taurine has been researched along with Brain Ischemia in 81 studies
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Taurine has neuroinhibitory properties and may also have potential for neuroprotection in cerebral ischemia." | 8.82 | The role of taurine in cerebral ischemia: studies in transient forebrain ischemia and embolic focal ischemia in rodents. ( Shuaib, A, 2003) |
| "Our data demonstrate the dose-dependent neuroprotection of taurine against transient focal cerebral ischemia, and suggest that one of protective mechanisms of taurine against ischemia may be blocking the m-calpain and caspase-3-mediated apoptotic cell death pathways." | 7.74 | Neuroprotective mechanism of taurine due to up-regulating calpastatin and down-regulating calpain and caspase-3 during focal cerebral ischemia. ( Sun, M; Xu, C, 2008) |
| "The releases of endogenous glutamate, aspartate, GABA and taurine from hippocampal slices from 7-day-, 3-, 12-, and 18-month-old mice were investigated under cell-damaging conditions using a superfusion system." | 7.70 | Release of endogenous glutamate, aspartate, GABA, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions. ( Oja, SS; Saransaari, P, 1998) |
| "This study investigates the effects of acamprosate, a glutamatergic modulator, and the lipid peroxidation inhibitor U-101033E on neurological outcome following incomplete cerebral ischemia and reperfusion in rats." | 7.70 | [The neuroprotective effect of the glutamate antagonist acamprosate following experimental cerebral ischemia. A study with the lipid peroxidase inhibitor u-101033e]. ( Engelhard, K; Kochs, E; Lu, H; Möllenberg, O; Werner, C; Zieglgänsberger, W, 2000) |
| "Taurine is an inhibitory neurotransmitter and is one of the most abundant amino acids present in the mammalian nervous system." | 5.39 | The mechanism of taurine protection against endoplasmic reticulum stress in an animal stroke model of cerebral artery occlusion and stroke-related conditions in primary neuronal cell culture. ( Chen, PC; Gharibani, PM; Ma, Z; Menzie, J; Modi, J; Pan, C; Prentice, H; Tao, R; Wu, JY, 2013) |
| "Taurine release was partially Ca2+-dependent in all cases." | 5.30 | Enhanced taurine release in cell-damaging conditions in the developing and ageing mouse hippocampus. ( Oja, SS; Saransaari, P, 1997) |
| " Taurine has neuroinhibitory properties and may also have potential for neuroprotection in cerebral ischemia." | 4.82 | The role of taurine in cerebral ischemia: studies in transient forebrain ischemia and embolic focal ischemia in rodents. ( Shuaib, A, 2003) |
| "Emerging evidence has suggested that hydrogen sulfide (H2S) may alleviate the cellular damage associated with cerebral ischemia/reperfusion (I/R) injury." | 3.85 | The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model. ( Choi, CG; Choi, Y; Ha, HK; Ham, SJ; Jeon, SB; Jung, SC; Kim, J; Kim, JK; Kim, KW; Kim, ST; Kwon, JI; Shim, WH; Sung, YS; Woo, CW; Woo, DC, 2017) |
| " Taurine is essential for the development and survival of neural cells and protects them under cell-damaging conditions." | 3.74 | Nitric oxide is involved in taurine release in the mouse brain stem under normal and ischemic conditions. ( Oja, SS; Saransaari, P, 2008) |
| "Our data demonstrate the dose-dependent neuroprotection of taurine against transient focal cerebral ischemia, and suggest that one of protective mechanisms of taurine against ischemia may be blocking the m-calpain and caspase-3-mediated apoptotic cell death pathways." | 3.74 | Neuroprotective mechanism of taurine due to up-regulating calpastatin and down-regulating calpain and caspase-3 during focal cerebral ischemia. ( Sun, M; Xu, C, 2008) |
| "The effect of taurine on gastric hemorrhage and mucosal erosion in the brain ischemia (BI) is unknown." | 3.73 | Effect of taurine on gastric oxidative stress and hemorrhagic erosion in brain ischemic rats. ( Hung, CR, 2006) |
| "The releases of endogenous glutamate, aspartate, GABA and taurine from hippocampal slices from 7-day-, 3-, 12-, and 18-month-old mice were investigated under cell-damaging conditions using a superfusion system." | 3.70 | Release of endogenous glutamate, aspartate, GABA, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions. ( Oja, SS; Saransaari, P, 1998) |
| " Concentrations of extracellular amino acids (glutamate, aspartate, gamma-aminobutyric acid (GABA) and taurine) and regional blood flow in the striatum of spontaneously hypertensive rats (SHRs) were monitored during cerebral ischemia elicited by bilateral carotid artery occlusion for 40 min and recirculation." | 3.70 | Modulation of ischemia-evoked release of excitatory and inhibitory amino acids by adenosine A1 receptor agonist. ( Fujishima, M; Goda, H; Ibayashi, S; Nakane, H; Ooboshi, H; Sadoshima, S, 1998) |
| "This study investigates the effects of acamprosate, a glutamatergic modulator, and the lipid peroxidation inhibitor U-101033E on neurological outcome following incomplete cerebral ischemia and reperfusion in rats." | 3.70 | [The neuroprotective effect of the glutamate antagonist acamprosate following experimental cerebral ischemia. A study with the lipid peroxidase inhibitor u-101033e]. ( Engelhard, K; Kochs, E; Lu, H; Möllenberg, O; Werner, C; Zieglgänsberger, W, 2000) |
| "To investigate global cerebral ischemia-induced alterations in the levels of glutamate, aspartate, gamma-aminobutyric acid (GABA), glutamine, glycine, and taurine from hippocampus, striatum, and cerebral cortex in gerbils." | 3.70 | Alterations of amino acid levels from striatum, hippocampus, and cerebral cortex induced by global cerebral ischemia in gerbil. ( Hu, G; Rao, MR; Tang, XC; Wang, H, 2000) |
| "Using high-performance liquid chromatography, we determined the glutamate, aspartate, taurine, and glycine concentrations in the plasma and cerebrospinal fluid (CSF) of 128 patients with ischemic cerebral infarction confirmed by CT and 43 control subjects." | 3.69 | Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke. ( Castillo, J; Dávalos, A; Naveiro, J; Noya, M, 1996) |
| "In this study, we investigated the effects of electroacupuncture (EA) on extracellular levels of amino acid neurotransmitters (glutamate, aspartate, and taurine) in striatum and cerebral infarction dimensions in rats subjected to transient focal cerebral ischemia induced by 2 hours of middle cerebral artery (MCA) occlusion." | 3.69 | Effects of electroacupuncture on extracellular contents of amino acid neurotransmitters in rat striatum following transient focal cerebral ischemia. ( Cheng, J; Zhao, P, 1997) |
| "The extracellular concentrations of aspartate, glutamate, glutamine, taurine and gamma-aminobutyric acid in the hippocampus were determined during and after forebrain ischemia (4-vessel model) in the unanaesthetized rat." | 3.68 | Concomitant increases in the extracellular concentrations of excitatory and inhibitory amino acids in the rat hippocampus during forebrain ischemia. ( Boulu, RG; Callebert, J; Lekieffre, D; Plotkine, M, 1992) |
| "Mice were exposed to cerebral ischemia, treated with intraperitoneal injections of acamprosate or saline (controls), and allowed to survive until 3 months." | 1.42 | The indirect NMDAR antagonist acamprosate induces postischemic neurologic recovery associated with sustained neuroprotection and neuroregeneration. ( Bähr, M; Doeppner, TR; Hermann, DM; Kaltwasser, B; Kilic, E; Pehlke, JR; Schlechter, J, 2015) |
| "Those that developed cerebral ischemia after MCAO were randomized to receive propylene glycol salt water and ligustrazine respectively." | 1.40 | Effect of ligustrazine on levels of amino acid neurotransmitters in rat striatum after cerebral ischemia-reperfusion injury. ( Bie, XD; Ge, LJ; Han, J; Wan, HT; Yang, JH; Zhang, YY, 2014) |
| "Taurine is an inhibitory neurotransmitter and is one of the most abundant amino acids present in the mammalian nervous system." | 1.39 | The mechanism of taurine protection against endoplasmic reticulum stress in an animal stroke model of cerebral artery occlusion and stroke-related conditions in primary neuronal cell culture. ( Chen, PC; Gharibani, PM; Ma, Z; Menzie, J; Modi, J; Pan, C; Prentice, H; Tao, R; Wu, JY, 2013) |
| "Taurine release was greatly enhanced under these cell-damaging conditions, the only exception being the presence of free radicals in both age groups." | 1.34 | Taurine release in mouse brain stem slices under cell-damaging conditions. ( Oja, SS; Saransaari, P, 2007) |
| " Agonists of the glycine recognition site of NMDA receptors (D-serine and D-alanine) did not have any toxic effect in hippocampal cultures, whereas competitive blockade of the glycine site by 7-chlorokynurenic acid was neuroprotective." | 1.33 | Glycine-induced neurotoxicity in organotypic hippocampal slice cultures. ( Barth, A; Barth, L; Newell, DW; Nguyen, LB, 2005) |
| "We introduced intracerebral hemorrhage in each of eight anesthetized New Zealand rabbits by injecting 0." | 1.32 | Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study. ( Ali, Z; Baker, G; Guterman, LR; Hopkins, LN; Qureshi, AI; Shuaib, A; Suri, MF; Todd, K, 2003) |
| "Reversible middle cerebral artery occlusion (rMCAo) was induced in anesthetized rats using the intraluminal suture technique." | 1.32 | Volume-regulated anion channels are the predominant contributors to release of excitatory amino acids in the ischemic cortical penumbra. ( Feustel, PJ; Jin, Y; Kimelberg, HK, 2004) |
| " Compared with the model group, the concentration of Glu in the middle and large dosage groups of TGF, during the 120 min of ischemia, reduced by 38." | 1.32 | [Effects of tianma gouteng fang on transmitter amino acids in the hippocampus extracellular liquids in freely moving rats subjected to brain ischemia]. ( Du, GY; Sun, XF; Wang, DQ; Wang, W; Ye, ZG; Zhang, CY; Zhao, DZ, 2004) |
| "Taurine and glutamate were monitored by microdialysis technique during various cerebral insults: a." | 1.31 | Observations on the relationship between the extracellular changes of taurine and glutamate during cortical spreading depression, during ischemia, and within the area surrounding a thrombotic infarct. ( Kolb, J; Scheller, D; Szathmary, S; Tegtmeier, F, 2000) |
| "Taurine release was partially Ca2+-dependent in all cases." | 1.30 | Enhanced taurine release in cell-damaging conditions in the developing and ageing mouse hippocampus. ( Oja, SS; Saransaari, P, 1997) |
| "Brain ischemia was induced for 10 or 30 min by clamping the common carotid arteries in rabbits whose vertebral arteries had previously been electrocauterized." | 1.27 | Ischemia-induced shift of inhibitory and excitatory amino acids from intra- to extracellular compartments. ( Hagberg, H; Hamberger, A; Jacobson, I; Lehmann, A; Nyström, B; Sandberg, M, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (3.70) | 18.7374 |
| 1990's | 28 (34.57) | 18.2507 |
| 2000's | 36 (44.44) | 29.6817 |
| 2010's | 14 (17.28) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woo, CW | 1 |
| Kwon, JI | 1 |
| Kim, KW | 1 |
| Kim, JK | 1 |
| Jeon, SB | 1 |
| Jung, SC | 1 |
| Choi, CG | 1 |
| Kim, ST | 1 |
| Kim, J | 1 |
| Ham, SJ | 1 |
| Shim, WH | 1 |
| Sung, YS | 1 |
| Ha, HK | 1 |
| Choi, Y | 1 |
| Woo, DC | 1 |
| Wu, S | 1 |
| Yue, Y | 1 |
| Tian, H | 1 |
| Tao, L | 1 |
| Wang, Y | 1 |
| Xiang, J | 1 |
| Wang, S | 1 |
| Ding, H | 1 |
| Han, J | 1 |
| Wan, HT | 1 |
| Yang, JH | 1 |
| Zhang, YY | 1 |
| Ge, LJ | 1 |
| Bie, XD | 1 |
| Makarova, LM | 1 |
| Pogoreliy, VE | 1 |
| Novikova, NA | 1 |
| Oleynikova, ON | 1 |
| Makarova, TI | 1 |
| Doeppner, TR | 1 |
| Pehlke, JR | 1 |
| Kaltwasser, B | 1 |
| Schlechter, J | 1 |
| Kilic, E | 1 |
| Bähr, M | 1 |
| Hermann, DM | 1 |
| Zhang, Z | 1 |
| Yu, R | 1 |
| Cao, L | 1 |
| Saransaari, P | 20 |
| Oja, SS | 20 |
| Tanabe, M | 1 |
| Nitta, A | 1 |
| Ono, H | 1 |
| Sun, M | 2 |
| Gu, Y | 1 |
| Zhao, Y | 1 |
| Xu, C | 2 |
| Ricci, L | 1 |
| Valoti, M | 1 |
| Sgaragli, G | 1 |
| Frosini, M | 1 |
| Alf, MF | 1 |
| Lei, H | 1 |
| Berthet, C | 1 |
| Hirt, L | 1 |
| Gruetter, R | 1 |
| Mlynarik, V | 1 |
| Tu, J | 1 |
| A, J | 1 |
| Wang, G | 1 |
| Wen, H | 1 |
| Wang, A | 1 |
| Di, L | 1 |
| Cao, B | 1 |
| Liu, L | 1 |
| Gharibani, PM | 1 |
| Modi, J | 1 |
| Pan, C | 1 |
| Menzie, J | 1 |
| Ma, Z | 1 |
| Chen, PC | 1 |
| Tao, R | 1 |
| Prentice, H | 1 |
| Wu, JY | 1 |
| Qureshi, AI | 1 |
| Ali, Z | 1 |
| Suri, MF | 1 |
| Shuaib, A | 4 |
| Baker, G | 1 |
| Todd, K | 1 |
| Guterman, LR | 1 |
| Hopkins, LN | 1 |
| Kimelberg, HK | 3 |
| Nestor, NB | 1 |
| Feustel, PJ | 2 |
| Jin, Y | 1 |
| Miyamoto, TA | 1 |
| Miyamoto, KJ | 1 |
| Barth, A | 1 |
| Nguyen, LB | 1 |
| Barth, L | 1 |
| Newell, DW | 1 |
| Zhang, CY | 1 |
| Du, GY | 1 |
| Wang, W | 1 |
| Ye, ZG | 1 |
| Wang, DQ | 1 |
| Sun, XF | 1 |
| Zhao, DZ | 1 |
| Li, M | 1 |
| Gao, GD | 1 |
| Zheng, J | 1 |
| Sun, LZ | 1 |
| Long, C | 1 |
| Molchanova, SM | 1 |
| Sapronov, NS | 2 |
| Bul'on, VV | 1 |
| Krylova, IB | 2 |
| Gavrovskaya, LK | 2 |
| Selina, EN | 2 |
| Evdokimova, NR | 1 |
| Hung, CR | 1 |
| Zhou, F | 2 |
| Guo, J | 2 |
| Yang, R | 2 |
| Gu, J | 1 |
| Jin, H | 1 |
| Wu, G | 1 |
| Cheng, J | 3 |
| Zhao, P | 2 |
| Xia, Y | 1 |
| Bulion, VV | 1 |
| Kuznetzova, NN | 1 |
| Oda, M | 1 |
| Kure, S | 1 |
| Sugawara, T | 1 |
| Yamaguchi, S | 1 |
| Kojima, K | 1 |
| Shinka, T | 1 |
| Sato, K | 1 |
| Narisawa, A | 1 |
| Aoki, Y | 1 |
| Matsubara, Y | 1 |
| Omae, T | 1 |
| Mizoi, K | 1 |
| Kinouchi, H | 1 |
| Erecińska, M | 1 |
| Nelson, D | 1 |
| Wilson, DF | 1 |
| Silver, IA | 1 |
| Igarashi, H | 1 |
| Kwee, IL | 1 |
| Nakada, T | 1 |
| Montalbetti, L | 1 |
| Rozza, A | 1 |
| Rizzo, V | 1 |
| Favalli, L | 1 |
| Scavini, C | 1 |
| Lanza, E | 1 |
| Savoldi, F | 1 |
| Racagni, G | 1 |
| Scelsi, R | 1 |
| Stummer, W | 1 |
| Betz, AL | 1 |
| Shakui, P | 1 |
| Keep, RF | 1 |
| Igisu, H | 1 |
| Matsuoka, M | 1 |
| Iryo, Y | 1 |
| Hagberg, H | 4 |
| Thornberg, E | 1 |
| Blennow, M | 1 |
| Kjellmer, I | 2 |
| Lagercrantz, H | 1 |
| Thiringer, K | 2 |
| Hamberger, A | 2 |
| Sandberg, M | 3 |
| Puka, M | 1 |
| Lehmann, A | 2 |
| van Zijl, PC | 1 |
| Moonen, CT | 1 |
| Taguchi, T | 1 |
| Miyake, K | 1 |
| Tanonaka, K | 1 |
| Okada, M | 1 |
| Takagi, N | 1 |
| Fujimori, K | 1 |
| Takeo, S | 1 |
| Nakata, N | 1 |
| Kato, H | 1 |
| Kogure, K | 1 |
| Castillo, J | 1 |
| Dávalos, A | 1 |
| Naveiro, J | 1 |
| Noya, M | 1 |
| Kanthan, R | 1 |
| Nonaka, M | 1 |
| Yoshimine, T | 1 |
| Kohmura, E | 1 |
| Wakayama, A | 1 |
| Yamashita, T | 1 |
| Hayakawa, T | 1 |
| Mongin, AA | 1 |
| Goda, H | 1 |
| Ooboshi, H | 2 |
| Nakane, H | 1 |
| Ibayashi, S | 2 |
| Sadoshima, S | 2 |
| Fujishima, M | 2 |
| Shimizu-Sasamata, M | 1 |
| Bosque-Hamilton, P | 1 |
| Huang, PL | 1 |
| Moskowitz, MA | 1 |
| Lo, EH | 1 |
| Phillis, JW | 5 |
| Song, D | 4 |
| O'Regan, MH | 5 |
| Guyot, LL | 3 |
| Melani, A | 1 |
| Pantoni, L | 1 |
| Corsi, C | 1 |
| Bianchi, L | 1 |
| Monopoli, A | 1 |
| Bertorelli, R | 1 |
| Pepeu, G | 1 |
| Pedata, F | 1 |
| Li, PA | 1 |
| Miyashita, H | 1 |
| He, QP | 1 |
| Siesjö, BK | 1 |
| Warner, DS | 1 |
| Diaz, FG | 2 |
| Ren, J | 1 |
| Engelhard, K | 1 |
| Werner, C | 1 |
| Lu, H | 1 |
| Möllenberg, O | 1 |
| Zieglgänsberger, W | 1 |
| Kochs, E | 1 |
| Takano, K | 1 |
| Kondo, A | 1 |
| Uchimura, H | 1 |
| Scheller, D | 1 |
| Szathmary, S | 1 |
| Kolb, J | 1 |
| Tegtmeier, F | 1 |
| Uchino, S | 1 |
| Nakamura, T | 1 |
| Nakamura, K | 1 |
| Nakajima-Iijima, S | 1 |
| Mishina, M | 1 |
| Kohsaka, S | 1 |
| Kudo, Y | 1 |
| Tang, XC | 1 |
| Rao, MR | 1 |
| Hu, G | 1 |
| Wang, H | 1 |
| Lekieffre, D | 1 |
| Callebert, J | 1 |
| Plotkine, M | 1 |
| Boulu, RG | 1 |
| Lombardini, JB | 1 |
| Andiné, P | 1 |
| Orwar, O | 1 |
| Jacobson, I | 2 |
| Andersson, P | 1 |
| Thordstein, M | 1 |
| Nyström, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brain Changes in Pediatric Obstructive Sleep Apnea[NCT05368077] | 70 participants (Anticipated) | Interventional | 2022-05-14 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for taurine and Brain Ischemia
| Article | Year |
|---|---|
The role of taurine in cerebral ischemia: studies in transient forebrain ischemia and embolic focal ischemia in rodents.
Topics: Animals; Brain Ischemia; Intracranial Embolism; Prosencephalon; Rodentia; Taurine | 2003 |
Interactions of taurine and adenosine in the mouse hippocampus in normoxia and ischemia.
Topics: Adenosine; Animals; Brain Ischemia; Hippocampus; Mice; Oxygen; Taurine | 2003 |
Involvement of nitric oxide in ischemia-evoked taurine release in the mouse hippocampus.
Topics: Animals; Brain Ischemia; Cyclic GMP; Hippocampus; Mice; N-Methylaspartate; Nitric Oxide; Nitric Oxid | 2003 |
Inhibition of release of taurine and excitatory amino acids in ischemia and neuroprotection.
Topics: Animals; Brain Ischemia; Corpus Striatum; Excitatory Amino Acids; Humans; Nitric Oxide Synthase; Nit | 2004 |
Protection of the brain by carnitine.
Topics: Ammonia; Animals; Brain; Brain Ischemia; Carnitine; Energy Metabolism; Humans; Mice; Seizures; Tauri | 1995 |
Amplification of inhibitory mechanisms in cerebral ischemia: an alternative approach to neuronal protection.
Topics: Adenosine; Animals; Brain Ischemia; Calcium Channels; gamma-Aminobutyric Acid; Humans; Hypothermia, | 1997 |
Swelling-activated release of excitatory amino acids in the brain: relevance for pathophysiology.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1998 |
Taurine and neural cell damage.
Topics: Animals; Brain Ischemia; Cell Death; Humans; Mice; Neurons; Taurine | 2000 |
Review: recent studies on taurine in the central nervous system.
Topics: Aging; Alzheimer Disease; Animals; Brain Ischemia; Central Nervous System; Female; Humans; Hypoxia, | 1992 |
72 other studies available for taurine and Brain Ischemia
| Article | Year |
|---|---|
The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model.
Topics: Animals; Apoptosis; Aspartic Acid; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Humans; Hy | 2017 |
Tramiprosate protects neurons against ischemic stroke by disrupting the interaction between PSD95 and nNOS.
Topics: Animals; Apoptosis; Brain Ischemia; Disks Large Homolog 4 Protein; Intracellular Signaling Peptides | 2014 |
Effect of ligustrazine on levels of amino acid neurotransmitters in rat striatum after cerebral ischemia-reperfusion injury.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid | 2014 |
Experimental study of taurine on the cerebral dehydrogenase activity in the model of unilateral cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Carotid Artery, Common; Cell Survival; Coronary Occlusion; Disease M | 2015 |
The indirect NMDAR antagonist acamprosate induces postischemic neurologic recovery associated with sustained neuroprotection and neuroregeneration.
Topics: Acamprosate; Animals; Blood-Brain Barrier; Brain Ischemia; Calpain; Enzyme Activation; Interleukin-1 | 2015 |
Neuroprotection of taurine through inhibition of 12/15 lipoxygenase pathway in cerebral ischemia of rats.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Brain Edema; Brain Infarction; | 2017 |
Modulation of taurine release in ischemia by glutamate receptors in mouse brain stem slices.
Topics: Aging; Animals; Animals, Newborn; Brain Ischemia; Brain Stem; Cell Hypoxia; Excitatory Amino Acid Ag | 2010 |
Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.
Topics: Aging; Alanine; Animals; Aspartic Acid; Brain Ischemia; Brain Stem; Female; gamma-Aminobutyric Acid; | 2009 |
Adenosine receptor agonists affect taurine release from mouse brain stem slices in ischemia.
Topics: Adenosine; Animals; Brain Ischemia; Brain Stem; Female; Male; Mice; Phenethylamines; Purinergic P1 R | 2010 |
Neuroprotection via strychnine-sensitive glycine receptors during post-ischemic recovery of excitatory synaptic transmission in the hippocampus.
Topics: Animals; Brain Ischemia; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniqu | 2010 |
Protective functions of taurine against experimental stroke through depressing mitochondria-mediated cell death in rats.
Topics: Adenosine Triphosphate; Animals; bcl-2-Associated X Protein; bcl-X Protein; Brain Ischemia; Calpain; | 2011 |
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Brain Ischemia; gamma-Aminobutyric Acid; Glucose; Male | 2012 |
High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice.
Topics: Animals; Aspartic Acid; Brain Ischemia; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Infarct | 2012 |
[Plasma metabonomics study of ischemic cerebral apoplexy rats treated with Tongsaimai pellets].
Topics: Animals; Brain Ischemia; Drugs, Chinese Herbal; Fructose; Glyceric Acids; Hydroxyproline; Lactic Aci | 2012 |
The mechanism of taurine protection against endoplasmic reticulum stress in an animal stroke model of cerebral artery occlusion and stroke-related conditions in primary neuronal cell culture.
Topics: Activating Transcription Factor 6; Animals; Apoptosis; Brain Ischemia; Caspase 12; Caspase 3; Cell S | 2013 |
Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study.
Topics: Analysis of Variance; Animals; Asparagine; Aspartic Acid; Brain Ischemia; Cerebral Hemorrhage; Chrom | 2003 |
Volume-regulated anion channels are the predominant contributors to release of excitatory amino acids in the ischemic cortical penumbra.
Topics: Amino Acid Transport System X-AG; Animals; Anion Transport Proteins; Aspartic Acid; Astrocytes; Brai | 2004 |
A word on hypothermic preconditioning.
Topics: Animals; Brain Ischemia; Cell Survival; Hypothermia, Induced; Ischemic Preconditioning; Purkinje Cel | 2004 |
Glycine-induced neurotoxicity in organotypic hippocampal slice cultures.
Topics: Alanine; Animals; Animals, Newborn; Brain Ischemia; Dose-Response Relationship, Drug; Drug Resistanc | 2005 |
[Effects of tianma gouteng fang on transmitter amino acids in the hippocampus extracellular liquids in freely moving rats subjected to brain ischemia].
Topics: Animals; Arginine; Brain Ischemia; Drug Combinations; Drugs, Chinese Herbal; Excitatory Amino Acids; | 2004 |
[Effects of taurine on early changes of excitatory amino acids in rabbit brain due to deep hypothermic circulatory arrest].
Topics: Animals; Brain Ischemia; Disease Models, Animal; Excitatory Amino Acids; Extracorporeal Circulation; | 2005 |
Taurine attenuates D-[3H]aspartate release evoked by depolarization in ischemic corticostriatal slices.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship | 2006 |
Cerebroprotective effect of a new taurine derivative during cerebral ischemia.
Topics: Animals; Brain Ischemia; Energy Metabolism; Lipid Peroxidation; Neuroprotective Agents; Rats; Taurin | 2006 |
Effect of taurine on gastric oxidative stress and hemorrhagic erosion in brain ischemic rats.
Topics: Animals; Brain Ischemia; Gastric Juice; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Oxidative | 2006 |
Taurine release in mouse brain stem slices under cell-damaging conditions.
Topics: 2,4-Dinitrophenol; Animals; Brain Ischemia; Brain Stem; Calcium Signaling; Cyclic GMP; Female; Guany | 2007 |
Effects of taurine on cerebral blood flow perfusion, cell apoptosis, and infarct volume in acute cerebral ischemic rats.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Caspase 3; Cerebrovascular Circulation; In Situ Nick-End | 2006 |
Involvement of taurine in cerebral ischemia and electroacupuncture anti-ischemia.
Topics: Animals; bcl-2-Associated X Protein; Brain; Brain Ischemia; Cell Survival; Electroacupuncture; In Si | 2006 |
Neuroprotective effect of a new taurinamide derivative--Taurepar.
Topics: Amides; Amino Acids; Animals; Brain Ischemia; Male; Neuroprotective Agents; Piracetam; Rats; Rats, W | 2006 |
Direct correlation between ischemic injury and extracellular glycine concentration in mice with genetically altered activities of the glycine cleavage multienzyme system.
Topics: Alanine; Amino Acid Oxidoreductases; Animals; Brain Ischemia; Carrier Proteins; Cerebrovascular Circ | 2007 |
Nitric oxide is involved in taurine release in the mouse brain stem under normal and ischemic conditions.
Topics: Aging; Animals; Brain Ischemia; Brain Stem; Mice; Nitric Oxide; Taurine | 2008 |
Neuroprotective mechanism of taurine due to up-regulating calpastatin and down-regulating calpain and caspase-3 during focal cerebral ischemia.
Topics: Animals; Apoptosis; Brain Ischemia; Calcium-Binding Proteins; Calpain; Caspase 3; Dose-Response Rela | 2008 |
Neurotransmitter amino acids in the CNS. I. Regional changes in amino acid levels in rat brain during ischemia and reperfusion.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Circulation; ga | 1984 |
Guanidinoethane sulfate is neuroprotective towards delayed CA1 neuronal death in gerbils.
Topics: Animals; Brain Ischemia; Cell Death; Gerbillinae; Hippocampus; Male; Neurons; Neuroprotective Agents | 1995 |
Aminoacid recovery via microdialysis and photoinduced focal cerebral ischemia in brain cortex of rats.
Topics: Amino Acids; Animals; Apoptosis; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Glutamic A | 1995 |
Blood-brain barrier taurine transport during osmotic stress and in focal cerebral ischemia.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Blood-Brain Barrier; Brain Ischemia; Homeostas | 1995 |
Excitatory amino acids in the cerebrospinal fluid of asphyxiated infants: relationship to hypoxic-ischemic encephalopathy.
Topics: Amino Acids; Aspartic Acid; Asphyxia Neonatorum; Brain Ischemia; Child, Preschool; Chromatography, L | 1993 |
In vivo acidosis reduces extracellular concentrations of taurine and glutamate in the rat hippocampus.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Animals; Antiporters; Bicarbonates; Brai | 1994 |
In situ changes in purine nucleotide and N-acetyl concentrations upon inducing global ischemia in cat brain.
Topics: Acetylation; Adenosine; Animals; Aspartic Acid; Brain Ischemia; Cats; Choline; Creatine; Female; gam | 1993 |
Sustained changes in acetylcholine and amino acid contents of brain regions following microsphere embolism in rats.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebral Cortex; Corpus S | 1993 |
Effects of repeated cerebral ischemia on extracellular amino acid concentrations measured with intracerebral microdialysis in the gerbil hippocampus.
Topics: Amino Acids; Animals; Brain Ischemia; Disease Models, Animal; Extracellular Space; gamma-Aminobutyri | 1993 |
Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Brain Ischemia; Cerebral Cortex | 1996 |
Enhanced taurine release in cell-damaging conditions in the developing and ageing mouse hippocampus.
Topics: Aging; Animals; Animals, Newborn; Brain Ischemia; Cell Survival; Female; Hippocampus; Hypoxia; Male; | 1997 |
Effects of electroacupuncture on extracellular contents of amino acid neurotransmitters in rat striatum following transient focal cerebral ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Infarction; Chromatography, High Pressure Liquid; C | 1997 |
Release of endogenous glutamate, aspartate, GABA, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions.
Topics: Aging; Animals; Aspartic Acid; Brain Ischemia; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippo | 1998 |
Changes in brain organic osmolytes in experimental cerebral ischemia.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Brain Ischemia; Creatine; Disease Mod | 1998 |
Mechanisms of ischemia-induced taurine release in mouse hippocampal slices.
Topics: Animals; Brain Ischemia; Enzyme Inhibitors; Female; Hippocampus; In Vitro Techniques; Ion Transport; | 1998 |
Modulation of ischemia-evoked release of excitatory and inhibitory amino acids by adenosine A1 receptor agonist.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; gamma-Aminobutyric Acid; Glut | 1998 |
Attenuated neurotransmitter release and spreading depression-like depolarizations after focal ischemia in mutant mice with disrupted type I nitric oxide synthase gene.
Topics: Alanine; Animals; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cortical | 1998 |
Effects of hyperosmolarity and ion substitutions on amino acid efflux from the ischemic rat cerebral cortex.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain Edema; Brain Ischemia; Cerebral Cortex; Chlorides | 1999 |
Lactate reduces amino acid release and fuels recovery of function in the ischemic brain.
Topics: Amino Acids; Animals; Brain Ischemia; Cerebral Cortex; Electroencephalography; Injections; Lactic Ac | 1999 |
Striatal outflow of adenosine, excitatory amino acids, gamma-aminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion: correlations with neurological deficit and histopathological damage.
Topics: Adenosine; Animals; Arterial Occlusive Diseases; Brain Ischemia; Cerebral Cortex; Chromatography, Hi | 1999 |
Characteristics of ischemia-induced taurine release in the developing mouse hippocampus.
Topics: Animals; beta-Alanine; Brain Ischemia; Carrier Proteins; Female; Hippocampus; In Vitro Techniques; K | 1999 |
Hyperglycemia enhances extracellular glutamate accumulation in rats subjected to forebrain ischemia.
Topics: Alanine; Animals; Brain Ischemia; Glutamic Acid; Glutamine; Glycine; Hyperglycemia; Male; Prosenceph | 2000 |
Anticonvulsant taurine derivatives modify taurine and GABA release in the mouse hippocampus.
Topics: Aging; Animals; Anticonvulsants; Brain Ischemia; Female; gamma-Aminobutyric Acid; Hippocampus; In Vi | 1999 |
Enhanced taurine release in cultured cerebellar granule cells in cell-damaging conditions.
Topics: Animals; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Excitatory | 1999 |
Topical glucose and accumulation of excitotoxic and other amino acids in ischemic cerebral cortex.
Topics: Animals; Aspartic Acid; Blood Pressure; Brain Ischemia; Carbon Dioxide; Cerebral Cortex; Ethanolamin | 2000 |
Modulation of the ischemia-induced taurine release by adenosine receptors in the developing and adult mouse hippocampus.
Topics: Age Factors; Animals; Animals, Newborn; Brain Ischemia; Female; Hippocampus; In Vitro Techniques; Ma | 2000 |
Transporter reversal as a mechanism of glutamate release from the ischemic rat cerebral cortex: studies with DL-threo-beta-benzyloxyaspartate.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain I | 2000 |
The effect of topical insulin on the release of excitotoxic and other amino acids from the rat cerebral cortex during streptozotocin-induced hyperglycemic ischemia.
Topics: Administration, Topical; Animals; Aspartic Acid; Blood Glucose; Brain Ischemia; Cerebral Cortex; Dia | 2000 |
Involvement of metabotropic glutamate receptors in ischemia-induced taurine release in the developing and adult hippocampus.
Topics: Aging; Animals; Brain Ischemia; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitat | 2000 |
[The neuroprotective effect of the glutamate antagonist acamprosate following experimental cerebral ischemia. A study with the lipid peroxidase inhibitor u-101033e].
Topics: Acamprosate; Alcohol Deterrents; Anesthetics, Intravenous; Animals; Brain Ischemia; Enzyme Inhibitor | 2000 |
Hypothermia inhibits ischemia-induced efflux of amino acids and neuronal damage in the hippocampus of aged rats.
Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Cerebrovascular Circulation; Ex | 2000 |
Observations on the relationship between the extracellular changes of taurine and glutamate during cortical spreading depression, during ischemia, and within the area surrounding a thrombotic infarct.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Cortical Spreading Depression; Extracellular Space; Gl | 2000 |
Real-time, two-dimensional visualization of ischaemia-induced glutamate release from hippocampal slices.
Topics: Alanine; Aspartic Acid; Brain Ischemia; Calcium Signaling; Cell Line; Computer Systems; Dentate Gyru | 2001 |
Alterations of amino acid levels from striatum, hippocampus, and cerebral cortex induced by global cerebral ischemia in gerbil.
Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; | 2000 |
Involvement of ion channels in ischemia-induced taurine release in the mouse hippocampus.
Topics: Animals; Brain Ischemia; Chloride Channels; Culture Techniques; Female; Hippocampus; Ion Channels; M | 2000 |
Taurine release in the developing and adult mouse hippocampus: involvement of cyclic guanosine monophosphate.
Topics: Aging; Animals; Animals, Newborn; Brain Ischemia; Cyclic AMP; Enzyme Inhibitors; Female; Hippocampus | 2002 |
Ischemia-induced taurine release is modified by nitric oxide-generating compounds in slices from the developing and adult mouse hippocampus.
Topics: Age Factors; Animals; Brain Ischemia; Hippocampus; In Vitro Techniques; Mice; Nitric Oxide; Nitric O | 2002 |
Concomitant increases in the extracellular concentrations of excitatory and inhibitory amino acids in the rat hippocampus during forebrain ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Cell Death; Consciousness; Ethanolamines | 1992 |
Extracellular acidic sulfur-containing amino acids and gamma-glutamyl peptides in global ischemia: postischemic recovery of neuronal activity is paralleled by a tetrodotoxin-sensitive increase in cysteine sulfinate in the CA1 of the rat hippocampus.
Topics: Acids; Amino Acids; Animals; Brain Ischemia; Cysteine; Dipeptides; Electrochemistry; Extracellular S | 1991 |
Extracellular overflow of glutamate, aspartate, GABA and taurine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Asphyxia; Brain Ischemia; Cerebrovascular Circulation; Evoked P | 1987 |
Ischemia-induced shift of inhibitory and excitatory amino acids from intra- to extracellular compartments.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Electroencephalography; Extracellular Space; ga | 1985 |