taurine has been researched along with Brain Edema in 30 studies
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Significantly higher CMD-taurine levels were found in patients with brain edema or DCI after aneurysmal subarachnoid hemorrhage." | 7.81 | Cerebral Taurine Levels are Associated with Brain Edema and Delayed Cerebral Infarction in Patients with Aneurysmal Subarachnoid Hemorrhage. ( Beer, R; Broessner, G; Ferger, B; Hackl, W; Helbok, R; Kofler, M; Lackner, P; Pfausler, B; Rhomberg, P; Schiefecker, A; Schmutzhard, E; Sohm, F; Thomé, C, 2015) |
| " Severe hyponatremia and hypoosmolality induced profound decreases in levels of brain electrolytes, amino acids (especially taurine), and creatine." | 7.67 | Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain. ( Hauhart, RE; Nelson, JS; Thurston, JH, 1987) |
| "In aneurysmal subarachnoid hemorrhage, taurine may be a warning signal informing of the risk of death in a patient." | 6.58 | Taurine and aneurysmal subarachnoid hemorrhage prognosis. ( Diéguez-Campa, CE; Pérez-Neri, I, 2018) |
| "Toxic brain edema was induced in rats with intraperitoneal injection of tetra-ethyl lead (10 mg per kg of animal weight)." | 5.42 | [The effects of taurine on oxidative processes in brain edema]. ( Hovsepyan, LM; Melkonyan, MM; Zakaryan, AV; Zakaryan, GV, 2015) |
| "By contrast, rats with hepatic encephalopathy (HE) following administration of a hepatotoxin, thioacetamide, were characterized by CC edema and an increased Tau content in both BG and CC." | 5.29 | Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure. ( Albrecht, J; Hilgier, W; Olson, JE, 1996) |
| "Taurine is a cerebral osmoprotective molecule during chronic hypernatremic dehydration." | 5.28 | Taurine and osmoregulation. III. Taurine deficiency protects against cerebral edema during acute hyponatremia. ( del Pizzo, R; Sturman, JA; Trachtman, H, 1990) |
| "Significantly higher CMD-taurine levels were found in patients with brain edema or DCI after aneurysmal subarachnoid hemorrhage." | 3.81 | Cerebral Taurine Levels are Associated with Brain Edema and Delayed Cerebral Infarction in Patients with Aneurysmal Subarachnoid Hemorrhage. ( Beer, R; Broessner, G; Ferger, B; Hackl, W; Helbok, R; Kofler, M; Lackner, P; Pfausler, B; Rhomberg, P; Schiefecker, A; Schmutzhard, E; Sohm, F; Thomé, C, 2015) |
| " Moreover, it lowered brain edema and blood-brain barrier permeability, enhanced activity of superoxide dismutase and the level of glutathione, and reduced levels of malondialdehyde and lactic acid in traumatic tissue 24 h after CHI." | 3.81 | Protective effects of taurine against closed head injury in rats. ( Gu, Y; Sun, M; Zhang, Y; Zhao, Y, 2015) |
| " The decreased levels of taurine, hypoxanthine, and xanthine may reflect reduced posttraumatic brain edema, whereas the increased level of glutamate could account for the elevated water content observed in the nontraumatized hemisphere." | 3.70 | Significant reduction in brain swelling by administration of nonpeptide kinin B2 receptor antagonist LF 16-0687Ms after controlled cortical impact injury in rats. ( Dohse, NK; Stover, JF; Unterberg, AW, 2000) |
| " Severe hyponatremia and hypoosmolality induced profound decreases in levels of brain electrolytes, amino acids (especially taurine), and creatine." | 3.67 | Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain. ( Hauhart, RE; Nelson, JS; Thurston, JH, 1987) |
| "In aneurysmal subarachnoid hemorrhage, taurine may be a warning signal informing of the risk of death in a patient." | 2.58 | Taurine and aneurysmal subarachnoid hemorrhage prognosis. ( Diéguez-Campa, CE; Pérez-Neri, I, 2018) |
| "Toxic brain edema was induced in rats with intraperitoneal injection of tetra-ethyl lead (10 mg per kg of animal weight)." | 1.42 | [The effects of taurine on oxidative processes in brain edema]. ( Hovsepyan, LM; Melkonyan, MM; Zakaryan, AV; Zakaryan, GV, 2015) |
| "Taurine, was synthesized and retained intracellularly during DKA-like hypertonicity, and released during hypotonicity, in part mitigating neuronal swelling." | 1.38 | An in vitro paradigm for diabetic cerebral oedema and its therapy: a critical role for taurine and water channels. ( Cameron, FJ; Higgins, S; Koves, IH; Mishra, A; Pitt, J; Russo, VC; Werther, GA, 2012) |
| "Type 1 diabetes is a prevalent chronic disease in childhood with the commonest single cause of death being cerebral oedema in the context of diabetic ketoacidosis (DKA)." | 1.33 | Insights into the acute cerebral metabolic changes associated with childhood diabetes. ( Cameron, FJ; Inder, TE; Kean, MJ; Neil, JJ; Wellard, RM; Werther, GA, 2005) |
| "Myo-inositol levels were strongly decreased already at 3h after treatment with NH4Cl; other intracellular osmolytes, such as hypotaurine and choline-containing compounds were also decreased, along with a concomitant increase of both the total concentration and the amount of newly synthesized glutamine, alanine, and glutathione." | 1.33 | Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response. ( Leibfritz, D; Zwingmann, C, 2005) |
| "Taurine release was most affected, exhibiting a greater than 9-fold increase during the hyposmotic stimulus." | 1.30 | Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases. ( Estevez, AY; O'Regan, MH; Phillis, JW; Song, D, 1999) |
| " There was no abnormal locomotor activity in the L-CPA rats treated with MK-801 except for the first 4 hr following dosing when animals were severely sedated." | 1.29 | L-2-chloropropionic acid-induced neurotoxicity is prevented by MK-801: possible role of NMDA receptors in the neuropathology. ( Gyte, A; Lock, EA; Simpson, MG; Widdowson, PS; Wyatt, I, 1996) |
| "By contrast, rats with hepatic encephalopathy (HE) following administration of a hepatotoxin, thioacetamide, were characterized by CC edema and an increased Tau content in both BG and CC." | 1.29 | Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure. ( Albrecht, J; Hilgier, W; Olson, JE, 1996) |
| "Taurine is a cerebral osmoprotective molecule during chronic hypernatremic dehydration." | 1.28 | Taurine and osmoregulation. III. Taurine deficiency protects against cerebral edema during acute hyponatremia. ( del Pizzo, R; Sturman, JA; Trachtman, H, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 10 (33.33) | 18.2507 |
| 2000's | 11 (36.67) | 29.6817 |
| 2010's | 8 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pérez-Neri, I | 1 |
| Diéguez-Campa, CE | 1 |
| Kofler, M | 1 |
| Schiefecker, A | 1 |
| Ferger, B | 1 |
| Beer, R | 1 |
| Sohm, F | 1 |
| Broessner, G | 1 |
| Hackl, W | 1 |
| Rhomberg, P | 1 |
| Lackner, P | 1 |
| Pfausler, B | 1 |
| Thomé, C | 1 |
| Schmutzhard, E | 1 |
| Helbok, R | 1 |
| Hovsepyan, LM | 1 |
| Zakaryan, GV | 1 |
| Melkonyan, MM | 1 |
| Zakaryan, AV | 1 |
| Wang, Q | 1 |
| Fan, W | 1 |
| Cai, Y | 1 |
| Wu, Q | 1 |
| Mo, L | 1 |
| Huang, Z | 1 |
| Huang, H | 1 |
| Zhang, Z | 1 |
| Yu, R | 1 |
| Cao, L | 1 |
| Haskew-Layton, RE | 1 |
| Rudkouskaya, A | 1 |
| Jin, Y | 1 |
| Feustel, PJ | 1 |
| Kimelberg, HK | 2 |
| Mongin, AA | 2 |
| Koves, IH | 1 |
| Russo, VC | 1 |
| Higgins, S | 1 |
| Mishra, A | 1 |
| Pitt, J | 1 |
| Cameron, FJ | 2 |
| Werther, GA | 2 |
| Bodega, G | 1 |
| Suárez, I | 1 |
| López-Fernández, LA | 1 |
| García, MI | 1 |
| Köber, M | 1 |
| Penedo, M | 1 |
| Luna, M | 1 |
| Juárez, S | 1 |
| Ciordia, S | 1 |
| Oria, M | 1 |
| Córdoba, J | 1 |
| Fernández, B | 1 |
| Sun, M | 1 |
| Zhao, Y | 1 |
| Gu, Y | 1 |
| Zhang, Y | 1 |
| Zwingmann, C | 2 |
| Chatauret, N | 1 |
| Rose, C | 1 |
| Leibfritz, D | 2 |
| Butterworth, RF | 2 |
| Kean, MJ | 1 |
| Wellard, RM | 1 |
| Neil, JJ | 1 |
| Inder, TE | 1 |
| Law, RO | 1 |
| Ritz, MF | 1 |
| Schmidt, P | 1 |
| Mendelowitsch, A | 1 |
| Westergren, I | 1 |
| Nyström, B | 1 |
| Hamberger, A | 1 |
| Johansson, BB | 1 |
| Widdowson, PS | 1 |
| Wyatt, I | 1 |
| Gyte, A | 1 |
| Simpson, MG | 1 |
| Lock, EA | 1 |
| Hilgier, W | 1 |
| Olson, JE | 2 |
| Albrecht, J | 1 |
| Fujikawa, DG | 1 |
| Kim, JS | 1 |
| Daniels, AH | 1 |
| Alcaraz, AF | 1 |
| Sohn, TB | 1 |
| Stover, JF | 4 |
| Morganti-Kosmann, MC | 1 |
| Lenzlinger, PM | 1 |
| Stocker, R | 1 |
| Kempski, OS | 1 |
| Kossmann, T | 1 |
| Phillis, JW | 2 |
| Song, D | 2 |
| O'Regan, MH | 2 |
| Estevez, AY | 1 |
| Dohse, NK | 1 |
| Unterberg, AW | 3 |
| Beyer, TF | 1 |
| Li, G | 1 |
| Liu, Y | 1 |
| Rose, SJ | 1 |
| Bushi, M | 1 |
| Nagra, I | 1 |
| Davies, WE | 1 |
| Trachtman, H | 1 |
| del Pizzo, R | 1 |
| Sturman, JA | 1 |
| Thurston, JH | 1 |
| Hauhart, RE | 1 |
| Nelson, JS | 1 |
3 reviews available for taurine and Brain Edema
| Article | Year |
|---|---|
Taurine and aneurysmal subarachnoid hemorrhage prognosis.
Topics: Biomarkers; Brain Edema; Humans; Prognosis; Subarachnoid Hemorrhage; Taurine; Vasospasm, Intracrania | 2018 |
Taurine in hepatic encephalopathy.
Topics: Animals; Biomarkers; Brain; Brain Edema; Hepatic Encephalopathy; Humans; Intracranial Pressure; Live | 1996 |
Swelling-activated release of excitatory amino acids in the brain: relevance for pathophysiology.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1998 |
27 other studies available for taurine and Brain Edema
| Article | Year |
|---|---|
Cerebral Taurine Levels are Associated with Brain Edema and Delayed Cerebral Infarction in Patients with Aneurysmal Subarachnoid Hemorrhage.
Topics: Aged; Biomarkers; Brain Edema; Cerebral Infarction; Chromatography, Liquid; Female; Humans; Intracra | 2015 |
[The effects of taurine on oxidative processes in brain edema].
Topics: Animals; Brain; Brain Edema; Free Radicals; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; | 2015 |
Protective effects of taurine in traumatic brain injury via mitochondria and cerebral blood flow.
Topics: Animals; Blood Flow Velocity; Brain Edema; Brain Injuries, Traumatic; Cerebrovascular Circulation; D | 2016 |
Neuroprotection of taurine through inhibition of 12/15 lipoxygenase pathway in cerebral ischemia of rats.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Brain Edema; Brain Infarction; | 2017 |
Two distinct modes of hypoosmotic medium-induced release of excitatory amino acids and taurine in the rat brain in vivo.
Topics: Animals; Astrocytes; Brain; Brain Edema; Cells, Cultured; Excitatory Amino Acids; Male; Neurons; Osm | 2008 |
An in vitro paradigm for diabetic cerebral oedema and its therapy: a critical role for taurine and water channels.
Topics: Aquaporins; Base Sequence; Brain Edema; Cell Line, Tumor; Diabetes Complications; DNA Primers; Human | 2012 |
Ammonia induces aquaporin-4 rearrangement in the plasma membrane of cultured astrocytes.
Topics: alpha-Synuclein; Ammonia; Animals; Aquaporin 4; Astrocytes; Brain Edema; Cell Membrane; Cells, Cultu | 2012 |
Protective effects of taurine against closed head injury in rats.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Cell Death; Dose-Response Relationship, Drug; Glutathione | 2015 |
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia.
Topics: Animals; Brain Edema; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Hypothermia, Induce | 2004 |
Insights into the acute cerebral metabolic changes associated with childhood diabetes.
Topics: Adolescent; Brain; Brain Edema; Child; Diabetes Mellitus, Type 1; Female; Humans; Magnetic Resonance | 2005 |
Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response.
Topics: Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Animals, Newborn; Astrocytes; Brain Edema | 2005 |
Cerebrocellular swelling in the presence of uraemic guanidino compounds: ameliorative effects of taurine.
Topics: Animals; Brain Edema; Guanidine; Male; Neuroprotective Agents; Nitrosation; Oxidative Stress; Rats; | 2005 |
Effects of isoflurane on glutamate and taurine releases, brain swelling and injury during transient ischemia and reperfusion.
Topics: Anesthetics; Animals; Brain Edema; Glutamic Acid; Ischemic Attack, Transient; Isoflurane; Male; Neur | 2006 |
Amino acids in extracellular fluid in vasogenic brain edema.
Topics: Amino Acids; Animals; Blood-Brain Barrier; Brain Edema; Dose-Response Relationship, Drug; Ethanolami | 1994 |
L-2-chloropropionic acid-induced neurotoxicity is prevented by MK-801: possible role of NMDA receptors in the neuropathology.
Topics: Administration, Oral; Animals; Aspartic Acid; Autoradiography; Brain Edema; Cerebellum; Dizocilpine | 1996 |
Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure.
Topics: Ammonia; Animals; Basal Ganglia; Body Water; Brain Edema; Cerebral Cortex; Hepatic Encephalopathy; I | 1996 |
In vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons.
Topics: Amygdala; Animals; Aspartic Acid; Brain Edema; Extracellular Space; Glutamic Acid; Glutamine; Glycin | 1996 |
Glutamate and taurine are increased in ventricular cerebrospinal fluid of severely brain-injured patients.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Brain Concussion; Brain Edema; Brain Injuries; Cerebr | 1999 |
Effects of hyperosmolarity and ion substitutions on amino acid efflux from the ischemic rat cerebral cortex.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain Edema; Brain Ischemia; Cerebral Cortex; Chlorides | 1999 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebra | 1999 |
Significant reduction in brain swelling by administration of nonpeptide kinin B2 receptor antagonist LF 16-0687Ms after controlled cortical impact injury in rats.
Topics: Analysis of Variance; Animals; Body Water; Bradykinin Receptor Antagonists; Brain Chemistry; Brain E | 2000 |
Increased cerebrospinal fluid glutamate and taurine concentrations are associated with traumatic brain edema formation in rats.
Topics: Amino Acids; Animals; Body Water; Brain; Brain Edema; Brain Injuries; Glutamic Acid; Male; Osmolar C | 2000 |
Riluzole reduces brain swelling and contusion volume in rats following controlled cortical impact injury.
Topics: Animals; Body Water; Brain; Brain Edema; Brain Injuries; Cerebral Cortex; Glutamic Acid; Hypoxanthin | 2000 |
Calcium/calmodulin-modulated chloride and taurine conductances in cultured rat astrocytes.
Topics: Animals; Astrocytes; Brain Edema; Calcium; Calcium Channel Blockers; Calmodulin; Cells, Cultured; Ch | 2002 |
Taurine fluxes in insulin dependent diabetes mellitus and rehydration in streptozotocin treated rats.
Topics: Animals; Brain; Brain Edema; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Ke | 2000 |
Taurine and osmoregulation. III. Taurine deficiency protects against cerebral edema during acute hyponatremia.
Topics: Animals; Brain Edema; Cats; Hyponatremia; Osmolar Concentration; Taurine | 1990 |
Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain.
Topics: Acclimatization; Adenine Nucleotides; Amino Acids; Animals; Brain; Brain Edema; Creatine; Demyelinat | 1987 |