alvaro, D; Angelico, M; Attili, AF; Cantafora, A; Capocaccia, L, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (8.00) | 18.7374 |
| 1990's | 4 (8.00) | 18.2507 |
| 2000's | 16 (32.00) | 29.6817 |
| 2010's | 20 (40.00) | 24.3611 |
| 2020's | 6 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, J | 1 |
| Qiu, G | 1 |
| Zhou, Y | 3 |
| Ma, K | 1 |
| Cui, S | 1 |
| Beigi, T | 1 |
| Safi, A | 1 |
| Satvati, M | 1 |
| Kalantari-Hesari, A | 1 |
| Ahmadi, R | 1 |
| Meshkibaf, MH | 1 |
| Zhao, DD | 1 |
| Wang, JJ | 1 |
| Fan, JJ | 1 |
| Fu, Y | 1 |
| Ma, YD | 1 |
| Li, C | 2 |
| Wu, GF | 1 |
| Liu, M | 1 |
| Lin, SM | 1 |
| Hu, JM | 1 |
| Taziki, S | 1 |
| Gholamzadeh, F | 1 |
| Hosseini, R | 1 |
| Sun, HM | 2 |
| Zhang, T | 2 |
| Li, ZY | 2 |
| Qin, XM | 2 |
| Khodayar, MJ | 1 |
| Kalantari, H | 1 |
| Khorsandi, L | 1 |
| Ahangar, N | 1 |
| Samimi, A | 1 |
| Alidadi, H | 1 |
| Liu, Y | 1 |
| Li, F | 1 |
| Zhang, L | 1 |
| Wu, J | 1 |
| Wang, Y | 3 |
| Yu, H | 1 |
| Fukuno, S | 2 |
| Nagai, K | 2 |
| Yoshida, S | 1 |
| Suzuki, H | 1 |
| Konishi, H | 2 |
| Costa-Valle, MT | 1 |
| Tonieto, BD | 1 |
| Altknecht, L | 1 |
| Cunha, CD | 1 |
| Fão, N | 1 |
| Cestonaro, LV | 1 |
| Göethel, G | 1 |
| Garcia, SC | 1 |
| Leal, MB | 1 |
| Dallegrave, E | 1 |
| Arbo, MD | 1 |
| Kalaz, EB | 1 |
| Çoban, J | 1 |
| Aydın, AF | 1 |
| Doğan-Ekici, I | 1 |
| Doğru-Abbasoğlu, S | 4 |
| Öztezcan, S | 1 |
| Uysal, M | 4 |
| Sukhanov, DS | 1 |
| Vinogradova, TI | 1 |
| Zabolotnykh, NV | 1 |
| Okovityĭ, SV | 1 |
| Vasil'eva, SN | 1 |
| Vitovskaia, ML | 1 |
| Cao, W | 1 |
| Li, Y | 1 |
| Zhang, X | 1 |
| He, M | 1 |
| Zang, N | 1 |
| Liao, M | 1 |
| Başaran-Küçükgergin, C | 1 |
| Bingül, I | 1 |
| Tekkeşin, MS | 1 |
| Olgaç, V | 1 |
| Lin, CJ | 1 |
| Chiu, CC | 1 |
| Chen, YC | 1 |
| Chen, ML | 1 |
| Hsu, TC | 1 |
| Tzang, BS | 1 |
| Mei, X | 1 |
| Yuan, J | 1 |
| Lu, W | 1 |
| Li, B | 1 |
| Xu, D | 1 |
| Oda, A | 1 |
| Li, P | 1 |
| Tan, YM | 1 |
| Lam, SH | 1 |
| Chan, EC | 1 |
| Gong, Z | 1 |
| Liao, Y | 2 |
| Peng, SQ | 1 |
| Yan, XZ | 1 |
| Zhang, LS | 1 |
| Schnackenberg, LK | 1 |
| Chen, M | 1 |
| Sun, J | 1 |
| Holland, RD | 1 |
| Dragan, Y | 1 |
| Tong, W | 1 |
| Welsh, W | 1 |
| Beger, RD | 1 |
| Ozden, S | 1 |
| Catalgol, B | 1 |
| Gezginci-Oktayoglu, S | 1 |
| Arda-Pirincci, P | 1 |
| Bolkent, S | 1 |
| Alpertunga, B | 1 |
| Shimada, T | 1 |
| Nakanishi, T | 1 |
| Toyama, A | 1 |
| Yamauchi, S | 1 |
| Kanzaki, A | 1 |
| Fujiwake, H | 1 |
| Sato, TA | 1 |
| Ikegawa, M | 1 |
| Acharya, M | 1 |
| Lau-Cam, CA | 1 |
| Gentile, CL | 1 |
| Nivala, AM | 1 |
| Gonzales, JC | 1 |
| Pfaffenbach, KT | 1 |
| Wang, D | 1 |
| Wei, Y | 1 |
| Jiang, H | 1 |
| Orlicky, DJ | 1 |
| Petersen, DR | 1 |
| Pagliassotti, MJ | 1 |
| Maclean, KN | 1 |
| Arlt, MJ | 2 |
| Walters, DK | 1 |
| Banke, IJ | 1 |
| Steinmann, P | 1 |
| Puskas, GJ | 1 |
| Bertz, J | 1 |
| Rentsch, KM | 1 |
| Ehrensperger, F | 1 |
| Born, W | 2 |
| Fuchs, B | 2 |
| Braumann, C | 2 |
| Pfirrmann, RW | 1 |
| Das, J | 1 |
| Roy, A | 1 |
| Sil, PC | 1 |
| Kondo, K | 1 |
| Yamada, N | 1 |
| Suzuki, Y | 1 |
| Toyoda, K | 1 |
| Hashimoto, T | 1 |
| Takahashi, A | 1 |
| Kobayashi, A | 1 |
| Shoda, T | 1 |
| Kuno, H | 1 |
| Sugai, S | 1 |
| Xu, ZW | 1 |
| Li, YS | 1 |
| Clayton, TA | 2 |
| Lindon, JC | 3 |
| Everett, JR | 2 |
| Charuel, C | 2 |
| Hanton, G | 2 |
| Le Net, JL | 2 |
| Provost, JP | 2 |
| Nicholson, JK | 4 |
| Bollard, ME | 1 |
| Keun, H | 1 |
| Antti, H | 1 |
| Beckonert, O | 1 |
| Ebbels, TM | 1 |
| Holmes, E | 1 |
| Tang, H | 3 |
| Hagar, HH | 1 |
| Miyata, M | 1 |
| Tozawa, A | 1 |
| Otsuka, H | 1 |
| Nakamura, T | 1 |
| Nagata, K | 1 |
| Gonzalez, FJ | 1 |
| Yamazoe, Y | 1 |
| Pushpakiran, G | 1 |
| Mahalakshmi, K | 1 |
| Anuradha, CV | 1 |
| Kim, SK | 1 |
| Kim, YC | 1 |
| Stuhldreier, B | 1 |
| Bobrich, E | 1 |
| Menenakos, C | 1 |
| Rogalla, S | 1 |
| Jacobi, CA | 1 |
| Balkan, J | 2 |
| Parldar, FH | 1 |
| Aykaç-Toker, G | 2 |
| Zwingmann, C | 1 |
| Bilodeau, M | 1 |
| Yap, IK | 1 |
| Lu, X | 1 |
| Lu, C | 1 |
| Li, G | 1 |
| Jin, Y | 1 |
| Timbrell, JA | 3 |
| Seabra, V | 1 |
| Waterfield, CJ | 2 |
| Zhou, J | 2 |
| Zhong, X | 1 |
| Chen, L | 1 |
| Yang, X | 1 |
| Kanbağli, O | 1 |
| Cevikbaş, U | 1 |
| Waters, E | 1 |
| Wang, JH | 1 |
| Redmond, HP | 1 |
| Wu, QD | 1 |
| Kay, E | 1 |
| Bouchier-Hayes, D | 1 |
| Turton, JA | 1 |
| Scales, MD | 1 |
| Sanins, SM | 1 |
| Elcombe, C | 1 |
| Attili, AF | 1 |
| Angelico, M | 1 |
| Cantafora, A | 1 |
| Alvaro, D | 1 |
| Capocaccia, L | 1 |
| Karasawa, T | 1 |
| Onishi, K | 1 |
| Nishimura, K | 1 |
| Upson, DW | 1 |
| Gronwall, RR | 1 |
| Cornelius, CE | 1 |
| Di Rosa, M | 1 |
3 reviews available for taurine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Mechanism of the protective action of taurine in toxin and drug induced organ pathophysiology and diabetic complications: a review.
Topics: Animals; Antioxidants; Arsenic; Blood Pressure; Cadmium; Calcium; Chemical and Drug Induced Liver In | 2012 |
Pathogenesis and treatment of parenteral nutrition-associated liver disease.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline Deficiency; Enteral Nutrition; Fat Emulsion | 2012 |
The in vivo and in vitro protective properties of taurine.
Topics: Animals; Chemical and Drug Induced Liver Injury; Humans; Taurine | 1995 |
47 other studies available for taurine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Hepatoprotective Effects of Taurine Against Cadmium-Induced Liver Injury in Female Mice.
Topics: Animals; Antioxidants; Apoptosis; Body Weight; Cadmium; Chemical and Drug Induced Liver Injury; Chem | 2023 |
Protective role of ellagic acid and taurine against fluoxetine induced hepatotoxic effects on biochemical and oxidative stress parameters, histopathological changes, and gene expressions of IL-1β, NF-κB, and TNF-α in male Wistar rats.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Ellagic Acid; Fluoxetine; Male; NF-ka | 2022 |
Taurine Prevents LPS-Induced Liver Injury in Weaned Piglets.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Chemical and Drug Induced Liver Injury; C | 2022 |
The hepatoprotective effects of taurine against oxidative stress induced by isotretinoin in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; | 2022 |
[Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics].
Topics: Acetic Acid; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Me | 2022 |
[Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics].
Topics: Acetic Acid; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Me | 2022 |
[Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics].
Topics: Acetic Acid; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Me | 2022 |
[Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics].
Topics: Acetic Acid; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Me | 2022 |
Taurine attenuates valproic acid-induced hepatotoxicity via modulation of RIPK1/RIPK3/MLKL-mediated necroptosis signaling in mice.
Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Imidazoles; Indoles; Male; Mice; Necropt | 2021 |
Taurine alleviates lipopolysaccharide‑induced liver injury by anti‑inflammation and antioxidants in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced | 2017 |
Taurine as a protective agent for 5-fluorouracil-induced hepatic damage related to oxidative stress.
Topics: Animals; Antimetabolites, Antineoplastic; Chemical and Drug Induced Liver Injury; Dose-Response Rela | 2016 |
Energy drink and alcohol combination leads to kidney and liver alterations in rats.
Topics: Alcoholic Beverages; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Chemica | 2018 |
Carnosine and taurine treatments decreased oxidative stress and tissue damage induced by D-galactose in rat liver.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carnosine; Chemical and Dr | 2014 |
[Pharmacological activity of runihol and S-adenosyl-L-methionine in rats with experimental liver damage by reserve antituberculosis drugs].
Topics: Aminosalicylic Acid; Animals; Animals, Outbred Strains; Antitubercular Agents; Bilirubin; Chemical a | 2013 |
iTRAQ-based proteomic analysis of combination therapy with taurine, epigallocatechin gallate, and genistein on carbon tetrachloride-induced liver fibrosis in rats.
Topics: Animals; Antioxidants; Blotting, Western; Catechin; Chemical and Drug Induced Liver Injury; Chromato | 2015 |
Effects of carnosine, taurine, and betaine pretreatments on diethylnitrosamine-induced oxidative stress and tissue injury in rat liver.
Topics: Animals; Antioxidants; Betaine; Biomarkers; Carcinogens, Environmental; Carnosine; Chemical and Drug | 2016 |
Taurine Attenuates Hepatic Inflammation in Chronic Alcohol-Fed Rats Through Inhibition of TLR4/MyD88 Signaling.
Topics: Animals; C-Reactive Protein; Chemical and Drug Induced Liver Injury; Ethanol; Inflammation; Inflamma | 2015 |
Taurine zinc solid dispersions attenuate doxorubicin-induced hepatotoxicity and cardiotoxicity in rats.
Topics: Administration, Oral; Alanine Transaminase; Animals; Anthracyclines; Antibiotics, Antineoplastic; An | 2015 |
Protective effects of taurine on doxorubicin-induced acute hepatotoxicity through suppression of oxidative stress and apoptotic responses.
Topics: Alanine Transaminase; Animals; Antibiotics, Antineoplastic; Apoptosis; Aspartate Aminotransferases; | 2016 |
Metabolomic Characterizations of Liver Injury Caused by Acute Arsenic Toxicity in Zebrafish.
Topics: Alanine Transaminase; Animals; Arsenic; Bile Acids and Salts; Bilirubin; Biomarkers; Chemical and Dr | 2016 |
[Metabonomics profile of urine from rats administrated with different treatment period of isoniazid].
Topics: Animals; Antitubercular Agents; Biomarkers; Chemical and Drug Induced Liver Injury; Citric Acid; Cit | 2007 |
Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies.
Topics: Animals; Chemical and Drug Induced Liver Injury; Comet Assay; Creatine; Drug-Related Side Effects an | 2009 |
Methiocarb-induced oxidative damage following subacute exposure and the protective effects of vitamin E and taurine in rats.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Glutathione; Insecticides; Kidney Dis | 2009 |
Potential implications for monitoring serum bile acid profiles in circulation with serum proteome for carbon tetrachloride-induced liver injury/regeneration model in mice.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Bile Acids and Sal | 2010 |
Comparison of the protective actions of N-acetylcysteine, hypotaurine and taurine against acetaminophen-induced hepatotoxicity in the rat.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug In | 2010 |
Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease.
Topics: Animals; Cell Death; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Diet; Endoplasmic Ret | 2011 |
The antineoplastic antibiotic taurolidine promotes lung and liver metastasis in two syngeneic osteosarcoma mouse models and exhibits severe liver toxicity.
Topics: Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Female | 2012 |
Taurolidine: Mode of administration in mouse tumor models.
Topics: Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Female | 2012 |
Taurolidine: mode of administration in mouse tumor models.
Topics: Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Female | 2012 |
Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antipyretics; Blood Glucose; | 2012 |
An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Cre | 2003 |
Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues.
Topics: Alanine; Animals; Chemical and Drug Induced Liver Injury; Choline; Glucose; Glycogen; Hydrazines; Li | 2003 |
The protective effect of taurine against cyclosporine A-induced oxidative stress and hepatotoxicity in rats.
Topics: Administration, Oral; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cyclosporine; D | 2004 |
Role of farnesoid X receptor in the enhancement of canalicular bile acid output and excretion of unconjugated bile acids: a mechanism for protection against cholic acid-induced liver toxicity.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile; Bile Acids | 2005 |
Protective effects of taurine on glutathione and glutathione-dependent enzymes in ethanol-fed rats.
Topics: Animals; Bilirubin; Biomarkers; Body Weight; Central Nervous System Depressants; Chemical and Drug I | 2004 |
Effects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice.
Topics: Amino Acids, Sulfur; Animals; Betaine; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; | 2005 |
High doses of taurolidine inhibit advanced intraperitoneal tumor growth in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biopsy; Cell Division; Cell Line, Tumor; Chemical an | 2005 |
The effect of taurine or betaine pretreatment on hepatotoxicity and prooxidant status induced by lipopolysaccharide treatment in the liver of rats.
Topics: Animals; Antioxidants; Betaine; Chemical and Drug Induced Liver Injury; Lipopolysaccharides; Liver D | 2005 |
Metabolic insights into the hepatoprotective role of N-acetylcysteine in mouse liver.
Topics: Acetylcysteine; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Citric Acid Cycle; Cy | 2006 |
An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate.
Topics: Animals; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Creatine; Formic Acid Este | 2006 |
Selection of agents for prevention of cisplatin-induced hepatotoxicity.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antineoplastic Agents; Antioxidants; Chemical and Dru | 2008 |
Abnormal expressions of hepatocellular proteins and extracellular matrix in CCL4-induced liver injury in rats.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Extracellular Matr | 1996 |
The protective effect of taurine against thioacetamide hepatotoxicity of rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; | 2001 |
Role of taurine in preventing acetaminophen-induced hepatic injury in the rat.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Narcotic; Animals; Apopto | 2001 |
Taurine, a possible urinary marker of liver damage: a study of taurine excretion in carbon tetrachloride-treated rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Chemic | 1991 |
Hepatotoxin-induced hypertaurinuria: a proton NMR study.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Car | 1990 |
Bile acid-induced liver toxicity: relation to the hydrophobic-hydrophilic balance of bile acids.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Acids and Sal | 1986 |
Effect of sodium taurine N-carbodithioate on acute experimental hepatic injury induced in rats by carbon tetrachloride.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1970 |
Maximal hepatic excretion of bilirubin in sheep.
Topics: Animals; Ataxia; Bilirubin; Chemical and Drug Induced Liver Injury; Female; Liver; Sheep; Spectropho | 1970 |
[Blood ammonia antagonistic and hepatoprotective effect of a combination of arginine, taurine and vitamin B6 pyrrolidon-carboxylate].
Topics: Ammonia; Animals; Arginine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; | 1967 |